exons

Genrate: a generative model that finds and scores new genes and exons in genomic microarray data

...rogress in using microarrays to validate predicted exons in genome sequence and find new gene structures. H...larity of expression profiles, and arrangements of exons in the genome. We have taken a Bayesian approach and developed GenRate, a generative model that acc...

Carnegie Mellon University research reveals how cells process large genes

...s). During processing, introns are snipped out and exons pasted together to form a template for proteins ca...splicing is used to control the removal of certain exons from mRNAs, generating structural and functional variation among the gene products." ...

Reversal of role for a viral protein associated with the development of lymphoma

...s). During processing, introns are snipped out and exons pasted together to form a template for proteins ca...splicing is used to control the removal of certain exons from mRNAs, generating structural and functional variation among the gene products." ...

Modification of program enables prediction of gene transcription

... 6,000. "In the human genome, we found many extra exons on genes that were already known, or in some cases...this integrated model that looks for both kinds of exons in both parts of the gene, we're able to convert a blind guessing game to a multiple choice question...

Study provides insight into cellular defenses against genetic mutation

...A is made of both "must-read" pieces of RNA called exons that code for the building of proteins, and pieces...cellular machines that re-assemble end to end only exons in the final template for protein construction. In recent years, Maquat's team has confirmed that co...

RNA splicing occurs in nerve-cell dendrites

..., a gene is copied into mRNA, which possesses both exons (mature mRNA regions destined to code for proteins... made into protein. Should the RNA have different exons spliced in and out of it, then different proteins can be made from this RNA. The Eberwine lab was su...

Living view in animals shows how cells decide to make proteins

...rm a new RNA molecule. In the process, some of the exons are retained while others are excluded. The exons that are retained in the final RNA determine which proteins the RNA produces within the cell. Th...

Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription

...gions in genes) are significantly less stable than exons (coding sequences in genes), suggesting that stabl...stability of DNA/DNA and mRNA/DNA duplexes of both exons and introns. In contrast, an inverse relationship exists between mRNA levels and stability of the re...

Human genetic 'deserts' are teeming with significant life

...a tissue-specific manner previously unknown set of exons [the regions of DNA within a gene that are transcribed to messenger RNA] outside the current boundaries of the annotated genes ”, Professor Reymond will say. He and his team are among the many international collaborators working together on a...