capillary

Open microfluidic and nanofluidic systems

...w been developed. This theory addresses the strong capillary forces between substrate material and liquid and t...s constraint is a direct consequence of the strong capillary forces that dominate in the micro- and nanoregime and can be formulated in a quantitative way using ...

Life detection instrument passes key test on road to Mars

...igns of life. The experiment uses state-of-the-art capillary electrophoresis arrays, novel micro-valve systems ...the case on Mars, the microfluidic channels in the capillary disks don't get clogged as readily as they do when used to test samples in Berkeley with its high bi...

New mitochondrial DNA gene chip may be early cancer diagnosis tool

...nd that full mitochondrial genome sequencing using capillary electrophoresis detected mtDNA changes associated ...h early cancer. In ongoing work, NIST is comparing capillary electrophoresis methods with a newly developed DNA sequencing chip. The mtDNA chips are a promising ...

Beetle-inspired switch uses water for bonding

...ectricity pulls the exposed water back through the capillary pores. With millimeter-sized water droplets and micron-sized pores, 5 volts can turn the switch on in one second. At the same time, the researchers predict that smaller droplets will require less energy to move and have faster switching times. Stee...

NHGRI expands effort to revolutionize sequencing technologies

...roduct to Sanger sequencing and a highly parallel, capillary electrophoresis separation system. Greg Kellogg, ...ncing and PCR as compared to that attainable using capillary electrophoresis systems. To do so, it will miniaturize and integrate current sequencing technologies...

Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy

...AV-8, is particularly efficient at penetrating the capillary barrier, making it a good candidate for whole-body gene delivery. In this study, they tested AAV-8 in an animal model of human muscular dystrophy called limb girdle muscular dystrophy, or LGMD. In human LGMD, defects in a muscle cell membrane protein...

Plant genes identified that can form basis for crops better adapted to environmental conditions

... the genes that are essential for the formation of capillary roots. For the first time, they are unraveling the... further growth and development. The mystery of capillary root formation Root systems absorb nutrients and anchor plants in the soil − two crucial fun...

Cellular scale drug delivery from the inside out

... channels running completely through them. Through capillary action, the spheres can soak up molecules of the drug to be delivered. When the channels are filled, the ends of channels are "capped" to safely seal the drug inside. Once the caps are in place, the nanospheres are "washed" to remove the drug from th...

MIT designs portable 'lab on a chip'

...ly with miniaturization. The second approach is capillary electro-osmosis, where flow is driven by an electr...acing electrodes at each end of the channel, as in capillary electro-osmosis, the voltage can be lowered substantially with alternating current (AC) applied at c...

Spelling out cancer on the nanoscale

...em physically separates the proteins in very small capillary tubes and then uses antibodies for protein detection. It was also tested on human lymphoma samples. In previous work, the Felsher group had shown that inactivating MYC induces sustained tumor regression in mice. The researchers decided to test...

Interaction between lymph and liver cells may affect immune response

...cells (gossamer-like structures that form the rich capillary network of the liver) and are perforated by fenestrations, or openings. The researchers hypothesized that the fenestrations could provide a portal through which liver cells and T cells could interact or that the interaction could take place across ga...

Cancer-killing invention also harvests stem cells

...the skin. Some of the blood flow would bypass the capillary bed and instead go into the shunt, which could remain implanted for many weeks, continually removing and killing cancer cells. King's first targets are colorectal cancer and blood malignancies such as leukemia....

Now, self-healing materials can mimic human skin, healing again and again

...oating and substrate. Healing agent moves from the capillary into the crack, where it interacts with catalyst particles. If the crack reopens under additional stress, the healing cycle is repeated. “Ultimately, the ability to achieve further healing events is controlled by the availability of active catalyst...