Clinical in Biological News

Advances in lung cancer research announced at conference

... and Director of Thoracic Oncology at TGen clinical Research Services at Scottsdale Healthcare, made ... Center at Scottsdale Healthcare's Scottsdale clinical Research Institute; Scottsdale Medical Imaging ... Scottsdale Healthcare of results from two Phase I clinical trials for a drug called TH-302. The ...

First human gets new antibody aimed at hepatitis C virus

... (UMMS) today announced the beginning of a Phase 1 clinical trial, testing the safety and activity of a human ... are pleased that this program has now entered the clinical trial phase," said Donna Ambrosino, MD, executive ... markedly reduced survival rates. To close that clinical gap, the new antibody developed at MassBiologics ...

Stem cell research: From molecular physiology to therapeutic applications

... group has taken stem cell therapy into phase II clinical trials in China, and is the leading runner in ... complex mechanism of MSCs' immune modulation and clinical studies, and discusses future directions for utilizing MSCs for clinical treatments[2]. Professor Hongkui Deng from ...

Test helps in fight against lung infections and for treating other life-threatening infections

... among the most life threatening lung infections. clinical research of bioFILM PA™ shows how the test ... kill than free-floating bacteria. While the clinical research focused on patients with CF, the bioFILM ... Adult Cystic Fibrosis Clinic conducted the clinical research from 2007 to 2009. ...

Genetic tests advertised directly to the consumer

... to a position paper from the American College of clinical Pharmacology (ACCP) to be published in the August 2009 issue of the Journal of clinical Pharmacology . The journal is published on behalf ... A Position Statement of the American College of clinical Pharmacology," prescription medications have been ...

$20 million NIH grant to transform clinical research at UIC

... University of Illinois at Chicago's Center for clinical and Translational Science. The grant is the ... and further study to create beneficial clinical practices, and the NIH is funding us to ... process," Tanner said. The NIH launched the clinical Translational Science Award program in 2006 to ...

$29.4 million grant establishes CTSI at NYU in partnership with Health and Hospitals Corporation

... of Medicine received a $29.4 million, five-year clinical and Translational Science Award from the National ... of Health (NIH) to establish a University-wide clinical & Translational Science Institute (CTSI) in ... HHC will become part of a network of 46 existing clinical and Translational Science centers based at ...

Results from trials of DHA in Alzheimer's disease and age-related cognitive decline

... a double blind, randomized, placebo-controlled clinical trial comparing DHA and placebo in 402 people ... scale-cognitive (ADAS-cog) and rate of change on clinical Dementia Scale-sum of the boxes (CDR-SOB). These ... by Karin Yurko-Mauro, PhD, Associate Director of clinical Research at Martek, conducted a randomized, ...

Mount Sinai's Dr. Benjamin tenOever to be honored by White House

... is internationally acclaimed for excellence in clinical care. Last year, nearly 50,000 people were ... recognized as a leader in groundbreaking clinical and basic science research, as well as having an ... With a faculty of more than 3,400 in 38 clinical and basic science departments and centers, Mount ...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

... maximising the efficacy of the drug within the clinical target and minimising adverse events. For ... to the progressive integration of basic research, clinical neuroscience and medical practice, which can ... messages that can easily be translated into clinical practice by medical professionals. The ...

New lab test offers better prediction of HIV microbicide safety

... Several microbicide gels have been assessed in clinical trials after passing laboratory and animal safety ... are predictive of safety before proceeding to clinical trials that typically cost millions of dollars, ... safe in all of the other bioassays and in early clinical trials. These findings may explain the ...

LSUHSC research helps link schizophrenia to specific DNA region

... Buccola, APRN, PMH CNS-BC, Assistant Professor of clinical Nursing at LSU Health Sciences Center New Orleans, who also coordinated the ten clinical sites. The work, Common variants on chromosome ... which included LSUHSC Assistant Professor of clinical Psychiatry, Margaret Baier, MD, and Erich Conrad, ...

Genetic factors implicated in survival gap for breast, ovarian or prostate cancer

... analysis of almost 20,000 patient records from 35 clinical trials, points to biological or genetic factors ... The study analyzed patient records from clinical trials going back as far as 1974 conducted by ... data published last month in the Journal of clinical Oncology (JCO), which found that disparities in ...

First cGMP feeder-independent pluripotent stem cell banks released for distribution

... The WiCell Research Institute and the Waisman clinical Biomanufacturing Facility (WCBF) announced today ... advance their programs from research through clinical application. In the future, WiCell and the WCBF ... and produced under conditions suitable for human clinical trials," says Thomson, director of regenerative ...

Journal of Vascular and Interventional Radiology: New patient radiation safety guidelines

... dose management) and previously published clinical practice guidelines developed since 2003 through ... guidelines collection to improve the quality of clinical care and published research relevant to the ... societal position on such topics as the role of clinical associates in interventional radiology. There are ...

Clinical trial shows quadriplegics can operate powered wheelchair with tongue drive system

... according to the results of a recently completed clinical trial. "This clinical trial has validated that the Tongue Drive system ... reported the results of the first five clinical trial subjects to use the Tongue Drive system. ...

Single thawed embryo transfer after PGD does not affect pregnancy rates

... no significant difference in the implantation and clinical pregnancy rates (35% versus 29% and 34% versus ... said: "This research suggests that responsible clinical decisions do not have to come at the expense of ... the chances of success for your patients by good clinical judgment and using the appropriate techniques. ...

New biomarker method could increase the number of diagnostic tests for cancer

... in its earliest stages. The results of the clinical Proteomic Technology Assessment for Cancer ... hurdles in validating protein biomarkers for clinical use. Thousands of cancer biomarkers are ... day, but only a handful ever makes it through clinical validation. This is a critical roadblock because ...

CWRU receives $5 million from Ohio Third Frontier Commission

... cell research from the lab to patients through clinical trials, using our strong background in ... research efforts will result in efficient clinical applications and commercialization of stem cells ... are making Ohio a leader in the development and clinical use of cellular therapies," said Baiju R. Shah, ...

Study shows Chronix technology using serum DNA can identify early presence of disease

... specific signature sequences in serum DNA before clinical symptoms appeared in animals experimentally ... the development of laboratory tests for routine clinical use," said Howard Urnovitz, Ph.D., CEO of ... of BSE in all of the infected animals well before clinical symptoms appeared." These new findings follow ...

A urine test for appendicitis?

... PhD, director of the Proteomics Center, and clinical fellow Alex Kentsis, MD, PhD, decided to take a ... for the markers were not told the patients' clinical status, to ensure unbiased assessment of the test ... by immunoblotting, suggesting that a rapid clinical test, such as a urine dipstick, could be ...

Green tea may affect prostate cancer progression

... few trials conducted to date have evaluated the clinical efficacy of green tea consumption and few studies ... conducted this open-label, single-arm, phase II clinical trial to determine the effects of short-term ... normal. Results of a recent year-long clinical trial conduced by researchers in Italy ...

Major breakthrough in early detection and prevention of AMD

... us closer than we have ever been to developing a clinical diagnostic tool to discover and treat the disease ... to detect CNV could potentially be useful as a clinical treatment to prevent macular degeneration. The ... percent with VEGF-based treatments currently in clinical use. Ambati says Phase ...

German Research Minister Schavan: 'Rapid knowledge transfer can safe lives'

... are swiftly transferred from the laboratory into clinical practice. Framework conditions for this research ... access to patients, samples and an effective clinical environment. In return, the sites will be given ... as swiftly and directly as possible into the clinical care of cancer patients," Professor Otmar D. ...

Brain-computer interface, developed at Brown, begins new clinical trial

... devices, is about to begin a second, larger clinical trial. The system is based on neuroscience, ... at Brown University. The BrainGate2 pilot clinical trial is taking place at Massachusetts General ... to control assistive devices. The new clinical trial is part of a larger BrainGate research ...

Colon cancer screening technique shows continued promise in new study

... Recent clinical trials show that a new colon cancer screening ... published in the journal Cancer Research . clinical trials have been conducted in collaboration with ... HealthSystem. The study is a step toward clinical application of the technology, since it used ...

Amarna Therapeutics B.V. and TNO announce SVac research and development partnership

... TNO enables us to initiate the first time in man clinical trials with one of our lead therapeutics in ... to serve markets with enormous potential due to clinical unmet needs. About SVac Our SVac viral ... Control (QC) assays and its use for manufacturing clinical trial material has been validated. The whole ...

American Society for Microbiology honors Melissa B. Miller

... to Melissa B. Miller, Ph.D., D(ABMM), director, clinical Molecular Microbiology Laboratory, assistant ... and Laboratory Medicine, and associate director, clinical Microbiology-Immunology Laboratory at the ... recognizes outstanding laboratory research in clinical microbiology or antimicrobial agents. Dr. ...

American Society for Microbiology honors Lynne S. Garcia

... bioMrieux Sonnenwirth Award for Leadership in clinical Microbiology is being presented to Lynne S. ... microbiologist for the promotion of innovation in clinical laboratory science, dedication to ASM, and the advancement of clinical microbiology as a profession. Recognized as ...

American Society for Microbiology honors James W. Snyder

... contributions to the professional recognition of clinical microbiologists and/or immunologists. Dr. ... form the basis for the training of frontline clinical microbiologists to be prepared for detection and ... microbiological testing. Dr. Snyder represented clinical microbiologists and provided essential input to ...

Faculty of Translational Medicine boosts support for biomedical researchers

... programmes, statistical advice and consultancy on clinical trial design receive support for the use of cutting-edge technologies run studies in dedicated clinical trials facilities keep abreast of the latest ... and improved diagnosis and prognosis. The new clinical research facilities will enable us to care for ...

Scientists discover new genetic immune disorder in children

... us understand other common diseases that share clinical features, such as psoriasis, as well as other ... unrecognized autoinflammatory syndrome. The clinical characteristics were distinct from other diseases ... team of dedicated investigators," said NIAMS clinical Director and coauthor Daniel L. Kastner, M.D., ....

First comprehensive guidelines for managing medullary thyroid carcinoma published in Thyroid journal

... has published the first comprehensive set of clinical guidelines for the treatment of all medullary ... become a benchmark for patient management and clinical research, as they illuminate the diagnostic and ... recommendations that cover a range of clinical topics, including diagnosis and therapy for early ...

One size does not fit all

... on other cellular processes, were propelled into clinical trials based on studies in an animal model of MS indicating a reduction in clinical disease severity," says Dr. Veronique Miron, ... the direct impact of simvastatin, a statin in clinical trials, on the integrity of myelin in the brain ...

Comprehensive cardiogenetic testing for families of sudden unexplained death victims can save lives

... deceased person or in those relatives who showed clinical abnormalities. The researchers found inherited ... be referred to cardiogenetics departments, where clinical geneticists, cardiologists and psychosocial ... specialise in inherited heart diseases and their clinical and psychosocial implications, and can provide a ...

Tips from the American Journal of Pathology

... was not expressed in stroma of patients with poor clinical outcome. In addition, tumor onset in mice was ... an important and potentially powerful source of clinical information to predict patient outcome, and ... specifically that stromal Cav-1 may be a valuable clinical marker. Determining whether stromal Cav-1 ...

Genetic testing for breast or ovarian cancer risk may be greatly underutilized

... of bringing genetic information into real-world clinical practice. "Testing for BRCA1 and 2 mutations ... genetic test is not being incorporated into clinical practice when appropriate, we are a long way from ... of the genes. Several organizations have issued clinical guidelines designating who should be screened for ...

NIH announces new program to develop therapeutics for rare and neglected diseases

... preventing potential therapies from entering into clinical trials for rare or neglected disorders. While we ... are successful can a potential treatment move to clinical trials in patients. Unfortunately, the success ... of projects fail there, never making it to clinical trials. And the costs are high: it takes 2-4 ...

SNM's clinical trials network gains added support from industry leader

... Reston, Va.The SNM clinical Trials Network, an initiative designed to address ... of imaging biomarkers into multi-center clinical trials, recently added Genentech, Inc. as a ... molecular imaging professionals, inaugurated the clinical Trials Network in late 2008 to facilitate more ...

Interventional radiology: From sidelines to mainstream for patients

... College of Radiology resolution in support of clinical patient management by vascular and interventional ... unique contribution of supporting innumerable clinical services while providing direct care," said SIR ... Stainken. ACR endorsed interventional radiology's clinical patient-centered nature 10 years ago, recognizing ...