Edema in Biological News

OSU technologies funded for development

... of a 3D Human Tissue Model for Screening Potential Diabetic Macular edema Therapeutics, School of Chemical Engineering. With a current 3D human ... model, which will be used to screen potential diabetic macular edema therapeutics. Charlesson LLC, an Oklahoma-based company already engaged ...

Scientists present 'moving' theory behind bacterial decision-making

... regulators studied by the NC State biochemists, called AbrB, helps control the production of the three toxins in anthrax: lethal factor, edema factor and protective antigen. Production of all three of these toxins is necessary to make anthrax lethal. Cavanagh and Bobay say that knowledge ...

Opening a channel for salt retention

... ENaC. The sustained yet reversible action of S3969 makes it a good model to build future drugs aimed at improving hypotension, neonatal pulmonary edema (reduced sodium uptake in the lungs can lead to fluid retention), and renal salt wasting disorders. ...

Early exposure to common weed killer impairs amphibian development

... Twelve to 24 hours after exposure to atrazine, tadpoles were examined for abnormal heart growth, visceral hemorrhaging, intestinal coiling, edema and apoptosis (normal cell death that is "programmed" by the body). Compared with control populations, the tadpoles that were exposed to atrazine ...

The endocannabinoids: Functional roles and therapeutic opportunities

... that the endocannabinoid system, through various biological routes, lowers the damage caused by brain trauma. Thus, it helps to attenuate the brain edema and the neurological injuries caused by it (Panikashvili et al., 2001; Panikashvili et al., 2006). Clinical importance Furthermore it is ...

Study shows pine bark naturally decreases severe chronic venous insufficiency

... Pycnogenol® to be more effective in reducing edema (leg swelling), tight calves, skin alterations, ... Like varicose veins, spider veins also develop if edema is left untreated. "Chronic venous ... was recorded by patients. A second evaluation of edema was made by another physician. After eight ...

Critical step traced in anthrax infection

... membrane. The pore permits the other two proteins, lethal factor (LF) and edema factor (EF), to enter the cell interior, where the factors interfere with ... lumen of the membrane pore is smaller than the folded lethal factor and edema factor, these proteins must first unfold before being actively ...

Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax

... lung. When the spores germinate, they are transformed into vegetative cells that produce three components contributing to virulence--lethal toxin, edema toxin, and capsule. The capsule surrounds the vegetative cell and prevents it from being ingested by host white blood cells that would otherwise ...

Viagra improves high altitude exercise performance up to 45% for some

... don't know why some people have trouble at altitude and may develop illnesses such as acute mountain sickness or high altitude pulmonary edema while others adapt quickly. Studies like this may help identify some of the underlying differences between people and lead to better treatments. ...

Healing honey: The sweet evidence revealed

... existing infection, it protects wounds from additional infection Honey debrides wounds and removes malodor Honey's anti-inflammatory activity reduces edema and minimizes scarring Honey stimulates growth of granulation and epithelial tissues to speed healing The review article was written by Dr. P.C. ...

Driver of anthrax toxicity could lead to late-stage therapy

... concern. The virulence of the bacteria depends on separate complexes formed by interaction of a carrier protein, protective antigen, with lethal and edema factors responsible for the toxic effects and swelling that impairs the host's immune response. In the current study, the researchers inactivated ...

UCSD study finds anthrax toxins also harmful to fruit flies

... Guichard, a biologist at UCSD and lead author of the study, tracked the ways that two active anthrax toxins, known as lethal factor, or LF, and edema factor, EF, cause cellular damage and death in the fruit fly Drosophila melanogaster. These toxins are required for the anthrax bacterium Bacillus ...