Cord in Biological News

Clinical trial shows quadriplegics can operate powered wheelchair with tongue drive system

... be operated by individuals with high-level spinal cord injuries, according to the results of a recently ... simple for individuals with high-level spinal cord injuries to use," said Maysam Ghovanloo, an ... tetraplegia, as a result of high-level spinal cord injuries (cervical vertebrae C3-C5), to perform ...

Children's Hospital Oakland scientists first to discover new source for harvesting stem cells

... more stem cells in placentas than in umbilical cord blood, and they can be safely extracted for ... likely that placental stem cells, like umbilical cord blood and bone marrow stem cells, can be used to ... a red blood cell. Using stem cells from umbilical cord blood, Children's Hospital Oakland physicians ...

Brain-computer interface, developed at Brown, begins new clinical trial

... goal of which is to help patients with spinal cord injury, stroke, muscular dystrophy, amyotrophic ... may help people with brain and spinal cord injuries and diseases," Donoghue said. "We are ... but also to assist people with ALS, spinal cord injury and brainstem stroke to control their ...

Identification of a key molecular pathway required for brain neural circuit formation

... made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. This new ... as an axonal attractant for brain and spinal cord neurons. "How exactly Shh elicited this effect ... It paves the way to new therapies to treat spinal cord injuries, neurodevelopmental disorders, and ...

Multiple route bone marrow stem cell injections show promise to treat spinal cord injury

... routes can be an effective treatment for spinal cord injury (SCI) that returns some quality of life ... is no cure or effective treatment for spinal cord injury, a disorder affecting millions globally. ... Following primary trauma to the adult spinal cord there is evidence of hemorrhage and blood flow is ...

Swamping bad cells with good in ALS animal models helps sustain breathing

... with healthy ones in targeted parts of the spinal cord preserves limb strength and breathing and can ... the added cells - parts of the cervical spinal cord that control the diaphragm muscles largely ... overall to specific sites in the cervical spinal cord of each model rat in early stages of disease. The ...

New technology enhances therapeutic potential of cord blood stem cells

... the efficiency and responsiveness of umbilical cord blood for bone marrow transplants and may improve ... at the 6th Annual International Umbilical cord Blood Transplantation Symposium, June 6-7 in Los ... essential step in stem cell transplantation. cord blood is increasingly being used by transplant ...

Promising new nanotechnology for spinal cord injury

... CHICAGO -- A spinal cord injury often leads to permanent paralysis and ... at the injury site and enables the severed spinal cord fibers to regenerate and grow. The gel is injected as a liquid into the spinal cord and self -assembles into a scaffold that supports ...

Umbilical cord blood cell therapy may reduce signs and symptoms of Alzheimer's disease

... Targeted immune suppression using human umbilical cord blood cells may improve the pathology associated ... a series of low-dose infusions of human umbilical cord blood cells into mice with Alzheimers-like ... observed in Alzheimers. Human umbilical cord blood cell therapy appeared to suppress ...

Umbilical cord blood cell therapy in an animal model of Alzheimer's disease

... targeted immune suppression using human umbilical cord blood cells may improve the pathology and ... a series of low-dose infusions of human umbilical cord blood cells into mice with Alzheimers-like ... pro-inflammatory molecules. Human umbilical cord blood cell therapy was associated with ...

Trainor Lab characterizes gene essential for prenatal development of nervous system

... and cell-fate determination in the spinal cord by coupling progression through the cycle of cell ... factor in regulating key aspects of spinal cord neurogenesis, said Angelo Iulianella, Ph.D., ... to extend these findings not only to spinal cord development, but also to the mammalian cortex, ...

Researchers take first steps towards spinal cord reconstruction following injury

... the regeneration of nerve cells following spinal cord injury, using the bodys own stem cells. This ... movements of stem cells following brain or spinal cord injury, says Dr. Philip Horner, co-lead ... events needed to repair the injured spinal cord and provides us with new targets for potential ...

Jefferson urologists studying regenerated neo-bladder to help spinal cord injury patients

... can improve bladder function for adult spinal cord injury patients. Jefferson is only one of six ... must be 18 to 65 years of age, have had a spinal cord injury for more than a year and diagnosed with a ... with bladder control problems due to spinal cord injury, the possibilities for expansion into ...

U of M begins nation's first clinical trial using T-reg cells from cord blood in leukemia treatment

... T-regs in this study are isolated from umbilical cord blood (blood collected from the placenta or ... the world that uses T-regs derived from umbilical cord blood. This trial is designed to find the ... suppressed patients undergoing a double umbilical cord blood transplant for leukemia, other blood ...

Researchers design first model motor nerve system that's insulated and organized like the human body

... are located in the body. In the central nervous system (CNS), the spinal cord and brain are surrounded by cerebrospinal fluid that contains only trace ... unmyelinated nerves to reveal how nerves malfunction as well as for spinal cord injury studies. "Being able to study these fully developed structures ...

CWRU receives $5 million from Ohio Third Frontier Commission

... its potential to treat a variety of neurodegenerative diseases and spinal cord injury. Pilot programs The pilot projects represent early stage, ... Targeting will apply its cell "painting" technology to direct umbilical cord blood stem cells to specific locations in the body to increase cell dosage ...

Jefferson researcher awarded Landenberger Foundation grant for ALS research

... and the spinal cord. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the ...

Therapeutic hypothermia is promising strategy to minimize tissue damage

... of the benefits of cooling strategies to protect the brain and spinal cord after traumatic injury has led to a wealth of cutting edge research, prime ... stroke and subarachnoid hemorrhage, traumatic brain (TBI) and spinal cord injury, and pediatric TBI and asphyxia. Mackensen et al. focus on ...

UCLA stem cells scientists make electrically active motor neurons from iPS cells

... signaling. Motor neurons receive signals from the brain and spinal cord and regulate muscle contraction. The study demonstrates the ... their causes. Motor neurons are lost in many conditions, including spinal cord injury, Amyotrophic Lateral Sclerosis and Spinal Muscular Atrophy. "A ...

Georgia Stem Cell Initiative meets on MCG campus Feb. 10

... Institute of Molecular Medicine and Science, Neuroscience Institute and cord Blood bank, "Research Utilization of the MCG cord Blood Bank." 10:15 a.m. - Dr. David C. Hess, chair of the MCG ...

Motor nerve targeting to limb muscles is controlled by ephrin proteins

... present in the developing limb control nerve targeting from the spinal cord to the muscles of the limb. This discovery, co-authored by scientists from ... Kania, "we study a simple system in which nerves extend from the spinal cord to the limb to connect to either flexor muscles (i.e. biceps arm muscle) ...

Response to immune protein determines pathology of multiple sclerosis

... to a protein produced by invading T cells dictates whether it's the spinal cord or cerebellum that comes under fire. The studyfrom researchers at the ... . In most MS patients, the disease primarily affects the spinal cord and the white matter of the brain. But a small percentage of patients ...

NIH EUREKA grant awarded to University of Miami scientist

... (NIH), to develop a technique that can lead to a new treatment for spinal cord injury. Dr. Chiba, a professor at the University of Miami's Department of ... said Chiba. "A Holy Grail of regenerative neuromedicine is spinal cord repair," he said. "It would be rash to predict that our project will solve ...

The pepperoni pizza hypothesis

... together like telephone wires and plug into the same region of the spinal cord near the tailbone. People with interstitial cystitis have bladder ... from a visceral organ, the pain message is delivered to the spinal cord and bounces out to the corresponding skin surface, called the dermatome. ...

$3.2M for Rutgers to apply biology, engineering, physical sciences toward stem cells

... the grant will strengthen our efforts to find cures for brain and spinal cord injuries and disorders," said Dr. Wise Young, Richard H. Shindell Professor of Neuroscience at Rutgers. Young, a world leader in spinal cord injury and treatment and an outspoken advocate for stem cell research, is ...

Children's national co-leads nationwide study of landmark sickle cell treatment

... for a new national clinical trial of unrelated donor marrow and umbilical cord blood transplants for severe sickle cell disease . Children's National ... acute chest syndrome, or frequent pain crises. For all marrow and cord blood transplants, patients must undergo intense chemotherapy to prevent ...

American Chemical Society's Weekly PressPac -- Aug. 6, 2008

... beef that has been contaminated with tissue from a cow's brain or spinal cord during slaughter an advance in protecting against possible spread of the ... in bovine carcasses and meat cuts. "Small quantities of bovine spinal cord were reliably detected in the presence of raw bovine skeletal muscle, fat ...

Treating chronic pain, migraine & muscle spasticity through inhibition of neurotransmitter glutamate

... Tuchman will present information about glutamate receptors in the spinal cord as a target for muscle spasticity. He has served as Vice Chairman of the ... pain as well as muscle spasticity and rigidity secondary to spinal cord trauma, stroke and multiple sclerosis. ...

Brown to host conference on advances in neurotechnology

... disciplines: cochlear (ear) implants and retinal (eye) prosthetics; spinal cord injuries; deep brain stimulation; and paralyzed rehabilitation. The ... of the Health Sciences. Ling's research focuses on brain and spinal cord injuries, particularly those relevant to the military. His address is ...

Bacterial infections in premature babies more common than previously realized

... gestational age at delivery, the higher the rate of a positive umbilical cord blood culture. The data, derived from the Alabama Preterm Birth Study, ... on a subset of 351 women/infant pairs in the population who had umbilical cord blood cultures for U. urealyticum and M. hominis. Writing in the ...

UC Irvine scientists find new way to sort stem cells

... therapies for people with conditions ranging from brain and spinal cord damage to Alzheimers and Parkinsons diseases. The method uses ... were destined to become neurons, which are cells in the brain and spinal cord that process and transmit information. Neurons that die as a result of ...

Salk scientists identify key nerve navigation pathway

... that guides motor neurons the nascent cells that extend from the spinal cord and must find their way down the length of limbs such as arms, wings and ... In the mutants, growing neurons can be seen leaving the spinal cord normally but then appear to lose direction. The elongating cells develop ...

Rutgers scientist's research reveals critical knowledge about the nervous system

... electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the nervous system. With $697,065 in grants from the New Jersey Commission on Spinal cord Injury and the New Jersey Commission on Brain Injury Research, Haesun Kim ...

Low vitamin D during pregnancy linked to pre-eclampsia

... pregnancy and again just before delivery. Samples of newborn umbilical cord blood also were tested for 25 hydroxyvitamin D, an indicator of vitamin D ... D from the mother, low vitamin levels also were observed in the umbilical cord blood of newborns from mothers with preeclampsia. A vitamin closely ...

Stem cell research: From molecular physiology to therapeutic applications

... or damaged cells and tissues in patients. Recent studies have shown that pluripotent stem cells derived from adult bone marrow, the umbilical cord and the placenta could also be induced to differentiate into a variety of different tissues. In this issue, we have invited several scientists in ...

Wood stoves -- a viable home heat source?

... the mean annual gas cost by 60%; from $2260 to $880. The annual cost of the wood fuel for the woodstove amounted to $1330 for 5 full cords (a cord is 8 feet long by 4 feet high by 4 feet wide - 128ft3 ). This was a yearly savings of $50 at market fossil fuel prices of 2005-2007 without taking ...

NYC science symposium marks Gruber Prize program 10th anniversary

... Institute and recipient of the Max Planck Research Prize, whose work may eventually make possible the replacement or enhancement of brain and spinal cord tissue lost or damaged due to neurodegenerative disease or trauma, will speak on "Brain Plasticity and Diversity." Dr. Solomon Snyder, professor ...

Partnership to accelerate Trudeau Institute discoveries to patient care

... Antigen test ("PSA test"), HIV-1 co-receptor usage test, photodynamic cancer therapy, assistive communication devices for persons with spinal cord injuries, and several pharmaceuticals. "As a basic research institution, discoveries made at the Trudeau Institute often lead to vaccines and ...

BIO 2009 -- R&D session: New stem cell research unlocks unknown therapies

... cell research, currently one of the most exciting areas in science, and how it unravels potential new therapies for Parkinson's, Alzheimer's, spinal cord injury, stroke, heart diseases and other devastating diseases. He is also the scientific founder of NeuroNova, a biopharmaceutical company, ...

Just in time for spring: Scientists find the cellular on and off switch for allergies and asthma

... these and other related diseases." Ryan and colleagues made this discovery in mouse experiments that examined cells from bone marrow and umbilical cord blood that ultimately help create a type of immune cell (mast cells). Too many mast cells lead to an over-aggressive immune response, which causes ...