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Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine

...at didn't die, with the slow rise in leukemia cell count seen in patients due to an accumulation of these immature and incompetent white blood cells. Scientists have since discovered that CLL cells do indeed turn over, with the accumulation over time a result of the difference in the birth and death rates ...

The very unexpected life and death of a leukemic cell

...born at a slow rate, causing the slow rise in cell count over time. But researchers had been unable to find... rate and do indeed die. The slow rise in the cell count over time can be attributed to the difference between the birth and death rates of the cells, accord...

Nano-bumps could help repair clogged blood vessels

...the discs were washed and a microscope was used to count how many of the dyed cells adhered to the material. The researchers found that nearly three times as many cells stuck to the discs containing the nano-bumps, as compared to ordinary titanium. "After one hour, we get three times more endothelial cell...

Scientists journey to southern Africa to unravel the secret world of elephant communication

...ention to the wildlife below. "I try to get a good count of the elephants as they come in and a good view w...a remote census technique using geophone arrays to count elephants and other animals. The research team discovered that the footfall of a large animal produc...

Comprehensive biodefense text published

...support for possible acts of bioterrorism, medical count ermeasures, emerging threats and future preparation, and development of diagnostic tests for identifying biological warfare pathogens. Intended for researchers, physicians, and policy makers, Biological Weapons Defense: Infectious Disease and Counte...

TrueBlue Archive Will Store Raw Life Sciences Data for Proteomics and Drug Testing

...support for possible acts of bioterrorism, medical count ermeasures, emerging threats and future preparation, and development of diagnostic tests for identifying biological warfare pathogens. Intended for researchers, physicians, and policy makers, Biological Weapons Defense: Infectious Disease and Counte...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...ulation. It returned with a slightly reduced death count about once a generation for centuries. Although far less common now, the plague has not entirely gone away. There are fewer than 2,000 cases a year worldwide, including 10 to 20 each year in the western United States. One out of seven persons infect...

Newest HIV drugs should be used with FUZEON(R)

...fe. Getting back to undetectable and seeing my CD4 count increase from 20 to 268 has changed my outlook on life. I believe I can plan for the future, which I didn't even consider doing before starting this regimen. I have much more energy now than I had before, which is exhilarating since I have been held ...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...that work to keep an individual's white blood cell count at normal levels during chemotherapy. After that,...hen tested in mice, increased the white blood cell count for three days, whereas the injectable agents only maintain effectiveness for one day," Shen says. "...

Using computers and DNA to count bacteria

... in this week's Science Magazine with a new way to count bugs in dirt. Bacteria, that is, in the highly complex world beneath our feet. "Computational Improvements Reveal Great Bacterial Diversity and High Metal Toxicity in Soil," by Jason Gans, Murray Wolinsky and John Dunbar, of Los Alamos' Bioscience D...

Comparison of Cocaine, Methamphetamine ‘Highs?Finds Differences

... in this week's Science Magazine with a new way to count bugs in dirt. Bacteria, that is, in the highly complex world beneath our feet. "Computational Improvements Reveal Great Bacterial Diversity and High Metal Toxicity in Soil," by Jason Gans, Murray Wolinsky and John Dunbar, of Los Alamos' Bioscience D...

Six previously blind patients detect light, motion, identify objects with retinal prostheses

... months-were able to "localize the position of, or count the number of, high contrast objects with 74 to 99 percent accuracy," Humayun says. In addition, they could discriminate simple shapes-i.e., figure out the spatial orientation of a bar or the capital letter L-with 61 to 80 percent accuracy. The rese...

Siberian tigers hang tough

...e, say the coordinators of a 2005 winter effort to count the animals, led by the New York-based Wildlife Co...ey represents the most extensive effort to date to count tigers in Russia. Tiger conservationists around the world were buoyed by these results, especially ...

Say what? Bacterial conversation stoppers

...rum sensing, bacteria converse among themselves to count their numbers and to get the population to act in unison. A synchronized group of bacteria can mimic the power of a multi-cellular organism, ready to face challenges too daunting for an individual microbe going it alone. Swelling populations trigger ...

HIV Therapy Greatly Extends Life of Key T Cells, Scientists Find

...cell DNA at each time point, the researchers could count how many new cells were made and how long they lived. The scientists found a marked increase in the numbers of newly made CD4+ cells in all the HIV-positive, IL-2 responsive volunteers. In two HIV-positive volunteers ?each of whom had received multi...

Color perception is not in the eye of the beholder: It's in the brain

...by our eyes. "We were able to precisely image and count the color-receptive cones in a living human eye for the first time, and we were astonished at the results," says David Williams, Allyn Professor of Medical Optics and director of the Center for Visual Science. "We've shown that color perception goes ...

Cheap, rapid hand-held check for HIV

... definitions of AIDS say that once a person's CD4+ count falls below 200 cells per microlitre of blood, he or she has developed the condition. Doctors rely on CD4+ measurements to decide when to start drug treatments and to gauge whether a patient is responding to them. To make the device, researchers ...

Oops! Researchers publish new findings on the brain's response to costly mistakes

...nded in healthy individuals when we made the error count more." The new research confirms previous U-M studies using a different brain-activity monitoring technique and led by senior author William Gehring, Ph.D., Arthur F. Thurnau Professor of Psychology in the U-M College of Literature, Science, and the...

Measuring artery repair cells could become new heart disease test

... sample, then culture the remaining cells and then count individual of EPC colonies that grow. The new system permits researchers to gauge the number of EPCs based by identifying those cells with a high amount of ALDH activity. The Duke researchers based their studies on analysis of blood samples taken fr...

Molecular mechanism may explain how fevers spark seizures

... and counting the cars on the street: it's easy to count how many are there at any time, but if we want to know where they all came from and where they're all going, that's a whole different problem." The team's discovery that high temperature reduces cell surface GABA-A receptor levels "raises the idea ...

The diversity of marine life in the Gulf of Maine region is much greater than previously thought

... Andrews, New Brunswick, announced today the first count of known marine species in the Gulf of Maine regio...re than 50% larger than previous estimates. The count is 3,317 species and includes both year-round species and those that migrate to the region seasonall...

New study shows benefit of early therapy in HIV-infected infants

...mmune status. They call this age-adjusted CD4 cell count the "z-score." Based on data collected over the p... to attain a 20 percent increase in their CD4 cell count z-score at any time, compared to children who started treatment before 5 months." However, the auth...

Scientist-astronaut sends T-cells into space

...hich suppresses them. When an HIV patient's T-cell count falls below 200, he or she is susceptible to the dangerous infections that are the symptoms of acquired immunodeficiency syndrome (AIDS). The problem of immunosuppression in microgravity was first noted during the Apollo moon mission series in the...

'Micro-boxes' of water used to study single molecules

...ght emissions over several seconds are analyzed to count the molecules and observe other phenomena. The researchers use two sets of optical tweezers to move droplets together to fuse them and mix their contents (see accompanying video). The team demonstrated the technique by trapping and manipulating dropl...

How HIV 'exhausts' killer T cells

... higher the patient's viral load and the lower the count of helper T cells, said Walker. When they co... diagnostic tool, said Walker. "Currently, we just count the number of helper T cells to decide when to treat someone, but we are excited about the possibili...

A new tool against brain disease

... higher the patient's viral load and the lower the count of helper T cells, said Walker. When they co... diagnostic tool, said Walker. "Currently, we just count the number of helper T cells to decide when to treat someone, but we are excited about the possibili...

How healthy is that marsh? Biologists count parasites

...project is to establish a baseline snail-trematode count in marshes, particularly those slated for restoration. By comparing worm statistics before and after a restoration project, which could include activities such as digging channels or removing non-native plants, the biologists believe that wetlands ma...

Even a little cooling helps after cardiac arrest

...project is to establish a baseline snail-trematode count in marshes, particularly those slated for restoration. By comparing worm statistics before and after a restoration project, which could include activities such as digging channels or removing non-native plants, the biologists believe that wetlands ma...

Genetic snooze button governs timing of spring flowers

... long, dark days of winter, gardeners are known to count the days until spring. Now, scientists have learned, some plants do exactly the same thing. Addressing scientists here today (Aug. 9) at a meeting of the American Society of Plant Biologists, University of Wisconsin-Madison researcher Richard Amasi...

Prevention is the best option: fighting autoimmune diseases

...veloped allows us for the first time to accurately count thenumber of regulatory T cells in the body," says Assoc Prof Fazekas. The highly accurate identification and isolation of regulatory T cells was made possible using sophisticated flow cytometry equipment at the Centenary Institute. The machines us...

With record resolution and sensitivity, tool images how life organizes in a cell membrane

...s determine the locations of specific swimmers and count how many swimmers are in the pool. What scientists really want to know is what membrane components are near what other components, how that organization changes over time and how that organization leads to the emergence of function, Boxer said. In ...

AIDS study challenges conventional treatment guidelines for HIV patients

... try to predict how quickly that person's CD4 cell count will reach the danger level at which treatment for... other groups, is to focus on both the current CD4 count and the viral load to estimate how rapidly a person's CD4 cell count will decrease. This approach is...

Study shows interruption of antiretroviral therapy increases risk of disease and death

...72 participants infected with HIV with a CD4+ cell count of more than 350 per cubic millimeter to the conti...ed only using antiretroviral therapy when the CD4+ count decreased to less than 250 per cubic millimeter and then stopping therapy when the CD4+ count increa...

Recurrence of a flu pandemic similar to infamous 1918 flu could kill 62 million

...re distributed fairly equally. A simple population count from that period would lead to the conclusion that about 20 percent of all fatalities occurred in the developed world. "But when you look at the data," said Murray, "that number shrinks to about three or four percent." The disparities between the ...

Serengeti patrols cut poaching of buffalo, elephants, rhinos

...erial surveys. It's been impossible to actually count the number of animals that are poached because poaching is illegal and most animals ?apart from elephants and rhinos which are traditionally not eaten ?are caught in snares set by local villagers for their own use or sale. A recent article in Nationa...

Gene chip technology shows potential for identifying life-threatening blood infection

...d similar - fever and an elevated white blood cell count - making it virtually impossible in many cases even for seasoned doctors to make a diagnosis based on symptoms alone. Non-infectious inflammation is common among ICU patients recovering from surgery, pancreatitis, or trauma from a car accident or fal...

First Biodiversity Census of coral reef ecosystems in the NW Hawaiian Islands

...h the diversity found in rainforests and a partial count of organisms living in a tropical aquarium." Information from this effort will be posted on the CReefs website at www.creefs.org , and the cruise can also be followed at www.hawaiianatolls.org and http://sanctuaries.noaa.gov/ . Furthermore, ...

Fast test for low blood flow in dogs detects early heart trouble

...w fast blood is flowing. Researchers can actually count the number of beads absorbed into the heart tissue to calculate blood flow. However, calculating blood flow from the 3-D, scanned CT images was more complicated. Researchers used so-called deconvolution mathematical formulae to gauge the speed of ...

Fantastic Voyage: A new nanoscale view of the biological world

... potatoes in the refrigerator of another. You can count how many there are and measure how fast they are used and replaced. It is this level of resolution and quantification that MIMS makes possible within cells." Lechene, of Harvard Medical School and Brigham and Women's Hospital in the US, worked w...

Fruit fly gene research may shed light on human disease processes

...mes are produced in each sex. Failure to properly count X chromosomes is lethal to embryos of mammals and flies. That's why biologists want to understand the process of "chromosome counting." Early in his career, Erickson was part of the research team that identified the genes involved in counting Dro...

Cornell researcher helping develop quick, cheap HIV/AIDS test

...factors -- CD4 T-cell count, or CD4+ T-lymphocytes count -- in the blood. "When patients are infected with HIV/AIDS, the number of circulating CD4 T-cells drops significantly," explains Baeumner. "If they get the appropriate retroviral treatment, their life span can be increased by many years. CD4 counts...

Common blood test can help distinguish between mononucleosis and tonsillitis

... white blood cell count. Total white blood cell count was significantly increased in the tonsillitis gro.... 11,400 cells per microliter), but the lymphocyte count was higher in the mononucleosis group (6,490 cells per microliter vs. 1,590 cells per microliter). ...

Researchers first to map gene that regulates adult stem cell growth

...d clinically, such as for ramping up the stem cell count in cancer patients undergoing chemotherapy and bone marrow transplantation. The researchers agreed that this very process is not only interesting, but important because of its usefulness in a wide variety of future genetics studies. "We'r...

Indicators for risk of heart disease are higher in passive smokers

... another inflammatory marker, and white blood cell count in participants with elevated cotinine levels. They found no significant association. The effect levels seen for fibrinogen and homocysteine were about twice as high when measuring cotinine levels compared to previous studies based on self-reporte...

No magic tomato? Study breaks link between lycopene and prostate cancer prevention

Tomatoes might be nutritious and tasty, but don’t count on them to prevent prostate cancer. In the May issue of Cancer Epidemiology, Biomarkers & Prevention, researchers based at the National Cancer Institute and Fred Hutchinson Cancer Research Center report that lycopene, an antioxidant predominatel...