Protein that triggers plant cell division revealed by researchers
... a doctoral candidate, both in the Biology Department, tracked BASL in epidermal cells of Arabidopsis, a small plant used for genetic studies. The epidermis of Arabidopsis contains small pores called stomata that allow the plant to breathe and these stomata are generated by asymmetric cell divisions. The ...Scientists film inner workings of the immune system
... viewed in real time. "Using multi-photon microscopy, we studied dendritic cells in the skin. Under normal conditions we found the cells in the epidermis (top layer) were static, whereas in the dermis (second layer) they were very active, moving around as though seeking out pathogens," explains ...Salk researchers successfully reprogram keratinocytes attached to a single hair
... constituent of hair, nails and skin. They originate in the basal layer of the epidermis, from where they move up through the different layers of the epidermis and are eventually shed. While scientists have successfully reprogrammed different types of mouse cells (fibroblasts, liver and intestinal cells), ...UW science photo takes second in national contest
... buckling is well-studied and emerges in many places in nature, Eun says. Our fingertips get crinkly in the bathtub, for example, because the flexible epidermis swells with water, while the underlying tissue it's attached to does not, causing the skin to wrinkle. According to the competition's Web site, ...Scientists discover important beauty secret for balanced skin color and tone
... to manipulate than melanocytes. Medical conditions that sometimes require the use of bioengineered skin grafts include severe burns, scleroderma, epidermis bullosa, diabetes, and venous leg ulcers. In addition, the studys senior researcher, Raymond Boissy, says this study also could help the quality of ...Scientists develope a new model of artificial canine skin
... To develop this model, cells from the epidermis (keratocytes) and the dermis (fibroblasts) from ... skin and joints), were used as a support for the epidermis cells, which were grown on its surface and were ... Additionally, the expression of the dermis and epidermis proteins follows the same pattern of expression ...Researchers learn what sparks plant growth
... cell-cell communication during growth, from the epidermis to the inner layers. Such a mode of communication ... said. "Our paper shows very clearly that the epidermis is in control—in both driving and restricting ... addition, our studies show that the cells in the epidermis "talk" to the cells in the inner layers, ...From managing sugar to managing healing
... in rats treated topically with insulin healed faster"surface cells in the epidermis covered the wound more quickly and cells in the dermis, the deeper part of ... impact of topical insulin on keratinocytes, the cells that regenerate the epidermis after wounding, and on microvascular endothelial cells, the cells that ...Researchers identify a key regulator for skin stem cells
... a role in maintaining adult follicle cells, it would also be present in embryonic skin, which consists mainly of stem cells. When they analyzed the epidermis of embryonic mice, they found that theTcf3 gene was, indeed, active in the embryonic skin stem cells. The researchers next sought to pinpoint ...Researchers offer clues to how leaves patterns are formed
... team identified cells within individual veins that transport the hormone auxin in two opposite directions. He also showed for the first time that the epidermis of the leaf is very important in the transport of this hormone and in the formation of the veins. One of the objections to the idea that veins ...EGF receptor activation prevents microbes from going more than skin deep
... of the skin against the potential skin pathogen Staphylococcus aureus was increased by activation of EGFR, and that the concentrations of AMPs in the epidermis of wounded skin exceeded those necessary to suppress or prevent the growth of foreign microbes. The results of this study demonstrate that wounding ...Gene first linked to rare disease may trigger skin cancer, other tumors
... the researchers said. Indeed, the group noticed an intriguing trend--most of the tumors found in the mutant mice developed from cells of the epidermis rather than the hair-follicle cells thought to be involved in cylindromatosis. They therefore conducted a preliminary analysis of CYLD levels in ...Plants have a double line of defence
... to powdery mildews. If these genes are defective, or if the protein they code is missing in the plant cells, the fungus can invade the leaf epidermis cells more frequently. For that reason the scientists looked particularly at the question of exactly which function the PEN2 protein has in the ...Researchers discover how tumor suppressor gene works
... of a gene known as "p16." Normally, p16 keeps cells from growing rapidly, a condition that sometimes leads to tumor formation. Working with mouse epidermis and cultured human melanoma and nonmelanoma cancer cells, the team found that p16 inactivates key enzymes -- called JNK 1 and JNK 2 -- in the ....Study: Well-known protein helps stem cells become secretory cells
... factor involved in keeping secretory genes expressed at high levels, and Fork head acts through it," said Andrew. CrebA's role in the fruit fly's epidermis gives it secretion-promoting powers there as well, the researchers note. In fruit flies, epidermal cells secrete the cuticle, a protective covering ...Hirsute Or Hairless? Two Proteins May Spell The Difference
... of E-cadherin. Artificially sustaining Snail expression in the skin of transgenic mice caused abnormal levels of cell proliferation in the epidermis and reduced cell adhesion. Working with skin keratinocytes, precursors of hair fibers, Fuchs and colleagues explored several signaling proteins ...