Engineering innovative solutions for 21st century medicine
In 2006 in the UK, there were 130,000 hip and knee
replacement operations but demand is growing all ... from ultrasound scanning in pregnancy to hip and knee
replacements. The opportunities for engineers and ... we will create the next generation of hip and knee
replacement implants that will last longer and ...
Non-wovens as scaffolds for artificial tissue
... is available in German .
When someone's knee
hurts with every step it's a sign that the ... tissue artificially so that patients with such knee
problems can walk free of pain again. The aim is ... artificial cartilage is inserted in the patient's knee
the supporting scaffold is gradually resorbed and ...
Exercise after knee replacement critical
... to strengthen your quadriceps after you've had knee
replacement surgery due to osteoarthritis is ... In fact, it can boost the function of your new knee
to nearly that of a healthy adult your age.
... sounds logical that exercises to strengthen your knee
should be a component of your post-operative ...
Exercise no danger for joints
... Hospital. "The largest modifiable risk factor for knee
OA is body weight, such that each additional ... body mass increases the compressive load over the knee
by roughly 4kg".
One might surmise therefore ... the risk of OA, rather than increase it.
is the joint most commonly affected by the ...
Technique used in human ankle injuries modified to treat dogs' knees
... the tibia bone to stabilize the CCL-deficient knee
in these dogs. Now, a new minimally invasive ... do not occur because of a single trauma to the knee
but are the result of a degenerative process that ... of a device that stabilizes the CCL-deficient knee
through bone tunnels drilled using very small ...
Research examines factors in delaying or declining total knee replacement surgery
... choose to postpone but ultimately undergo total knee
replacement surgery and emphasizes the need for ... pre-and post operative experiences with total knee
replacement surgery, says Jacobson. These ... studies of total joint replacement of the hip or knee
indicate that eligible patients delay or decline ...
Listen-up ladies: Don't postpone knee-replacement surgery
... Doctors typically tell patients to wait to have knee
replacements until they just can't stand the pain ... in McKinly Laboratory, 229 candidates for total knee
replacements, including 95 men and 126 women with ... straightens the knee--and range of motion of the knee
also were assessed at the UD clinic, which ...
Osteoarthritis risk linked to finger length ratio
... between the 2D: 4D ratio and the risk of knee
and hip OA. Their findings suggest that having a ... with no radiographic evidence of hip or knee
OA, no present hip or knee
symptoms, and no history of joint disease or ...
Researchers win award for best clinical paper in orthopedic physical therapy
... with Anterior Cruciate Ligament Injury: Part 2: Determinants of Dynamic knee
Stability," was published in the January 2008 issue of the American ... therapy.
The approach is based on the stability of the patient's knee
while doing a series of simple hop tests.
The tool, which has been ...
Fly studies reveal immune cell responses to tumor and tissue damage
... September 17, 2008, Cambridge, UK
scrapes and tumor growth might have more in common than you think.
The ... supports the idea that the same cellular mechanisms which heal a skinned knee
might also have a role in preventing the growth of tumors. A report ...
Researchers coat titanium with polymer to improve integration of joint replacements
... Research Center on the Engineering of Living Tissues.
and hip replacements typically last about 15 years until the components ... joint. With approximately 40 percent of the 712,000 total hip and knee
replacements in the United States in 2004 performed on younger patients ...
'Wildcat Power Cord' repairs cruciate ligament in dairy cow's knee
... a breeding injury in December 2007 when the cruciate ligament in her right knee
ruptured. Dr. David Anderson, professor and head of agricultural practices ... The cruciate ligament is a dense tissue that connects the bones in the knee
joint. Injuring it can be career-ending and often life-ending - until now, ...
Herr receives Heinz Award for Technology, the Economy and Employment
... of numerous patents, including the Computer-Controlled Artificial knee
(commercially available as the Rheo Knee), the Active Ankle-Foot Orthosis, ... and forward in walking.
At age 17, Dr. Herr lost both legs below the knee
in a mountain climbing accident, but returned to the classroom after a few ...
Knee injuries may start with strain on the brain, not the muscles
... ANN ARBOR, Mich.---New research shows that training your brain may be just as effective as training your muscles in preventing ACL knee
injuries, and suggests a shift from performance-based to prevention-based athletic training programs.
The ACL, or anterior cruciate ligament, is ...
Stem cell surprise for tissue regeneration
... true upon injury, after which the repair process requires muscle stem cells to make new muscles. For this, they injured the leg muscles between the knee
and ankle. They were again surprised that these muscle stem cells, without the two key embryonic muscle stem cell genes, could generate muscles as ...
Promising 3-year data: Saving limbs with drug-eluting stents
... 34th Annual Scientific Meeting.
"This is encouraging news for PAD patients with critical limb ischemia. The smaller blood vessels below the knee
are more difficult to treat due to their size (3 millimeters) and are more prone to reclog than larger vessels. The use of drug-eluting stents in the ...
Metastatic bone disease patients can walk in Lazarus' footsteps
... pain, and 43 (53 percent) could stop taking other pain medication. In this study, pelvic, femur, sacrum, ribs, homerus, scapula, tibia, pubis and knee
bones were treated.
In one case, Anselmetti recounted, a 79-year-old Roman Catholic nun had severe pain and was bedridden because of cancerous ...
Society of Interventional Radiology hosts 34th annual scientific meeting
... arterial disease (PAD) patients with critical limb ischemia avoid amputation by exploring the treatment of the smaller blood vessels below the knee
(typically difficult to treat because of their size) with drug-coated stents. Promising three-year data from a double-arm prospective registry will ...
Research model may one day 'inoculate' elderly against slip-related falls
... Pai said. The researchers also found that the trained group unconsciously changed their gait. They used a flatter landing foot and bent the landing knee
more. These changes reduced the landing force and the velocity of the slip. Interestingly, the trained group did this while walking at their ...
Disability Rights Legal Center honors Ossur
... industry into the Bionic age of prosthetics with Ossur's successful market entry via three groundbreaking product launches: the Rheo Knee, the Power knee
and the Proprio Foot. All three products have gained international recognition and acclaim.
There to present the award was April Holmes, the ...
UNC scientists teach enzyme to make synthetic heparin in more varieties
... substance is most often used during and after procedures such as kidney dialysis, heart bypass surgery, stent implantation, indwelling catheters, and knee
and hip replacements to prevent clots from blocking or restricting the flow of blood. The annual worldwide sales of heparin are estimated at $3 ...
Study: Elderly Women can increase strength but still risk falls
... strength of 25 young (18 33) and 24 old (65 84) inactive women then had both groups participate in resistance training on a machine that targeted knee
extensor muscles, which are critical for walking, stair-climbing, or rising from a chair. "They're what let you live on your own," he says.
Low-gravity training machine reduces joint, muscle impacts, says CU-Boulder study
... their body weight.
The new study has implications for both competitive runners rehabilitating from injuries and for ordinary people returning from knee
and hip surgeries, according to Associate Professor Rodger Kram of CU-Boulder's integrative physiology department.
Known as the "G-Trainer," the ...
Scientists to discover why flamingos are in the pink of health -- in the poo!
... slums of Bombay.
In Porbandar, the city which is the birthplace of Mahatma Ghandi, in Gujarat to the north of Bombay, I watched 8,000 standing knee
deep and happily filtering-feeding in the water alongside rubbish, cowpats and wastewater running in from surrounding houses and factories.
UVa biomedical engineering study shows magnetic field can reduce swelling
Lack of regulation and widespread public acceptance have turned magnetic therapy into a $5 billion world market. Hopeful consumers buy bracelets, knee
braces, shoe inserts, mattresses and other products that are embedded with magnets based on anecdotal evidence, hoping for a non-invasive and ...
Researchers create system to build transplant tissue
... individual cells. The so-called gel scaffold can hold tens of millions of living cells per milliliter in a 3-D arrangement, such as in the shape of a knee
meniscus, to create a template for tissue to form.
In theory, the system could accommodate many kinds of tissue.
"A significant impediment to ...
'Jumping genes' could make for safer gene delivery system
... In July, for example, a 36-year-old Illinois woman died after experimental gene therapy treatment in which an engineered virus was injected into her knee
to treat rheumatoid arthritis. The viruses used were engineered to suppress the immune system only in the knee. In the case of rheumatoid arthritis, ...
21st-century pack mule: MIT's 'exoskeleton' lightens the load
... that run up the leg to the backpack, transferring the weight of the backpack to the ground. Springs at the ankle and hip and a damping device at the knee
allow the device to approximate the walking motion of a human leg, with a very small external power input (one watt).
Other research teams have ...
Bioengineers at University of Pennsylvania devise nanoscale system to measure cellular forces
... point that leads not to a local response but to a remote response from the cells internal forces, akin to tickling the cells elbow and watching the knee
The cell senses the force that we apply and adjusts its own internal forces to compensate, Chris Chen, an associate professor in the ...
Genetics determine optimal drug dose of common anticoagulant
... is often prescribed after major orthopedic surgery to prevent blood clots in the legs, the study followed 92 adults undergoing either total hip or knee
replacement at the Washington University Medical Center, who had never previously taken the anticoagulant.
Prior to warfarin treatment, the ...
JCI table of contents: Aug. 16, 2007
... disorder that is characterized by the presence of lumps of calcium at inappropriate sites in the body, such as around the hip, elbow, shoulder, and knee
joints. Previously, mutations in two genes (FGF23 and GALNT3) had been shown to cause this disease. Now, researchers from Indiana University School ...
Robot assisted surgery more accurate than conventional surgery
... Imperial College London shows that robot assisted knee
surgery is significantly more accurate than ... surgical outcomes for patients undergoing partial knee
replacement. Acrobot works by helping the surgeon to line up the replacement knee
parts with the existing bones.
The surgeons ...
Bones in motion: Brown scientists to create new 3-D X-ray system
... An orthopedic surgeon trying to figure out the best way to repair a torn knee
ligament or an evolutionary biologist tracing the disappearance of digits ... approaches;
creating better treatments for shoulder, wrist, knee
and back injuries;
driving innovations in computer graphics and ...
Bioengineered tissue implants regenerate damaged knee cartilage
cartilage injuries can be effectively repaired by ... and mature when implanted into patients with a knee
injury. The novel tissue engineering approach ... with pre-existing early osteoarthritis of the knee
secondary to traumatic injury. Maturation of the ...
Matrilin-3 gene discovered to prevent onset of osteoarthritis
... the mice lacking matrilin-3 showed significantly higher BMD both in the knee
joint and throughout the body at 18 weeks of age, the time when mice ... bone density. Clinical studies in humans have shown that the prevalence of knee
and hip osteoarthritis increases with increasing BMD.
"Our study ...
New MRI technique quickly builds 3-D images of knees
... the burgeoning group of older adults with osteoarthritis-related knee
problems - and can help researchers more rapidly assess new treatments for ... are doing one plane."
For example, when imaging a joint like the knee
- Block's inspiration for developing the new technique - suppressing the ...
Rice bioengineers pioneer techniques for knee repair
... state-of-the-art clinical option for repairing small defects in articular knee
His lab is also working on techniques to grow replacement knee
menisci, the kidney shaped wedges of cartilage that sit between the femur ...
Antibacterial coatings cut infection rates
... Putting antibacterial coatings on hip and knee
implants and biomedical devices such as catheters could cut infection ... of South Australia have found.
A significant number of hip and knee
implants are prone to infection after surgery and in many cases are not ...
Arthritis: What Wnt wrong?
... of Medicine, examined joint tissue from patients who underwent total knee
replacement for rheumatoid arthritis (RA), osteoarthritis (OA), or ... and -10a as genes that were significantly upregulated in the arthritic knee
tissues. However, protein expression studies revealed that only Wnt-7b was ...