Hopkins researchers piece together gene 'network' linked to schizophrenia
... of proteins had discovered that one of them, BBS4, also is found near the centrosome and also binds to PCM1. "But we weren't thinking schizophrenia at the time ... The researchers then asked if the failure of PCM1 recruitment to the centrosome in mice lacking either DISC1 or BBS4 affects brain development. To do ...The cooperative view: New evidence suggests a symbiogenetic origin for the centrosome
... of the National Academy of Sciences, the Alliegros give evidence that the centrosome evolved through symbiogenesis in which previously independent organisms ... visiting investigator at the MBL, is acknowledged for providing the centrosome preparation for the original RNA extractions as well as advice and ...Vanderbilt scientists invent world's smallest periscopes
... cells because it can follow them in three dimensions," says Janetopoulos. Researchers in his lab have used the wells to track the 3D position of the centrosome the specialized region of a cell next to the nucleus that is the assembly point where the microscopic polymer tubes that serve as part of the cell's ...Surprising origin of cell's internal highways
... at a structure near the cell's nucleus called the centrosome or microtubule-organizing center (MTOC). ... originate from non-centrosomal structures, the centrosome has been considered the main origination point ... precisely, it is hard to distinguish between the centrosome and Golgi." To get a close look, Kaverina ...RNA found in the cellular centrosome of surf clams
... "Although the possibility of DNA inside the centrosome of the cell has been ruled out by others' ... least five specific forms of RNA in the clam cell centrosome which could be related to structure, encoding of ... The specific role or function of the RNA in the centrosome and its possible involvement in the development ...Researchers now able to look deep into heart to view triggers of a heart's beat
... centrosomes through duplication, but there is no centrosome in the egg that could give rise to new ones. We ... cells gets a complete set of chromosomes. The centrosome contains about a hundred different proteins, ... the egg gets fertilized they don't use them--the centrosome from the sperm is used preferentially." ...Insects that produce males from unfertilized eggs reveal a surprising cellular feat
... centrosomes through duplication, but there is no centrosome in the egg that could give rise to new ones. We ... cells gets a complete set of chromosomes. The centrosome contains about a hundred different proteins, ... the egg gets fertilized they don't use them--the centrosome from the sperm is used preferentially." ...Double trouble: Cells with duplicate genomes can trigger tumors
... called Barrett's esophagus. In addition to the extra chromosomes, the "double value" or "tetraploid" cells also duplicate a cell structure called the centrosome that plays a role in maintaining a stable genome. The extra centrosomes may be at the root of the cancer-triggering process. Once the genetic ...