Advances in lung cancer research announced at conference
... an Associate Investigator in TGen's Cancer and cell
Biology Division and Director of Thoracic ... cancer from spreading to the brain. In non-small cell
lung cancer (NSCLC), brain metastasis is a ... brain metastasis in patients with non-small cell
lung cancer," Dr. Weiss said. "Identifying the ...
New cancer drug delivery system is effective and reversible
... a new cancer drug delivery system that, in cell
culture, achieves all of the above. The findings ... Ideally the antibody will bind to a cancer cell
receptor so that it can deliver the liposome and ... such folate, a vitamin, also work as cancer cell
targeting agents, but those now in use are not as ...
Wastewater produces electricity and desalinates water
... Penn State
The team modified a microbial fuel cell
-- a device that uses naturally occurring ... is proof of concept."
A typical microbial fuel cell
consists of two chambers, one filled with ... University, Beijing, changed the microbial fuel cell
by adding a third chamber between the two ...
'Green' energy from algae
... are developing closed photo-bioreactors and novel cell
Microalgae are ... extraction methods to obtain a maximum amount of cell
constituents from the algae that can be used for ... very short term. This causes a perforation of the cell
membrane and the constituents are released."
New stem cell research could reduce number of animal experiments
... of Bath are embarking on a project to use stem cell
technology that could reduce the number of animal ...
She said: "These are exciting times for stem cell
research and there is tremendous potential in the iPS cell
technology both for medical applications and in ...
La Jolla Institute discovers novel tumor suppressor
... Center and a professor in Salk's Molecular and cell
Biology Laboratory, called the finding an ... published online today in the journal Cancer cell
in a paper entitled "Tumor Suppression by ... than can switch on many genes known to control cell
proliferation, survival and, in the case of ...
Stem cell 'daughters' lead to breast cancer
... to normal luminal progenitor cells than any other cell
type in the breast. This places the spotlight on ... faulty DNA repair and expanded luminal progenitor cell
numbers ultimately resulting in breast cancer in ... c-KIT is a key marker of the luminal progenitor cell
and I expect we will see an increase in ...
Got zinc? New zinc research suggests novel therapeutic targets
... volunteers to assess the effects of zinc on T cell
activation. After isolating the T cells from the ... than those from the placebo group. Specifically, cell
activation stimulated the zinc transporter in T ... "ZIP8," which transports stored zinc into the cell
cytoplasm where it then alters the expression of ...
Study links virus to some cases of common skin cancer
... tissue samples from 58 people with squamous cell
carcinoma (SCC), a highly curable form of skin ... play a role in causing some cases of squamous cell
carcinoma," says principal investigator Amanda E. ... was first discovered in patients with Merkel cell
carcinoma, a rare, aggressive skin cancer that ...
Little-known protein found to be key player
... McNew, associate professor of biochemistry and cell
biology at Rice University. "In fact, that's ... that happens thousands of times a second in every cell
of our bodies.
"It is fitting that the ... tests on purified proteins, live fruit flies and cell
cultures, the Italian and U.S. teams examined the ...
Reprogramming human cells without inserting genes
... LSBC, has discovered a novel way to turn on stem cell
genes in human fibroblasts (skin cells) without ... its findings in the paper "Induction of Stem cell
Gene Expression in Adult Human Fibroblasts ... be beneficial in development of patient-specific cell
therapy approaches," the authors wrote in the ...
Stem cell research: From molecular physiology to therapeutic applications
... Stem cell
research promises remedies to many devastating ... to summarize their pioneering works in the stem cell
Since 2001, Dr. Alex Yu Zhang ... Medical University in Beijing and is Director of cell
Therapy Center at Xuanwu Hospital. His current ...
Fox Chase researchers uncover one force behind the MYC oncogene in many cancers
... the DLX5 gene gets flipped around during cell
division cooperates with another known oncogene, ... performed in mouse cancer models and in human cell
"While MYC has a definite role in ... in decreased expression of MYC and reduced cell
proliferation. By adding an overabundance of MYC, ...
Comprehensive look at rare leukemia finds relatively few genetic changes launch disease
... myeloid progenitors to convert them from a normal cell
to AML," the authors noted, referring to several ... about what it takes to transform a normal cell
into a cancer cell. "The complement of genetic ... from normal controls and allow the uncontrolled cell
division that is a hallmark of cancer. Downing ...
Study reveals a reprogrammed role for the androgen receptor
... a protein ignition switch for prostate cancer cell
growth and division is a master of adaptability. ... receptor of androgen hormones, thereby halting cell
proliferation, the receptor manages to find an ... from androgen-dependent to androgen-independent cell
growth occurs, in part, because the androgen ...
Placenta-derived stem cells may help sufferers of lung diseases
... team, publishing in the current issue of cell
Transplantation (18:4), which is now available ... to evaluate the effects of fetal membrane-derived cell
transplantation in chemically-treated (bleomycin) ... fetal membrane-derived cells may prove useful for cell
therapy of fibrotic diseases in the future," ...
Cancer's distinctive pattern of gene expression could aid early screening and prevention
... finding patterns of genes that regulate healthy cell
differentiation are shut off in cancers. "These ... but once you have committed to become a certain cell
type, like a skin cell, you need to turn the gene ... they also want to turn off, like ones that tell a cell
to differenitate. For ...
Scientists track impact of DNA damage in the developing brain
... Ph.D., a member of St. Jude Genetics and Tumor cell
Biology, said the work provides a new model for ... the damage triggered apoptosis, or programmed cell
death. But the findings suggested the greatest ... pathway and blocked the cells from completing the cell
cycle. "The cells appear to undergo permanent ...
Scientists closer to making implantable bone material, thanks to new research
... how to grow replacement bones with stem cell
technology, thanks to research published today in ... types of bone cells and stem cells. All of these cell
types are attracting considerable interest as ... three different commonly used clinically relevant cell
types and have discovered significant differences ...
Protein that promotes cancer cell growth identified
... to play a major role in promoting programmed cell
death (apoptosis), helps relay signals that can ... from epidermal growth factor (EGF) that cause cell
division and invasion. The researchers also ... through the protein kinase Src to the master cell
proliferation regulator protein, MAPK. This same ...
Grant supports LSUHSC research on how like cell receptor systems determine very different functions
... on the mechanism by which seemingly similar cell
receptor systems determine quite different ... such as proliferation, differentiation and cell
migration," notes Dr. Catling. "We hypothesize ... that functions in the intracellular movement and cell
division activity of growth factor receptors as a ...
Sticky protein helps reinforce fragile muscle membranes
... the sturdy basal lamina reinforces muscle cell
membranes and keeps small tears from bursting ... basal lamina interaction, rendering the cell
membrane susceptible to rupture.
"Considering how essential cell
membranes are for life, these barriers are ...
New windows opened on cell-to-cell interactions
... Applying biological molecules from cell
membranes to the surfaces of artificial materials ... colleagues suggest that putting lipids and other cell
membrane components on manufactured surfaces ...
Controlling molecular orientation from cell
In a paper appearing online in the ...
A genetic basis for schizophrenia
... of cells and function properly. Disruption of cell
migration can lead to inappropriate cell
development and function, resulting in disease. ... are multi-potent cells that give rise to multiple cell
types including craniofacial cartilage and the ...
International research team seeks to unravel flatworm regeneration
... which may play a role in regeneration and stem cell
function, Nikolaus Rajewsky from the MDC points ... many genes specifically linked to planarian stem cell
biology and regeneration are conserved in humans. ... insights into human regeneration and stem cell
biology, the researchers are convinced.
Skin-like tissue developed from human embryonic stem cells
... a single source of hESC can provide the multiple cell
types needed to interact within a ... chemical nutrients and specialized surfaces for cell
attachment, an hES cell
line (H9) was directed to form two distinct ...
New research finds possible genetic link to cause of pregnancy loss and disorders
... the research team found that if a mother's egg cell
has a mutation in just one copy of a gene, called ... are properly divided during meiosis, the cell
division process that enables a stem cell
to become an egg. This checkpoint hiccups when ...
Iowa State University researchers develop process for 'surgical' genetic changes
... a break is made in the DNA of that gene. When the cell
begins to heal itself, existing DNA can be ... can be added near the break site. Afterward, the cell
carries the genetic change and passes the change ... "It's just that you have three meters of DNA in a cell
if you unwound it. Putting the break where you ...
UCLA researchers discover new molecular pathway for targeting cancer, disease
... in the maintenance of tissue integrity and stem cell
generation. When stimulated in an unregulated ... researchers. How LXR was able to inhibit tumor cell
growth by impeding the Hh pathway was previously ... Hh pathway activity and for targeting various cell
types, including cancer cells, which may provide ...
Chasing tiny vehicles
... the activation of a transported gene inside a cell
for example. Under the direction of LMU Munich ... separate phases: how the particles reached the cell
membrane, came to rest there and then ultimately ... them and quickly transports them towards the cell
nucleus the ultimate target for the gene.
LincRNAs serve as genetic air-traffic controllers
... in many biological processes, including stem cell
cycle regulation, and the innate immune response. ... know to regulate one genomic location in a brain cell
and regulate a different genomic region in a ...
Flexible neck in cell-receptor DC-SIGN targets more pathogens
... apart. In the current work, the surfaces were cell
receptor DC-SIGN and a target membrane decorated ... protein binds to a pathogen, binding sites on the cell
receptor rearrange slightly, to adapt to the ... the molecule's binding sites away from the cell
surface," Leckband said. "A rigid presentation of ...
Study by NTU professors provides important insight into apoptosis or programmed cell death
... This process known as 'apoptosis' or programmed cell
death, is a normal process in the human body ... (i.e. 'anti-factors' that are necessary to keep a cell
alive) are no longer able to enter the cell's ... a role in a great many diseases. When programmed cell
death does not work right, cells that should be ...
New technique can fast-track better ionic liquids for biomass pre-treatments
... Based on the natural auto-fluorescence of plant cell
walls, this technique enables researchers for the ... observed a rapid swelling of the secondary plant cell
walls within three hours of exposure at ... fiber that gives strength and structure to plant cell
walls the subsequent addition of an ...
A matter of density, not quantity
... of quorum sensing, which cells use to "sense" cell
density, is triggered when the concentration of ... that quorum sensing is also activated by a single cell
if the cell
finds itself in an extremely enclosed space, ...
Telomeres resemble DNA fragile sites
... led by Titia de Lange, head of the Laboratory of cell
Biology and Genetics, and first author Agnel ...
The work, published in the July 10 issue of cell
, began when Sfeir deleted TRF1 and saw that the ... elongates telomeres, which shorten during every cell
division. The second problem posed by telomeres, ...
... are able to assemble into clusters that direct cell
movement to select chemicals in their ... single proteins. With PALM, we can examine a cell
and see single proteins, protein dimers, and so ... display a nonrandom, periodic distribution in the cell
"Chemotaxis proteins cluster into ...
Work in mice will contribute to the study of hereditary diseases that lead to blindness
... Santos Carro , researcher of the Department of cell
Biology of the University of Granada , is based on the study of microglial cells, a type of cell
of the Nervous System that develop a phagocytic ... meetings: VIII European Meeting on Glial cell
Functions in Health and Disease (Londres), VII ...
Plant protein 'doorkeepers' block invading microbes, study finds
... one makes use of receptor proteins outside the cell
to recognize specific molecular features of an ... the other branch uses similar proteins within the cell
to recognize an invading microbe during the ... in the permeable plasma membrane that encases the cell
on the inside of ...
Protein can help cells or cause cancer, Purdue researcher finds
... scientist has discovered a key process in cell
growth that can lead to the formation of tumors. ... the polo-like kinase 1, or Plk1, molecule during cell
growth, as well as a shortage of the p53 ... approach to treating that cancer."
growth, Plk1 uses its protein kinase activity ...