daily

Controversial drug shown to act on brain protein to cut alcohol use

...mption. They inducedthe rats to consume alcohol in daily drinking sessions and thendemonstrated that their ...alcohol to rats until theyhad become "experienced" daily drinkers. They then withheld alcohol fortwo weeks, which normally leads to greatly increased drinkin...

Scientists rid stem cell culture of key animal cells

...to grow and sustain stem cells through the tedious daily task of generating mouse feeder cells from mouse e...ells," says Xu. "It also significantly reduces the daily labor of preparing the feeder cell-conditioned medium." "It is important that the culture of human ...

Ophthalmologists Use Artificial Silicon Retina Microchip To Treat Vision Loss

...ents have experienced improvement in activities of daily living such as improved ambulation-not bumping into objects around the house, and reading the time on a clock." Still in Phase II clinical trials, Pollack cautions it is still too early to determine what percentage of patients might experience impro...

Unprecedented water level rise in Somalia

...ility of the population around the city, affecting daily activities such as commuting to work, school and accessing hospitals and markets. The floods affected at least 170 households. ...

Ophthalmologists implant five patients with artificial silicon retina microchip

...ents have experienced improvement in activities of daily living such as improved ambulation-not bumping into objects around the house, and reading the time on a clock." Still in Phase II clinical trials, Pollack cautions it is still too early to determine what percentage of patients might experience impro...

Artifical cornea lets woman blind 20 years see

...which is why every patient must adhere to a strict daily regimen of antibiotic eye drops. With regular maintenance ?including visits to the ophthalmologist at least every three months (more frequently immediately after surgery) ?complications can be kept to a minimum, she said. Because of the intensiveness...

Discovery clarifies role of peptide in biological clock

...eded by the brain's biological clock to coordinate daily rhythms in behavior and physiology. Neurons in the...d later and later on subsequent days so that their daily activity patterns were splitting apart." Herzog and Aton recorded neuron activity from the SCN usin...

Innovative collaboration brings Arctic science into the classroom

...uring their expedition, Holmes and Clapp will have daily communications with students and the public, using a satellite phone hooked to a laptop computer for internet communications. According to Holmes, "Getting kids excited about science is the most important thing. If they realize that science is an exc...

Characterizing Skin Cancer by Microarrays

...ademy of Sciences. Founded in 1914, PNAS publishes daily online and weekly in print. The preceding highlights are not intended to substitute for articles as sources of information. The articles in PNAS report original research by independent authors and do not necessarily represent the views of the Nationa...

Newly discovered protein an important tool for sleeping sickness research

... 36 countries of sub-Saharan Africa are threatened daily by a deadly parasitic disease known as African sleeping sickness. The disease is caused by organisms called trypanosomes, which are spread by the tsetse fly. African sleeping sickness affects approximately 500,000 people in sub-Saharan Africa, a quar...

Breakthrough System for Understanding Ocean Plant Life Announced

... 36 countries of sub-Saharan Africa are threatened daily by a deadly parasitic disease known as African sleeping sickness. The disease is caused by organisms called trypanosomes, which are spread by the tsetse fly. African sleeping sickness affects approximately 500,000 people in sub-Saharan Africa, a quar...

Researchers Identify Cause of Early Bird Sleep Disorder

...othered by living out of sync with everyone else's daily schedule. "Some of them would never come to a doctor" to find out what's going on with their sleep pattern, Ptacek said, "because they aren't troubled by it. Often, they have adjusted and accommodated their jobs to match their ability. But others ar...

Searching the depths of the straits of Florida for disease cures

... as deep as 3,000 feet. The team will also conduct daily scuba dives in search of shallow-water organisms for biomedical testing. Though Harbor Branch has used its submersibles to explore the Bahamas extensively since the 1970s, this will be the institution's first trip to Cay Sal. Almost no information i...

Best research work in the area of wine growing

...deficit in each plant was assessed by means of the daily measurement of the hydric potential before dawn and, when a plant reached the stress interval, it was irrigated immediately. After two or four days after the recovery irrigation, the gaseous interchange was measured, comparing it with plants that had...

Does vitamin C help prevent or treat the common cold? Maybe not, after all.

...the last 65 years. All of these studies compared a daily dose of 200mg of vitamin C or more against a dummy pill (placebo). Did vitamin C given for prevention reduce the risk of picking up a cold? The authors looked at 23 studies done in the general population, using doses of up to 2g daily, and found tha...

Late peak may have prevented severe flu season from becoming worse

...rrent of their kind. In the 2004-2005 flu season, daily CAP discharges peaked at an average of about 7,000 and 8,000, respectively, in January/February 2005 compared to the previous flu season's December 2003/January 2004 peak. Both these seasons had approximately 31 percent more hospital discharges than ...

New protein vital for immune response is found in surprise location

... was best known for generating energy required for daily life. "This is the first mitochondrial protein known to be involved in immune defense against any microbial infection," said Dr. Zhijian "James" Chen, associate professor of molecular biology at UT Southwestern and the study's senior author. "This d...

New type of rejection blocker protects kidneys after transplant

...ith a collection of medications that must be taken daily to prevent rejection by suppressing the immune system's hostile response to a transplanted organ, Vincenti said he expects his patients to receive an injected immune tolerance treatment a few times a year -- and perhaps to be able to stop taking anti...

Female volunteers prepare for a second 'bedrest'

...es in regular exercise sessions. In another group, daily meals were accompanied by a dietary supplement (certain amino acids which form the basis of proteins). Volunteers needed for phase 2 For phase 2 of the study, which is due to begin in September, ESA, the French space agency CNES and the MEDES Insti...

UNC computer, marine scientists collaborate to predict flow of toxic waters from Katrina

...nd other weather factors. Their goal is to provide daily forecasts of coastal circulation and pollutant concentrations in the Katrina-affected region, information that will be vital as cleanup efforts and recovery continue. The two also have extended their work with RENCI, Reed and colleagues to analyze v...

Virologist finds contagious equine flu in dogs

...gs have the most intimate contact with humans on a daily basis, so the potential for human infection has to be in the back of our minds," said Ed Dubovi, director of the virology center at Cornell's Animal Health Diagnostic Laboratory, who isolated the virus from the University of Florida samples. Still,...

Temperature regulates circadian clock in zebrafish

...pond to light cycles, much less is known about how daily temperature cycles affect the clock's timing mechanism in vertebrates. In the open-access journal PLoS Biology , Kajori Lahiri, Nicholas Foulkes, and their colleagues study temperature related responses at the genetic and molecular level in zebrafi...

Seaweed could make junk food healthier

...uit and vegetables, yet to consume the recommended daily amount of fibre they would have to eat a lot of these types of foods. "We believe it's hard to change people's habits and that the most practical solution is to improve the food they do eat. With a burger, for example, you would simply remove some ...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

...provement in the UPDRS score. Also, activities of daily living (ADL), another standard measure of Parkinson's severity which is recorded by the patients themselves, showed a strong trend toward statistical improvement(p= .06). In addition, fluorodeoxyglucose (FDG)-PET scans at one year revealed that the ...

Pollution-eating bacteria produce electricity

... things that we tend not to think about during our daily routines. When we do, thoughts on bacteria usually do not enter our minds. Bacteria make you sick, they are important in the processing of food, but making electricity? Surely that is not part of the story. But it is," says Milliken. ...

Scientists uncover new clues about brain function in human behavior

...people's social behavior through the monitoring of daily life events such as danger signals. Scientists know from animal studies that damage to the amygdala impairs social functioning. "Social interactions are central to human experience and well-being, and are adversely affected in psychiatric illness. T...

Methamphetamine Abuse, HIV Infection Cause Changes in Brain Structure

...rformance, and problems with general activities of daily living, such as managing money,?says Dr. Jernigan. “The impact of methamphetamine on daily functioning is less well studied, although it is known that abusers of the drug have impaired decisi...

Infectious disease expert warns of spread of Rocky Mountain spotted fever

...ent for adults, he says, involves immediate, twice daily 100-milligram doses of the oral antibiotic doxycycline (a version of the common tetracycline) until the patient's fever subsides. Patients continue to take the medication for an additional five days to prevent the disease from rebounding. Infected ch...

NASA satellite data provides rapid analysis of Amazon deforestation

...aerosols. These impacts are further minimized with daily composites created through the combination of individual images. While high resolution imagery is still needed when estimating the total area of deforestation or when identifying small clearings, "the most exciting finding of this study is that it s...

Bone marrow stem cells may heal hearts even years after heart attacks

...art attack damage, reduce symptoms and improve the daily functioning of patients; it might also reduce the risk of heart failure, Dr. Strauer said. Current heart attack interventions attempt to restore blood flow to the heart muscle as soon as possible, in order to limit the amount of permanent scarring. ...

Many smokers fail to quit after cancer diagnosis

...had significantly worse physical and psychological daily functioning. Clinical guidelines for generalized smoking cessation intervention strategies from the U.S. Department of Health and Human Services are available, but the diagnosis of cancer presents complex physical and emotional challenges to applyin...

Plants reveal a secret and bring researchers nearer a cleaner future

...r away are we then from using the sun to power our daily lives? Michael Haumann, the main author of the publication, asserts that "these are important results that will make an impact in the photosynthesis community. They help our understanding of how solar energy is used in plants and contribute to the ef...

Restaurant seafood prices since 1850s help plot marine harvests through history

...t walked the earth and remains a vital item in the daily diet of millions worldwide," says Danish environmental historian Poul Holm, who leads the HMAP network of researchers and institutions. "The Romans ate fish in vast quantities. And over-fishing in medieval Europe was a very real problem in the days ...

Health benefits of a Christmas brandy

...d give the equivalent antioxidant potential to the daily recommended intake of vitamin C. "The antioxidants only make up only a small percentage of substances found in brandy, but they are a very important part of the mix. "So when you are enjoying a slice of brandy-infused fruit cake or a drink of good ...

Deep treasure to be found in Oculina Bank

...athering samples. Team members will also be filing daily dispatches from the ship at www.at-sea.org. One of the expedition's goals is to "ground truth," or verify, a newly produced high-resolution multibeam sonar map of the region, which offers unprecedented resolution to reveal bottom features that were ...

Penn Surgeons Use Completely Robotic Surgery to Successfully Treat Prostate Cancer

...nd reduced recovery period for a quicker return to daily activities. The actual robot consists of a tower that manipulates instruments controlled from a console that is situated a few feet from the patient. At the console, the surgeon operates four robotic “arms?and “wrists?using hand and foot controls. ...

Scientists learn to predict protein-stabilizing ability of small molecules

...nd reduced recovery period for a quicker return to daily activities. The actual robot consists of a tower that manipulates instruments controlled from a console that is situated a few feet from the patient. At the console, the surgeon operates four robotic “arms?and “wrists?using hand and foot controls. ...

Clocking in Pillow Time without the Pillow

...it weighs you down. For people without time for a daily eight hours in the sack, drugs that counteract the effects of sleep deprivation could serve as substitutes. In a new study, Sam Deadwyler and colleagues have explored this possibility by giving dog-tired rhesus monkeys a drug shown to improve the fun...

Noise And Delays Explain Why Some Genes Oscillate In Activity

...it weighs you down. For people without time for a daily eight hours in the sack, drugs that counteract the effects of sleep deprivation could serve as substitutes. In a new study, Sam Deadwyler and colleagues have explored this possibility by giving dog-tired rhesus monkeys a drug shown to improve the fun...

WWF peeks into mysterious life of Borneo's pygmy elephants

...d with a collar that can send GPS locations to WWF daily via satellite. Now, for the first time, the public can track the movements of the elephants online through an interactive web map at www.worldwildlife.org/borneomap . "No one has ever studied pygmy elephants before, so everything we're learning is ...

A resetting signal keeps circadian rhythm on track in Drosophila fruit flies

...ns coherence among brain clock cells that regulate daily activity of Drosophila melanogaster (fruit flies)....into darkness for extended periods of time. This daily resetting signal flows from the morning to the evening cells and maintains a 12-hour difference betw...

Depression model leaves mice with molecular scar

...xposed to aggression by a different dominant mouse daily for 10 days became socially defeated; they vigorously avoided other mice, even weeks later. Expression of a representative gene in the hippocampus, a memory hub implicated in depression, plummeted three-fold and remained suppressed for weeks. However...

Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

...randomly assigned to receive by injection either a daily dose of 10 µg/kg of G-CSF or placebo (an inactive substance) for 5 days. The patients were treated between February 2004 and February 2005. Treatment with G-CSF produced a significant mobilization of bone marrow stem cells. The researchers found tha...

H5N1 avian flu virus vaccine induces immune responses in healthy adults

...an avian flu pandemic looms large, say experts, as daily reports indicate an increasing spread of infection in bird populations in Southeast Asia, Europe, the Middle East and Africa. According to the World Health Organization, as of March 24, 2006, 186 people had been infected with avian flu viruses, and m...

Tiny polyps gorge themselves to survive coral bleaching

... "In most cases, corals get 100 percent of their daily metabolic energy needs from the algae. Once they are gone, the coral polyp is left with only two alternatives: Draw energy from stored fats within its body, or eat organic matter and plankton in the surrounding water," she said. But what has puzzle...

Alcoholism, smoking and genetics among Plains American Indians

...patterns," she said. "In societies where regular, daily drinking is the norm, such as in Europe, anxious Met individuals may be more vulnerable to alcoholism through using alcohol as a coping mechanism. In societies where heavy, periodic drinking bouts are the norm, such as in some American Indian tribes...

Researchers reverse juvenile diabetes in animal model

...igue. People with type 1 diabetes require numerous daily injections of insulin to survive. About Dr. Trucco Massimo Trucco, MD, has dedicated his life's work to finding a cure for diabetes -- finding a cure is a personal quest for him. As an international leader in the field of immunogenetics, Dr. Tru...

Human albumin from tobacco plants

...dministration in operating theatres being almost a daily occurrence. It is used for haemorrhages, burns, surgical operations or when the patient shows symptoms of malnutrition or dehydration, chronic infections and renal or liver illnesses. The annual consumption in Spain is about 10 tons but, at a worldwi...

There's something fishy about human brain evolution

...ain consumes an amazing 75-per cent of an infant's daily energy needs. According to Dr. Cunnane, to fuel this neural demand, human babies are born with a built-in energy reservoir ?that cute baby fat. Human infants are the only primate babies born with excess fat. It accounts for about 14 per cent of their...

Antioxidant selenium offers no heart-disease protection

...ake a tablet containing 200 micrograms of selenium daily or a placebo. Information on sociodemographics, health habits, education and body mass index also was collected. Participants provided blood samples at their respective clinics twice a year and reported any new illnesses or medications. Individuals...

Study finds drug may cut down involuntary movements

...rea, however, tetrabenazine can help activities of daily living, and improve functional capacity," Shannon said. "If the drug is approved, physicians will need to work carefully with patients and caregivers to find the appropriate dose. Side effects were seen in about 25% of subjects in the study. The...

Clock molecule's sensitivity to lithium sheds light on bipolar disorder

...rol of metabolism because feeding behavior is on a daily cycle, and hormonal activities that regulate this are circadian," says senior author Mitch Lazar, MD, PhD, Director of the Institute for Diabetes, Obesity, and Metabolism at Penn. "Many studies, including those here at Penn, suggest a relationship be...

Butterflies lose body fat during metamorphosis

...pus, on which the butterfly lays its eggs. On a daily basis, they measured the food consumption of the larva and then analyzed the fatty acid composition and content of the diet as well as the larva. Once the larva had transformed into butterflies, the researchers examined the fatty acid composition an...

Patients now surviving once-fatal immune disease

...ever, these problems did not interfere with normal daily activities, and the quality of life in this group was equivalent to that of the general male population of the United States," said Vanessa Howard, R.N., M.S.N., a nurse practitioner for the Immunology service at St. Jude and first author of the pape...

Common enzyme is a key player in DNA repair

... to the undergraduate classroom. DNA is assaulted daily by toxic chemicals, metabolic byproducts, sunlight, and other forms of radiation. Most of the nicks and dings are quickly fixed by the cell's fleet of precision DNA repair processes, which can surgically excise and replace a faulty section. But some...

Deep-rooted plants have much greater impact on climate than experts thought

...e might behave," Lee said. Lee accounted both for daily and seasonal dryness in the Amazon, and showed that the two together have a large impact on the climate over the region. The increased moisture in the soil created by hydraulic redistribution during the dry season allows the plant to carry on photosy...

It's in the genes: Study opens door to new treatment of the blues

... the experiment, the researchers subjected mice to daily bouts of social threats and subordination by aggressive rodents and continuous sensory contact with the aggressors for 10 days. Afterward, the defeated mice avoided any social contact by spending most of their time in the corner of their cages opposi...

Intensive statin therapy may partially reverse plaque build-up in arteries

...r ultrasound (IVUS) examination and received 40 mg daily of rosuvastatin (brand name Crestor®). IVUS provides a precise and reproducible method for determining the change in plaque, or atheroma, burden during treatment. Atherosclerosis progression was assessed at baseline and after at 24 months of treatme...

Mice lacking social memory molecule take bullying in stride

...first subjected mice to a different dominant mouse daily for 10 days. Even 4 weeks later, the "socially defeated" animals vigorously avoided former aggressors or unfamiliar mice. BDNF and an indicator of gene expression increased markedly in their social memory circuit. Yet, the social avoidance behavior w...

Resveratrol prolongs lifespan and delays onset of aging-related traits in a short-lived vertebrate

...ogical decay. The researchers added resveratrol to daily fish food and found that this treatment increased longevity and also retarded the onset of aging-related decays in memory and muscular performance. Resveratrol appears to be the first molecule to consistently cause life extension across very differ...