hypothalamic

Endocannabinoids ?the brain's cannabis ?demonstrate novel modes of action to stress

...synaptic circuits that control the activity of the hypothalamic neurons serve to rapidly inhibit hormone secretion from the pituitary gland, providing a rapid negative feedback mechanism for the regulation of neuroendocrine function during stress." Japanese team finds inhibition of excitatory and inhibitory syna...

Slipping past the blood brain barrier: Research shows potential treatment for brain cancer

... The compound - JV-1-36 - is an antagonist of the hypothalamic growth hormone- releasing hormone, which has been ...blastomas, to grow. The main known purposes of the hypothalamic growth hormone-releasing hormone usually are to trigger the hormone that makes children grow and aff...

Study by Einstein researchers could lead to a novel strategy for treating obesity

...of being one of the critical nutrients influencing hypothalamic regulation of eating behavior. Previous studies had shown that hypothalamic levels of malonyl CoA increase markedly after meals and are suppressed by fasting. The Einstein re...

Hap1 protein links circulating insulin to brain circuits that regulate feeding behavior in mice

... feeding-related molecules such as insulin, and to hypothalamic neuronal function," said Xiao-Jiang Li, PhD, profe...abetes and obesity are related to abnormalities of hypothalamic function," Li said. "This is a complicated pathway, and Hap1 can help us explain it and hopefully m...

How appetite-stimulating brain cells work overtime during fasting

...tein, UCP2, which is present at high levels in the hypothalamic arcuate nucleus--considered to be the key brain si... hypothalamus that fat levels have fallen, leading hypothalamic neurons to activate a program, including hunger, to preserve energy and restore fat levels, he said....