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Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
...onut oils; they are associated with higher risk of coronary disease. The healthier polyunsaturated fats are those that remain liquid at room temperature, such as various types of vegetable oils. Trans-unsaturated fatty acids, or trans fats, are artificially produced solid fats used in shortening and margarin...Implanted Devices Detect High-Risk Heart Failure Patients
..., its many causes include infections of the heart, coronary artery disease, high blood pressure, previous heart attacks and valve problems. An estimated 4.7 million Americans suffer from the condition, with 400,000 new cases reported each year. Roughly one-half of patients die within five years of diagnosis. ......11 million people in the United States suffer from coronary artery disease. Many patients receive medications ...se blood flow but nearly 500,000 angioplasties and coronary bypass procedures are performed each year in those patients who do not benefit from medication. ...International HapMap consortium expands mapping effort
...For any given disease, such as type II diabetes or coronary artery disease, researchers can use the HapMap to compare the genetic variation patterns of a group of people known to have the disease with a group of people without the disease. Finding a certain pattern more often in people with the disease identi...Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
...ated 10 million people each day to protect against coronary artery disease and reduce the incidence of heart attacks--limit cholesterol synthesis by inhibiting reductase function, he said. As a result, cells take up more cholesterol from the bloodstream, lowering its concentration there. However, inhibition ...Men Estimate Men's Risks Of Common Disorders Higher Than Women Do, And Vice Versa
... health problem and health behaviour. For example, coronary heart disease tends to be perceived as a 'male disease' even though it is the leading cause of mortality amongst women in the UK. (One study found that 30 year old women with chest pain were much less likely than 30 year old men to be given a cardiac...Survival of heart patients on beta-blockers varies greatly with genetic variation
...dical Association. "In our investigation of acute coronary syndrome (ACS) patients discharged on beta-blocker therapy, we were able to associate risk of death with the characteristics of the patients' beta-adrenergic receptor genes," says co-author Howard L. McLeod, Pharm.D., professor of medicine, of geneti...Surgical Robot 'Scrubs In' At UNC, May Be More Precise Than Conventional Surgery
...valves, remove cancerous prostates, bypass blocked coronary arteries and perform gastric bypass operations for morbid obesity. The new arrival is a robotic machine, the da Vinci Surgical System, manufactured by Intuitive Surgical. UNC currently is the only gynecological oncology program in the Southeast that...Screen all at risk for HIV, plus pregnant women
...valves, remove cancerous prostates, bypass blocked coronary arteries and perform gastric bypass operations for morbid obesity. The new arrival is a robotic machine, the da Vinci Surgical System, manufactured by Intuitive Surgical. UNC currently is the only gynecological oncology program in the Southeast that...FDA: 'Highly Unlikely' Green Tea Lowers Cancer Risk
...valves, remove cancerous prostates, bypass blocked coronary arteries and perform gastric bypass operations for morbid obesity. The new arrival is a robotic machine, the da Vinci Surgical System, manufactured by Intuitive Surgical. UNC currently is the only gynecological oncology program in the Southeast that...Women feel more pain than men, research shows
...periences of pain. "Chest pain is associated with coronary heart disease, angina and heart attacks, so it is understandable that chest pain is a cause of great anxiety for patients and that anxiety has an important role in the experience of chest pain," said Dr Keogh. "This research is also consistent with ...Bone marrow stem cells may heal hearts even years after heart attacks
...and function disturbances in patients with chronic coronary artery disease after myocardial infarction, even m...he marrow were infused through a catheter into the coronary artery where the patient's heart attack occurred. "The main results were at least threefold: an imp...Smoking damages key regulatory enzyme in the lung
...eal and throat cancers; chronic lung diseases; and coronary heart and cardiovascular diseases. Fowler and her colleagues have been studying MAO for more than 30 years. The U.S. Department of Energy (DOE) Office of Biological and Environmental Research and the National Institutes of Health have provided fundi...UT Southwestern researchers unravel control of growing blood vessels
...mally ?suggesting methods of treatment for various coronary diseases. Abnormal growth of cells inside blood vessels is involved in hypertension, coronary artery disease, tumors called leiosarcomas and other conditions. "By understanding this detailed me...Feds give researchers ok for safety test of adult stem cells in patients with heart disease
...g bone marrow stem cells at varying doses into the coronary arteries of patients suffering chronic ischemic coronary artery disease, a condition in which one or more of the primary arteries supplying blood flow to the...No link found between caffeine intake and development of hypertension in women
...e article. Hypertension is a major risk factor for coronary heart disease, stroke, and congestive heart failure. Therefore, even small reductions in the prevalence of hypertension could have a potentially large public health and financial impact. Several previous studies have indicated a possible association...Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack
...ration of blood flow) to the heart by percutaneous coronary intervention (procedures such as angioplasty in wh...catheter-guided balloon is used to open a narrowed coronary artery) within 12 hours after onset of symptoms. Patients were randomly assigned to receive by injec...Researchers map of genetic variations implicated in disease
...is and, we hope, treatment of diseases such as TB, coronary heart disease, diabetes and rheumatoid arthritis." The MHC Haplotype Project is creating a public resource to assist the discovery of genetic factors influencing these medical traits and to shed light on the evolution of the MHC. Access to complete ...Antioxidant selenium offers no heart-disease protection
...m supplementation on any of the endpoints studied: coronary heart disease, stroke or deaths from cardiovascular disease, Stranges said. There also was no difference in the endpoints based on the level of selenium at baseline. In addition, the lack of significant association with CVD endpoints was confirmed ev...Ernst Mayr's theory illustrated in genetic epidemiology studies
... including his own genetic epidemiology studies of coronary artery disease (CAD). "These recent results really show that Mayr's ideas were correct," said Templeton. "His theory has been empirically supported very well." But first, the background. Mayr thought that founder events were very important in t...For one Stanford doctor, the beat goes on during open-heart surgery
...ative technique called "beating-heart" surgery for coronary bypass. It replaces the more conventional use of a heart-lung machine, which allows for stopping the heart during surgery. "It's very, very technically demanding," said Ihnken discussing the challenge of working on a still-beating heart shortly befo...Aspirin reduces cardiovascular risks in men and women -- but differently
...elded a total of 95,456 patients, none of whom had coronary artery disease. Of that total, 51,342 were women. The trials all involved the comparison of low-dose aspirin versus placebo for the primary prevention of cardiovascular disease. The analysis revealed that aspirin conferred a 12 percent reduction in ...Intensive statin therapy may partially reverse plaque build-up in arteries
...s (partially reverse) the buildup of plaque in the coronary arteries. This finding has never before been ob...ve statin therapy could prevent the progression of coronary atherosclerosis, or arterial plaque build-up, but not actually reduce disease burden. ACC.06 is the ...Measuring artery repair cells could become new heart disease test
...EPCs could be used to assess a patient's degree of coronary artery disease or risks for suffering a heart atta... that the EPC levels correlated with the degree of coronary artery disease. Patients with no coronary artery disease had about 70 percent more EPCs than those w...Nearly half of people who need cholesterol treatment don't get it
...cipant's 10-year risk of developing disease of the coronary arteries was calculated, and they were classified as being low risk, moderate risk or high risk. "We found that cholesterol disorders were common in this population that is free of known cardiovascular disease," said Goff. "And we found that choles...Bone and cartilage growth to blame for heart valve disease
...he United States population, and is second only to coronary artery disease as a cause for open heart surgery. ...can be treated with medications similar to that of coronary artery disease. "As with the majority of people in the field who hear about this research, I was su...One in 14 men having a heart attack drive themselves to hospital
...took 54 minutes longer for women to be admitted to coronary care units than men. Women also waited longer to b... Approximately 120 nurses working across the six coronary care units in Dublin, Southern Ireland, took part in the study, completing a 25-item questionnaire f...Statins have neutral effect on risk of cancer
...led trials for primary and secondary prevention of coronary artery disease. In these trials, statins reduced the risk of a first myocardial infarction (heart attack) and overall mortality. With long-term follow-up and collection of cancer data in a majority of studies, insight into the risk of cancer among...New GI technologies improve internal organ visualization
...eal punctures and interventions into the heart and coronary arteries in six pigs and two human patients. Endo...chers punctured the myocardium and aortic valve or coronary artery in the six pigs; three received angiography and three received thermal ablation, or clearing ...Adult stem cell research at UB targets damaged hearts
...ow over an extended period of time due to narrowed coronary arteries adapt to this deprivation by down-regulat... and regenerative medicine for humans with chronic coronary artery disease will lead to optimized MSC therapeutics that can be of clinical value in managing agi...New study shows antibiotic may protect the heart
...tigrowth properties, rapamycin effectively reduces coronary restonosis, the abnormal narrowing of a blood vessel. In coronary angioplasty, stents coated with rapamycin are implanted to reduce the risk of restonosis. "A signi...Reversing 'hibernating' heart muscle focus of UB researchers
...common in patients with heart failure arising from coronary artery disease, Canty noted. "Determining how this impacts prognosis is the focus of the UB Cardiovascular Center's PAREPET (Prediction of Arrhythmic Events with Positron Emission Tomography) clinical trial, which also is funded by NHLBI. "Identif...Variations in detoxifying genes linked to Lou Gehrig's disease
...ncluding Alzheimer's disease, Parkinson's disease, coronary artery disease and stroke. Although the Northwestern DNA study samples were not analyzed for inclusion of Gulf War veterans, Siddique and co-researchers found significant evidence that gene variations (polymorphisms) on the chromosome region encomp...Higher levels of obesity associated with greater health risks
...ship between weight category and risk of death and coronary heart disease (CHD) in a large population-based sample of U.S. women, focusing on risk across degree of obesity. The researchers analyzed data on incident death and cardiovascular outcomes by weight status in 90,185 women recruited from 40 U.S. cent...Clot-busting drug helps revive cardiac arrest patients
...me erratic or irregular because of a heart attack, coronary heart disease, a blood clot in the lungs, or other causes. The heart stops beating and the brain starts to suffer permanent damage within four to six minutes. Death quickly follows. The standard treatment for cardiac arrest is Advanced Cardiac Life...Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation
...us injections were found to shrink plaque in human coronary arteries. The Cedars-Sinai researchers, collaborating with researchers from Sweden, also are developing vaccine against LDL cholesterol (bad cholesterol) that one day may be administered in childhood to provide lifelong protection against vascular...Minorities, uninsured less likely to receive care at high-volume hospitals
...ncluded elective abdominal aortic aneurysm repair, coronary artery bypass grafting, carotid endarterectomy, es... lung cancer resection, cardiac valve replacement, coronary angioplasty, pancreatic cancer resection, and total knee replacement. According to this database, ...Fast test for low blood flow in dogs detects early heart trouble
...lood that has been slowed down by narrowing of the coronary arteries. Researchers say it took them less than ...ner "could dramatically change the way we diagnose coronary disease in patients with initial symptoms of chest pain, by providing a safe, non-invasive and fast ...PET imaging shows young smokers quick benefit of quitting
The early stages of coronary artery disease in young smokers can be reversed qu...ve this is the first PET study that shows abnormal coronary function is reversible after only one month of smoking cessation," said Nagara Tamaki, a professor a...Diabetes slows nerve recovery after heart transplant
...e complicated and laborious sampling of blood from coronary arteries and veins," he added. Diabetes mellitus is a chronic disease that occurs when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Such a deficiency results in increased concentratio...New study finds chocolate chip cookies lower cholesterol
...estimated 30 percent reduction in the incidence of coronary heart disease. The soluble fiber in Right Direc...able bowel syndrome, constipation, hemorrhoids and coronary artery disease. "Our results suggest dietary treatment with Right Direction Cookies significantly...Performing surgery on a beating heart may be safer
...cording to a review of the latest clinical trials, coronary artery bypass surgery performed on a beating heart, without the aid of a heart-lung machine, is a safe option that leads to fewer negative side effects for bypass patients. This review is featured in Journal of Cardiac Surgery. “Previously, it was ...100 percent juices found as beneficial to health as fruits and vegetables
...he literature states, “When considering cancer and coronary heart disease prevention, there is no evidence that pure fruit and vegetable juices are less beneficial than whole fruit and vegetables.? The researchers add that the positioning of juices as being nutritionally inferior to whole fruits and vegetable...Protein therapy may reduce infarct size in heart attack patients
...ons. Heart attacks are caused by blockages in the coronary artery preventing blood flow to the heart muscle. ...or ST-elevation MI undergoing primary percutaneous coronary intervention with balloon angioplasty and coronary stent implantation. Patients were randomized 2:1...Quitting smoking reduces risk of lung cancer mortality by 70 percent
...eliable evidence about the determinants of stroke, coronary heart disease, and other common causes of death in Asia-Pacific populations. It aims to produce region-, age- and sex-specific estimates of the cardiovascular disease risks associated with blood pressure, smoking, cholesterol, diabetes and other maj...Tiny clue reveals new path toward heart disease
...o a clinical tool for assessing a person's risk of coronary artery disease, so that physicians can try to prev...re and high cholesterol are known to contribute to coronary artery disease, little is known about genes that render an individual susceptible to developing the ...New research shows that flu is a trigger of heart attacks
... influenza epidemics are associated with a rise in coronary deaths. This calls for more intensive efforts to increase the vaccination rate in people at risk of coronary heart disease. This may be especially important in an influenza pandemic when we would expect to see...UW launches study testing adult stem cells for heart damage repair
...ubject's own stem cells can treat a form of severe coronary artery disease. The trial, just underway at UW Ho...hronic myocardial ischemia (CMI), a severe form of coronary artery disease. Myocardial ischemia, which affects hundreds of thousands of people, is a serious h...Link found between immune system and high plasma lipid levels
...rol and triglyceride levels, a key risk factor for coronary heart disease. "Besides showing a link between ...pid levels and chronic inflammation as manifest in coronary heart disease, ," said Fu, senior author on the paper. "It reveals a quite unexpected role of hepati...High-dose anticlotting drug cuts heart attack, death risk in half
...e anticlotting medication just before percutaneous coronary intervention (PCI) cuts the combined risk of heart...on the type of stent used to prop open the clogged coronary artery. To evaluate the effect of the clopidogrel loading dose, researchers from University of Tu...Study offers clues to 'Broken Heart Syndrome'
...terventional cardiologist finds no blockage in the coronary arteries. To date, the registry has enrolled 4...heart, then dissolves before being detected during coronary angiography. The most common symptom of broken heart syndrome was chest pain, in 70 percent of pa...Hearts of male and female rainbow trout are different
...the human heart, receives oxygenated blood via the coronary circulation. Conversely, the endocardium is supplied by only deoxygenated blood returning from the rest of the body. Not surprisingly, the authors expect there to be corresponding layer differences in energy production and function. Methodology ...Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism
...egalovirus antibodies, isolated from patients with coronary artery disease, are able to induce the activation ...virus-derived proteins purified from patients with coronary artery disease induce endothelial cells damage and support the hypothesis that virus infection plays...'Virtual autopsy' helps identify drowning as cause of death
...up of 12 men who were victims of sudden death from coronary artery disease. Following MDCT, routine autopsies were performed. MDCT images were evaluated for the presence of fluid and sediment in the paranasal sinuses and airways, fluid in the ear, frothy fluid in the airways, obscured "ground-glass" appear...Fat fish put obesity on the hook
...d to: hypertension, dyslipidemia, type 2 diabetes, coronary heart disease, stroke, gallbladder disease, osteoarthritis, sleep apnea and respiratory problems, and some types of cancer. ...University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts
...g continues to be the most commonly used graft for coronary artery bypass grafting even though a significant percentage of vein grafts eventually fail. Arterial grafts are the preferred conduits because they are less prone to becoming obstructed. However, they are in very limited supply, as many patients requ...Other ContentsmathematicalmathematicalmathematicalmathematicalmathematicalmaxmeiosismeiosismeiosismemorymemorymemorymemorymemorymemorymemorymemorymemoryinheritanceinheritanceinheritanceinheritanceinheritanceinheritancemetaphasemetaphasemetabolismmetabolismmetabolismmetabolismmetabolismmetabolismmetabolismmetabolismmetabolismOther TagsDataMateEndurIDENTIIDENTIIDENTIIDENTIIDENTIIDENTI
(Date:10/10/2008)...ersity and the Gladstone Institute of Cardiovascul...n improving the possibilities for the practical ap...echnology. , Previously, Dr. Yamanaka had shown ...ryonic stem celllike using a cancer-causing oncoge...the cells, and a virus to transfer the genes into ...
(Date:10/10/2008)...eus aculeatus , is one of the most thoroughly stud...arly useful model for understanding variation in p...aused by different ecological situations in the wi...netic to developmental and morphological, and fina...n far more complex than even imagined. , Studies...
(Date:10/10/2008).... , DNA, the molecule that acts as the carrier...ighly resistant against alteration by ultraviolet ...tostability presents some puzzling problems. A key...al bases that make up the DNA molecule. Researcher...t DNA strands differ in their light sensitivity de...
(Date:10/9/2008)...irstCall/ -- Aware, Inc. (Nasdaq:,AWRE), a leading...oftware,has scheduled a conference call to discus...arter of 2008 on Thursday, October 23, 2008, at 5:...Rick Moberg will host the,earnings conference call...be accessed on the,Investor Relations page of our ...
Breaking Biology News(10 mins):Yamanaka eliminates viral vector in stem cell reprogramming 2Fitness in a changing world 2Fitness in a changing world 3Can genetic information be controlled by light? 2Aware Announces Q3 2008 Earnings Conference Call 2Protein Research Marketing Insights 7872 1Protein Research Marketing Insights 7872 2Protein Research Marketing Insights 7872 3Established Safety Profile of Spiriva Confirmed by 30 Rigorously Controlled Clinical Trials and the Landmark Trial UPLIFT 3131 1Established Safety Profile of Spiriva Confirmed by 30 Rigorously Controlled Clinical Trials and the Landmark Trial UPLIFT 3131 2Established Safety Profile of Spiriva Confirmed by 30 Rigorously Controlled Clinical Trials and the Landmark Trial UPLIFT 3131 3Established Safety Profile of Spiriva Confirmed by 30 Rigorously Controlled Clinical Trials and the Landmark Trial UPLIFT 3131 4Established Safety Profile of Spiriva Confirmed by 30 Rigorously Controlled Clinical Trials and the Landmark Trial UPLIFT 3131 5Lack of large scale experiments slows progress of environmental restoration 5033 1Lack of large scale experiments slows progress of environmental restoration 5033 2Icahn Responds to Cornelius 7871 1Icahn Responds to Cornelius 7871 2Icahn Responds to Cornelius 7871 3(Date:10/10/2008)..., ANN ARBOR, Mich.---The University of Michigan...of Health to develop the world,s leading resource ...ing compounds that will ultimately take computer-a... will house the data needed to improve computer pr...tial new drugs, said Heather Carlson, associate pr...
(Date:10/10/2008)... NEW YORK, Oct. 10 /PRNewswire/ -- The Johns H...a novel multimedia educational program,"Optimizin...rs to Treatment,Selection," to present recent key ...cer treatment., In recent years, advancements in ...erapeutic and biologic treatment combinations that...
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