Case Western Reserve University receives $1.66m grant from NIH for otoprotection research
... but preservation and a minimal density of spiral ganglion cells are required for an effective implant," said Zheng. Spiral ganglion cells are the cells that provide the sense of ... cochlea could promote the survival of the spiral ganglion neurons by release of neurotrophic substances or ...Gene therapy restores vision to mice with retinal degeneration
... the light-sensitive protein melanopsin in retinal ganglion cells. These specialized neurons receive light ... normally produced in 1 percent of retinal ganglion cells was found in about 10 percent of ganglion cells in the treated eyes but not in eyes that ...Mammals can be stimulated to regrow damaged inner retina nerve cells
... of specific growth factor stimulation on the proliferation of Mller glia cells. The researchers injected a substance into the retina to eliminate ganglion cells (a type of nerve cell found near the surface of the retina) and amacrine cells. Then by injecting the eye with epidermal growth factor (EGF), ...Retina adapts to seek the unexpected, ignore the commonplace
... his co-authors examined neural signals in retinal ganglion cells, which convey visual images from the eye to ... The spatio-temporal receptive fields of retinal ganglion cells change after a few seconds in a new ... recorded neural signals from the animals' retinal ganglion cells, testing whether adaptation to a different ...How Fruitflies Know It's Time for Lunch
... both in the mouth and in the pharynx and aim toward the subesophageal ganglion region of the fly's brain. How olfactory and gustatory signals influence ... extend to throat muscles—which is surprising because most subesophageal ganglion neurons have no connection to motor function. All together, these few hug ...Scientists use gene transfer technology and common virus to block neuropathic pain
... a carrier to deliver GAD to the nucleus of nerve cells in the dorsal root ganglion near the spine. In previous studies, the researchers have confirmed that ... to deliver other neurotrophic factors and pain-suppressing drugs to spinal ganglion cells. But Fink says the effect of the GAD-expressing vector is ...Scientists use gene transfer technology and common virus to block neuropathic pain in animals
... a carrier to deliver GAD to the nucleus of nerve cells in the dorsal root ganglion near the spine. In previous studies, the researchers have confirmed that ... to deliver other neurotrophic factors and pain-suppressing drugs to spinal ganglion cells. But Fink says the effect of the GAD-expressing vector is ...Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration
... were functional for the duration of the study. Scientists observed improvements including pupil response to light and response to light stimuli from ganglion cells, which form the circuitry to the brain. Swaroop explains that photoreceptors constitute "the first line of information capture in ...Researchers discover way to make cells in the eye sensitive to light
... uses light at different wavelengths to regenerate itself. In some forms of hereditary blindness photoreceptors are lost entirely, but the retinal ganglion cells, the cells which signal to the brain, remain intact. The researchers believe that by activating the melanopsin, these cells may gain the ...