Abnormal brain circuits may prevent movement disorder
... who carry a genetic mutation for a movement disorder
called dystonia will never develop symptoms, a ... carriers are protected from symptoms of the disorder
they have an additional lesion that evens the ... mutation carriers have a characteristic circuit disorder
involving a motor system that is revved up and ...
'Normal' cells far from cancer give nanosignals of trouble
... the health of cells by measuring the increase in disorder
-- the structural variations -- within the cell. ... The cancer cells showed an increase in structural disorder
on the nanoscale.
For each organ, the ... looked normal. PWS, however, detected a level of disorder
in the cell architecture that was much closer to ...
Chemical in blood may explain susceptibility to bladder pain
... species' susceptibility for a painful bladder disorder
called interstitial cystitis, a condition that is ... method is very sensitive and specific for the disorder
in both humans and domestic cats. So far it ... is some kind of primary central nervous system disorder
that results in problems in the bladder in some ...
History of hyperactivity off-base, says researcher
... Carleton University this week, that hyperactivity disorder
as we understand it today is a modern construct that was first described as a disorder
Before that, Smith says hyperactive ... existed but it wasn't always thought of as a disorder
or pathology worth treating.
However, Smith ...
Genetic study confirms the immune system's role in narcolepsy
... identified a gene associated with narcolepsy, a disorder
that causes disabling daytime sleepiness, sleep ... best evidence for autoimmunity as a cause of the disorder
was the discovery that nearly everyone with the disorder
has unique variants of a gene called ...
2 genes influence social behavior, visual-spatial performance in people with Williams syndrome
... of two genes,GTF2I and GTF2IRD, in a rare genetic disorder
known as Williams Syndrome.
Their results, ... Collaborating on the behavioral aspects of this disorder
has been Ursula Bellugi, professor and director ... one or more genes that most people with the disorder
"I wanted to focus on something ...
Statins may treat blood vessel disorder that can lead to fatal strokes
... researchers have shown that a blood vessel disorder
leading to unpredictable, sometimes fatal, ... for cerebral cavernous malformation (CCM), a disorder
with no known drug therapy, according to U of U ... to join a pilot trial of statins.
CCM is a disorder
in which blood vessels in the brain become ...
Mayo Clinic: Brain disorder suggests common mechanism may underlie many neurodegenerative diseases
... in profound depression and parkinsonism in a disorder
known as Perry syndrome. Although this syndrome ... have been generally regarded as byproducts of the disorder
rather than the cause, the researchers say. These ... gene, even though families afflicted with this disorder
are unrelated, and come from different ....
MU researcher identifies possible genetic causes of borderline personality disorder
... of Mental Health, borderline personality disorder
(BPD) is more common than schizophrenia or bipolar disorder
and is estimated to affect 2 percent of the ... on chromosome nine was linked to BPD features, a disorder
characterized by pervasive instability in moods, ...
M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan
... but targeted treatments that may reverse this disorder
are currently being tested at the MIND Institute. ... can cause attention deficit hyperactivity disorder
(ADHD) and autism spectrum disorder
in children; primary ovarian failure (early ...
NARSAD announces 2008 Prizes for Outstanding Achievement in Research on Mental Health Disorders
... research in the areas of schizophrenia, bipolar disorder
and depression, childhood disorders and cognitive ... Europe, whose groundbreaking research on conduct disorder
and attention deficit hyperactivity disorder
has led to new understanding of these conditions ...
Largest study of its kind implicates gene abnormalities in bipolar disorder
... genetic analysis of its kind to date for bipolar disorder
has implicated machinery involved in the balance ... of Health, found an association between the disorder
and variation in two genes that make components ... of drugs used to clinically to treat bipolar disorder
Although it's not yet known ...
Study finds connections between genetics, brain activity and preference
... risk of suicidal thinking in major depressive disorder
patients soon after beginning antidepressant ... current study had no evidence of any psychiatric disorder
or physical disorder
that might influence brain activity.
Hebrew University develops novel approach for treating mitochondrial disorders
... to a genetic mutation, a mitochondrial metabolic disorder
occurs. Modern medicine offers no cure for ... of DERT by treating the mitochondrial disorder
lipoamide dehydrogenase (LAD) deficiency. LAD ... now being conducted on the in-vivo model of this disorder
in LAD-deficient mice. Very promising preliminary ...
At Boston symposium, NARSAD researchers report on genes and family traits
... illnesses, such as schizophrenia, bipolar disorder
Presented at NARSAD's 3rd ... to and pathology of schizophrenia, bipolar disorder
and depression, some of the most severe, chronic ...
"Schizophrenia is a prevalent and costly disorder
and can be very difficult to treat. This is ...
Gene mutations in mice mimic human-like sleep disorder, UT Southwestern researchers find
... involved in sleep create a human-like insomnia disorder
in mice, UT Southwestern Medical Center ... may help scientists better understand the disorder
and provide an animal model for developing ... appeared to have a condition similar to a human disorder
called sleep maintenance insomnia, in which ...
Adolescent girls with ADHD are at increased risk for eating disorders, study shows
... Girls with attention deficit hyperactivity disorder
stand a substantially greater risk of developing ... the Journal of Abnormal Psychology.
ADHD is a disorder
that affects about 5 percent of school-age ... serious problems making friends.
Because the disorder
is far more common in boys, researchers are still ...
Europe's most common genetic disease is a liver disorder
... The exact origin of the genetic iron overload disorder
hereditary hemochromatosis (HH) has remained ... in the current issue of Cell Metabolism that the disorder
develops when a crucial gene is lacking in liver ... Hereditary hemochromatosis is an iron overload disorder
that, affecting about one in 300 people, is ...
RNA interference therapy heals growth deficiency disorder in a live animal
... called RNA interference, can heal a genetic disorder
in a live animal.
The study, which was published ... figure out the underlying cause of this genetic disorder
and then identify a way to prevent it, says John ... it has been used to correct a dominant negative disorder
in a living animal, says Patton.
The researchers ...
New studies on schizophrenia, depression, trauma and autism highlight annual meeting
... Helpful in Treating Post-Traumatic Stress disorder
in Early Stages When treated within a month, ... with early symptoms of post-traumatic stress disorder
(PTSD) following a traumatic event that had ... on areas of the brain that contribute to bipolar disorder
or schizophrenia in youth, according to new ...
Mental disorders are disorders of the brain
... Depression, anxiety disorders such as panic disorder
and obsessive-compulsive disorders,
alcohol and ... has been suffering from at least
one mental disorder
in the past 12 months, such as depression, ... dependence, social phobia,
generalized anxiety disorder
(GAD), bipolar disorder, psychotic disorders, ...
Restless legs syndrome affects nearly 2 percent of US/UK children
... legs syndrome (RLS) is a neurological sleep disorder
characterized by sensations in the legs that ... sleep. Some people with periodic limb movement disorder
also have RLS. Others lack the sensations in the ... such as attention deficit hyperactivity disorder
and depression appear to be more common in those ...
Little-known protein found to be key player
... that a little-understood protein previously implicated in a rare genetic disorder
plays an unexpected and critical role in building and maintaining healthy ... a better understanding of hereditary spastic paraplegia (HSP), the genetic disorder
that atlastin has been linked with," Daga said.
HSP is a rare genetic ...
UAB study reveals bone coupling factor key to skeletal health
... Camurati-Engelmann disease, and many more, all involve a bone coupling disorder
to some degree."
Previous research has hinted at but failed to explain ... fellow researchers studied mice with Camurati-Engelmann disease, a genetic disorder
that causes haphazard bone formation and poor skeletal health. They found ...
UF makes gene therapy advance in severe genetic disorder
... of Florida putting scientists a step closer to finding a cure for the disorder
Called glycogen storage disease type 1A, the genetic ... better treatments for the glycogen storage disease is crucial because the disorder
is still associated with multiple complications, and care remains a ...
Capturing the birth of a synapse
... may lead to new therapies or a cure for autism, a brain development disorder
that affects a person's social and communication abilities. The disorder
affects 1 in every 150 American children, according to the Autism Society ...
New light on bipolar treatment drugs
... better understanding Lithium, we can learn about the genetics of bipolar disorder
and develop more potent and selective drugs.
"Further, altered PIP3 ... is currently under clinical trial for the treatment of neurogenerative disorder
amyotrophic lateral sclerosis (ALS)
The research, funded by the ...
Frogs reveal clues about the effects of alcohol during development
... Fetal alcohol spectrum disorder
(FASD) and Fetal alcohol syndrome (FAS) cause malformations in babies, ... and maturation cues during development.
Fetal alcohol spectrum disorder
(FASD) and Fetal alcohol syndrome (FAS) cause malformations in babies, ...
Fetal alcohol syndrome testing expands
... tests that help identify and assess children with Fetal Alcohol Spectrum disorder
"Our initial study was carried out with a relatively small ... of Neurosciences, Mental Health and Addiction. "Fetal Alcohol Spectrum disorder
is a significant health issue in Canada. The work of Dr Reynolds and his ...
New potential therapeutic target discovered for genetic disorder -- Barth syndrome
... Syndrome (BTHS). BTHS, a sometimes fatal disease, is a serious genetic disorder
occurring predominantly in males that leads to infection or heart failure ... resulting in muscle weakness and fatigue in patients. The debilitating disorder
is caused by a mutation in the genetic coding of tafazzin, an enzyme of ...
Airborne asthma allergens
... since the latter part of the twentieth century. It is a chronic breathing disorder
with both genetic and environmental factors influencing symptoms and no ... no studies have so far investigated the particularly high incidence of the disorder
there in an integrated way.
The team sampled air from eleven ...
USC researchers identify gene variant associated with both autism and gastrointestinal dysfunction
... Pediatrics and is now available online.
Autism is a developmental disorder
characterized by deficits in communication abilities, social behavior ... say.
"Gastrointestinal disorders don't cause autism. Autism is a disorder
of brain development," Levitt says. "However, our study is the first to ...
A revolutionary new model for Alzheimer's disease
... new model for Alzheimer's disease (AD), a devastating neurodegenerative disorder
which afflicts 24 million people worldwide. In an effort to unravel the ... that collect in the brain this research points to the condition as a disorder
involving an imbalance in signaling between neurons. The study appears ...
Mayo Clinic researchers suspect a novel gene is causing restless legs syndrome in a large family
... in Florida, diagnosed restless legs syndrome. This common neurologic disorder
interrupts sleep because of unpleasant sensations in the legs at rest, ... is one of the largest with restless legs syndrome ever studied, and the disorder
spans multiple generations. Therefore, the gene linked to the syndrome is ...
MUHC and McGill scientists explain genetic disease first discovered in Quebec 24 years ago
... completes a 24 year-old hunt for the cause of an incredibly rare genetic disorder
called, cblF combined homocystinuria and methylmalonic aciduria ... how it behaves in healthy cells."
The cblF idisease is a rare genetic disorder
characterized by an inability to metabolize vitamin B12. Patients ...
Studies examine genetic determinants of ADHD
... the latest progress in genetic research of Attention Deficit/Hyperactivity disorder
(ADHD). The issue covers major trends in the field of complex psychiatric ... disorders, researchers have been searching for genes that underlie the disorder
in the hopes that gene discovery will lead to better treatments for the ...
'Deranged calcium signaling' contributes to neurological disorder, UT Southwestern researchers find
... in nerve cells may play a major role in a fatal genetic neurological disorder
that resembles Huntington's disease, researchers at UT Southwestern ... ataxia 3 also known as SCA3, or Machado-Joseph disease is a genetic disorder
that, like Huntington's, impairs coordination, speech, and vision and ...
Bipolar disorder genes, pathways identified by Indiana University neuroscientists
... from the latest large-scale international gene hunting studies for bipolar disorder
with information from their own studies and have identified the best ... is most likely what made past attempts to identify genes for the disorder
through genetic-only studies so difficult and inconsistent."
Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
... issue of Molecular Cell , have implications in understanding the human disorder
In mammals the cells contain two copies of ... be silenced.
This mechanism is important for understanding the genetic disorder
Beckwith-Wiedemann Syndrome. In this condition silencing of the chromosome ...
Seemingly suicidal stunt is normal rite of passage for immune cells
... scientists' understanding of ataxia telangiectasia, a rare genetic disorder
that, among other symptoms, can weaken the immune system. Patients with the disorder
have a mutation in a gene, ATM, that normally helps the cell sense DNA ...