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The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life
...it possible to make three-dimensional films of the inner workings of living organisms at a much higher level of detail than ever before. One innovation of SPIM is the illumination of a sample from the side rather than along the traditional view of the microscope lens. This eliminates a problem that has pl...Poplar trees redirect resources in response to simulated attack
... as we've learned to use radiotracers to image the inner workings of the living human brain, we can now track biochemical and physiological processes within plants using these powerful imaging tools," said Richard Ferrieri, who leads Brookhaven's role in the research. "This enables us to study the effects ...Purdue proves concept of using nano-materials for drug discovery
... a protein, was placed inside the vessels - on the inner surface of the alumina membranes - and the liquid was placed outside each vessel so that it covered the opposite side of the membranes. When the liquid diffused through the membrane's pores, it mixed with the enzyme, causing a reaction and turning bl...Nano-Probes Allow an Inside Look at Cell Nuclei
...fancy, but biologists may soon use it to watch the inner workings of a living cell like never before. Scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and Lawrence Livermore National Laboratory have developed a way to sneak nano-sized probes inside cell nuc...Zebrafish may hold key to understanding human nerve cell development
...precursors -- the specialized neurons found in the inner earof humans that make hearing possible. This rese...er, in humans hair cells areburied deep inside the inner ear making them difficult to access. Haircells in zebrafish are located on the surface of their body...Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined
...precursors -- the specialized neurons found in the inner earof humans that make hearing possible. This rese...er, in humans hair cells areburied deep inside the inner ear making them difficult to access. Haircells in zebrafish are located on the surface of their body......precursors -- the specialized neurons found in the inner earof humans that make hearing possible. This rese...er, in humans hair cells areburied deep inside the inner ear making them difficult to access. Haircells in zebrafish are located on the surface of their body...Scientists discover that host cell lipids facilitate bacterial movement
...ntracellular pathogen can harness signals from the inner rather than the outer surface of the cell membrane. "The most exciting and surprising finding is that an intracellular bacteria is able to attract host cell membrane lipids to its surface and these membrane lipids facilitate the ability of the bacte...Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries
...ttacks in some people. Fatty buildups occur on the inner lining of an artery and gradually thicken into a plaque. As plaque grows, it narrows the artery more and more. When the plaque ruptures, blood clots form that can block the artery entirely. Low-density lipoprotein is transported inside arteries by m...Cerebral navigation: How do nerve fibers know what direction to grow in?
... a mystery. "Very little has been known about the inner workings of the cell that govern axon guidance," says Michael Greenberg, PhD, Director of the Neurobiology Program at Children's and senior author on both studies. "These studies begin to give insight into how the various steps of axon guidance are c...NIH Researchers Discover How Insulin Allows Entry of Glucose Into Cells
...cles immediately stop moving, tether to the cell’s inner surface, then fuse with the cell membrane. GLUT 4, contained in the vesicles?membrane, then enters the cell membrane, where it ferries glucose into the cell. The researchers made their observations using a technique known as total internal reflector...NIAID begins clinical trial of West Nile virus vaccine
... When the vaccine is injected into the muscle, the inner machinery of the muscle cells "reads" the DNA and converts it into two WNV proteins. Recognizing that the proteins are foreign, the muscle cells display them on their surface to alert the body's immune system--both helper T cells, which spur the prod...Study reveals dramatic difference between breast cancers in US and Africa
...ly to arise from basal-like cells, rather than the inner milk-secreting luminal cells, which are the most common source of breast cancers for U.S. and European women. (This type of basal-like breast cancer is also observed among women with inherited BRCA1 mutations). Tumors that arise from basal cells have...Scientists generate patient-specific stem cells, Science study says
...development. Stem cells were then derived from the inner cell mass of the blastocyst. In laboratory culture, these cell lines displayed signs of immunological compatibility with the patients' cells, Science authors reported. Oocyte donors and patients who donated non-reproductive cells were all unpaid vol...SuperLigands - a database of ligand structures derived from the Protein Data Bank
...development. Stem cells were then derived from the inner cell mass of the blastocyst. In laboratory culture, these cell lines displayed signs of immunological compatibility with the patients' cells, Science authors reported. Oocyte donors and patients who donated non-reproductive cells were all unpaid vol...Embryonic Stem Cells Treated With Growth Factor Reverse Hemophilia In Mice: UNC Researchers
...oderm precursors," or PEPs. Endoderm refers to the inner layer of early embryonic cells that develops into the digestive and respiratory systems. "Not only do ES cells differentiate into PEPs, they also engraft, persist, differentiate further and then function following injection, resulting in the persist...Engineers improve plastic's potential for use in implants by linking it to biological material
...tides to a container with polypyrrole stuck on its inner surface. The bacteriophages that didn't wash away when exposed to conditions that hinder attachment were retested on a new polypyrrole-coated container, a process that was repeated four more times. The sticky peptide selected, known as T59, is a str...Researchers Closer To Helping Hearing-Impaired Using Stem Cells
...of the nerve cells that are often missing from the inner ears of patients with profound hearing loss. “Sonic hedgehog and retinoic acid are molecules found in embryonic tissues, but not in adult tissues,?said Dr. Hashino. “This suggests that treating marrow-derived stem cells with these molecules before t...DNA constraints control structure of attached macromolecules
...ey envision building supramolecular machines whose inner workings are governed by twisted strands of DNA. In a paper that has been accepted for publication in the Journal of the American Chemical Society, and posted on its Web site, Silverman and graduate student Chandrasekhar Miduturu begin with a piece ...High fidelity keeps human DNA assembly line humming
...tate University have made a major discovery on the inner workings of genetic coding, mapping out mechanisms of one of life's most elemental functions: RNA synthesis. Their work has crucial implications for how a normal cell forms a tumor and how a virus runs amok. The work is published in the May 13 editi...UN successfully tests 'green' pesticide against locusts
...ey envision building supramolecular machines whose inner workings are governed by twisted strands of DNA. In a paper that has been accepted for publication in the Journal of the American Chemical Society, and posted on its Web site, Silverman and graduate student Chandrasekhar Miduturu begin with a piece ...Health costs soar as 60 million Americans classed as obese
...ey envision building supramolecular machines whose inner workings are governed by twisted strands of DNA. In a paper that has been accepted for publication in the Journal of the American Chemical Society, and posted on its Web site, Silverman and graduate student Chandrasekhar Miduturu begin with a piece ...Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed
...at the exterior of our bodies is symmetrical while inner organs are arranged asymmetrically. In research with zebra fish, as a model for human biology, Juan-Carlos Belmonte and his Salk Institute colleagues found that retinoic acid (vitamin A) is the signal that buffers the influence of asymmetric cues in...MIT engineers an anti-cancer smart bomb
... the nanocell with an anti-angiogenic drug and the inner balloon with chemotherapy agents. A "stealth" surface chemistry allows the nanocells to evade the immune system, while their size (200 nanometers) makes them preferentially taken into the tumor. They are small enough to pass through tumor vessels, bu...ORNL, UC Berkeley unravel real-world clues to Earth's mysteries
...the complex biological relationships and how these inner workings might apply on a grander scale. In a paper to appear today on Science Online, researchers from the Department of Energy's Oak Ridge National Laboratory and the University of California Berkeley describe a bacterial community that flourishes...Beyond genes: Lipid helps cell wall protein fold into proper shape
...layers sandwiching an impermeable water-unfriendly inner layer that defines the outer surface of cells. Transport of nutrients and waste material across the cell membrane is then governed by the specific proteins associated with it. In a strain of E. coli lacking PE, the GabP protein misfolded, with two a...New Lab Research May Help Those Deafened By Immune System Attack
...of people each year, the immune system attacks the inner ear, home to the tiny, delicate structures that al...ents had antibodies against a protein found in the inner ear, called IESCA for inner-ear supporting cell antigen. This is a sign their immune systems recogni...Beauty queens urge girls not to sacrifice their bones
...le beauty is partly physical it is also made up of inner beauty that includes respecting one's health and behavior. Medical specialists from IOF noted that with Asia's aging population, it is expected that the burden of osteoporosis will increase dramatically if no preventive action is taken. Dr Khunying...'Sinkers' provide missing piece in deep-sea puzzle
...nd can be up to one meter (three feet) across. The inner filter is slightly more dense, and traps small particles that the animals eats. The larvacean constantly pumps water through both filters, which typically become clogged after about 24 hours of use. At this point the larvacean abandons its house and ...Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development
...pace station," said Young. "If you try to open the inner door before the pressures have equalized, you can tease it open a little bit but it keeps closing on you until there's enough pressure in the airlock to allow it to open all the way." Melikyan explained, "The pore is an unstable structure at that mo...Nanoscale method for investigating living systems
... of manipulation, imaging and understanding of the inner workings of cells. The specks are known as quantum dots or inorganic semiconductor nanocrystals. Measuring in millionths of a millimeter, these dots are so small that the addition or removal of electrons changes the properties of the dot. The team, ...How fish hear and make sounds at same time
...mammals. While humans hear with the cochlea of the inner ear, the midshipman uses the sacculus, a part of the ear that in humans detects acceleration or linear movement. Because the study indicates a relationship between the ear and the auditory and vocalization systems of the brain, it could help scienti...Color perception is not in the eye of the beholder: It's in the brain
...ed by Williams that maps out the topography of the inner eye in exquisite detail. The technology, known as adaptive optics, was originally used by astronomers in telescopes to compensate for the blurring of starlight caused by the atmosphere. Williams turned the technique from the heavens back toward the ...Purdue's gold nanorods brighten future for medical imaging
...or a wide range of biological imaging to study the inner workings of cells and molecules. Findings are detailed in a research paper that appeared online last week in Proceedings of the National Academy of Sciences. The paper was written by researchers in Purdue's Weldon School of Biomedical Engineering an...Researcher says flu responders can learn from 1918 epidemic
...spitals which traditionally serve the needs of the inner city begin to run out of beds? Do we think that p... factors are found in combination in the nation's inner cities, he said. "With the 1918 flu, though, the exact opposite happened," he said. "Those who tend...Anti-cancer drugs may hold promise for premature aging disorder
...arnesylation. Farnesylation tethers lamin A to the inner nuclear membrane. Once there, a second tag within ...hat progerin was becoming permanently stuck to the inner nuclear membrane. There, he suspected, it enmeshed other scaffolding proteins, preventing their prop...Scientists map one of biology's critical light-sensing structures
...a 30-year quest by biologists to drill down to the inner workings of how plants, fungi and bacteria use light to guide their development. It will likely spur a rush by scientists to capitalize on the new knowledge and may one day lead to such things as plants whose growth, flowering and death can be preci...Phenolic compounds may explain Mediterranean diet benefits
...y healthy. The functioning of the endothelium (the inner lining) of small blood vessels of the fingers (instead of "in the arms") of participants and the concentrations of certain components in blood serum, including nitric oxide, improved after the polyphenol-rich breakfast. "This is the first study that...USC researchers track down the stem cells that create feathers
...are distributed in a ring configuration around the inner wall of the vase-shaped feather follicle. This is different from hair stem cells, which are located in a bulge outside the follicle," explains Cheng-Ming Chuong, M.D., Ph.D., professor of pathology at the Keck School and principal investigator on thi...New technique helps researchers determine amino-acid charge
... able to probe the electrostatic properties of the inner lining of the ion-channel's pore, and, from there, they inferred the rotational angle of the pore-lining alpha-helices in the open state. In this case, researchers focused on the muscle nicotinic acetylcholine receptor, a membrane protein that media...Engineers discover why toucan beaks are models of lightweight strength
... "The beak is mostly air," said Meyers. "While the inner part of human bone also contains cancellous bone, we don't have the foam interconnections, which produce a much stronger structure with very little additional weight." Like a house covered by a shingled roof, the foam is covered with overlapping ker...Animal models show that anabolic steroids flip the adolescent brain's switch for aggression
...ed that the outward aggressiveness correlated with inner changes in the brain. When the drugged hamsters were hostile hosts, a part of their brains called the anterior hypothalamus pumped out more of a neurotransmitter called vasopressin. By three weeks of withdrawal, vasopressin levels subsided in paral...Frog’s ear canal may provide insights for understanding human hearing loss
... in order to transmit ultrasonic vibrations to the inner ear. The presence of an ear canal not only protect...o lessens the distance between the eardrum and the inner ear, thus allowing the bones of the middle ear to be shorter, and as a result, lighter in weight. S...UW scientists unravel critical genetic puzzle for flu virus replication
...next. But while much is known about the genes and inner workings of flu viruses, how the microbe organizes its genetic contents to seed future generations of viruses has remained an enduring mystery of biology. Now, with the help of a long-studied flu virus, an electron microscope and a novel idea of how...Satellites show Amazon parks, indigenous reserves stop forest clearing
...greater than 1.5 percent outside their borders had inner deforestation rates of 0.75 percent or less. Few parks are located in active frontier areas (4 of 15 in the sample) than indigenous lands (33 of 38). But parks' and indigenous lands' ability to inhibit deforestation appear similar. Indigenous lands...'Nano-keys' bind cell receptors and trigger allergic reactions
... attach to the surface. This activates the cell's inner machinery. Said Baird: "In this way, we can control what the cell sees. The cells are binding to the engineered surfaces and getting turned on. We can then see how the cell is organizing itself due to the stimulus." Collaborators include: David Hol...Researchers solve mystery of how nuclear pores duplicate before cell division
...les such as RNA and protein in and out of a cell's inner sanctum, the nucleus, which safeguards the cell's genomic brain. All chemical reactions that occur in a cell emanate from the genes within the nucleus. "Maybe not surprisingly, any disturbance in the flow of information across the nuclear membrane ca...Protein 'nanosprings' most resilient found in nature
... in association with specialized hair cells of the inner ear, where they play a critical role in converting sound (a mechanical stimulus) into an electrical signal that can be transmitted to the brain ?a process known as mechanotransduction. Ankyrin proteins also coordinate the ion channels and transporte......ally open a new window into its largely mysterious inner workings. Howard Hughes Medical Institute investigator David E. Clapham and his colleagues published their findings in the February 9, 2006, issue of the journal Nature. Lead author on the paper was Yuriy Kirichok and the other co-author was Bets...UF scientists trace origin of shark's electric sense
...nically sense their environment, and organs of the inner ear that enable people to keep their balance. But scientists suspect as human ancestors emerged from the sea, they discarded their lateral lines as well as their ability to sense electrical fields. "Our fishy ancestors had the anatomy for it," said ...Yale researchers find environmental toxins disruptive to hearing in mammals
...sed profound changes in sound amplification in the inner ear. In his previous study using TBT on isolated cells only, Santos-Sacchi had proposed that the ear's ability to perceive sound would be compromised. He also speculated that whales and other marine mammals exposed to TBT would have altered sound lo...Anemone genes reveal versatile building blocks for body plans
...omponents deployed exclusively in the endoderm, or inner germ layer. It therefore appears that the ancient, ancestral function for this signaling system may have been to determine the different germ layers of the developing embryo in animals that lacked a bilateral body plan. Over evolutionary time, the ...Inside rocks, implications for finding life on Mars
...e technique, first used by biologists to study the inner workings of living cells, is new to geology. The ancient microorganisms are "pond scum," among the earliest life, much too small to be seen with the naked eye. Schopf's UCLA co-authors include geology graduate students Abhishek Tripathi and Andrew ...'Prosthetic' retinal cells let blind mice see light
...eatable by using the technique. "The remodeling of inner retinal neurons triggered by photoreceptor degeneration has raised some concerns for the retinal-based rescue strategy after the death of photoreceptors," wrote Pan and colleagues. "However, retinal degenerative diseases are heterogeneous as to the t...Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers
...urified from normal colon tissue. This epithelial inner lining of the colon contains about 50 million test-tube shaped crypts that line the colon. Colon cancer arises in these crypts, and researchers believe that the cells of origin are the 10-20 immortal stem cells that reside at the bottom of each crypt...AIDS-related cognitive impairment exists in two separate forms
...urified from normal colon tissue. This epithelial inner lining of the colon contains about 50 million test-tube shaped crypts that line the colon. Colon cancer arises in these crypts, and researchers believe that the cells of origin are the 10-20 immortal stem cells that reside at the bottom of each crypt......cal methods have allowed scientists to examine the inner life of the cell, an organisational unit basic to all life. Now, they are clarifying its structures in detail: from mitochondria, the "factories" of cells, which create energy; to the endoplasmic reticulum, necessary for protein synthesis and metabol...Bones hold the key to blood renewal
...n special 'stem cell niches' nestled in the bones' inner walls. Inside these sheltered nurseries, the stem ... bloodstream to assist in repairing damage. The inner walls of the bones are also sites of intensive reconstruction. While one type of cell, the osteoblas...With few factors, adult cells take on character of embryonic stem cells
...e tissue. Embryonic stem cells are derived from inner cells of the mammalian blastocyst, a ball of cells that develops after fertilization and goes on to form a developing embryo. Cells from other parts of the body can also be "reprogrammed" by transferring their nuclear contents into egg cell precursor...Computational model simulates AZT metabolism in mitochondria
...orm of AZT can enter the mitochondrial matrix, the inner core of the mitochondrion, and disrupt the replication of mitochondrial DNA by prematurely terminating DNA synthesis. Samuels added: "We're just starting our work. It is too early to say what the mechanism of mitochondrial toxicity of AZT is. The i...Other ContentsfetalfetalfetalfetalfetalfetalfetalfetalfetalfibromyalgiafibromyalgiadysplasiadysplasiadysplasiafibrousfibrousfibrousfibrousfibrousfibrousbreastbreastbreastbreastbreastbreastbreastbreastbreastbreastfibrocysticfibrinfibrinfibrinfibrinfissureOther TagsSelectiveSelectiveErectileProcedureProcedureApplicationApplicationApplicationApplicationApplicationSunshineCustomCustomCustomCustom
(Date:1/7/2009)...bridge, MA January 7, 2009 Phylonix Pharmaceuti...d a $1,250,369 Phase II Small Business Innovation ...of General Medical Sciences of the National Instit...assays for assessing drug effects on Cytochrome (C... development, is required by the Food and Drug Adm...
(Date:1/6/2009)...MIER INTERNATIONAL MEETING HIGHLIGHTS BREAKTHROUGH...IC DIFFERENCES,CAREFREE, AZ,FEBRUARY 3-6, 2009 ,...ces in treatment and outcomes among cancer patient...nderlying causes and what can be done to solve a s...tion for Cancer Research is hosting a collaboratio...
(Date:1/6/2009)...timore, MDStem cells are the body,s primal cells, ...e specialized types of cells over many cycles of c... Carnegie Institution have identified a gene, name...ing a variety of stem cells in their undifferentia...heir potency has implications both for our knowled...
(Date:1/6/2009)...rosaurs have long suffered an identity crisis. Po...inct flying lizards in with dinosaurs. Even paleon... they were birdlike in many ways, such as using on...is believed to be first-time evidence that launchi...equired pterosaurs to use four limbs: two were ult...
Breaking Biology News(10 mins):NIH grants Phylonix Phase II SBIR to develop high-throughput in vivo zebrafish assays 2American Association for Cancer Research hosts Science of Health Care Disparities Meeting 2'Scrawny' gene keeps stem cells healthy 2Four, three, two, one . . . pterosaurs have lift off 2Berkshire Medical Center Selects Desktop Alert for Mass Notification Solutions 32134 1Berkshire Medical Center Selects Desktop Alert for Mass Notification Solutions 32134 2Berkshire Medical Center Selects Desktop Alert for Mass Notification Solutions 32134 3Berkshire Medical Center Selects Desktop Alert for Mass Notification Solutions 32134 4Data mining of inpatient records reveals the disease pattern of obstructive sleep apnea 32131 1Data mining of inpatient records reveals the disease pattern of obstructive sleep apnea 32131 2Red Herring Awards ProGenTech Limited for the 2008 Red Herring Asia 100 9650 1Red Herring Awards ProGenTech Limited for the 2008 Red Herring Asia 100 9650 2Exciting discovery could stop cancer from killing people 32129 1(Date:1/7/2009)...Services of America,Inc. announced the formation o...n oncology joint venture. ROSA of South Alabama i... Gulf Shores, P.C., Monroeville Radiation -,Oncolo...C., and ASA,s,subsidiary, Radiation Oncology Servi...wn and operate four radiation oncology facilities ...
(Date:1/7/2009)...ement by Lois Aronstein, AARP NY State Director: ,...dress put forth recommendations on a number of iss...ncial security of New Yorkers of all ages. , , AA...he Family Health Plus Program to 200 percent of th...additional New Yorkers eligible for coverage. A f...
(Date:1/7/2009)... and the brain disease , , WEDNESDAY, Jan.... nine genes that might make people more likely to ...onfirmed earlier reports that a variation in the v...lso increase risk for Alzheimer,s. Low levels of ...,s and other dementias, leading researchers to sus...
(Date:1/7/2009)...ates in Northeast, government reports , , ...th rate in the United States increased in 26 of th...ion of the country, according to a new government ... for Disease Control and Prevention reported that ...eased for the first time in 15 years in 2006 -- fr...
Breaking Medicine News(10 mins):Health News:Ambulatory Services of America, Inc. Announces Joint Venture with Gulf Coast Cancer Centers 2Health News:9 Genes Are Linked to Alzheimer's 2Health News:Teen Birth Rate Up in 26 States in 2006 2SelectiveRacingErectileMummyProcedureTrojanXylitolGalliumNotoriousAntiviralsApplicationSunshineCustomCellulosic
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