cervical

Live Recombinant Adenovirus Vaccine Technique Explored

... the developing world. HPV causes 500,000 cases of cervical cancer each year worldwide. Recombinant HPV vaccines currently in clinical trials may not be ideal in poorer countries because they are expensive and require multiple immunizations. The Hopkins researchers developed their vaccine prototype using can...

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

...ma, and, to a lesser extent, anal cancer, invasive cervical cancer, and Hodgkin lymphoma. However, less well u...n increased risk of anal cancer, Hodgkin lymphoma, cervical cancer, liver cancer, cancer of the lip, mouth, and pharynx, and non-melanoma skin cancer. People wh...

Harmful chemicals may reprogram gene response to estrogen

...rm deliveries, infertility, and a rare vaginal and cervical cancer called clear-cell adenocarcinoma. Other res...xposure can lead to the development of vaginal and cervical cancers, the fact that most DES-exposed women did not develop the cancers suggests that genetic pred...

Survey reveals women and doctors aren't talking about HPV

...percent said their doctor has talked to them about cervical cancer and its cause - the human papillomavirus (H...are talking about the relationship between HPV and cervical cancer despite the fact that advanced screening is available, which can detect the virus early and h...

U of T researchers map role of Epstein-Barr virus in cancer

... cancer, like the human papillomavirus that causes cervical cancer for example, have been shown to work through this p53 protein, but up until now, no one's ever found any regulation of p53 that's associated with the Epstein-Barr virus. That was surprising because all other viruses that stimulate cell prolife...

Study: Harmless virus kills some cancers

...to develop human papillomavirus- (HPV-) associated cervical cancer. In general, AAV2 requires association with...uman papillomavirus (HPV). HPV is known to lead to cervical cancer. A second way AAV2 suppresses cancer is linked to its ability to slow cell-cycle progression ...

Mass production of human papillomavirus could lead to gains against cervical cancer

...loiting the vulnerabilities of a virus that causes cervical cancer, thanks to a newly developed technique that...pes of HPV are responsible for nearly all cases of cervical cancer, and other types contribute to about a quarter of head and neck cancers and some skin cancers...

Energy management in cells may hold key to cancer defense

...something besides LKB1." "We decided to work with cervical and lung cancer cells because LKB1 is absent from the cellular pathway," said Rebecca Hurley, lead author of the study and a graduate student in the Molecular and Cellular Biology Program at Dartmouth. Working closely with scientists at St. Vincen...

Gradient guides nerve growth down spinal cord

...ring the first week after birth they grow down the cervical and thoracic spinal cord until they reach their proper position, usually after seven to ten days. From previous studies, Zou and colleagues knew that a gradient of various Wnt proteins, including Wnt4, formed along the spinal cord around the time of...

Breast tumors in mice eradicated using cancer vaccine

...al trial targeting a tumor antigen associated with cervical cancer by Advaxis Inc., a cancer vaccine biotech company that has licensed Penn patents on the use of Listeria monocytogenes as a vaccine vector. Paterson is the scientific founder of Advaxis and Chair of the Scientific Advisory Board. The successful...

Surgical Robot 'Scrubs In' At UNC, May Be More Precise Than Conventional Surgery

...al surgery; for hysterectomies for endometrial and cervical cancers; and for pediatric gallbladder removal and stomach surgery to prevent gastric reflux. The robotic system gained federal government approval for gynecological use in April. "We've found the robotic operation to be more precise than conventio...

Screen all at risk for HIV, plus pregnant women

...al surgery; for hysterectomies for endometrial and cervical cancers; and for pediatric gallbladder removal and stomach surgery to prevent gastric reflux. The robotic system gained federal government approval for gynecological use in April. "We've found the robotic operation to be more precise than conventio...

FDA: 'Highly Unlikely' Green Tea Lowers Cancer Risk

...al surgery; for hysterectomies for endometrial and cervical cancers; and for pediatric gallbladder removal and stomach surgery to prevent gastric reflux. The robotic system gained federal government approval for gynecological use in April. "We've found the robotic operation to be more precise than conventio...

Updated data on novel HPV vaccine confirms efficacy in large population

...on a promising new vaccine against a pre-cancerous cervical virus shows superior efficacy in preventing cervical pre-cancers and non-invasive cervical cancer, according to a study presented today during the Americ...

Researcher uncovers details of how cancer spreads

...ncluding the herpes virus and its association with cervical cancer. "Critics of this work will ask why v-Src has not been found in human cancer," said Guan. "But there are many examples of studies and ideas that come out of work like this that stimulate related research with clinical impacts. "We looked at ...

Building a better mouse model of lung cancer: FHIT counts

... head and neck, esophageal, colorectal, breast and cervical cancers as well. Because the loss of FHIT occurs so early in lung cancer, mice that are missing that gene may be a good model in which to test new ways to treat or prevent the disease, says Huebner. "There are some other useful mouse models out ther...

Cyberkinetics, Case to develop system to help restore extremity function

...o individuals with extensive paralysis due to high cervical spinal cord injury (SCI). The joint project will c...ims to test the ability of an individual with high cervical SCI to control computers and other external devices with signals obtained from the motor cortex. Cyb...

Texas scientists discover how a hepatitis C protein promotes liver cancer

...lloma virus (HPV), the cause of genital warts, and cervical cancer, according to Dr. Stanley M. Lemon, the senior author of a paper on the discovery that will be published this week in the online early edition of the Proceedings of the National Academy of Sciences. "What we've found is that one of the hepat...

Parents need to be educated about HPV vaccinations for daughters

...ually transmitted virus that is the major cause of cervical cancer, the 4th International Conference on Teenag...women and men, particularly parents, about HPV and cervical cancer. Professor Kitchener, of the Academic Unit of Obstetrics and Gynaecology at the University o...

Cellular scale drug delivery from the inside out

... up to a liquid-filled glass vial containing human cervical cancer cells grown in vitro that contain nanospheres capped with iron-oxide particles. The cells slowly migrate and cluster to the side of the vial next to the magnet. "By using a powerful magnet, we can first concentrate the nanospheres at a parti...

Basic research leads to a novel cancer therapy

...h advanced forms of bladder cancer, breast cancer, cervical cancer, colon cancer, esophageal cancer, head and neck tumours, liver cancer, lung cancer, melanoma, ovarian cancer, pancreatic cancer, prostate cancer, and testicular cancer. The studies are in various stages of clinical trials (phases I through III...

HPV subtype associated with squamous cell skin cancers

...n associated with other epithelial cancers such as cervical cancer. Genus beta HPVs, which includes HPV types 5 and 8, have been detected in skin tumors, and previous studies suggest they may play a role in the development of these cancers. Margaret R. Karagas, Ph.D., of Dartmouth Medical School and Norris ...

Teens unaware of sexually transmitted diseases until they catch one, Carnegie Mellon study finds

...nital warts can render a woman more susceptible to cervical cancer, and chlamydia can lead to infertility. A 2004 study, involving the same group of adolescent girls, found that those who viewed an interactive sex education DVD created by Carnegie Mellon researchers were more likely to become abstinent than ...

Spinal cord bridge bypasses injury to restore mobility

...d animal study, 12 rats had spinal injuries at the cervical level 3 (C3) that resulted in impaired motor functions to their right side limbs. The animals had trouble moving, climbing or grooming. Combining the old with the new, the researchers grafted a 1.5 centimeter piece of the tibial branch of he sciati...

Gene screen for breast cancer better than pathologist's 'eye'

...uch as lung, head and neck cancers, pancreatic and cervical cancers." Pathologists look for telltale shapes of cells to determine if cancer is present, but molecular changes in cells, especially for early cancers, are beyond the reach of even the most powerful microscopes. Sukumar's test searches for un...

One therapeutic dose of radiation causes 30 percent spongy bone loss in mice

...menopausal women who received pelvic radiation for cervical and colorectal cancer increased their bone fracture risk by 60%. Radiation following anal cancer increased the risk of fracture by 200%, he said. Astronauts lose 2% of bone mass for each month they are exposed to the effects of microgravity. So far...

Higher risk for cervical cancer seen among women infected with multiple HPV types

Although doctors have known that the cervical tissue at the opening to the womb can harbor multi...the first to document that the risk for developing cervical cancer, the second most common form of cancer in women worldwide, is higher in females infected with...

Targeted virus compels cancer cells to eat themselves

...ents that the virus kills human prostate and human cervical cancer cells while sparing normal tissue. In addition to demonstrating the therapeutic potential of the virus, called hTERT-Ad, Kondo says the international research team also clarified the mechanism by which such conditionally replicating adenovi...

Handling HPV vaccines and screening: The views of 100 authors

...on of HPV-based screening technology, the field of cervical cancer prevention is expanding into new areas of i...vaccine for both genders towards the prevention of cervical cancer. "An unprecedented and phenomenal challenge for Public Health in the 21st century", according...

High HPV concentrations combined with smoking significantly raise risks of cervical cancer

...tion with high levels of the virus associated with cervical cancer can increase cancer risk by as much as 27 t...iewed the medical exams of women with non-invasive cervical cancer in situ (the most common type) and cancer-free women in one of the largest studies to date to...

Male circumcision reduces HIV risk, study stopped early

..., fewer urinary tract infections, and less risk of cervical cancer in the partners of circumcised men." The armamentarium of HIV prevention strategies is very small, according to Bailey. The only other strategy proven effective is the use of antiretroviral drugs to reduce transmission from mother to child...

What does the public really know about HPV?

...certain "high risk" types have been shown to cause cervical cancer. Despite recent advances in the detection ... prevention of HPV, the link between the virus and cervical cancer is not well known to the public. In June 2006, the Food and Drug Administration (FDA) approv...

Encouraging results in pancreatic cancer research

...esides pancreatic cancer, including colon, breast, cervical and bone (osteogenic sarcoma) cancers. These peptides kill cancer cells that do not even contain native p53 protein and therefore appear to have a wide applicability in treating a variety of human cancers. ...

Temple University Hospital investigates treatment for cervical dysplasia

... effectiveness of an investigational treatment for cervical dysplasia. According to the American Cancer Societ...mately 500,000 women are diagnosed with high-grade cervical dysplasia each year, with roughly 10,000 cases progressing to cervical cancer. For numerous women a...

Creating new life forms that may help eradicate cancer affecting women

...ancers. The company is also currently testing its cervical cancer vaccine, Lovaxin C, in phase I/II trials. ...

How T lymphocytes attack

...ith choroidal melanoma and the other in women with cervical cancer. ...

New test for most virulent HPV strains under study

...rains of human papillomavirus responsible for most cervical cancers is under study. The molecular assay uses a cervical scraping, like that for a liquid-based Pap smear, to test for HPV types 16 and 18, responsible for 7...

Antibody signal may redirect inflammation to fuel cancer

...e already know that inflammation accelerates skin, cervical and colon cancer, and most likely also lung and br...rus (HPV), a pathogen that is known to cause human cervical cancer. By comparing cancer progression in these mice compared with gene "knock-out mice" that lacke...

Scientists perform 'tricky' operation

...h pre-term birth, low infant birth weight and some cervical cancers. "Alarmingly, trichomoniasis is not considered a notifiable disease." Routine gynaecological check-ups do not test for this particular STI and the infection does not require public health notification. Because of this, and also due t...

Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find

... quality with aging (2) increasing prevalence of cervical spinal stenosis with older age (3) an increased rate of motor vehicle accidents per mile driven It is also believed that these older patients have an increased risk of mortality due to their concurrent medical illnesses, as well as their limite...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...human papillomavirus vaccine, developed to prevent cervical cancer, shows that the vaccine continues to protec...thought to cause nearly 72 percent of all cases of cervical cancer. At over five years into the study’s follow-up, the researchers found that approximately ...

Synthetic peptide targets latent papilloma virus infections

...pilloma virus (HPV) infections, the major cause of cervical cancer, a new discovery by University of Californi...HPV infection, while 10,000 women annually develop cervical cancer, more than 90 percent of which is caused by HPV. Four thousand women die of cervical cancer e...

Study shows continued success for new HPV vaccine against virus responsible for cervical cancer

A new vaccine aimed at preventing cervical cancer is nearly 100 percent effective against the...papillomavirus (HPV) responsible for most cases of cervical cancer. Results of a nationwide study of the vaccine will be published in the May 9 issue of the New...

Warts vaccine -- 1 of many in pipeline

...aim to use a tweaked version of Professor Frazer’s cervical cancer vaccine to treat genital warts. Professor Frazer said this vaccine could be one of the first made locally at the biopharmaceutical production centre, which received $100 million in last night’s Federal Budget. The centre, called the Tran...

Researchers use MRI to predict recovery after spinal cord injury

...hlings’ study included 100 patients with traumatic cervical SCI. The group consisted of 79 men and 21 women between the ages of 17 and 96. Complete motor and sensory SCI was seen in 26 patients, incomplete SCI was seen in 51 patients, and 22 patients were neurologically intact upon admission. One patient coul...

Cellular message movement captured on video

...or example, human papilloma virus, which can cause cervical cancer, makes a protein that binds to paxillin and that interaction may contribute to the carcinogenic potential of the sexually transmitted virus. Chien and Hu obtained cells for their most recent study from the inner membranous lining of a cow a...