incomplete

Molecular biology fills gaps in knowledge of bat evolution

...ause of a limited fossil record and conflicting or incomplete theories about their origins and divergence. Now, a research team including University of California, Riverside Biology Professor Mark Springer, has published a paper in the Jan. 28 issue of the journal Science that uses molecular biology and the fo...

Another Look Finds Promising Proteomics Test is Not Biologically Plausible

...ts may come about from such procedural problems as incomplete randomization of samples, Baggerly says. The study raises a question that is broader than the effectiveness of the experimental ovarian cancer test, the researchers say. “Are we going to be able to measure what we want to measure??Baggerly asks. “Gi...

New species from old data

...ts may come about from such procedural problems as incomplete randomization of samples, Baggerly says. The study raises a question that is broader than the effectiveness of the experimental ovarian cancer test, the researchers say. “Are we going to be able to measure what we want to measure??Baggerly asks. “Gi...

Cracking the olfactory code in bees

...ts may come about from such procedural problems as incomplete randomization of samples, Baggerly says. The study raises a question that is broader than the effectiveness of the experimental ovarian cancer test, the researchers say. “Are we going to be able to measure what we want to measure??Baggerly asks. “Gi...

Signaling protein builds bigger, better bones in mice

...ts may come about from such procedural problems as incomplete randomization of samples, Baggerly says. The study raises a question that is broader than the effectiveness of the experimental ovarian cancer test, the researchers say. “Are we going to be able to measure what we want to measure??Baggerly asks. “Gi...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

... that inhibition of tankyrase 1will compensate for incomplete inhibition of telomerase. Consequently,this strategy would shorten the time period of drug treatment that isrequired for the onset of telomere crisis and reduce the potential riskof acquired drug resistance, " writes Dr. Seimiya.Hiroyuki Seimiya, Yuk...

GATA: a graphic alignment tool for comparative sequence analysis

... that inhibition of tankyrase 1will compensate for incomplete inhibition of telomerase. Consequently,this strategy would shorten the time period of drug treatment that isrequired for the onset of telomere crisis and reduce the potential riskof acquired drug resistance, " writes Dr. Seimiya.Hiroyuki Seimiya, Yuk...

Variation in women's X chromosomes may explain differences among individuals, between sexes

...eral dozen expressed genes that females lack. The incomplete nature of X inactivation, demonstrated in the new study, means that at least 15 percent of the X-linked genes, and their protein products, are present at characteristically higher, and often variable, levels in females compared to males. Moreover, t...

Study reveals new technique for fingerprinting environmental samples

...Human Genome Project research. In the early 1990s, incomplete fragments of human genes called Expressed Sequence Tags (ESTs) were used as diagnostic fingerprints for human tissues to determine their unique features and disease status. These information-rich data allowed researchers to forge ahead with studying ...

Scientists use manufacturing methods to reconstruct mastodon

...se be involved in studying a larger number of more incomplete specimens," said Fisher, who plans to continue studying the actual skeleton after the exhibit opens. "We have done some work on the tusks and teeth, to recover the kinds of information on health, reproductive history, diet and climate that are the fo...

Researchers find first evidence of venom system in extinct mammal

... and his research team found a 60 million year-old incomplete skull fossil that they now believe is the first evidence of an extinct mammal with a venom delivery apparatus. The research will be published June 23, 2005 in Nature. "Our discovery shows that mammals have been much more flexible in the evolution of...

New bioinformatics technique for systematically analyzing key regions in DNA that help control gene activity

... and is particularly suitable to build models from incomplete and uncertain data. It has been used in applications ranging from medical and financial data analysis to voice recognition and image processing. Applied to gene regulation, the approach was able to predict the location of regulatory sites for about o...

UF study first to quantify validity of DNA I.D. tool using marine snails

...escribed forms." In those cases where the data is incomplete because the collection of known species is small, scientists currently rely on threshold values to identify the likelihood of a particular specimen being a brand new species vs. being distantly related to an existing one, he said. Using their databa...

Study provides insight into cellular defenses against genetic mutation

...ugh the instructions, resulting in the building of incomplete proteins. Affected mRNAs create shortened, disabled proteins that can sabotage natural processes by competing for spots usually held by their full-length counterparts, or by simply not working. In recent years, researchers at the University of Roch...

Computer models aid understanding of antibody-dependent enhancement in spread of dengue fever

... who were previously infected and have partial but incomplete immunity to the virus. Enhanced virus replication triggers a more deadly, hemorrhagic form of the disease. A study published in the online edition of Proceedings of the National Academy of Sciences suggests that antibody-dependent enhancement offer...

Newly discovered birdlike dinosaur is oldest raptor ever found in South America

...overed on southern continents. Nevertheless, their incomplete preservation led to some ambiguity and debate regarding their identities. The new discovery provides definitive evidence that dromaeosaurs also lived in South America, which was part of Gondwana. As a result, dromaeosaurs must have originated when ...

Novel protein complex enables survival in hostile environment

...unts of oxygen with sulfide would have produced an incomplete oxidation product ?sulfite," he said. "Methanogens present during the oxygenation of earth had to face this sulfite." But Johnson and Mukhopadhyay could not find any sign of such ability in the DNA sequence data for methanogens. "It was clear that...

Researchers develop new method to help find deadly malaria parasite's Achilles heel

.... "All the protein networks described so far are incomplete and statistically noisy," said Ideker. "But whether they are incomplete and noisy in the same way or not, we can say with confidence that this particular stage of Plasmodiu...

Forgotten by evolution?

...here was no typical striped pattern; this suggests incomplete development of the contractile apparatus. In addition, the expression of marker genes for cardiomyocytes, like the alpha-myosin-heavy-chain protein, could only be shown after the scientists performed what is known as epigenetic reprogramming (epigene...

Gene needed for butterfly transformation also key for insects like grasshoppers

...lso is key for the maturation of insects that have incomplete metamorphosis. The work appears to present the fir...d gene appear in the development of insects having incomplete metamorphosis," said Riddiford. "It appears in the late embryonic stage and stays throughout nymphal...

Iraq's marshes show progress toward recovery

...shes had been reflooded by September 2005. Despite incomplete data, the researchers found that in many respects the restored marshes they studied are functioning at levels close to those in one marsh that remained undrained. The fast recovery of plant production, overall good water quality, and rapid restoratio...

Genetic tug of war determines sexual differentiation

...elop ovaries, while XX mice that lose Wnt4 develop incomplete testes. This suggests that vertebrate sex determination results from the interplay between these two opposing signals." The researchers published their findings in the May 22, 2006, issue of the journal Public Library of Science-Biology. Their resea...

Bird flu study highlights need to vaccinate flocks effectively

...ed in Nature journal, is the first to quantify how incomplete vaccination of flocks can contribute to the undetected spread of the disease. Vaccination of commercial poultry against highly pathogenic avian flu like H5N1 is proving controversial because it is thought that it can lead to unseen transmission bet...

Massive duplication of genes may solve Darwin's 'abominable mystery' about flowering plants

... By developing new statistical methods to analyze incomplete DNA sequences from thirteen strategically selected plant species, the researchers uncovered a previously hidden "paleopolyploidy" event, an ancient whole-genome duplication that preceded the appearance of the ancestral flowering plant. The results w...

Reversing 'hibernating' heart muscle focus of UB researchers

... "Identifying the basic mechanisms responsible for incomplete functional recovery after revascularization hopefully will lead to new therapies that will improve the outlook and symptoms of these patients who are at high risk for adverse cardiovascular events," said Canty. Additional investigators on the study...

Where we change our mind

... adept at adapting. It can make decisions based on incomplete information and update those decisions based on new information. The nature of such sophisticated decision making in the cerebral cortex, which is responsible for high-level processing, has been "poorly studied and little understood," according to W...

Pharmaceutical compounds found in nation's fresh water

...ic tanks and, consequentially, ground water due to incomplete human metabolism and excretion into the waste stream or by disposal of unused medications in the toilet or down the sink. This screening-level study investigated the occurrence of pharmaceuticals in areas receiving waste water from septic tanks loc...

40,000-year-old skull shows both modern human and Neandertal traits

... be the result of evolutionary reversal or reflect incomplete palaeontological sampling of Middle Paleolithic human diversity. "They could also reflect admixture with Neandertal populations as modern humans spread through western Eurasia. This mixture would have resulted in both archaic traits retained from ...

Robotic exoskeleton replaces muscle work

...his could benefit stroke patients or patients with incomplete injuries of the spinal cord," said Daniel Ferris, associate professor in movement science at U-M. "For patients that can walk slowly, a brace like this may help them walk faster and more effectively." Ferris and former U-M doctoral student Keith...

Beyond the DNA: Chemical signatures reveal genetic switches in the genome

...alone, but these are inadequate because we have an incomplete understanding of the sequence features that identify enhancers. The elucidation of a common histone modification signature will enable scientists to quickly identify enhancers and promoters for a gene, which will lead in turn to rapid identification ...

World's leading scientists announce creation of 'Encyclopedia of Life'

... Noting that "our knowledge of biodiversity is so incomplete that we are at risk of losing a great deal of it before it is ever discovered," Wilson called for a contemporary, dynamic portrait of the living Earth. "I wish that we will work together to help create the key tool that we need to inspire preserva...

Researchers use MRI to predict recovery after spinal cord injury

...ete motor and sensory SCI was seen in 26 patients, incomplete SCI was seen in 51 patients, and 22 patients were neurologically intact upon admission. One patient could not be classified. The majority of the patients had been injured in motor vehicle accidents. MRI exams were obtained within 24 to 48 hours of...