Expressed in Biological News

A biological basis for the 8-hour workday?

... analysis showed that more than 3,000 genes were expressed on a circadian rhythm which account for approximately 4% of all of the genes expressed in the liver. Additionally, 260 genes were expressed on a 12-hour cycle and 63 genes ...

Study finds blood cells can be reprogrammed to act as embryonic stem cells

... carrying reprogramming factors, genes normally expressed in embryonic stem cells that can reset the blood ... other types of cells. Indeed, the iPS cell lines expressed the same markers as ES cells and further shared ... any type can develop. These differentiated cells expressed genes for all three embryonic germ layers (the ...

Plant gene mapping may lead to better biofuel production

... UPTON, NY -- By creating a "family tree" of genes expressed in one form of woody plant and a less woody, ... They then looked at how the genes were expressed activated to make their enzyme products in ... interest to Liu's group were a number of genes expressed at high levels in the woody plant tissues. ...

UCR scientists identify stem-cell genes that help form plant organs

... at UC Riverside has identified all the genes expressed in the plant's stem cells. The researchers also identified all the genes expressed in two other SAM cells: niche cells (which are ... have done so far is to find out which genes are expressed and where. One of the future challenges is to ...

Tailor-made recombinant proteins in mammals

... coli , but most protein pharmaceuticals must be expressed in cultured mammalian cells. The researchers have ... they previous developed for recombinant proteins expressed in bacteria, to label proteins that can only be expressed by mammalian systems. "Proteins made with ...

Snails and humans use same genes to tell right from left

... that - in all vertebrates checked to date - is expressed on the left side of the body and necessary to set ... on only one side of the body, but nodal is always expressed on the left side in all vertebrates, which is ... tests showed that nodal and Pitx were active or expressed on the right side of embryos in the right-handed ...

Modified gene targets cancer cells a thousand times more often than healthy cells

... Hine, were investigating Rad51, a protein that is expressed at about five times higher level in cancer cells ... Further tests showed that the altered Rad51 was expressed in some cancer cells as much as 12,500 times as ... in DNA repair, which explains why it's more often expressed in cancer cells. Cancer cells reproduce at ...

The medium is the message: Manipulating salmonella in spaceflight curtails infectiousness

... Interestingly, many of the 167 differentially expressed genes observed in the space-traveling microbes ... to regulate one third of the 167 differentially expressed genes in the spaceflight LB cultures. ... genes were also found to be differentially expressed in the M9 flight samples. In addition to Hfq's ...

Statins may prevent miscarriages

... activates another protein, tissue factor, that is expressed on the surface of certain white blood cells ... mice that had APS and discovered that these cells expressed certain receptors called PAR2 (protease-activated ... tissue factor (diminish the number of molecules expressed on the surface of the cell). Dr. Girardi and ...

Nurture over nature

... that up to one-third of genes are differentially expressed due to where and how the Moroccan Amazighs live. ... About 30 percent of genes were differentially expressed between urban dwellers and mountain agrarians. ... profiles," Idaghdour says. "The same gene can be expressed in the city but not in a rural place because of ...

Doctors may be giving the wrong dosage of adrenaline in an emergency because of labelling

... of adrenaline contained in the ampoule is usually expressed as both a dose (1 mg of the drug per 1 mL of salt ... with labels that had the amount of adrenaline expressed as a ratio. The researchers then measured the ... doctors out of 14 whose ampoules with labels that expressed the amount of adrenaline as a ratio overdosed ...

A search for biomarkers for early detection of colorectal cancer

... Protein 5 (TXNDC5) were differentially expressed in colorectal adenoma. The research article ... of molecular pathology, found 27 differentially expressed proteins in colorectal adenoma using two ... analysis clearly validated 2 differentially expressed proteins, mimecan downregulation and TXNDC5 ...

Targeting nerve growth factor may cure liver cancer

... showed that NGF and its receptor trkANGF were expressed in the liver of the patients troubled with liver ... a cell, there should be its specific receptor expressed on the surface of the target cell. Since both NGF and its specific receptor are abnormally expressed in the liver of patients, NGF seems to ...

JCI table of contents: Aug. 16, 2007

... Furthermore, individuals with neuroblastomas that expressed high levels of MYCN and whose cancer had spread ... marrow than individuals with neuroblastomas that expressed low levels of MYCN and whose cancer had spread to ... the KL protein resulting from this mutation was expressed and secreted at lower levels than normal KL and ...

Army study improves ability to predict drinking water needs

... costs, according to Dr. Cheuvront. The Institute of Medicine has also expressed interest in improving the prediction of water needs for the general public ... own genes. The Shapiro equation, developed more than 25 years ago, is expressed as (msw (gm-2h-1) = 27.9 Ereq (Emax)-0.455, where: Ereq is ...

Major breakthrough in early detection and prevention of AMD

... that CCR3 a molecule also implicated in inflammatory processes is expressed on the surface of CNV vessels in humans but is absent from normal vascular ... the CNV process involved in AMD. If researchers can determine why CCR3 is expressed in the CNV of AMD patients, they could further understand AMD disease ...

Gene evolution process discovered

... have believed for many years that differences in the way genes are expressed into functional proteins is what differentiates one species from another ... the repertoire of genes that REST regulates, in particular those which are expressed in the central nervous system. The team compared 16 whole genome sequences ...

Huntington's disease deciphered

... huntingtin gene activates a particular enzyme, called JNK3, which is expressed only in neurons and, further, to show what effect activation of that ... bad at 4." The second problem, according to Brady, is that the gene is expressed not just in the nervous system but in other parts of the body. However, ...

MicroRNAs grease the cell's circadian clockwork

... that reaches a peak once a day. A large number of circadian genes are expressed by organs such as the liver, whose activity needs to be precisely ... involved in metabolism, including that of cholesterol and lipids, are expressed in liver cells in a cyclic fashion. Many of them are also influenced by ...

Random picks better than complicated process in gene identification

... of genes that perform simple housekeeping functions, whereas others expressed in smaller numbers are charged with more complex and important functions. ... DNA sequencers. "Normalization used to be required because commonly expressed genes would swamp the signal of rare genes," DeWoody said. "But ...

Hebrew University researchers neutralize tumor growth in embryonic stem cell therapy

... is involved in this unique tumorigenicity. This gene, called survivin, is expressed in most cancers and in early stage embryos, but it is almost completely absent from mature normal tissues. The survivin gene is especially highly expressed in undifferentiated human embryonic stem cells and in their derived ....

Genes from tiny marine algae suggest unsuspected avenues for new research

... for those genes [for sexual reproduction], we could look for them being expressed in the field. Then we could try to figure out the conditions triggering ... have no known function. She explains, "We know they're real-they're expressed and we've seen them in other organisms-but they're not genes that anyone ...

Scientists develop method for comprehensive proteome analysis

... Wolf. "Proteome analysis gives us a snapshot of what proteins are being expressed in the cell at any given point in time. This can tell us how protein ... which is not quite the entire proteome. The remaining 400 are only expressed during S. pombe 's mating state. S. pombe is often used as a model ...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

... lung cancers. The experimental vaccine targets MAGE-A3, a protein expressed in certain cancer cells but not in normal cells. Thirty-five percent of ... at Rush. "In a trial of early-stage lung cancer patients whose tumors expressed MAGE-A3, preliminary results showed that the vaccination reduced the risk ...

UC Davis researchers identify a protein that may help breast cancer spread, beat cancer drugs

... Kermit Carraway, senior author of the study, knew that Muc4 was not always expressed in primary breast cancer tumors, yet it could be present in lymph node ... other cancers that show aggressive properties. For example, Muc4 is also expressed in pancreatic, lung and ovarian tumor cells. "Muc4 is likely a central ...

Mayo Clinic researchers discover and manipulate molecular interplay that moves cancer cells

... tumor cells of PKD1 and found that their motility increased. They then expressed activated PKD1 in tumor cells and found that movement was blocked. PKD1 is ... a negative regulator of directed cell migration, and if PKD1 is not expressed in tumor cells, slingshot will become active and will contribute to the ...

Tips from the American Journal of Pathology

... patients. They found that markers of the unfolded protein response were expressed in areas of tau accumulation in patients with Alzheimer's disease. These unfolded protein response-related proteins were expressed early, in pre-tangle neurons, but were absent in tangle neurons. This ...

Molecular fingerprints point the way to earlier cancer diagnosis and more targeted treatment

... cancer growing inside. Scientists also need to continue to look at genes expressed by tumors and the proteins expressed by those genes to get the bigger picture. "It's basically a systems ...

Scientists discover why teeth form in a single row

... results in extra teeth outside of the normal row, but also that Osr2 is expressed in increasing concentration in the jaw mesenchyme as you move from the ... first molars, but no additional teeth. Thus, without Osr2, enough BMP4 was expressed for the first molar teeth to grow, but without Msx1, the BMP4 signal was ...

Discovery could lead to a new animal model for hepatitis C

... cells express genes that allow uptake of the virus, genes that are not expressed in other human and nonhuman cells, explains Rice. In past years, three ... Sinai School of Medicine in New York, first cloned all the genes that were expressed in liver cells and then delivered them to mouse cells. "Then, going ...

Gene switch sites found mainly on 'shores,' not just 'islands' of the human genome

... of several so-called epigenetic modifications that affect which genes are expressed without changing the DNA sequence itself. Previous studies have suggested ... gene, a place with the potential to affect whether that gene is expressed or not and to what extent. However, Feinberg and co-investigator Rafael ...

When it comes to sleep research, fruit flies and people make unlikely bedfellows

... of the fruit fly's sleep-regulating enzyme (DBT protein kinase) were expressed in insect cells and purified to determine how well each would work. The ... The mutant proteins (either the fruit fly or vertebrate protein) were expressed in the fruit fly's circadian neurons and produced very similar effects on ...

Attitudes towards assisted reproduction and preimplantation genetic diagnosis

... and stands below it in the rest. The most favorable opinions are expressed in the Czech Republic, Spain, and Israel, and the most unfavorable in ... below the midpoint on the scale in all countries. The firmest rejection is expressed in Poland (1.1), Italy (2.4), Austria (2.9) and Japan (3.0). ...

Wistar scientists find key to keeping killer T cells in prime shape for fighting infection, cancer

... see a picture emerging of a really tuneable array of inhibitory receptors expressed on T cells," Wherry says. "That suggests it may be possible to not only ... found that a receptor known as programmed death-1 (PD-1) was highly expressed by exhausted T cells from chronically infected mice but not from mice that ...

Fried purple tomatoes

... Scientists have expressed genes from snapdragon in tomatoes to grow purple tomatoes high in ... the best protection against disease. In this study the scientists expressed two genes from snapdragon that induce the production of anthocyanins in ...

bioMETRX, Inc. Welcomes Residential and Commercial Security Expert to Board of Directors

... that could cause actual results to differ materially from those expressed in the forward-looking statements, including, but not limited to, certain ... that could cause actual results to differ materially from those expressed in the forward-looking statements, including, but not limited to, certain ...

bioMETRX, Inc. Signs Deal To Acquire Controlling Interest in Biometric Solutions, LLC

... that could cause actual results to differ materially from those expressed in the forward-looking statements, including, but not limited to, certain ... that could cause actual results to differ materially from those expressed in the forward-looking statements, including, but not limited to, certain ...

Scientists identify gene that may contribute to improved rice yield

... by many cell types. In fact, the corresponding gene in wild rice is not expressed specifically." The team also found that the GIF1 gene is one of the ... in the GIF1 gene," said Ma. "This process has caused GIF1 to be expressed specifically in the vascular tissue and, thus, to produce larger rice ...

Site used by sodium to control sensitivity of certain potassium ion channels

... By examining in which cells these sodium-sensitive channels are expressed and how sodium may be critical for the function of these cells, we hope to ... express the Kir5.1 channel, he added. In kidney cells, the Kir channel is expressed in cells that are responsible for reabsorbing sodium, a process relevant ...

Giant grass offers clues to growing corn in cooler climes, researchers report

... Long said. To test how cold temperatures affect the protein when it is expressed in cells at high concentrations, post-doctoral fellow Dafu Wang cloned the ... step for the researchers is to develop a corn plant in which this gene is expressed at high levels to determine if that will make the corn more tolerant of ...