Dementia in Biological News

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

... illness and neurological disorders, especially dementia and Parkinsons disease. By 2040, Alzheimers ... from depression, and over 5 million people have dementia (about 1.1𔂿.3% of the population). The ... as anxiety, mania, depression, schizophrenia, dementia or neurological and addictive disorders in the ...

Is vitamin D deficiency linked to Alzheimer's disease and vascular dementia?

... of which are either considered risk factors for dementia or have preceded incidence of dementia. In 2008, ... Dr. Grant suggests that studies of incidence of dementia with respect to prediagnostic serum 25(OH)D or ... D in reducing the risk of diseases linked to dementia such as vascular and metabolic diseases, as well ...

Early identification of dementia increasingly difficult

... predict which elderly individuals risk developing dementia do not seem to work any longer. The thesis shows ... In addition, it is more difficult to predict dementia the higher the person's level of education', says ... the link between forgetfulness and future dementia is more complex than commonly thought. Memory ...

Blood test predicts chance of dementia

... Frontal lobe dementia Frontal lobe dementia (Frontotemporal Dementia, FTD) strikes people at ... After Alzheimer's disease, FTD is the form of dementia that occurs most frequently in patients younger ...

NYU Langone Medical Center's tip sheet to the International Conference on Alzheimer's Disease 2008

... of the ill spouses was in the early stages of dementia and could still participate in a counseling ... were surprised by how much the person with dementia could communicate in the session. They also ... cognitive decline to mild cognitive impairment or dementia compared to adults without initial complaints. ...

1/3 of risk for dementia attributable to small vessel disease, autopsy study shows

... decline and dementia, 45 percent of the risk for dementia was associated with pathologic changes of Alzheimer's disease. Another 10 percent of dementia risk was associated with Lewy bodies, neocortical ... Parkinson's disease. But a third of the risk for dementia (33 percent) was associated with damage to the ...

HIV is a 'double hit' to the brain

... responsible for the neurodegeneration and dementia seen in people infected with HIV, the findings ... down has helped to reduce the severity of the dementia in recent years. Nonetheless, the prevalence is ... that we might eventually treat this form of dementia by either ramping up brain repair or protecting ...

A 'heart healthy' diet and ongoing, moderate physical activity may protect against cognitive decline

... closely people adhered to the DASH diet and risk of cognitive decline and dementia among older participants in the Cache County Study on Memory, Health and ... with no history of breast cancer, HRT use, psychiatric disorder, dementia or other neurological condition. Participants gave details on the amount ...

Results from trials of DHA in Alzheimer's disease and age-related cognitive decline

... assessment scale-cognitive (ADAS-cog) and rate of change on Clinical dementia Scale-sum of the boxes (CDR-SOB). These two measures are the current ... not slow the rate of change on tests of mental function (ADAS-cog), global dementia severity status (CDR-SOB), activities of daily living (ADL), or behavioral ...

Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time

... Extensive death of nerve cells leads to severe dementia in patients with Alzheimer's disease. Until now, it has only been possible ... search for drugs that can stop the extensive cell death, and thereby stop dementia in patients," says Haass. "The first findings have already shown that we ...

Mayo Clinic: Brain disorder suggests common mechanism may underlie many neurodegenerative diseases

... disorders, the researchers say. In Alzheimer's disease, frontotemporal dementia and progressive supranuclear palsy, for instance, the "spikes," comprised ... a protein known as TDP-43 which is found in patients with frontotemporal dementia or with motor neuron disease. What these clumps represent is not known, ...

Where optics meets medicine

... caused by venule occlusions, are often seen in autopsies of people who had dementia late in life, says Nguyen, and now researchers have a way to study this ... In the last decade, autopsies have revealed that people with the worst dementia often don't have the worst plaques, and clots and hemorrhages in small ...

£2 million study to reveal workings of dementia genes

... are to investigate the biological causes of the second most common form of dementia after Alzheimer's, thanks to a prestigious 1.9 million senior fellowship ... can develop problems with grammar and pronunciation or have semantic dementia where they lose the information content of language. Errors in two ...

Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain

... lateral sclerosis, Huntingtons disease, epilepsy, stroke/ischemia, dementia and malignant gliomas RICHMOND, Va. (May 9, 2008) Virginia ... to treat Alzheimers disease, Huntingtons disease, epilepsy, stroke, dementia and malignant gliomas. Neurodegenerative diseases are caused by the ...

High cholesterol in your 40s increases risk of Alzheimer's disease

... conclusions regarding high mid-life cholesterol and the risk of vascular dementia were difficult to formulate as there are several types of vascular dementia that may have slightly different risk factors. ...

New clinical data shows chromium picolinate improves cognitive function

... and insulin resistance have been linked to age-related cognitive decline, dementia and Alzheimers disease. These findings suggest that improving glucose ... (15.7 versus 15 years), stage and extent of memory impairment (Clinical dementia Rating sum boxes score, 1.0 versus 0.85) or level of mood disturbance ...

Lipids in the brain an important factor for Alzheimer's disease?

... Brussels & Leuven, Belgium As the most common form of dementia in the Western world, Alzheimer's disease carries enormous implications ... explain that these symptoms are comparable with those of early stage dementia in humans. Producing protofibrils for new applications in medicine ...

Story ideas from Molecular & Cellular Proteomics

... function deteriorates over time, including AD, Parkinsons disease with dementia (PDD), and dementia with Lewy body (DLB) disease, and frontotemporal lobar degeneration ....

AIDS interferes with stem cells in the brain

... (La Jolla, CA August 15, 2007) A prominent problem in AIDS is a form of dementia that robs ones ability to concentrate and perform normal movements. ... strain bred to express HIV/gp120 in its brain. This mouse model for AIDS dementia mimics several features of the disease process found in humans. They ...

Cell's split personality is a major discovery into neurological diseases

... (CNS). Diseases that occur as a result of high glutamate levels include hypoxicischemic brain injury (stroke), trauma, seizures, various forms of dementia and neurodegeneration. For years, the main explanation for the toxic effects of glutamate is that it overexcites neuronal cells via activation of ...

Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants

... protein interaction that suppresses neural cell formation in the brains of mice, and that might be relevant to Alzheimer's, the most common form of dementia among older people. "In this project, we will investigate whether this protein interaction also occurs in human stem cells and in the adult ...

Tiny but toxic: MBL researchers discover a mechanism of neurodegeneration in Alzheimer's disease

... but with the loss of functional connections. It's when the neuron is no longer talking to its targets that you start to get the memory deficits and dementia associated with the disease," Brady says. The amyloid beta particles activate an enzyme, CK2, which in turn disrupts the "fast axonal transport" ...

New target for medicine to combat Alzheimer's: VIB scientists confirm protein's key role

... Alzheimer's disease Two thirds of all patients with dementia suffer from Alzheimer's disease. Estimates indicate that by 2010 our country will have more than 150,000 Alzheimer's patients. Alzheimer's is a ...

New research findings may enable earlier diagnosis of uterine cancer

... in the cell, but excess amounts, which can damage the cell and the body's DNA, are associated with over 200 diseases, from arteriosclerosis and dementia to rheumatism, cerebral haemorrhage and cancer. The studies carried out by Sandra Karlsson on human malignant tumours have confirmed that changes in ...

Scientists make strides toward defining genetic signature of Alzheimer's disease

... Scientists have new information about the complex genetic signature associated with Alzheimer's disease, the leading cause of cognitive decline and dementia in the elderly. The research, published by Cell Press in the January issue of the American Journal of Human Genetics , uses a powerful, ...

Impaired energy metabolism linked with initiation of plaques in Alzheimer's brain

... and disease-modifying therapies for AD, especially those aimed at interrupting pathological Aβ-production. AD, the leading cause of dementia in the elderly, is a devastating neurological disorder characterized by accumulation and deposition of sticky clumps of A? protein. A? protein is ...

Epilepsy drug shows potential for Alzheimer's treatment

... hope colleagues will be able to progress this research with clinical trials in the near future." Alzheimer's disease is the most common form of dementia and has no cure. In the UK today there a half a million people living with Alzheimer's and this is likely to double within a generation unless new ...

M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan

... of the fragile X gene can cause, among other disorders, autism and ADHD in children, anxiety disorders at all ages, early menopause in women and dementia in the elderly. Because the potential impact is so great, M.I.N.D. Institute researchers have created an inexpensive spot blood test for newborn ...

2 Alexander von Humboldt professorships go to LMU Munich

... Gene Center in Munich intend to explain the principles of gene regulation in higher cells and organisms, which will give fresh impetus to cancer and dementia research as well as the development of stem cell therapies. The head of the Gene Center, Professor Patrick Cramer, is especially delighted that, with ...

70 years old and going strong with Down syndrome and no dementia

... a new benchmark and tremendous hope for all people with Down Syndrome to live longer and healthier lives." The processes regulating aging and dementia are complex and it is unlikely that any single mechanism can fully explain the array of changes that occur with aging. While future research could ...

Researchers link cocoa flavanols to improved brain blood flow

... long-term improvements in brain blood flow could impact cognitive behavior, offering future potential for debilitating brain conditions including dementia and stroke. In a scientific study of healthy, older adults ages 59 to 83, Harvard medical scientists found that study participants who regularly ...

Scientists learn how food affects the brain

... Folate supplementation, either by itself or in conjunction with other B vitamins, has been shown to be effective in preventing cognitive decline and dementia during aging and enhancing the effects of antidepressants. The results of a recent randomized clinical trial indicate that a three-year folic acid ...

Can tomatoes carry the cure for Alzheimer's?

... is a promising first step towards finding an edible vaccine against the neurodegenerative disease. Alzheimer's disease is the most common cause of dementia and it progresses over a long period of time. It is thought to be caused by the accumulation of human beta-amyloid, a toxic insoluble fibrous protein ...

Known genetic risk for Alzheimer's in whites also places blacks at risk

... studies have failed to detect the effect of the APOE epsilon 4 allele on cognitive decline among blacks. In addition, false-positive rates for dementia on standardized screening tests are higher for blacks than for whites when compared to neurologists' ratings of cognitive status, Sachs-Ericsson ...

New technology may prevent vitamin B12 deficient seniors and vegetarians from needing injections

... may soon exist. According to the National Institutes of Health, vitamin B12 deficiency can lead to a wide spectrum of conditions, such as anemia, dementia and reduced cognitive functioning. Vitamin B12 deficiency is a significant health issue. Nearly 40 percent of the U.S. population is B12 deficient ...

First diagnostic test for Alzheimer's and Parkinson's disease on the horizon

... as being helpful in making a diagnosis. Susan Sorensen, head of research at the UK Alzheimers Society said: There are 700,000 people living with dementia in the UK, 62 per cent have Alzheimers disease and this will rise to more than a million in less than 20 years. An effective blood test would present ...

Selective restraints and reduced medication could reduce nursing home falls says 4-year study

... 743 males and 1,908 females ranging from 40 to 105 years of age, with an average age of 72. All had been diagnosed with a physical illness or dementia and some suffered from both. The researchers found that people using certain drugs were much more likely to experience a fall. Sleeping pills ...

Highlights from the December 2007 Journal of the American Dietetic Association

... Infants of Immigrant Mothers Poor Nutrient Intakes over a One-Year Follow-Up in Community-Dwelling Older Adults with Early-Stage Alzheimer dementia Compared to Cognitively Intact Matched Controls About Feeding Children: Mealtimes in Childcare Centers in Four Western States Emergency ...

A novel way found to prevent protein plaques implicated in Alzheimer's

... to therapy, said Ralph A. Nixon, M.D., Ph.D., Professor of Psychiatry and Cell Biology at NYU School of Medicine and Director of the Center for dementia Research at the Nathan S. Kline Institute. Dr. Nixon also directs the Silberstein Institute at NYU School of Medicine. Given the increasing ...

An Alzheimer's vaccine?

... encourage imaginative researchers to test unconventional strategies, as Dr. Tang has done here. We face an overwhelming epidemic of Alzheimer's and dementia if we don't change the current unsatisfactory situation by greatly improving early detection, treatment and prevention. ...