Cancer in Biological News

Advances in lung cancer research announced at conference

... two significant advances in treating lung cancer at an international cancer research conference. Dr. Weiss, M.D., an Associate Investigator in TGen's cancer and Cell Biology Division and Director of ...

Navigating in the ocean of molecules

... . Tracking down new active agents for cancer or malaria treatment could soon become easier - ... for the development of active agents for use in cancer treatment and malaria. ( Nature Chemical Biology ... seen as a promising approach to the treatment of cancer and malaria. An even more detailed search can ...

New cancer drug delivery system is effective and reversible

... CHAMPAIGN, Ill. For cancer drug developers, finding an agent that kills ... researchers report that they have assembled a new cancer drug delivery system that, in cell culture, ... When linked to molecules that target receptors on cancer cells, liposomes can enter and dump their ...

Protein handlers should be effective treatment target for cancer and Alzheimer's

... AUGUSTA, Ga. cancer and Alzheimer's have excess protein in common and ... Dimitrios Moskofidis have received two National cancer Institute grants totaling nearly $3 million and a ... the exact role molecular chaperones play in cancer and Alzheimer's should lead to better ways to ...

Moving to the US increases cancer risk for Hispanics

... incidence rates of certain cancers and worse cancer outcomes if they live in the United States, than ... are not all the same with regard to their cancer experience," said Paulo S. Pinheiro, M.D., Ph.D., ... of Medicine. "Targeted interventions for cancer prevention and control should take into account ...

More than half of Texas physicians do not always recommend HPV vaccine to girls

... recommendations. The survey was published in cancer Epidemiology, Biomarkers & Prevention , a journal of the American Association for cancer Research. "Two years after the FDA approved ... Vernon, who is also an editorial board member of cancer Epidemiology, Biomarkers & Prevention. ...

Women often opt to surgically remove their breasts, ovaries to reduce cancer risk

... Many women at high risk for breast or ovarian cancer are choosing to undergo surgery as a precautionary measure to decrease their cancer risk, according to a report in cancer Epidemiology, Biomarkers & Prevention , a journal ...

Pitt researchers find promising candidate protein for cancer prevention vaccines

... a tumor challenge in which they were exposed to a cancer cell line that overproduced it, explained senior ... trial of a cyclin B1 treatment vaccine in lung cancer patients, and she plans to assess it in the ... a protein that is abnormally produced in colon cancer and in precancerous polyps. The MUC1 ...

The way you eat may affect your risk for breast cancer

... much you eat, if mice studies are any clue. cancer researchers have long studied the role of diet on breast cancer risk, but results to date have been mixed. New findings published in cancer Prevention Research , a journal of the American ...

La Jolla Institute discovers novel tumor suppressor

... Hunter, Ph.D., director of the Salk Institute cancer Center and a professor in Salk's Molecular and ... are being published online today in the journal cancer Cell in a paper entitled "Tumor Suppression by ... of STAT5." Researchers from UC San Diego cancer Center, University of Alabama and the University ...

Stem cell 'daughters' lead to breast cancer

... Lindeman from the institute's Victorian Breast cancer Research Consortium Laboratory have discovered ... a major shift in the way scientists think breast cancer develops. Dr Visvader said it had been thought ... Dr Lindeman, who also heads the Familial cancer Centre at the Royal Melbourne Hospital, said that ...

Race/ethnicity, family income and education associated with sugar consumption

... 2005 US National Health Interview Survey (NHIS) cancer Control Supplement, investigators from the National cancer Institute (NCI), the National Heart, Lung, and ... health behaviors and conditions. Periodically, a cancer Control Module (CCM) is included to obtain ...

UC San Diego engineer provides insights to decades-old DNA squabble

... For example, he said, lots of diseases including cancer are directly linked to abnormal regulation of ... into biology," he added. "When we talk about cancer and its link to abnormal gene regulation, we have ... oncogenic or tumor suppressor genes that lead to cancer or you could have abnormalities in the proteins ...

Antibody targeting of glioblastoma shows promise in preclinical tests, say Lombardi researchers

... Washington, DC cancer researchers at Georgetown University's Lombardi Comprehensive cancer Center have successfully tested a small, ... Lombardi in 1989, he worked at the National cancer Institute with other investigators hunting for ...

Study links virus to some cases of common skin cancer

... virus discovered last year in a rare form of skin cancer has also been found in people with the second most common form of skin cancer among Americans, according to researchers at the Ohio State University Comprehensive cancer Center - ...

Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth

... DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in ... within 18 to 24 months, according to a report in cancer Research , a journal of the American Association for cancer Research. Although early stage ...

A crystal ball for brain cancer?

... himself lucky. When his aggressive brain cancer returned after chemotherapy and radiation, his ... Subsequent brain scans show no trace of his cancer at all. The former marathon runner, ordained ... tumor creates an independent blood supply. cancer cells secrete a growth factor called VEGF that ...

Fox Chase researchers uncover one force behind the MYC oncogene in many cancers

... gene crucial for embryonic development, promotes cancer by activating the expression of the known oncogene, MYC, according to researchers from Fox Chase cancer Center. Since the DLX5 gene is inactive in normal ... with another known oncogene, AKT2, to drive cancer in mice. In the current paper, the researchers ...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

... from a clinical study showing patient-specific cancer vaccines derived from patients' own cancer cells and immune cells were well tolerated and ... was published in the June 2009 issue of cancer Biotherapy and Radiopharmaceuticals and was ...

Comprehensive look at rare leukemia finds relatively few genetic changes launch disease

... mistakes in the genetic blueprint, suggesting the cancer arises from just a handful of missteps, according ... what it takes to transform a normal cell into a cancer cell. "The complement of genetic lesions varies ... identified that harbor known and potential new cancer genes. The study also reports cryptic ...

Study reveals a reprogrammed role for the androgen receptor

... receptor a protein ignition switch for prostate cancer cell growth and division is a master of ... growth route. A new study by Dana-Farber cancer Institute and Ohio State University scientists ... be harder to stop. "The evolution of prostate cancer from an androgen-dependent state to an ...

Cancer's distinctive pattern of gene expression could aid early screening and prevention

... order, says Dr. Kapil Bhalla, director of the MCG cancer Center, Cecil F. Whitaker Jr., M.D./Georgia Research Alliance Eminent Scholar in cancer and Georgia cancer Coalition Scholar. DNA methylation is a piece ...

Most older long-term cancer survivors have poor health habits

... A new study finds that most older long-term cancer survivors who are interested in diet and exercise ... Published in the September 1, 2009 issue of cancer , a peer-reviewed journal of the American cancer Society, the research indicates that greater ...

Protein that promotes cancer cell growth identified

... (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade ... tissues. The study was published in the journal cancer Research on June 15. The team of scientists, ... Vuori, M.D., Ph.D., professor and director of the cancer Center at Burnham, showed that Caspase-8 caused ...

Newly discovered gene fusion may lead to improved prostate cancer diagnosis

... The results may lead to more accurate prostate cancer testing and new targets for potential treatments. ... genes -- may be at the root of what causes cancer cells to grow more quickly than normal cells. ... target for drug therapies. "The prostate cancer gene fusions, and proteins they produce, are ...

SRI announces selection by the National Cancer Institute as a Chemical Biology Consortium center

... announced today that SRI's Center for cancer Research was selected by the National cancer Institute (NCI) for a leading role in the ... discovery partnership focused on advancing new cancer therapeutics active against novel molecular and ...

$2 million grant aids study of lung cancer in people who never smoked

... Medical Center are among an elite group of cancer scientists to share a $2 million grant to find biomarkers for lung cancer that develops in people who have never smoked. The National cancer Institute's Early Detection Research Network ...

UCLA researchers discover new molecular pathway for targeting cancer, disease

... that can also stimulate the development of cancer and other diseases. The findings may lead to new ... and for targeting various cell types, including cancer cells, which may provide important clues as to ... Medical Institute, an expert on Hh signaling in cancer development, noted the importance of the UCLA ...

Chasing tiny vehicles

... that could be used, among other things, in cancer therapy. This approach should also allow a better ... Magnetic particles have already been tried in cancer therapies: They have been administered by ... the efficiency of their transport and uptake by cancer cells. So far, only the appearance or absence ...

2 Fred Hutchinson Cancer Research Center scientists receive Presidential Early Career Award

... Obama today announced that two Fred Hutchinson cancer Research Center investigators have been awarded ... supports her work, is an associate member of the cancer Prevention Program within the Hutchinson Center's ... Peters studies the link between nutrition and cancer prevention particularly how the interplay of ...

AACR applauds nomination of Francis S. Collins, M.D., Ph.D., to be the new NIH director

... WASHINGTON, D.C. The American Association for cancer Research applauds President Obama's nomination of ... Ph.D., president of the American Association for cancer Research. "His leadership of the National Human ... collaborations with scientists at the National cancer Institute on ...

Systems biology recommended as a clinical approach to cancer

... approach in developing a comprehensive view of cancer diseases, which will help researchers better understand the complex processes related to cancer progression, diagnosis, and treatment. Systems ... and predict the effect of interventions, such as cancer treatments. "One of the goals of this paper is ...

2 reproductive factors are important predictors of death from ovarian cancer

... found that survival among women with ovarian cancer is influenced by age of menarche and total number ... may influence the prognosis after an ovarian cancer diagnosis. Results of this study are published in cancer Epidemiology, Biomarkers & Prevention , a journal ...

Possible drug target found for one of the most aggressive breast cancers

... cancers have few treatment options. "Breast cancer mortality rates are actually declining, but the ... the development of an aggressive form of breast cancer known as basal breast cancer. "Met has ... Dr. Vande Woude's laboratory at the National cancer Institute demonstrated that inappropriate levels ...

Genetic factors implicated in survival gap for breast, ovarian or prostate cancer

... patients with breast, ovarian, and prostate cancer tend to die earlier than patients of other races ... to examining racial and ethnic disparities in cancer outcome and in cancer survivorship, was the senior author of the ...

Protein can help cells or cause cancer, Purdue researcher finds

... the mechanism for how p53 loses its function in cancer cells," said Liu, whose work was published in the ... Biological Chemistry . "If we understand how the cancer forms, then we can create a more useful ... Since Plk1 is overexpressed in cancers, it is a cancer therapy target." Topors can also carry out a ...

'Normal' cells far from cancer give nanosignals of trouble

... and lung cells is the first to report that cancer cells and their non-cancerous cell neighbors, ... accessible tissue, such as the cheek for lung cancer detection. The partial wave spectroscopy (PWS) ... The results are published online by the journal cancer Research . Authors of the paper include ...

GUMC discovery highlights new direction for drug discovery

... protein responsible for Ewing's sarcoma, a rare cancer found in children and young adults. In the ... constantly. "Most targeted small molecule cancer drugs inhibit the intrinsic activity of a single ... and researcher at GUMC's Lombardi Comprehensive cancer Center. The study could provide a model upon ...

Axel Ullrich named winner of 2009 Dr. Paul Janssen Award for Biomedical Research

... in Germany, whose discoveries have led to novel cancer therapies including Herceptin (trastuzumab) , is ... chosen for the development of an entirely novel cancer therapy, culminating in the production of an ... of blood vessels in tumors and slows down cancer cell growth. Years later, a small molecule ...

Colorectal cancer

... The National cancer Institute estimates that, alone in the United States, 106,100 cases of colon cancer will occur and 49,920 patients will die both from colon and rectal cancer in 2009. Beginning in glands in the bowel ...