dynein

Molecular Motors Cooperate In Moving Cellular Cargo, Study Shows

...ned. "We discovered that two molecular motors -- dynein and kinesin -- do not compete for control, even th...e a living cell. "Our measurements show that both dynein and kinesin carry the peroxisomes in a step-by-step fashion, moving about 8 nanometers per step," sa...

Marathon of nano-sprinters

...an be considered the fuel of the cell. Kinesin and dynein motors move along microtubules and myosins move along actin filaments. The step sizes of these motors are of the order of 10 nm. By stepping in a directed fash-ion along filaments, the motors pull cargo particles which are much larger than the mo-tor...

A new way of looking at molecular motors

...le, yeast uses six kinesins, five myosins, and one dynein while mammals have genes for more than 40 kinesins, 40 myosins and more than a dozen dyneins. Genetic and acquired defects in the motors cause disease by preventing developing cells from migrating to their necessary destinations before birth or by p...

Discovery of agile molecular motors could aid in treating motor neuron diseases

...f Nature Cell Biology. The proteins in this motor, dynein and dynactin, are the "long-distance truckers" of the cell: working together, they are responsible for transporting cellular cargo from the periphery of a cell toward its nucleus. "My lab concentrates on the cellular and genetic aspects of the dyn...

UNC scientists solve mystery of how largest cellular motor protein powers movement

... helps solve a scientific mystery: how the protein dynein fuels itself to perform cellular functions vital t...comprehensive and detailed molecular structure for dynein has kept scientists largely in the dark about how the protein converts ATP into mechanical force, sa...