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Nano-Probes Allow an Inside Look at Cell Nuclei

...ally compact cadmium selenide/zinc sulfide quantum dot coated with silica. Next, they stole a trick from a virus's playbook to smuggle this nanocrystal past the highly selective membrane that guards the entrance into the nucleus. In nature, a virus called SV40 is coated with a protein that binds to a cel...

Nanoparticles offer new hope for detection and treatment

...articles are a few thousand times smaller than the dot above this "i," yet each can carry about 100,000 molecules of the metal used to provide contrast in MRI images. This creates a high density of contrast agent, and when the particles bind to a specific area, that site glows brightly in MRI scans. In ...

Young Blood Revives Aging Muscles, Stanford Researchers Find

...alled satellite cells, the muscle stem cells, that dot muscle tissue. These normally lie dormant but come to the rescue in response to damaged muscle-at least they do in young mice and humans. In older mice the satellite cells hold the same position, but are deaf to the muscle's cry for help. In the Nat...

Tagging pathogens with synthetic DNA 'barcodes'

...the color codes of individual beads. Another is by dot blotting, in which the sample is spread on a sheet of absorbent paper and made visible to the naked eye. Or the color can be observed directly through a fluorescent light microscope, which is useful in situations where the geographic distribution of ...

Quantum dots provide a faster, more sensitive method for detecting respiratory viral infections

...ilt researchers report that not only can a quantum dot system detect the presence of particles of the res...esearchers' next step will be to develop a quantum dot cocktail capable of simultaneously detecting the presence of at least five major respiratory viruses...

New technique may speed DNA analysis

...ss chip printed with up to 500,000 tiny dots. Each dot comprises multiple DNA molecules of known sequence, i.e. a piece of an individual's genetic code. Scientists use DNA microarrays to discover and analyze a person's DNA or messenger-RNA genetic code. This allows for, say, the early diagnosis of liver ...

New technique helps identify multiple DNA regulatory sites

...ss chip printed with up to 500,000 tiny dots. Each dot comprises multiple DNA molecules of known sequence, i.e. a piece of an individual's genetic code. Scientists use DNA microarrays to discover and analyze a person's DNA or messenger-RNA genetic code. This allows for, say, the early diagnosis of liver ...

Out of sight, out of mind? Not necessarily

... horizontal or a vertical line or a red or a green dot flashed on the screen. Researchers then asked the...participants had to guess whether a red or a green dot had flashed on the screen, they gave the correct answer with 81 percent accuracy. "This high degree...

Method slashes quantum dot costs by 80 percent

...d of replacing the pricey solvents used in quantum dot synthesis with cheaper oils that are commonplace a... than a year ago on the scale-up issues of quantum dot manufacture, but the solvents turned out to be so expensive that we just couldn't afford to run more...

The right drug at the right time

...d of replacing the pricey solvents used in quantum dot synthesis with cheaper oils that are commonplace a... than a year ago on the scale-up issues of quantum dot manufacture, but the solvents turned out to be so expensive that we just couldn't afford to run more...

'Smart' nanoprobes light up disease

...olves tethering a gold nanoparticle to the quantum dot to inhibit luminescence. The tether, a peptide seq...holds the gold close enough to prevent the quantum dot from giving off its light. In their test system, the Rice team used a peptide tether that is cleave...

New nanosensor uses quantum dots to detect DNA

...researchers shined a laser on the mix, the quantum dot passed the energy on to the Cy5 molecule that was ...inctive glow would not have appeared. Each quantum dot can connect to up to about 60 DNA sequences, making the combined glow even brighter and easier to se...

Study may help slay 'Yellow Monster'

...mental exposure to uranium from mine tailings that dot the landscape across the Navajo Nation. "When the uranium mining boom crashed in the '80s, it really crashed and there wasn't much cleanup," Stearns said. Estimates put the number of abandoned mines on the Navajo Nation at more than 1,100. NAU sen...

Pathway toward gene silencing described in plants

...t a brilliant signal in the nucleolus, a brilliant dot in the same place for each of the proteins," said ...ontes also found that the siRNAs were in that same dot within the nucleolus. Pontes and Pikaard were able to deduce the order of events by studying mutati...

Math model predicts cancer behavior

Vito Quaranta clicks on a small black dot on his computer screen. The dot ?which represents about a thousand cancer cells ?begins to "grow," morphing into a mass with finger-...