Gene therapy reversed heart damage in heart failure
... with ARKct was sufficient to reverse heart failure even without concomitant metoprolol. The rats that received GFP or saline alone experienced more ... of the study. This deterioration was prevented, but not reversed, with the concomitant metoprolol. "Our data show that beta blockers and the ARKct ...Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia
... activation, led us to conclude that the elevated frequency per se and concomitant Ca2+-overload precede and induce mitochondrial dysfunction and oxidative ... cellular effects that are solely due to the AF excluding the effects of concomitant cardiac diseases. Dr. Steven R. Goodman, Editor-in-Chief of Experimental ...Early initiation of Arctic sea-ice formation
... the atmosphere and increased the amount of solar radiation reflected back out into space. "A stable sea-ice regime also suggests the possibility of concomitant glacial ice," say the researchers, and indeed they find some evidence for the presence of small isolated glaciers at the time. Furthermore, their ...Fire is important part of global climate change, report scientists
... report. "The tragic fires in Victoria, Australia, emphasize the ubiquity of recent large wildfires and potentially changing fire regimes that are concomitant with anthropogenic climate change," said first author David Bowman, professor at the University of Tasmania. "Our review is both timely and of great ...Protein structure determined in living cells
... Gntert. "Unfortunately, the cells survive for only a 5-6 hours without supply of oxygen and nutrients. Gntert and his colleagues compensated for the concomitant drastic reduction of the measurement time by computational reconstruction of the complete spectrum. Then, they calculated a detailed ...Organic plant waste proves effective weed control for citrus trees
... effectively for controlling weeds in citrus groves. Their effectiveness in controlling weeds may increase their use in agriculture systems with a concomitant decrease in the need for synthetic herbicides. Further studies are needed to evaluate their side effects on beneficial organisms, diseases, and ...New cardiology research presented at CHEST 2008
... therapy for patients with pulmonary arterial hypertension (PAH). Italian researchers randomized 405 patients with PAH, of whom 53 percent were taking concomitant bosentan, to two study arms. The groups received either tadalafil or placebo orally once daily as monotherapy or as add-on therapy to bosentan. ...Cow power could generate electricity for millions
... attempt to outline a procedure for quantifying the national amount of renewable energy that herds of cattle and other livestock can generate and the concomitant GHG emission reductions. Livestock manure, left to decompose naturally, emits two particularly potent GHGs nitrous oxide and methane. According ...Influenza vaccine causes weaker immune response for children of rural Gabon than in semi-urban areas
... than in their semi-urban counterparts, likely because of co-infection with parasites and/or poor nutrition. Closer attention to nutrition and concomitant infections may profoundly affect responses to pandemic influenza and influenza vaccines in developing countries. With the current attention to ...Protein may hold key to decreasing organ dysfunction rates in heart transplants
... involvement in the systemic response to IR. "The major goal of our research activities is therefore to understand the exact mechanisms of this injury concomitant to organ transplantation," notes Aigner, stressing the value of this research to the development of new treatment options in organ transplantation. ...Monoclonal antibody reduces exacerbations in asthmatics
... ineffective in patients with chronic obstructive pulmonary disease (COPD)," said Dr. Hansel. "Preliminary reports of efficacy in asthma patients with concomitant rheumatoid arthritis have been encouraging. Small prospective studies of a soluble receptor directed against TNFá in severe refractory asthma have ...Altered perception of reward in human cocaine addiction
... attribute salience, or value, to their drug of choice at the expense of other potentially but no-longer-rewarding stimuli -- with a concomitant decrease in the ability to inhibit maladaptive drug use. In the experiments, the scientists subjected cocaine-addicted and non-drug-addicted ...Dissecting the machinery of nicotine's reward
... involved in such behaviors as curiosity or interest in novelty, wrote the researchers. The researchers concluded that their "data suggest that a concomitant activation of [ß2 and a7 receptor subunits] may be a necessary requirement for the full expression of the sequence of events leading to nicotine ...Just the expectation of a mirthful laughter experience boosts endorphins 27 percent, HGH 87 percent
... changes in neuroendocrine response prior to the onset of the event itself," Berk said. "From our prior studies, this modulation appears to be concomitant with mood state changes, and taken together, these would appear to carry important, positive implications for wellness, disease-prevention and most ...Parents need to be educated about HPV vaccinations for daughters
... despite the vaccination. Falling death rates have also been due to improved forms of treatment for advanced disease, principally in the form of concomitant chemotherapy and radiotherapy." Professor Kitchener concluded: "HPV vaccines provide hope for major international programmes of primary ....Combination therapy improves AIDS-related lymphoma outcome
... median survival was only 7.2 months. Sixty-nine percent reported moderate toxicity. "The present study showed that our risk-adapted strategy for concomitant administration of HAART with CHOP is effective and safe," the authors concluded. ...Scientists fetch useful information from dog genome publications
... a new book entitled The Dog and Its Genome and a series of primary research articles in the journal Genome Research . These publications, concomitant with the publication by Nature of a high-quality draft sequence of the dog genome, are expected to provide both researchers and the public with ...Scientists decipher genome of fungus that can cause life-threatening infections
... and Microbiology at the Duke University Medical Center and an investigator at the Howard Hughes Medical Institute. "In Africa, where both HIV and concomitant cryptococcal infection are common, survival without therapy is as short as 7 to 10 days following diagnosis." The major virulence factor of C. ...