Genome in Biological News

Mystery E. coli genes essential for survival of many species

... at the University of Dundee has examined the genome sequence of this workhorse of the laboratory and ... identified through sequencing of the E. coli genome and studied them to discover their significance. ... in cell division. ygjD is present in the human genome and also appears to be the key player of the ...

Telomeres resemble DNA fragile sites

... own weakness. They resemble unstable parts of the genome called fragile sites where DNA replication can ... telomeres and common fragile sites, parts of the genome where breaks tend to occur, albeit infrequently. ... how common fragile sites break throughout the genome and why." ...

Exploring standards to advance microbial genomics

... to find that two-thirds of the nearly 5,000 genome projects reported in the Genomes OnLine Database ... with microbial genomics, according to DOE JGI genome Biology head Nikos Kyrpides, if researchers would ... Conference, Kyrpides calls for the development of genome annotation standards and their adoption by ...

AACR applauds nomination of Francis S. Collins, M.D., Ph.D., to be the new NIH director

... Research. "His leadership of the National Human genome Research Institute and the Human genome Project has demonstrated his talent for ... at the National Cancer Institute on The Cancer genome Atlas, an effort to understand the genetic basis ...

Springer to collaborate with the Human Genome Organization

... The HUGO Journal in cooperation with the Human genome Organisation (HUGO). Formerly published at ... clinical and population explorations of the human genome and genomes of organisms relevant to human ... President of HUGO and Executive Director of the genome Institute of Singapore. Peter Butler, ...

New national genome center launched

... A new UK national genome centre is being officially opened today (3 July) by Nobel Laureate and genome pioneer Prof Sir John Sulston and the Lord-Lieutenant of Norfolk. The genome Analysis Centre (TGAC) will further the UK's ...

Ben-Gurion U. researchers reveal connection between cancer and human evolution

... were recently the cover story in the journal genome Research . The team of researchers from BGU's ... Negev (NIBN) set out to look for mutations in the genome of the mitochondria, a part of every cell ... this hypothesis, the researchers analyzed the genome mitochondria mutations from 98 unrelated ...

CSHL scientists harness logic of 'Sudoku' math puzzle to vastly enhance genome-sequencing capability

... to revolutionize the fast-changing world of genome sequencing and the field of medical genetics, ... cover story in the July 1st issue of the journal genome Research . Combining a 2,000-year-old Chinese ... the DNA alphabet (A, T, G, and C) line up in the genome to be determined all at once. This ...

NIH expands Human Microbiome Project; funds sequencing centers and disease projects

... funding levels over four years are: Human genome Sequencing Center, Baylor College of Medicine, ... Ph.D.; $3.7 million Washington University genome Sequencing Center, Washington University School ... diseases. Julia Segre, Ph.D., National Human genome Research Institute, Bethesda, Md. Skin and nose: ...

Midget plant gets makeover

... Plant Biology, just released a new version of the genome sequence of this model plant, which includes an ... this critical research. The new TAIR9 genome release contains detailed information on all ... and we've made extensive updates to the genome sequence based on new sequence data submitted to ...

DNA template could explain evolutionary shifts

... hard about copy number variation with respect to genome evolution, gene evolution and exon shuffling," ... represents a newly discovered method by which the genome generates copy number variation among genes, but ... involves structural changes in the human genome that result in the deletion of genes or parts of ...

Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii

... (VBI) and Virginia Tech, have completed the genome sequence of Azotobacter vinelandii , uncovering ... The work of the Azotobacter vinelandii genome project team, which will be featured on the cover ... identifies unique features of the A. vinelandii genome that explain how the bacteria is involved in ...

Geography and history shape genetic differences in humans

... that natural selection may shape the human genome much more slowly than previously thought. Other ... the distribution of variants in parts of the genome that affect the structure and regulation of ... to the distribution of variants in parts of the genome that do not affect proteins. Since these neutral ...

DOE JGI releases expanded version of Phytozome.net

... by the U.S. Department of Energy (DOE) Joint genome Institute (JGI). Phytozome provides a central ... model plant Arabidopis thaliana and a reference genome shedding light on the genetics, physiology, ... but also as a key link in understanding plant genome evolution. Selaginella moellendorffii , a ...

Research team finds important role for junk DNA

... strands of genetic material that dominate the genome but seem to lack specific functions. Why would nature force the genome to carry so much excess baggage? Now ... and Indiana University who have been studying the genome of a pond organism have found that junk DNA may ...

Researchers gain genome-wide insights into patterns of the world's human population structures

... of Washington (UW) assistant professor of genome sciences. Akey is senior author of new genomic ... B. Scheinfeldt, both of the UW Department of genome Sciences. A statistical method called ... Oceania. This global sampling came from The Human genome Diversity Project - Center for the Study of Human ...

A genome may reduce your carbon footprint

... Madison, WI, May 11, 2009 -- With the costs of genome sequencing rapidly decreasing, and with the ... is increasingly being placed on ways to apply genome data to real world problems, including reducing ... were published in the current issue of The Plant genome . Acquiring the genetic component of natural ...

New early detection studies of lung cancer in non-smokers launched today

... Smokers (Principal Investigator (PI): Hanash) genome analysis: Mining the genome and Transcriptome in Lung Cancer from Never ... University School of Medicine, Baltimore, Md.) genome analysis: Genomic Studies of Lung Cancer Arising ...

Genome projects launched for three extreme-environment animals

... announced today the launch of three new genome projects that focus on animals living in extreme ... cost effective completion of several other large genome projects at BGI-Shenzhen, including the Panda and ... will be used here to construct complete genome sequences for each of these animals and to carry ...

DNA blueprint for healthier and more efficient cows

... from 25 countries involved in the six-year Bovine genome Sequencing Project designed to sequence, annotate and analyse the genome of a female Hereford cow called L1 Dominette. The scientists discovered that the bovine genome contains 2,870 billion DNA building blocks, ...

A genomic CluE for cloud computing

... allows faster gene sequence alignment and genome assembly. While parallel computing is already ... The massive amounts of data generated by just one genome may take a significant amount of time to transfer ... the sequencing process cannot handle a whole genome at once. The DNA strands have to be chopped into ...

Bovine genome provides clues to possible new developments

... developed an annotated sequence of the cattle genome which could lead to better disease resistance and ... was led by the Baylor College of Medicine Human genome Sequencing Center and published in two reports ... from a single Hereford cow and comparative genome sequences for six more breeds, looking for ...

Sequencing the cow's genetic code -- a new agricultural era dawns

... cow named L1 Dominette. Sequencing the bovine genome is now complete, paving the way for research into ... the needs of an increasing world population. The genome provides a major novel resource to study not only ... less greenhouse gas emissions. "The bovine genome is more similar to that of humans than mice or ...

Major international study challenges notions of how genes are controlled in mammals

... scientific community with extensive data on the genome of mammals, including detailed information on ... a satellite paper for publication in the journal genome Biology. "The dogma right now is that there are ... switches that sit in specific places on the genome and induce genes. This is supposed to lead to a ...

Learning how the pieces responsible for interpreting the human genome work

... The human genome complete sequencing project in 2003 revealed the ... namely the proteins that bind to DNA. "If the genome provides the recipe to define a human being, the ... surprising data on the elements that form our genome and on its regulation, breaking some of the ...

Concordia University receives more than $22 million for genomics research

... $22 million to further advance the innovative genome research being conducted at Concordia. This investment results from the genome Canada Applied Genomics Research in Bioproducts ... and will include major contributions from both genome Canada and Gnome Qubec. Dr. Tsang was awarded ...

FANTOM findings boost for biologists

... BioMed Central's open access journals, including genome Biology and BMC Bioinformatics , provide ... how genes are controlled in mammals. In one genome Biology article, researchers have created a ... These data are detailed in a new article from genome Biology , and are also available as an integrated ...

The story of X -- evolution of a sex chromosome

... process of creating new sections of the genome that govern sexual differentiation in many ... Bachtrog also is completing assembly of the genome sequence for D. miranda, which is not among the 12 species of Drosophila currently targeted by the genome sequencing community. She hopes that the fly will ...

CSHL researchers explain process by which cells 'hide' potentially dangerous DNA segments

... six feet in length if stretched end to end. A genome of this size can squeeze into a cell's tiny ... The genes contained within these portions of the genome are effectively "silenced" because they cannot be ... machinery. These "hidden" parts of the genome also include highly repetitive, gene-poor, ...

University of Michigan installs second Genomatix Genome Analyzer

... the University of Michigan installed a Genomatix genome Analyzer (GGA) at its labs in Ann Arbor, MI. The ... user interface, which we found in the Genomatix genome Analyzer. The fact that it provides command line ... Genomatix, USA commented: "Placing our Genomatix genome Analyzer at the University of Michigan in an ...

Cancer Genomics Browser gives cancer researchers a powerful new tool

... who are now using powerful technologies for genome analysis and DNA sequencing in their efforts to ... disease that spreads throughout the body. A genome is an organism's complete set of DNA, and ... analyze the alterations that occur throughout the genome of a patient's cancer cells. Recent advances, ...

Getting down to cancer basics

... explains Dr Andy Futreal, co-leader of the Cancer genome Project at the Wellcome Trust Sanger Institute. ... we might expect from the International Cancer genome Consortium." The International Cancer genome Consortium (ICGC) seeks to catalogue genetic ...

Evolutionary origin of bacterial chromosomes revealed

... the Agrobacterium sequence information with the genome sequences of other bacteria suggests a general ... "Thanks to the efforts of the Agrobacterium genome Sequence Consortium and the wider research ... the inference of a general model for bacterial genome evolution. It appears that the transfer of genes ...

Gene exchange common among sex-manipulating bacteria

... University researchers have mapped the entire genome of a bacterium that infects a close relative of ... among the population. The studies of the whole genome have shown that these bacteria carry genes that ... the bacteria have stolen these genes from the genome in the host cell and that they now use them to ...

Hopkins scientists ID 10 genes associated with a risk factor for sudden cardiac death

... By focusing on 2.5 million sites in a genome of 3 billion sites, the scientists surveyed ... These common variants at 10 locations across the genome represent perhaps dozens of yet-to-be-identified ... compared to the collective vote. An individual's genome is important as part of the study's whole, but ...

New technique used to profile anthrax genome

... their gene expression. "Sequencing a bacterial genome has gotten to be pretty routine, but going to a ... way how each of the 5,000+ genes in B. anthracis genome is expressed and regulated." The RNA-Seq ... information for every gene in a bacterial genome allows researchers to take a more rational ...

200,000 rice mutants available worldwide for scientific investigation

... the approximately 57,000 genes that make up the genome of Oryza sativa. The International Rice ... scientists to link a physical location on the genome to a specific gene and its visible feature or ... the precise positions of mutations in the rice genome sequence, for each rice mutant plant. About 50 ...

Elephant shark genome sequence leads to discovery of color perception in deep-sea fish

... discovery, published in the March 2009 issue of genome Research , may enhance scientists' understanding ... proposed in 2005 as a valuable reference genome to understand the human genome. In a separate ... shark had retained more features of the ancestral genome than other vertebrates belonging to the same ...

Catching the common cold virus genome

... how and where evolution occurs in the rhinovirus genome and what this means for possible vaccines. The ... team was able to identify the parts of the virus genome that enable resistance to drugs and the human ... has responded to these defenses by changing its genome so that it is not so easily recognized. "The ...

Venter, Somerville and Church highlight DOE/JGI genomics of energy and environment meeting

... highlight the U.S. Department of Energy Joint genome Institute (DOE JGI) annual Genomics of Energy and ... improving biomass, its degradation, and biofuels; genome evolution and adaptation; new sequencing ... Peg Riley, University of Massachusetts, Microbial genome Evolution Lucy Shapiro, Stanford University, ...