Cholera in Biological News

The tiny difference in the genes of bacteria

... is more commonly known as the causative agent of cholera that spread in Europe until the 20th century. ... those strains cause severe diarrhoea known as cholera that produce a certain bacterial toxin which ... may also gain importance in Europe. As in the cholera bacterium, various Vibrio parahaemolyticus ...

The tiny difference in the genes of bacteria

... is more commonly known as the causative agent of cholera that spread in Europe until the 20th century. ... those strains cause severe diarrhoea known as cholera that produce a certain bacterial toxin which ... may also gain importance in Europe. As in the cholera bacterium, various Vibrio parahaemolyticus ...

Polarized light guides cholera-carrying midges that contaminate water supplies

... cholera is a major killer and since the first pandemic in ... start in life to the midges' larvae, and their cholera bacteria hitchhikers. The team are also keen ... could help control midge numbers and minimise cholera transmission. They suggest that by reducing the ...

Hidden infections crucial to understanding, controlling disease outbreaks

... explain puzzling patterns seen in 50 years of cholera death records from 26 districts in Bengal, ... "native habitat." "In that region, we see two cholera seasons per year, with peaks in spring and fall," ... over periods of three to five years, with many cholera cases reported during some periods and few during ...

Scientists use remote satellite imaging to predict outbreaks of infectious disease

... of other important infectious diseases. cholera is a serious, ancient water-borne infectious ... which lives on zooplankton, a type of plankton. cholera outbreaks have been linked with environmental ... collected now can be used to predict outbreaks of cholera before they occur. ...

Climate and cholera

... cholera outbreaks may soon be predicted using satellite ... Edinburgh International Conference Centre. The cholera Vibrio lives in zooplankton and can be found in ... sea surface temperature, sea surface height and cholera epidemics, says Professor Colwell, from the ...

Seventy-three scientists elected to the American Academy of Microbiology

... Yamagata, Japan Anne Moscona, Weill Medical College of Cornell University, New York City Gopinath Balakrish Nair, National Institute of cholera and Enteric Diseases, Kolkata, India Ann C. Palmenberg, University of Wisconsin, Madison Yvonne Paterson, University of Pennsylvania School of ...

Scripps research scientists identify blood component that turns bacteria virulent

... This finding also is significant because other pathogenic bacteria such as Streptococcus pyogenes, Escherichia coli, Borrelia burgdorferi, and Vibrio cholera have bicarbonate transport pathways similar to B. anthracis and thus are likely to have similar virulence triggering mechanisms. Gram-positive ...

New antibiotic candidates from Braunschweig

... results in the distinguished journal "Cell". Antibiotics are an essential tool of medicine. We owe the antibiotics that diseases such as plague, cholera or tuberculosis are a thing of the past, at least in the industrialised world. However, more and more bacteria are becoming resistant to ...

Microbial stowaways: Are ships spreading disease?

... said Professor Dobbs. The majority of these microbes are harmless, but some are a potential risk to public health. Vibrio cholerae, which causes cholera in humans, can be carried in ballast tanks, said Professor Dobbs. There have been no known outbreaks of disease associated with ballasting ...

Rainfall and river networks prove accurate predictors of fish biodiversity

... Rinaldo also collaborated on a paper that recently appeared in an American Geophysical Union publication on how river networks affect the spread of cholera epidemics. Seeds and bacteria are different from fish -- obviously they cant swim upstream, said Rodrguez-Iturbe. But like fish, their ...

Small molecule inhibitor of cholera discovered

... states and Guatemala have raised the risks of cholera outbreaks, researchers at Harvard Medical School ... identified a new type of antibiotic against the cholera bacteria. While traditional antibiotics kill ... showed that the most promising compound prevented cholera bacteria from setting up an infection when ...

Professors to develop hand-held pathogen testing device

... of a thumbnail. Today, testing air, water or food for pathogens like cholera and dysentery must be done one pathogen at a time. Testing for each ... but are not dangerous to humans by themselves. But the gene producing the cholera toxin is harmful. These genes serve as good markers for detection. ...

Scientists design potent anthrax toxin inhibitor

... also because this technique could be used to design better therapies for cholera and other diseases," says NIH Director Elias A. Zerhouni, M.D. The ... on a liposome, the researchers also created a polyvalent inhibitor of cholera toxin that functioned well in test-tube experiments. In the next phase ...

Say what? Bacterial conversation stoppers

... the cholera-causing bacteria that mixes with E. coli in human guts. When cholera bacteria sense a quorum, they turn off their toxins and excrete an enzyme ... Here, E. coli squelched much of the quorum-sensing response of the cholera bacteria, although the effect was not as dramatic as with the marine ...

Bacteria have their own immune system protecting against outside DNA

... in genetic information from diverse sources that makes them more virulent. "By harnessing foreign DNA, bacteria that cause typhoid, dysentery, cholera and plague have evolved from harmless organisms into feared pathogens," explained Dr. William Navarre, a senior fellow at the UW and primary author ...

U-M researchers take new approach to defeating Gram-negative bugs

... issue of the American Chemical Society's journal ACS Chemical Biology. Some of the better-known Gram negatives are salmonella, gonorrhea, cholera and meningicoccal meningitis, along with the bacteria that caused the black plague. Woodard and his collaborators worked on E. coli in part ...

Anthrax inhibitor counteracts toxin, may lead to new therapeutics

... toxins, including influenza and HIV," says Kane. The researchers tested their pattern-matching strategy by designing a polyvalent inhibitor for cholera toxin, demonstrating that this approach also could be used successfully to enhance the potency of polyvalent inhibitors directed to this target and, ...

Effective, safe anthrax vaccine can be grown in tobacco plants

... for several diseases. Daniell's work holds promise for treating other diseases, including diabetes and hepatitis, and improving vaccines for plague, cholera and other bioterrorism agents. Daniell is developing a new technology that would enable vaccines to be administered orally and allow effective and ...

Plant wounds trigger bacteria

... or animals, and respond by initiating an attack on these host organisms," Winans said. "For example, others have shown that the bacteria that cause cholera express protein toxins only when they detect bile salts in the host's intestine. It will be interesting to see whether those bacteria also increase ...

Active Vaccine Prevents Mice From Developing Prion Disease

... prions were attached to a genetically modified strain of Salmonella. This bacterium is also used in several animal vaccines and in human vaccines for cholera and typhoid fever. Among mice vaccinated prior to prion exposure, approximately 30% remained alive and symptom-free for 500 days, according to the ...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

... in the United States. But then came the antibiotic revolution. Antibiotic "wonder drugs" toppled tuberculosis (TB) and typhoid fever, controlled cholera and gonorrhea, reduced staphylococcal dysentery, and lowered the incidence of many other pandemic bacterial infections. These antibiotics are ...