Herpesvirus in Biological News

Herpes virus: To vaccinate or not to vaccinate

... infection with bacterial pathogens. Although herpesvirus infections are generally considered undesirable ... infections: "We discovered that the effect of herpesvirus infection is transient, lasting only a few ... research for the development of vaccines against herpesvirus infections. Dr. Virgin suggested that "decreased ...

Tips from the Journals of the American Society for Microbiology

... herpesvirus May Play Role in Central Nervous System Diseases ... Scientists have discovered evidence suggesting a herpesvirus may be responsible for some cases of meningitis ... of the Journal of Clinical Microbiology. Human herpesvirus 6 (HHV-6) is one of the most prevalent in humans. ...

UC Berkeley virologist named Keck Distinguished Young Scholar

... five years, will go to UC Berkeley to support Glaunsinger's work using the herpesvirus as a tool to study the inner workings of human cells. The foundation ... Glaunsinger will use the grant money for innovative experiments using the herpesvirus to probe how our cells regulate their RNA. The virus uses a mysterious ...

Research uncovers clues to virus-cancer link

... , Dirk Dittmer, Ph.D. associate professor of microbiology and immunology at UNC's School of Medicine, demonstrated that the Kaposi sarcoma associated herpesvirus (KSHV) is not only present in every tumor cell, but that the cells also transcribe microRNAs (miRNA) from the virus. This represents a collaborative ...

Algorithm finds the network -- for genes or the Internet

... in are diverse, ranging from stress responses and virus infection in plants, such as rice, to human diseases, including Alzheimer's disease, herpesvirus infection, sepsis, cardiac hypertrophy, lung cancer and lung transplantation. The computational tools his group has developed are helping him and ...

Study proposes new theory of how viruses may contribute to cancer

... The paradigm was developed based on a study of cells infected with the Kaposis sarcoma associated herpesvirus, or KSHV, also known as human herpesvirus 8 (HHV-8). The researchers examined a gene called K13 that activates a pathway previously implicated in cancer development. Cells with low K13 ...

Virus may control Australia's

... Industries Victoria ?are investigating Koi herpesvirus as a means of controlling the introduced fish. ... project will investigate the effectiveness of Koi herpesvirus in controlling strains of carp present in ... organs and eventually killing its host. Koi herpesvirus is attractive as a biological control agent as ...

Association of herpesvirus with lung disorder questioned

... in Japan found no association between a herpesvirus infection and a potentially life-threatening form ... reported that they were not able to detect human herpesvirus 8 (HHV-8), also known as the Kaposi's sarcoma ... uncommon, Katano and co-authors explained. Human herpesvirus 8 infection is associated with Kaposi's sarcoma, ...

Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor

... human cell surface molecule involved in infection by Kaposi's sarcoma herpesvirus (KSHV), the virus that causes Kaposi's sarcoma and certain forms of ... "Understanding the mechanisms of cell entry of Kaposi's sarcoma herpesvirus is a landmark achievement in and of itself," says NIAID director Anthony ....

Finnish scientists discovered a new approach to treat virus-induced lymphomas

... Kaposi’s sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi’s sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with ...

An AIDS-related virus tricks cells to become tumors, new Penn study finds

... Researchers at the University of Pennsylvania School of Medicine have discovered how the Kaposi's sarcoma-associated herpesvirus (KSHV) subverts a normal cell process in order to promote tumor growth. The finding, published in the most recent issue of PLoS Pathogens, offers new ...

Failure of 'scout cells' may lead to cancer in transplant patients

... that normally serve as scouts for the immune system become weakened, a new study suggests. The cancer is caused by Epstein-Barr virus (EBV), a herpesvirus that infects more than 90 percent of Americans but is ordinarily kept under control by the immune system. That control can be lost in people whose ...

Mechanism for Epstein-Barr virus protein's role in blood cancers discovered

... as that, but it's a major mystery solved that many researchers have been working on for at least 15 years," says Robertson. EBV, a member of the herpesvirus family and one of the most common human viruses, plays a role in cancers such as lymphoproliferative diseases in transplant or AIDS patients, ...

Touching Molecules With Your Bare Hands

... protein—a potentially recognizable target for immune cells. Gamma-herpesviruses, including Epstein-Barr virus (EBV) and Kaposi’s sarcoma–associated herpesvirus (KSHV), can induce uncontrolled lymphocyte (immune cell) proliferation and result in lymphoma, Hodgkin’s disease, and Kaposi’s sarcoma. These ...

How A Latent Virus Eludes Immune Defenses

... protein—a potentially recognizable target for immune cells. Gamma-herpesviruses, including Epstein-Barr virus (EBV) and Kaposi’s sarcoma–associated herpesvirus (KSHV), can induce uncontrolled lymphocyte (immune cell) proliferation and result in lymphoma, Hodgkin’s disease, and Kaposi’s sarcoma. These ...

Defensins neutralize anthrax toxin

... ?the cell cycle of the usually quiescent human B cells gets a jump start, which ultimately initiates uncontrolled growth. EBV, a member of the herpesvirus family and one of the most common human viruses, plays a role in cancers such as lymphoproliferative diseases in transplant or AIDS patients, ...

Epstein-Barr virus protein crucial to its role in blood cancers

... ?the cell cycle of the usually quiescent human B cells gets a jump start, which ultimately initiates uncontrolled growth. EBV, a member of the herpesvirus family and one of the most common human viruses, plays a role in cancers such as lymphoproliferative diseases in transplant or AIDS patients, ...

How an AIDS-Related Cancer Unleashes Inflammation

... ?immune system proteins that trigger the cell's inflammatory response. A central question, he said, has been how does the Kaposi's sarcoma-associated herpesvirus that causes KS initiate cytokine production? "While there are many genes in the viral genome that are capable of inducing cytokine production, the ...