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Supercomputers to focus brains on AIDS dilemma
...ced early deaths. Structural biology and molecular dynamics computer simulations played an important role in t...ssibilities flow out of a long series of molecular dynamics simulations by McCammon's group. These simulations have focused on the catalytic domain of HIV-1 int...Basis for DNA ejection from single phage particles
...nd with a resolution time of 750 milliseconds) the dynamics of DNA ejection from single phages. The ejected DNA was measured at different stages of the ejection process after being stretched by applied hydrodynamic flow. The study demonstrated that DNA release is not an all-or-none process, but rather is unex...Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
...te course at Scripps--that analyzed the underlying dynamics responsible for major shifts in biological and phy...odeled by traditional statistical approaches. "The dynamics are the same during warm and cold periods, thus they are not true regimes," said Sugihara of the Phy...Insects, viruses could hold key for better human teamwork in disasters
...e researchers hope to advance understanding of the dynamics of communication and knowledge networks among first responders is by "'learning' basic principles on how bees and ants are able to effectively self-organize based on local information," said Contractor, who directs the Science of Networks in Communit......spread of rabies depends on predicting the spatial dynamics of the disease - where new outbreaks might occur a...h DL, Childs JE, Real LA (2005) Predictive spatial dynamics and strategic planning for raccoon rabies emergence in Ohio. PLoS Biol 3(3): e88. ...Scientists identify genes responsible for 'black rot' disease in vegetables
...t that these findings highlight the role of genome dynamics in the evolution of pathogenicity in Xcc in response to different host species. ...Virologists make major step towards understanding the process of HIV infection
...sential step towards a better understanding of the dynamics of HIV infection. The task of the Deutsches Krebsforschungszentrum in Heidelberg (German Cancer Research Center, DKFZ) is to systematically investigate the mechanisms of cancer development and to identify cancer risk factors. The results of this bas...New Species of Coral Discovered Off Southern California
...sential step towards a better understanding of the dynamics of HIV infection. The task of the Deutsches Krebsforschungszentrum in Heidelberg (German Cancer Research Center, DKFZ) is to systematically investigate the mechanisms of cancer development and to identify cancer risk factors. The results of this bas...Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
...ed, for the first time, evidence of the remarkable dynamics responsible for the formation of zooplankton aggregations. The new findings indicate that zooplankton are passively drifting with the current, as their name implies ("planktos" translates to "drifting" in Greek), but only in the horizontal direction,...Space matters: Estimating species diversity in the fossil record
...plines may offer valuable insights into ecological dynamics through time. Citation: Barnosky AD, Carrasco MA, Davis EB (2005) The impact of the species-area relationship on estimates of paleodiversity. PLoS Biol 3(8): e266. ...New Scripps Oceanography project to study sediments and ecosystem restoration in Venice lagoon
...ill provide valuable data about the lagoon and the dynamics involved in sediment movement. The SIOSED team will be part of a Scripps-Venice working group that will include scientists from Scripps, Thetis, the National Research Council Institute of Marine Science of Venice and the Marine Biology Laboratory of...Scientists devise way to measure RNA synthesis on the fly in a live cell
...es, "one cannot detect in real time the underlying dynamics of RNA synthesis associated with cellular activities," he said. But the scientists in his laboratory have found a way around this with a technique called fluorescence correlation spectroscopy (FCS). First, they use an RNA molecule that will bind to ...Discovering an ecosystem beneath a collapsed Antarctic ice shelf
... evidence for researchers to better understand the dynamics within the inhospitable sub-ice setting, which covers more than 1.5 million square kilometers [nearly 580,000 square miles] of seafloor, or an area of the same magnitude as the Amazon basin in Brazil or the Sahara Desert. The ecosystem, known as a "c...Envisat and ERS-2 reveal hidden side of Hurricane Rita
.... "The most detailed information about hurricane dynamics and characteristics are obtained from dedicated flights by hurricane hunter aircraft," explains Hans Graber of CSTARS. "However these flight missions cannot always take place. Satellite remote sensing provides a critical alternative approach. "It i...Proposal would allow wild animals to roam North America
...nd grizzly bears in the United States, the species dynamics shifted. The loss of wolves and grizzlies allowed elk populations to soar. Elk, in turn, ate willows, a favorite food of beavers. As a result, along winter elk ranges in Colorado, beaver populations have declined by 80 to 90 percent. With fewer beave...Traditional models underestimate extinction rates
...ted, the need to accurately predict the population dynamics and extinction risk of potentially endangered species has never been greater. In a new study, John Drake tests models traditionally used to estimate the likelihood of extinction and shows that because they ignore a critical parameter in projecting ri...Brain networks change according to cognitive task
...arest and most convincing evidence to date" of the dynamics in effective connectivity. To better understand dynamic effective connectivity, Mesulam compares the brain networks to a network of highways connecting different parts of a city. The highway is static. No matter how heavy the traffic load, it always...Scientists must offer solutions for conserving tropical forests in a rapidly changing world
...that a massive reorganization of the structure and dynamics of tropical forests is already underway" writes ecologist S. Joseph Wright, "The tropics support over half of all species and over two-thirds of all people. Without an appropriate commitment from the scientific community, the two are unlikely to cont...A new window into structural plasticity in the adult visual cortex
...g--but few have focused on the possible structural dynamics of a range of different neuron types. Surprisingly, the only neurons they saw growing were the so-called interneurons, which contain the neurotransmitter GABA and inhibit the activity of cortical neurons. The pyramidal neurons showed no structural...Computer models aid understanding of antibody-dependent enhancement in spread of dengue fever
...n more extinctions of the enhanced virus. "Dengue dynamics are similar to predator-prey systems in ecology. Antibody-dependent enhancement makes a virus a better predator. But there comes a point where the predator gets so good it runs out of prey," explained lead author Derek Cummings, a research associate ...MIT researcher finds neuron growth in adult brain
...logy that allows monitoring of neuronal structural dynamics in the living brain, they found evidence for adult neuronal restructuring in the less-known, less-accessible inhibitory interneurons. "Maybe the inhibitory network is where the capacity is for large-scale changes," Nedivi said. "What's more, this gr...Membrane research opens window to benefits for plants, humans
...linois at Urbana-Champaign used advanced molecular dynamics simulations to study the mechanics of how such proteins respond to cellular signals such as altering pH (acidity and alkalinity) or phosphorylation, a common cellular chemical process that controls protein activity. Surprisingly, the simulations cle...Free-energy theory borne out in large-scale protein folding
...ally and verify experimentally the protein-folding dynamics of a large, complex protein. The interdisciplinary research appears this week in two back-to-back papers in the Proceedings of the National Academy of Sciences. "Researchers have successfully combined computer modeling and experimental results in f...Telling axons where to go - and grow
...gradation pathway in the regulation of local actin dynamics in neurons. The authors are able to show that th...cones of hippocampal neurons. LIMK1 regulates the dynamics of the actin cytoskeleton primarily via phosphorylation of the actin depolymerization factors ADF/co...T-rays: New imaging technology spotlighted by American Chemical Society
... mail, and help researchers understand the complex dynamics involved in protein folding. Schmuttenmaer's research uses THz technology to determine characteristics of photo-excited reactions, information that cannot be acquired with any other technique. "We have also devised a system that captures the THz pu...Cortex matures faster in youth with highest IQ
... explained Rapoport. "Rather, IQ is related to the dynamics of cortex maturation."The observed differences are consistent with findings from functional magnetic resonance imaging, showing that levels of activation in prefrontal areas correlates with IQ, note the researchers. They suggest that the prolonged th...New discovery: Molecular variation in one gene affects the growth of natural populations
...lso show that the structure of the habitat and the dynamics of the species in a fragmented habitat maintain va... According to previously held views, populations dynamics in natural populations is mainly influenced by environmental factors and demography, that is birth r...Computers to save unique type of American red squirrel
...S, the new computer model, which mimics population dynamics in response to different threats, will help evaluate and refocus existing efforts to save Mount Graham Red Squirrel. Although conservation measures are already in place, concerns about the animal's viability have increased as numbers have more than ...Scientist uses dragonflies to better understand flight
...presented her research on flying systems and fluid dynamics today (Feb. 19) at the annual meeting of the American Association for the Advancement of Science. In a seminar "Falling Paper, Dragonfly Flight and Making a Virtual Insect," she said the best way to learn about flight is by first looking at what happ...Diverse tropical forests defy metabolic ecology models
... the CTFS team. Are tropical forest structure and dynamics too complex for universal explanations? "When you walk through different tropical forests, or graph data from different forests, there are certain features that, at first glance, look similar everywhere '" the presence of some very large trees, or t...The Amazon in 2050: Implementing the law could save a million square kilometers of rainforest
...is, where his teaching interests include ecosystem dynamics and modeling and digital cartography, and director of the Universidade's Center for Remote Sensing. He is also a Visiting Scientist at the Woods Hole Research Center. He earned his doctorate in Spatial Analysis from the Universidade de São Paulo in 1......ne that's central to understanding the origins and dynamics of humans unique propensity for speech. Now a McGill University psychologist believes she's separated out the complicating effects of the uterine sound barrier. And the results, says Dr. Athena Vouloumanos, point to a genetic predilection for listeni...Treating populations infected with HIV and latent TB could speed the emergence of drug-resistant TB
...ventive therapy (IPT) programs on the transmission dynamics of drug-resistant TB in areas where community-wide preventive therapy may be used as a strategy to control TB. They concluded that the implementation of IPT targeted to people co-infected with HIV and TB may also have the perverse effect of speeding ...Sea coral's trick helps scientists tag proteins
...w possibilities for studying protein and organelle dynamics in living cells, cell migration during embryogenesis, inflammation, and other pathological and normal processes," he said. Unlike other green-to-red fluorescent markers, Dendra can be activated by visible blue light, which is less harmful to living ...A new focus for the mechanism of nerve growth
...nt in living cells. They used FSM to monitor actin dynamics in nerve cells treated with a new drug called blebbistatin, that relaxes non-muscle myosin II and effectively blocks processes such as cell division. "Past research has focused on how actin structures are assembled at the leading edges of motile ce...High resolution 'snapshots' detail dynamics of a cocaine antibody
...tion and provided a rare glimpse of the structural dynamics involved. With this information, it's possible to move onto the next step in the development of a treatment for cocaine abuse and addiction." ...Climate change drives widespread amphibian extinctions
...e, the study reveals how the warming may alter the dynamics of a skin fungus that is fatal to amphibians. The climate-driven fungal disease, the author's say, has hundreds of species around the world teetering on the brink of extinction or has already pushed them into the abyss. "Disease is the bullet that's...Computer simulation hints at new HIV drug target
...s as possible targets for drug design." Molecular dynamics simulations have already proved their value in steering drug design, McCammon said. "They helped in the discovery of the current HIV protease inhibitors, which bind to the active site of the enzyme. They were also key to the development of potential ...Major WHO study concludes calcium supplements can reduce complications during pregnancy
...s as possible targets for drug design." Molecular dynamics simulations have already proved their value in steering drug design, McCammon said. "They helped in the discovery of the current HIV protease inhibitors, which bind to the active site of the enzyme. They were also key to the development of potential ...Paleontologists learn how not to become a fossil
...aid, producing a clearer picture of the biological dynamics of the past. "The gauntlet is down: look at other...ons, producing a clearer picture of the biological dynamics of the past." ......ence the terrestrial plant community and ecosystem dynamics through one particular route," state the researchers in their study. The experiment The Aleutian archipelago has over 450 islands in the highly productive North Pacific Ocean and Bering Sea. In the harsh northern climate, the islands are covere...Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers
... involved in regulating crypt stem cell population dynamics and contribute to the stem cell origin of colon cancer," Boman said. "Our finding of a difference between miRNA expression in normal versus cancerous colon tissues should provide insight into mechanisms of colon cancer development and identify nov...AIDS-related cognitive impairment exists in two separate forms
... involved in regulating crypt stem cell population dynamics and contribute to the stem cell origin of colon cancer," Boman said. "Our finding of a difference between miRNA expression in normal versus cancerous colon tissues should provide insight into mechanisms of colon cancer development and identify nov...Avian flu modeled on supercomputer, explores vaccine and isolation options for thwarting a pandemic
...celebrated Scalable Parallel Short-range Molecular dynamics (SPaSM) large-scale simulation platform developed for the nuclear weapons program. It runs on the Los Alamos supercomputer known as Pink, a 1,024-node (2,048 processor) LinuxBIOS/BProc "Science Appliance" running Clustermatic 3, the largest single-sy...In a technical tour de force, Salk scientists take a global view of the epigenome
...e effort will be scaled up to learn more about the dynamics of the whole human genome. The approach developed by Ecker and collaborators may allow researchers to do just that. "We fit the whole Arabidopsis genome - about 120 million bases - on a single high density microarray," says Ecker. "To look at the e...Atmospheric ozone recovering in mid-latitudes, report shows
...itely increasing because of changes in atmospheric dynamics and transport not related to the Montreal Protocol," he added."But we don't know the long-term effect this change will have in this region." Other recent studies complement these new findings. Among them are a study published in 2003 in the Journal ...'Micro-boxes' of water used to study single molecules
...d may enable easier experiments on single molecule dynamics and perhaps lead to the development of molecule-sorting devices that might be used for medical screening or biotechnology research. The work was reported in the July 3 issue of Applied Physics Letters. The NIST team creates the boxes by briefly shak...Researchers uncover new mechanism of tumor suppressor
...three-dimensional atomic-resolution structures and dynamics of proteins to better understand their physiological functions and relevance to diseases. ...Recombination protein dynamics observed with single monomer resolution
...nd dissociating at the trailing end. To study the dynamics of RecA, the researchers used a highly sensitive single-molecule fluorescence resonance energy transfer (FRET) technique that Ha and colleagues developed. To use FRET, researchers first attach two dye molecules ?one green and one red ?to the molecul...New light microscope sharpens scientists' focus
...ng at the molecular level secrets of intracellular dynamics that are unattainable by other methods," observed Davidson, who directs the optical microscopy division at FSU. The researchers also acknowledge that the time needed to collect the thousands of single molecule images that go into each PALM picture...What's nature worth? New computer models tell all
...ill give a sophisticated portrait of the ecosystem dynamics and value for any spot on earth. "Land use planners, county commissioners, investment bankers, anyone who is interested," Cosntanza said, "will be able to go on the Web, use our new models, and be able to identify a territory and start getting answ...Higher risk for cervical cancer seen among women infected with multiple HPV types
...ct of the newly approved vaccine, Gardasil, on the dynamics of HPV infection. "Women who harbor multiple infections are at higher risk for cervical lesions than those ever infected with one type only and should be followed more closely," said Eduardo L. Franco, Dr.PH., leader of the study and professor of e...Ring-like formations in drying DNA drops could affect hybridization studies
...phenomenon, Wong's team experimentally studied the dynamics of drying DNA droplets on glass surfaces. They report their findings in a paper accepted for publication in the journal Physical Review Letters, and posted on its Web site. "As the droplet evaporated, DNA chains were transported outward by water flo...Potato blight pathogenicity explained by genome plasticity
...y be a waste of time and resources when the genome dynamics of the pathogen population is not understood," says Govers. "Monitoring field populations of plant pathogens at the genome level will be instrumental for predicting the durability of R genes in crop plants." ...A new view on Lyme disease: Rodents hold the key to annual risk
...ations in climate and white-tailed deer population dynamics as determinants of tick abundance and disease risk. But few have investigated the impacts of fluctuations in the abundance of hosts for larval ticks, and none have examined all of these variables--temperature, precipitation, deer, mice, chipmunks, an...Adults who go to bed lonely get stress hormone boost next morning
...re look at the physiological, social and emotional dynamics of day-to-day experiences in real-life settings sh...entury look at how biological, social and cultural dynamics intersect and affect health throughout the life span. Cortisol is often characterized as a negati...Finding the right mix: A biomaterial blend library
...ct with the films. In the body, such cell-material dynamics are critically important to the outcome--determining whether a biomaterial leads to inflammation or abnormal cell growth, for example. The new study represents an innovative line of research. Working with NJCB, NIST scientists have developed a met...Stormy days ahead for coral reefs
...ver, to really predict how these events impact the dynamics of coral reefs we needed a way to quantify these vulnerabilities." "Our study offers a solution to this longstanding problem by factoring in the shape of different coral colonies, the strength of the sea-bed to which they attach and the change ...... and pollen.? Fragmentation is also changing the dynamics and structure of the forest. Tree communities in fragments are highly unstable, losing and gaining species at a high rate. Fragments also tend to lose many of their large trees and become dominated by small, fast-growing species. Forest fragme......ver, to really predict how these events impact the dynamics of coral reefs we needed a way to quantify these vulnerabilities." The authors created the world's first engineering model to predict how much damage a reef is likely to suffer when confronted with the might of an angry sea. They used mathematica...Other ContentssepticsepticsepticsepticseptumserologyserologyironironironironironironironironcalciumcalciumcalciumcalciumcalciumcalciumcalciumcalciumcalciumphosphorusphosphorusphosphorusphosphorusphosphorusphosphoruseducationeducationeducationeducationeducationeducationeducationeducationOther TagsBridgesgoalcomponentsGapGapGapGapPlanPlanPlanPlanPlanPlanPlanPlanreceivereceivereceivereceiveprofessionalswerewerewerelibrariesresponses
(Date:5/16/2008)... data show that CAPHOSOL ( www.caphosol.com ), an ...al mucositis (OM) and improves quality of life for...tion therapy. These data will be reported in two ...m presentation and one tomorrow as a poster sessio...sing Society (ONS). These data confirm that CAPHOS...
(Date:5/16/2008)...in biomechanics and physiology from six universiti...s Institute of Technologys Media Lab, refute scien...torius, a 21-year-old South African bilateral ampu...ntage in the 400-meter race. Their conclusions wer...ocomotion Laboratory, under the direction of Profe...
(Date:5/15/2008)...chers has developed a simple artificial cell with ... of two of the most basic cell components: the cel... that surrounds the structures in living cells. T...at take advantage of properties of cell organizati...am,s findings will be published later this month (...
(Date:5/15/2008)...ave improved the power output of one type of fuel ...at could help these environmentally friendly energ...icularly in portable electronics. , The new mate...ensive than its conventional industrial counterpar...ace traditional fuel-cell membranes with these cos...
Breaking Biology News(10 mins):CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 2CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 3CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients 4Breaking news: Study revives Olympic prospects for amputee sprinter 2Breaking news: Study revives Olympic prospects for amputee sprinter 3Simple model cell is key to understanding cell complexity 2MIT creates new material for fuel cells 2MIT creates new material for fuel cells 3Frequent alcohol consumption increases cancer risk in older women 790 1Frequent alcohol consumption increases cancer risk in older women 790 2Good Clinical Practice Journal Awards 3A Winners Announced 785 1Good Clinical Practice Journal Awards 3A Winners Announced 785 2Good Clinical Practice Journal Awards 3A Winners Announced 785 3Good Clinical Practice Journal Awards 3A Winners Announced 785 4Richard Schulz Receives the Coveted GCPj Award for Best Clinical Researcher of the Year 438 1Richard Schulz Receives the Coveted GCPj Award for Best Clinical Researcher of the Year 438 2New AHIP Report Takes a Ten Year Look at the Unintended Consequences of State Efforts to Change the Insurance Market 778 1New AHIP Report Takes a Ten Year Look at the Unintended Consequences of State Efforts to Change the Insurance Market 778 2(Date:5/16/2008)...ffices of Howard G. Smith,announces a June 9, 2008...ecurities class action lawsuit filed on behalf of ...e common stock of Inverness Medical,Innovations, I... IMA ) in the,Company,s secondary public offering .... The shareholder lawsuit is pending in the United...
(Date:5/16/2008)...s want agency to act, not wait years , ,...umer drug ads on television should include a toll-...port adverse side effects, U.S. health experts sug...hat advises the U.S. Food and Drug Administration....A for print ads. At Friday,s meeting, the panel di...
(Date:5/16/2008)...HINGTON, May 16 /PRNewswire-USNewswire/ -- More th...s in the Greater Portland, Oregon and,Vancouver, W...ract as,Teamsters., "The Teamsters are pleased th...act that gives them job protection and a secure re... Jim Hoffa., The workers, both full-time and part...
(Date:5/16/2008)...fit from calcitriol, an oral form , , FR...vitamin D may cut the risk of death for people wit...ut one quarter, a new study suggests. , During...se being treated with calcitriol, an oral form of ...th lowered by 26 percent when compared with those ...
Breaking Medicine News(10 mins):Health News:Law Offices of Howard G. Smith Announces 24 Days Remaining to Move to Be a Lead Plaintiff in the Shareholder Lawsuit Against Inverness Medical Innovations, Inc. 2Health News:FDA Panel Considers Toll-Free Number for TV Drug Ads 2Health News:FDA Panel Considers Toll-Free Number for TV Drug Ads 3Health News:Vitamin D Use Linked to Lower Mortality in Kidney Patients 2[0] Law Offices of Howard G. Smith Announces 24 Days Remaining to Move to Be a Lead Plaintiff in the Shareholder Lawsuit Against Inverness Medical Innovations, Inc.[0] FDA Panel Considers Toll-Free Number for TV Drug Ads[0] Paramedics, EMTs in Oregon, Washington State Ratify First-Ever Teamsters Contract[0] Vitamin D Use Linked to Lower Mortality in Kidney Patients
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