Essential in Biological News

Munich researchers discover new target for tailored antibiotics

... by interfering with their ability to produce essential compounds. Ever more bacterial strains are ... The cells of virtually all life forms synthesize essential natural substances belonging to the class of ... a large number of other organisms generate these essential metabolites via the so-called mevalonate pathway. ...

Mystery E. coli genes essential for survival of many species

... previously unknown genes that, it turns out, are essential for the survival of E. coli and one out of the ... didn't expect to find any more genes that are essential for survival! "Finding out that these genes are essential in E. coli and also appear in the genomes of ...

Rampant helper syndrome

... special pockets in the proteins and carry out essential metabolic functions. The living organism itself ... vitamin deficiencies are a harsh reminder of how essential these molecules are. Methanogenic bacteria ... special proteins of methanogenic bacteria, and is essential for methane biosynthesis. Cofactor F0/F420 is a ...

Trans fats hinder multiple steps in blood flow regulation pathways

... changing the arrangement of double bonds in the essential fatty acids in the oil and "saturating" the ... Trans fats displace and cannot replace the essential fatty acids linoleic acid (omega-6) and linolenic ... to interfere with an enzyme that converts the essential fatty acid linoleic acid into arachidonic acid, ...

Powe Award supports research on how enzymes enable the pathogenicity of 2 human disease organisms

... Award for his research on enzymes that are essential for infection in two important human pathogens. ... and Aspergillus fumigatus . Iron is essential for all life. M. tubercuolis and A. fumigatus ... (FAD). The function of these enzymes is essential to form the hydroxamate potion of the ...

Nutricia launches Nutra Neocate, weaning product designed for cows’ milk protein allergy

... and is designed to provide children with the key essential nutrients they need for development. With its ... trace of cows' milk. Neocate Nutra contains key essential nutrients potentially missing from a dairy-free ... risks.1,3 Good nutrition is not only essential for a child's physical and emotional well-being, ...

New hope for advances in treating malaria

... the enzyme dihydroorotate dehydrogenase (DHODH) - essential to the growth of the parasite - from working, ... to drugs." He adds: "DHODH in humans is not an essential enzyme, so by concentrating our studies on it we ... by the rate of resistance. Therefore it is essential that new products work effectively in combination ...

Microbes in mud flats clean up oil spill chemicals

... occurring naturally in coastal mudflats have an essential role to play in cleaning up pollution by breaking ... at Harrogate today (Monday 30 April), reveals essential differences in the speed of degradation of the ... refineries and petrochemical facilities it is essential that mudflats are preserved to provide a natural ...

Scripps research team identifies key molecules that inhibit viral production

... protein among all HCV genotypes, plays several essential roles in the viral cycle in the host cell; ... the assembly of the hepatitis C nucleocapsid, an essential step in the formation of infectious viral ... coat the capsid. This core protein plays an essential role in the HCV cycle during assembly and release ...

Cancer-causing gene discovery suggests new therapies

... RNA the first step in making proteins that are essential for cell growth and function. But the new ... on protein production. This demonstrates how essential this process is for cancer formation." To ... changes in protein levels of a key gene that is essential for normal distribution of genetic material ...

Biomedical researchers create artificial human bone marrow in a test tube

... bone marrow," Kotov said. "It has two of the essential functions of bone marrow. It can replicate blood ... of the polymer molded by spheres is very essential for reproducibility of the drug tests and ... products. "Certain stem cells that are essential for immunity and blood production are able to ...

Oil spray reduces greenhouse gas emissions from pig finishing barns

... oil spray techniquesvegetable oil sprinkling, essential oil misting, and misting of essential oil with waterto reduce these emissions. Results ... barns. Treatments of oil sprinkling, misting of essential oils, and misting ...

Pregnant women with asthma can be more confident about some medicines

... and can be regarded as safe. More trials of other essential medicines are necessary however. According to the ... Institute's Director, Professor Peter Sawicki. essential medicines are generally not researched enough in ... need more reliable knowledge about the effects of essential medicines in pregnancy." Avoiding asthma ...

Scripps research scientists identify blood component that turns bacteria virulent

... Ph.D., and colleagues. "We have identified an essential component for the induction of virulence gene ... by the gene number BAS2714-12that was shown to be essential to transporting bicarbonate. As a group, ... production, suggesting that CO2 activity is not essential to virulence factor induction and that ...

A model to measure soil health in the era of bioenergy

... practices. The presence of these materials is essential as they do everything from providing plants with ... the ability to predict the loss of SOC and SOM is essential to maintaining productive crops. The model can be ... and sufficient biomass to prevent erosion is essential for decisions on land use for food, fiber, feed, ...

Female embryonic sexual development driven by universal factor

... A gene essential to the growth and development of most organ ... region of the Y chromosome) that appeared to be essential for testes formation. But when researchers ... The "Z" hypothesis explained why SRY appeared essential for testes development. When it is present, SRY ...

In the war against diseases, nerve cells need their armor

... and the Universit de Montral have discovered an essential mechanism for the maintenance of the normal ... known for just over 10 years that netrin is essential for normal development of the nervous system, and ... In order to protect and restore myelin it is essential to to understand the molecules involved in these ...

Bacteria manage perfume oil production from grass

... These bacteria seem to promote the production of essential oils, but also they change the molecular ... locations that are closely associated with the essential oil. The Vetiver grass is the only grass cultivated specifically for its root essential oil, which is made up of chemicals called ...

New lab manual focuses on essential methods for purifying and characterizing proteins

... day-to-day use in the laboratory, it includes essential step-wise protocols as well as background ... Understanding how proteins function is an essential part of many biological research endeavors. The ... out the manual is an extensive appendix of essential methods for quantifying protein concentration, ...

The structure of the Mre11 protein bound to DNA

... central component of the MRN complex performs its essential functions. The core of the MRN complex is the ... for the work of other repair proteins, an essential function of Mre11 on which successful homologous ... disease. Prompt and accurate DNA repair is so essential to life that many of the molecular machines that ...

Elsevier congratulates its British Medical Association Award winning medical authors and editors

... presented the awards. Elsevier's Netter's essential Histology by William Ovalle and Patrick Nahirney ... Surgery: H George Burkitt and others - essential Surgery: Problems, Diagnosis and Management, 4th ... Book Award: Ovalle and Nahirney - Netter's essential Histology BMA Student Textbook Award: ...

1/3 of reef-building corals face extinction

... in their soft tissues and provide the coral with essential nutrients and energy from photosynthesis and are ... funding of local conservation practices also are essential to protect the foundation of beautiful and ... 20,000 marine plants and animals, providing an essential baseline for conservation plans around the world, ...

UGA researchers discover mechanism that explains how cancer enzyme winds up on ends of chromosomes

... have shown a mechanism that explains how two essential components of human telomerasenormally active ... University of Georgia Cancer Center. The two essential components of human telomerase are telomerase RNA ... in human telomerase trafficking and is essential for the localization of telomerase RNA both to ...

Great Ape Trust's Wich lead author of Oryx paper on continuing orangutan population declines

... of Conservation . Conservation action essential to survival of orangutans, found only on the ... be attained, according to the experts. "It is essential that conservation measures are taken to protect ... in political will," Wich et al wrote. "It is essential that funding for environmental services reaches ...

A single mechanism for hypertension, insulin resistance and immune suppression

... Many of the 75 million Americans with essential hypertension also develop diabetes and other ... problems, there is a tendency to forget that essential hypertension affects about the same percentage of ... rat (SHR). The SHR strain is a model for essential hypertension in humans because both the rodent ...

Thinking ahead: Bacteria anticipate coming changes in their environment

... to a higher temperature, many of the genes essential for aerobic respiration were practically turned ... following a temperature increase is not essential to E. coli's survival," says Tavazoie. "On the ... logic-solving networks." Pared down to their essential elements, however, the networks revealed a simple ...

Mouse can do without man's most treasured genes

... student Liao focused their study on so-called essential genes---genes which, through their effects on ... maturity and reproduce. They then homed in on 120 essential human genes for which the mouse has an identical ... are deleted, or "knocked out." If those 120 essential human genes are ...

Silicon's effect on sunflowers studied

... that are found in normal plant tissue that are essential for the completion of the life cycle of the ... in mineral soil, is not considered to be an essential nutrient for most plants, there has been limited ... for years since it is not considered an essential element for plant growth and development. ...

Elevated carbon dioxide changes soil microbe mix below plants

... These changes could increase the availability of essential soil nutrients, thereby supporting increased ... especially via effects on the cycling of essential elements, will be important for evaluating the ... plant roots and help to provide the plants with essential minerals a decrease in fungi that commonly ...

Tumor genome analysis unveils new insights into lung cancer

... and Harvard Medical School in Boston. It lays an essential foundation, and has already pinpointed an ... remain to be discovered. The gene NKX2-1 is essential in the development of cells that line the alveoli ... RNA interference, they determined that NKX2-1 is essential for the survival of lung cancer cell lines that ...

Humans 'damaging the oceans'

... threats for the oceans and their life," Andrew and Mike say. "Given how essential the oceans are to how our entire planet functions it is vital that we ... cautions. "On a global scale, an immediate reduction in CO2 emissions is essential to minimize future human-induced climate change." The oceans can also ...

Grant supports LSUHSC research on how like cell receptor systems determine very different functions

... of a pathway might be targeted therapeutically while not eliminating all essential housekeeping functions of the pathway," Dr. Catling says. "The beauty of ... outcomes." These key personnel and the data they generate are essential to submit a competitive renewal of this RO1 grant in November. ...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

... seen as the main cause of mental and certain neurological disorders. The essential knowledge of central features of neurotransmission was first gained at the ... of neurons in the brain is central to understanding the mind, and essential for the understanding and treatment of mental disorders. On a practical ...

Scientists capture the first image of memories being made

... in French . The ability to learn and to establish new memories is essential to our daily existence and identity; enabling us to navigate through the ... considering what might be going on in the brain at a molecular level two essential properties of memory need to be taken into account. First, because a lot ...

Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii

... ammonia via bacterial enzymes called nitrogenases. Nitrogen fixation is essential for life since different nitrogen-containing molecules are used to produce ... family. The completion of the A. vinelandii genome will serve as an essential phylogenetic anchor point for comparative genomics work with other ....

American Society for Microbiology honors Deborah T. Hung

... by using chemical genetics and small molecular screening to dissect essential steps in pathogenesis. She published her findingsa new small ... chemicals that can manipulate it and by identifying genes that are essential for it. Dr. Hung received both her Ph.D. in Chemistry and her M.D. ...

Heart protein regulates blood vessel maintenance

... thought to cause high blood pressure. Our study demonstrates that FHL2 is essential in modulating the physical state of vSMCs, which is essential in regulating vascular motor function," says Hata. ...

Genome projects launched for three extreme-environment animals

... of 20,000󈞅,000. The data from this sequencing project will provide essential tools for understanding its unique environmental adaptations and for ... project that was previously launched at BGI-Shenzhen, it also provide an essential scientific basis for further studies on extreme-climate adaptation, ...

Uncooperative voltage sensors

... on new experimental evidence that advances previous conclusions about the essential features of the Shaker K+ channel, a voltage-gated potassium (Kv) channel. ... Medical College) explains in his JGP commentary: "Many of the essential features of the voltage-sensing mechanism are known [including consensus ...

Springer partners with the American Society for Biochemistry and Molecular Biology

... unifying concepts and theory from biology, chemistry and physics that are essential for understanding the molecular life sciences and will also include ... between cutting-edge science and the foundational theories and principles essential for understanding the molecular nature of life processes. It will provide ...