Hemorrhagic in Biological News

Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections

... development for the treatment of viral hemorrhagic fevers under a contract worth up to $44.4 million ... viruses--cytomegalovirus and Lassa fever virus, a hemorrhagic fever virus that is listed as a class A ... assessment of anti-PS antibodies to treat viral hemorrhagic fevers, research on the role of PS in viral ...

The Uukuniemi virus helps to explain the infection mechanism of bunyaviruses

... the infection mechanism of bunyaviruses causing hemorrhagic fevers and encephalitis A researcher group ... drugs for treating bunyavirus diseases, such as hemorrhagic fever and encephalitis. The findings were ... of the family cause serious disease, such as hemorrhagic fever and encephalitis, for which no vaccines are ...

Global warming linked to European viral epidemic

... themselves". PUUV is a hantavirus, a group of viruses known to cause hemorrhagic fevers (fevers combined with bleeding disorders). NE is a relatively mild hemorrhagic fever that causes flu-like symptoms often with renal complications, ...

Gene is likely cause of stroke-inducing vascular malformations

... connection produces enlarged, tangled masses of vessels that are prone to hemorrhagic rupture, bleeding and stroke. Because they develop most often in growing tissues, BAVMs are responsible for half of the hemorrhagic strokes in children. Study findings were published in a recent issue ...

Sticky protein helps reinforce fragile muscle membranes

... basal lamina muscle membrane interaction and compromises the integrity of the muscle membranes. LCMV is a member of a group of viruses that can cause hemorrhagic diseases. The study suggests that these viruses disrupt the dystroglycan basal lamina interaction, rendering the cell membrane susceptible to ....

Songs raise awareness about aquatic invasive species

... minnows from one lake to another if water has already been added from the first lake to the minnow bucket, which prevents VHS fish disease (viral hemorrhagic septicemia) from spreading from an infected to a noninfected lake. Natural resource professionals reviewed the lyrics of each song to assure ...

Statins may treat blood vessel disorder that can lead to fatal strokes

... of lives a year, University of Utah School of Medicine researchers have shown that a blood vessel disorder leading to unpredictable, sometimes fatal, hemorrhagic strokes, seizures, paralysis or other problems is treatable with the same statin drugs that millions of people take to control high cholesterol. ...

Yale researchers unravel mystery of brain aneurysms

... of developing this deadly problem. These genetic findings provide a starting point for changing that equation," Gunel said. The median age when hemorrhagic stroke occurs is 50 years old, and usually there are no warning signs. In the majority of cases, the resulting strokes cause death or severe brain ...

Scientists uncover Ebola cell-invasion strategy

... virus infects cells a critical step to finding a way to treat the deadly disease produced by the virus. Ebola produces severe and often fatal hemorrhagic fever in its victims and inflicts mortality rates close to 90 percent in some outbreaks. No vaccine or antiviral therapy has been developed against ...

Tips from the Journals of the American Society for Microbiology

... infections worldwide. Tropical regions are at especially high risk where illness may range from mild symptoms to potentially fatal forms of dengue hemorrhagic fever and dengue shock syndrome. With all four strains of the virus sharing similar clinical presentation, epidemiology, and distribution, ...

Scripps research scientists reveal key structure from ebola virus

... critical piece of the virus is assembled and, importantly, identifies vulnerable sites that we can exploit." There is currently no cure for Ebola hemorrhagic fever. The virus is spread when people come into contact with the bodily fluids of someone who is already infected. Most ultimately die from a ...

New ballast treatment could protect Great Lakes fish

... a simple way to treat ballast water in vessels ranging from pleasure craft to ore boats. His method is designed to kill the virus that causes viral hemorrhagic septicemia (VHS), an often-fatal disease that has been attacking fish populations in the lower Great Lakes. Hand's treatment is simple. The ...

Scientists to explore global change-public health connection

... Dynamics of Infectious Diseases Duane Gubler, University of Hawaii: The 20th Century Emergence and Spread of Epidemic Dengue/Dengue hemorrhagic Fever: Is Climate or Environmental Change Responsible? Stephen Hoffamn, Sanaria, Inc.: Malaria The interplay between science, policy, and ...

Ayurvedic nightshade deadly for dengue mosquito

... use. Around two-fifths of the Worlds population is at risk from dengue fever, which is characterized by a high fever, pain and rashes. Dengue hemorrhagic fever is a potentially lethal complication, affecting mainly children. ...

APS names 2 minority outreach fellows

... Health Sciences Center. Her research focuses on the cardiovascular, neuroendocrine, and immune impact of alcohol on the outcome from trauma and hemorrhagic shock. Mathis plans to continue her research and career by first becoming a post-doc, then by establishing a laboratory of her own. Mathis long-term ...

Ebola virus disarmed by excising a single gene

... is a great system." The Ebola virus first emerged in 1976 with outbreaks in Sudan and Zaire. There are several strains of the virus, which causes hemorrhagic fever and during outbreaks kills anywhere from 50-90 percent of its human victims. At present, research on live Ebola virus is confined to the ...

NIH awards UC $9 million grant to improve patient point-of-care technologies

... has tried over-the-counter medications to no avail and is now experiencing nausea and visual impairment. Is it sinusitis" Migraine" Or perhaps a hemorrhagic stroke" Current technology takes hours to indicate the source of the problem. The improved point-of-care technologies could take a matter of one or ...

Discovery could lead to better control of hemorrhagic fever viruses

... through which a group of life-threatening hemorrhagic fever viruses enter and attack the body's cells, ... Bolivian, Venezuelan, Argentine and Brazilian hemorrhagic fever, respectively, with mortality rates of ... sped up the work. Although not all hemorrhagic fever viruses use TfR1 to enter the body's cells, ...

'GreeneChip' -- New diagnostic tool that rapidly and accurately identifies multiple pathogens

... failed to implicate a microorganism in a fatal hemorrhagic fever case is described in the January 2007 issue ... obtained from patients with respiratory disease, hemorrhagic fever, tuberculosis, and urinary tract ... of an unknown sample from a patient with a viral hemorrhagic fever (VHF)-like syndrome. Within six to eight ...

Researchers discover key mechanism by which lethal viruses Ebola and Marburg cause disease

... in Latin), are associated with outbreaks of fatal hemorrhagic fever in sub-Saharan Africa. Viral hemorrhagic fevers are of specific concern because they are ... human-to-human transmission. The term "viral hemorrhagic fever" characterizes a severe multisystem ...

Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses

... as serious, causing tick-borne encephalitis or hemorrhagic fevers. Currently, a Japanese encephalitis ... encephalitis lead to inflammation of the brain. hemorrhagic fevers are viral infections that cause ... as the more serious tick-borne encephalitis, Omsk hemorrhagic fever (found in western Siberia) and the closely ...

Fragment of yellow fever virus may hold key to safer vaccine

... These days, the horror of Ebola or Marburg hemorrhagic fever grabs more attention, but yellow fever is the original viral hemorrhagic fever. It strikes more than 200,000 people a ... health authorities, ter Meulen set up a viral hemorrhagic fever laboratory in Conakry to collect and ...

Scientists discover how Ebola virus infects cells

... of viruses that cause severe and frequently fatal hemorrhagic fevers. "Finding medical countermeasures for viral hemorrhagic fevers is a global public health priority because ... therapy that could be effective against multiple hemorrhagic fever viruses." Senior author James M. ...

Researchers discover molecule that causes secondary stroke

... 10 days following a massive brain bleed known as hemorrhagic stroke. Sixty percent of patients who survive the ... blood-brain barrier," Dr. Clark says. "After a hemorrhagic stroke, however, toxins given off by the brain ... but also a diagnostic test to determine which hemorrhagic stroke survivors are at greater risk." Several ...

New study may show how to forestall a fatal, virus-caused immune-system meltdown

... infected by the much more dangerous Lassa virus, which can cause an acute hemorrhagic fever and kills about 5,000 people a year in West Africa. (During some ... like Lassa fever. “Early on, you can’t really differentiate these nasty hemorrhagic fever viruses from their symptoms ?they just resemble the flu,?Herzog ....

Tulane researcher reports on origin of deadly fever outbreak

... may have been responsible for the deadly 1998?000 outbreak of Marburg hemorrhagic fever among gold miners in the Democratic Republic of the Congo, according ... fever may have been spread directly to humans by the host animals. Marburg hemorrhagic fever, a severe filovirus-caused disease related to Ebola, was first ...

Hantavirus found in African wood mouse

... in Central and Eastern Europe." European and Asian hantaviruses cause hemorrhagic fever with renal syndrome (HFRS), a group of similar illnesses with ... of Ecology and Evolution, Moscow; and Lamine Koivogui of the Viral hemorrhagic Fever Project, Conakry, Guinea. ...

Cord blood cells may widen treatment window for stroke

... often lack ready access to a CT scan, a test needed to rule out a hemorrhagic stroke caused by a burst blood vessel. The drug can worsen this less ... alleviating, even eliminating, the disabling effects of both ischemic and hemorrhagic stroke. What's more, the treatment can be delivered much later than the ...

Clot-dissolving agent may be beneficial in treatment of severe frostbite

... the authors write. “Candidates for this therapy are patients who present with severe frostbite as suggested by full-thickness tissue involvement, hemorrhagic blisters and abnormal perfusion on either angiogram or pyrophosphate scanning. Initiation of therapy within 24 hours of rewarming also appears to be ...

Cornell lab confirms deadly fish virus spreading to new species

... epidemic proportions, according to Paul Bowser, Cornell professor of aquatic animal medicine in the College of Veterinary Medicine. The viral hemorrhagic septicemia virus (VHSV), which causes anemia and hemorrhaging in fish, has now been identified in 19 species and poses a potential threat to New ...

Pattern of human Ebola outbreaks linked to wildlife and climate

... the University of California, San Diego and her colleagues in Africa and Britain have shown that there are close linkages between outbreaks of Ebola hemorrhagic fever in human and wildlife populations, and that climate may influence the spread of the disease. The decade-long study, published this month ...

Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack

... fatality rate of about 30 percent), modified (which occurs in people who have been vaccinated and has a death rate of about 10 percent), and flat and hemorrhagic (both very rare and uniformly fatal). According to the CDC, exposure to the variola virus is followed by an incubation period of seven to 17 ...

Cornell researchers find serious fish virus in Northeast for first time

... Cornell University researchers. According to experts at the Aquatic Animal Health Program at Cornell's College of Veterinary Medicine, the viral hemorrhagic septicemia virus (VHSV), which causes fatal anemia and hemorrhaging in many fish species, was discovered in upstate New York. It poses no threat to ...

Fish virus in Northeast spreading to other fish species

... Ontario and the St. Lawrence River. Last week, an estimated 1,000 dead fish washed up on the shores of Lake Ontario in just one morning. Viral hemorrhagic septicemia virus (VHSV) was detected and confirmed for the first time in the Northeast in round gobies and muskellunge in June. Cornell researchers ...

Gene-specific Ebola therapies protect non-human primates from lethal disease

... may be more potent than anti-virals such as protease inhibitors, which seek to inhibit a protein needed for viral replication. Ebola virus causes hemorrhagic fever with case fatality rates as high as 80 percent in humans. The virus, which is infectious by aerosol (although more commonly spread through ...

Ocean virus identified in human blood samples

... virus that causes gastroenteritis. Other caliciviruses cause a wide range of disease in other animal species. The Lagovirus genus causes a fatal hemorrhagic disease and hepatitis that has killed millions of rabbits across four continents in the past 20 years. In more than 30 years of research, part of ...

'Bad' enzymes may wear white hats after stroke

... disease. Statins are a class of drugs that reduce serum cholesterol levels. "I did some work suggesting that statins might counteract the hemorrhagic effect of tPA and might someday be used as an adjuvant therapy with tPA," she said. "I also did some work with beta amyloid, the protein implicated ...

Simple idea to dramatically improve dengue vaccinations

... exposure to one of the four ?either by prior infection or by vaccination ?makes people significantly more likely to develop a potentially lethal hemorrhagic infection if they are later infected by one of the other three viruses. "This is a classic case of something called 'original antigenic sin,' ...

Computer models aid understanding of antibody-dependent enhancement in spread of dengue fever

... in people who were previously infected and have partial but incomplete immunity to the virus. Enhanced virus replication triggers a more deadly, hemorrhagic form of the disease. A study published in the online edition of Proceedings of the National Academy of Sciences suggests that antibody-dependent ...