Hypothalamic in Biological News

How appetite-stimulating brain cells work overtime during fasting

... UCP2, which is present at high levels in the hypothalamic arcuate nucleus--considered to be the key brain ... hypothalamus that fat levels have fallen, leading hypothalamic neurons to activate a program, including hunger, ... and colleagues] have elegantly demonstrated that hypothalamic responses to food deprivation involve at least ...

Hap1 protein links circulating insulin to brain circuits that regulate feeding behavior in mice

... how Hap1 is linked to feeding-related molecules such as insulin, and to hypothalamic neuronal function," said Xiao-Jiang Li, PhD, professor of human genetics ... "Scientists know that diabetes and obesity are related to abnormalities of hypothalamic function," Li said. "This is a complicated pathway, and Hap1 can help us ...

Study by Einstein researchers could lead to a novel strategy for treating obesity

... a molecule suspected of being one of the critical nutrients influencing hypothalamic regulation of eating behavior. Previous studies had shown that hypothalamic levels of malonyl CoA increase markedly after meals and are suppressed by ...

Slipping past the blood brain barrier: Research shows potential treatment for brain cancer

... of the research team. The compound - JV-1-36 - is an antagonist of the hypothalamic growth hormone- releasing hormone, which has been found to cause cancerous ... such as malignant glioblastomas, to grow. The main known purposes of the hypothalamic growth hormone-releasing hormone usually are to trigger the hormone that ...

Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress

... by the hypothalamus, such as feeding. Di says that the "actions of the endocannabinoids on the synaptic circuits that control the activity of the hypothalamic neurons serve to rapidly inhibit hormone secretion from the pituitary gland, providing a rapid negative feedback mechanism for the regulation of ...