Carcinogen in Biological News

Improved method developed to test carcinogen risk

... found that acceptable levels of at least one carcinogen may be 500 to 1,500 times higher than is ... that are done using high concentrations of a carcinogen a common practice made necessary by cost and ... very significant, Bailey said, since much of the carcinogen research around the world is based on this. ...

Glutamine supplements show promise in treating stomach ulcers

... finding in the clinical setting. " H. pylori bacteria infect more than half of the world's population and were recently identified as a Group 1 carcinogen by the World Health Organization," she adds. "Approximately 5.5 percent of the entire global cancer burden is attributed to H. pylori infection ...

Gutsy germs succumb to baby broccoli

... says, which confirms previous findings for a role of Nrf2 in protection against H. pylori -induced inflammation and gastritis. Classified a carcinogen by the World Health Organization, H. pylori is a gastrointestinal tract germ that manages to thrive in the lining of the stomach despite the ...

More than skin deep: There's no such thing as a 'safe' suntan, researchers warn

... including causing DNA damage, photoaging (damage to the skin from chronic exposure to sunlight) and skin cancer. UV radiation is the most ubiquitous carcinogen (cancer-causing agent) for humans, in whom skin is the organ most commonly affected by cancer. Although more research is required, published data ...

New and revised limits ensure safety in the workplace

... of many biomolecules in the body is very useful for natural substances such as rubber and for many aromatic compounds in industry, is known to be a carcinogen and is able to modify germ cells. Following a comparison with the so-called endogenous concentration however, i.e. that formed as part of the body's ...

Early treatment of stomach infection may prevent cancer

... Although H. pylori infection is now recognized as the major cause of both peptic ulcers and gastric cancer, and has been classified as a group I carcinogen by the World Health Organization, physicians are not sure whom to screen and treat with costly antibiotics, aside from first degree relatives of ...

Impacts of fossil fuels on fish and people

... of 1989. Certain PAHs were recognized as carcinogenic more than a century ago, but a class of PAHs with a different structure was ruled out as a carcinogen and was largely ignored. What Incardona learned was that this class of PAHs, also found in oil, is toxic to the developing hearts of fish. This ...

Fighting pollution the poplar way: Trees to clean up Indiana site

... of the surface, making it accessible to poplar roots, he said. TCE, the most common groundwater pollutant on Superfund sites, is a probable human carcinogen and causes various health problems when present in sufficiently high levels in water or air. Meilan said planting transgenic trees in the field ...

Scientists develop a fast system to detect metal concentrations in iron and steel industry workers

... Gil Fernndez also discussed the poisonous character of everyday items such as batteries. For example, the cadmium in these batteries is a potential carcinogen which can produce lung and testicle cancers among others hence the importance of an adequate waste treatment system. Furthermore, Gil Fernndez ...

American Chemical Society's Weekly PressPac -- Aug. 15, 2007

... to coffee. The highest levels are in fried and baked products such as potato chips and other snack foods. Although classified as a probable human carcinogen on the basis of animal studies, there is currently no consensus on dietary acrylamides risks to human health. With food safety authorities in Europe ...

New cigarette designs don't offer lower predicted cancer risks

... potency of those known carcinogens, and you add up all the predicted carcinogen activity, you don't come close to what's observed for the smoking-related ... reduce the risks of smoking," she said. Pankow's group examined carcinogen deliveries from 26 brands of conventional "regular," "light" and ...

Mailman School of Public Health researchers report blood DNA can be early predictor of liver cancer

... mold contaminant sometimes found in peanuts and corn; polycyclic aromatic hydrocarbons, ubiquitous environmental contaminants; and 4-aminobiphenyl, a carcinogen found in cigarette smoke, are also associated with the development of HCC. While HCC incidence is highest in East Asia and Sub-Saharan Africa, it is ...

Vaccination with embryonic stem cells prevents lung cancer in mice

... them afterwards, ESCs were 80% effective in preventing tumour growth and ESCs + STO/GM-CSF were 100% effective. In mice subsequently exposed to a carcinogen that causes lung cancer (3-methylcholanthrene followed by repetitive dosing with butylated hydroxytoluene), ESCs resulted in 60% of mice remaining ...

Cycles of cell death, proliferation key to liver cancer

... Their research showed that the absence of IKKƒÒ in hepatocytes led to increased c-Jun N-terminal kinase (JNK) activation after exposure to a chemical carcinogen used to elicit liver cancer in mice. Importantly, deletion of the gene that codes for the major isoform of JNK in liver cells, JNK1, prevented the ...

Building a better mouse model of lung cancer: FHIT counts

... both copies. They also established a control group of normal mice that had both copies of the gene. They exposed all the mice to NNK, a powerful carcinogen commonly found in tobacco smoke that researchers believe plays a major role in human lung cancer. They discovered that while mice deficient in the ...

Zebrafish may hold key to improved cancer research

... for cancer research. Those studies, among others, helped to determine that aflatoxin contaminants which can be found in some foods are a powerful carcinogen ?and are still a major cause of liver cancer in some developing nations. Zebrafish, however, are a fascinating species because the fish embryos ...

Change in gene may be underlying molecular defect in some colorectal cancers

... similar genetic abnormalities, such as those that occur in patients who are genetically predisposed to a cancer or those who undergo an exposure to a carcinogen such as tobacco smoke. However, how the field defect may arise in most sporadic cancers in unclear. In colorectal cancer, the DNA repair gene O 6 ...

Red delicious, Northern Spy apples have most antioxidants, chemists find

... drugs, researchers say. In March, these findings were presented at the ACS national meeting in San Diego. * Breast cancer. Rats exposed to a known carcinogen and then fed the human equivalent of one, three or six apples a day respectively over 24 weeks were up to 44 percent less likely to develop breast ...

NYU and MSKCC research provides model for understanding chemically induced cancer initiation

... (composed only of one carbon and three hydrogen atoms) on a cytosine base adjacent to the damaged site. Without this methyl group, the bulky chemical carcinogen resides at an external binding site in the minor groove of the DNA double helix. However, in the presence of this single methyl group, it assumes an ...