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fragments in Biological News

UMMS researchers publish DNA identification of czar's children

... doing so, they determined the gender of the bone fragments and recovered profiles of nuclear DNA, including ... who used as little as possible of the bone fragments in order to preserve the remains for proper ... found in the first grave. "The newly found bone fragments were fragile and difficult to work with, but we ...

Genome of a heat and drought resistant cereal plant analyzed

... multiple times and then shredded into many small fragments by squeezing the DNA through a pressurized syringe. Finally the fragments are sequenced from both ends ans subsequentially the millions of small DNA fragments are assembled by elaborate computational methods ...

A simple fusion to jump-start evolution

... thermodynamic barrier, by incubating short RNA fragments in water of different temperatures and pH. ... fragments, generally within 14 hours. The RNA fragments came together as double-stranded structures then joined at the ends. The fragments did not have to be the same size, but the ...

Superglue from the sea

... it might be used for gluing together small bone fragments in fractured knees, wrists, elbows, ankles and ... until they heal. We see gluing the small fragments back into the joint." In their study, Stewart ... difficult to maintain alignment of small bone fragments by drilling them with screws and wires. An ...

UI and ISU establish shared DNA sequencing instrumentation

... whereby hundreds of thousands of DNA fragments are sequenced concurrently to generate hundreds ... capable of sequencing relatively long DNA fragments of 200 to 500 bases. This instrument will be ... instrument that can sequence relatively short DNA fragments of 18 to 36 bases. The instrument is capable of ...

American Chemical Society's Weekly PressPac -- July 16, 2008

... July 21, 2008 Screening of tiny chemical fragments may pay big dividends in drug discovery ... instead sort through a few thousand tiny chemical fragments that bind weakly to their targets. After screening, these weakly-binding fragments are then expanded into more potent substances by ...

Scientists confirm that parts of earliest genetic material may have come from the stars

... material which has been found in meteorite fragments is extraterrestrial in origin, in a paper ... The team discovered the molecules in rock fragments of the Murchison meteorite, which crashed in ... life may have adopted nucleobases from meteoritic fragments for use in genetic coding which enabled them to ...

New cheaper method for mapping disease genes

... building blocks of DNA: A, C, G and T). These fragments were then spread out and fixed onto a microscope slide so that several million fragments could be analysed simultaneously. These fragments were then rinsed in a fluid containing short DNA ...

Scientists determine drug target for the most potent botulinum neurotoxin

... the researchers designed four decoy protein fragments that mimic the structure of the protein to which ... The toxin then attaches itself to the decoy fragments instead of to the cells protein. This re-routing ... transform the most effective of the four protein fragments into a drug-like molecule before clinical testing ...

UC San Diego researchers eliminate drug discovery bottleneck

... to collect data on the weights of ring fragments as these fragments got progressively shorter and more numerous with ... of data on the weights of the various NRP ring fragments collected at each stage using mass spectrometry. ...

March GEOLOGY and GSA TODAY media highlights

... of continents than Alaska. Alaska is composed of fragments of crust that were transported northward on a ... belt (oceanic plates) descended beneath it. These fragments included volcanic islands and plateaus that ... in overlying mantle and crust. At least twice, fragments of the oceanic plates became doubled up, and, in ...

Liquid crystal phases of tiny DNA molecules point up new scenario for first life on Earth

... The new study shows that in a mixture of tiny fragments of DNA, those molecules capable of forming liquid ... tendencies, he said. We found that even tiny fragments of double helix DNA can spontaneously ... related precursor emerged as the molecular fragments most capable of condensing into liquid crystal ...

Nursery programs for corals receive TLC from NOAA this Independence Day

... This nursery presently holds approximately 500 fragments, and nursery fragments have already been used to restore four reefs where staghorn corals were ... The proposed plan includes expansion of fragment stocks (up to 4,000 fragments at this site) and the restoration of eight additional reefs over the next ...

Poison: It's what's for dinner

... designed to scan laboratory rat genes a glass slide containing tiny fragments of some 40,000 genes. The fragments bind to their counterparts in a sample of genetic material in this study, ...

Poison: It's what's for dinner

... designed to scan laboratory rat genes a glass slide containing tiny fragments of some 40,000 genes. The fragments bind to their counterparts in a sample of genetic material in this study, ...

Fossil fragments reveal 500-million-year-old monster predator

... are being published in this week's issue of Science . The fossil fragments puzzled together come from the famous 505 million year old Burgess Shale, ... would have been a formidable predator in its time. Although the first fragments were described nearly one hundred years ago, they were assumed to be part ...

Describing soils: Calibration tool for teaching soil rupture resistance

... together to get different rupture pressures. Manufactured or substitute fragments for natural soil fragments are described that can be used in the instruction of rupture resistance in ...

Researchers solve piece of large-scale gene silencing mystery

... (RNAi). Pikaard likens RNAi to a "search and destroy mission." fragments of RNA known as small interfering RNAs (siRNAs) prevent specific genes ... enzyme that chops up RNA transcripts into smaller segments. These smaller fragments of RNA become siRNAs, which then guide the de novo cytosine ...

Tool helps identify gene function in soybeans

... crop performance. The new genomic tool uses transposons, which are fragments of DNA that can "hop around" the genome. When these fragments move, they often land within an existing gene sequence, causing a ...

Microarray analysis improves prenatal diagnosis

... a particular point on the genome. The array starts with single-stranded fragments of DNA embedded on a glass slide to form the array, which is then exposed ... DNA reference and patient binds to DNA on the array. The color of the fragments will vary based on how much DNA from each binds to the DNA on the array. ...

Networks of small habitat patches can preserve urban biodiversity

... empirically test and verify an often used modelling approach where habitat fragments are seen as individual nodes in larger networks of interconnected habitat ... apart. Thus, many species are able to make use of the total of the habitat fragments in the network instead of relying on the individual habitat patches for ...

Sensitive laser instrument could aid search for life on Mars

... the width of a pencil point, the researchers can knock microscopic fragments off the mineral. Those fragments react with organic molecules to form detectable charged particles called ...

Discovery of natural compounds that could slow blood vessel growth

... University School of Medicine have discovered more than 100 human protein fragments that can slow or stop the growth of cells that make up new blood vessels. ... affected by excessive blood vessel growth." To identify short protein fragments peptides that can block blood vessel growth, the team started by looking ...

Cataloguing invisible life: Microbe genome emerges from lake sediment

... But his scientific legacy was disappointing a jumble of mystery DNA fragments belonging to thousands of unknown organisms. Now a team led by a ... so organisms. Researchers then were able to piece together carbon-13 DNA fragments to create one entire genome for Methylotenera mobilis, a microbe that eats ...

UT pathologists believe they have pinpointed Achilles heel of HIV

... utility and evolutionary implication of broadly neutralizing antibody fragments to HIV gp120 superantigenic epitope." First reported in the early ... genome has accumulated over millions of years of evolution a lot of viral fragments called endogenous retroviral sequences. These endogenous retroviral ...

8-day undersea mission begins experiment to improve coral reef restoration

... as increasing sea temperatures. The team has collected hundreds of coral fragments from two species: staghorn coral--which is listed as threatened under the ... would have died anyway. The researchers are splitting each of the fragments in half and placing one half in a shallow site (30 feet deep) and the ...

Pitt faculty receive awards to explore next-generation technologies

... DNA, chromosome-sized DNA molecules can be separated and studied, large fragments can be screened for mutations, and longer sequence fragments can be extracted. The technique might also be applied to RNA. The ...

American Chemical Society's Weekly PressPac -- March 19, 2008

... without the use of microorganisms. They identified dozens of key protein fragments involved in the complex infection process of the malaria parasite, from ... been tested to date. Likewise, identifying the disease-related protein fragments involved in the complex infection process of other transmittable diseases ...

Media highlights for February in Biophysical Journal

... delivery of drug molecules to their activation sites, and of healthy gene fragments to their target sites in gene therapy. The physics of translocation is ... example, to facilitate faster delivery of drug molecules or healthy gene fragments one needs to suppress the memory effects, while to advance single-molecule ...

New route for heredity bypasses DNA

... her colleagues have postulated that this programmed rearrangement of DNA fragments is guided by an existing "cache" of information in the form of a DNA or ... RNA template could provide a new set of rules for unscrambling the nuclear fragments in such a way as to reconstitute a working nucleus. "This wonderful ...

New south Florida nursery to focus on staghorn corals

... genetics on the resilience of this species to disturbance. A total of 250 fragments of staghorn coral have been collected to date, and placed on cement ... to assess growth and mortality patterns. It is expected that the staghorn fragments kept in the nursery will provide an expanding coral stock to be used in ...

New inhibitor has potential as cancer drug

... generation of blood vessels that is necessary for tumor growth. The fragments function as carriers of growth factors that can promote tumor growth in ... number of sulfate groups increased at the same time. The high-sulfated fragments released by the enzyme evince dramatically increased binding to certain ...

Major genetic breakthrough for ankylosing spondylitis brings treatment hope

... ARTS1 may hold the answer. A protein created by the HLA-B27 gene takes fragments of pathogens and displays them on the outside of immune cells. These fragments then trigger the immune system to fight against the pathogen. ARTS1 is ...

The reservoir of Marburg virus identified in a species of fruit bat

... situated South of the Tropic of Cancer. The search for viral genome fragments on 283 specimens of R. aegyptiacus showed the liver and spleen of four of ... antibodies. The simultaneous presence of specific antibodies and viral RNA fragments strongly suggested this bat species role as a non-symptom developing ...

Wasp genetics study suggests altruism evolved from maternal behavior

... specializes in bioinformatics and genomics. The new technique produced DNA fragments that were much shorter than those typically used. Because very little ... Kranthi Varala used a computer algorithm to compare the sequenced gene fragments to sequences from the honey bee genome, which has been fully sequenced. ...

Carnegie Mellon scientist uses mass spectrometer to weigh virus particle, von Willebrand factor

... used to determine the weight, structure and amount of small molecules or fragments of molecules. Conventional instruments, however, are not equipped to ... mass spectrometers, so most scientists break proteins down into smaller fragments before analyzing them in the mass spectrometer. Although an effective and ...

University of Toronto helps to 'barcode' the world's plants

... poisonous species and fragmentary material in forensic investigations. The technique will work on minute amounts of tissue and can be used on fragments of plant material, small seedlings, and in some cases digested or processed samples. The methodology will also be used immediately in global ...

The right messenger for a healthy immune response

... have now managed to show why this is the case: Beta-Interferon is a key regulator and of vital importance in enabling the immune system to display fragments of pathogens, so-called antigens. Immune cells present these antigens on their surface and in this way communicate with one another: antigens are the ...

Telomeres resemble DNA fragile sites

... fragile sites, suggesting that TRF1 protects telomeres from becoming fragile. Instead of a continuous string of DNA, the telomeres were broken into fragments of twos and threes. To see if the replication fork stalls at telomeres, de Lange and Sfeir joined forces with Carl L. Schildkraut, a researcher at ...

The tiny difference in the genes of bacteria

... certain dyes. Each dyed DNA fragment recognizes a single tandem repeat, binding at it. As a result, the researchers receive, for example, six red fragments binding a tandem of six repetitions. Then, the researchers analyzed the tandem repeats marked with dyed fragments: Every bacteria strain differs in ...
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