bridge

Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance

...icine Initiative. The goal of the initiative is to bridge the gap between clinical research and application of genomics in patient care by bringing together leading clinical research institutes with advanced Affymetrix microarray technology. Karolinska Institutet will have access to a number of new microar...

Unprecedented water level rise in Somalia

...ll as electric power lines. The destruction of the bridge limits the accessibility and mobility of the population around the city, affecting daily activities such as commuting to work, school and accessing hospitals and markets. The floods affected at least 170 households. ...

Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection

...ht eventually create prion fibril strains that can bridge the infection gap between previously separate animals like humans and elk and deer, which suffer from a prion disease called chronic wasting disease. Surewicz stresses, however, prion infection between species is still rare. "Fortunately, transmissi...

Computational Method Speeds Mapping of Cell Signaling Networks

...naling networks at once. This new work should help bridge that gap. Human T-cells--the system Nolan and Lauffenburger's team used to validate their technique--rely on a complex signaling network to protect the body from pathogens such as viruses. When a T-cell encounters a foreign invader, it relays a dang...

New World founders small in number

...cendants of archaic humans crossed the Bering land bridge from Siberia to North America. Several lines of evidence support this model, but that's where the consensus ends and the details are hotly debated. In a paper published in the premier open-access journal PLoS Biology, Jody Hey now reveals how the siz...

Pair of cancer genes found to drive both cell migration and division

...esearchers also hope their findings will provide a bridge between two scientific fields that have traditionally kept to themselves. "Scientists studying cell migration have focused on the front of the cell and what drives it, while cell division researchers have concentrated on the furrow within the dividi...

Critical step traced in anthrax infection

...est the potency of the anthrax toxin. "We tried to bridge reductionist science with the in vivo situation ?we have to do both to make correlations," he said. The researchers, who were funded by the National Institutes of Health and the National Science Foundation, will continue to study protein unfolding i...

By creating molecular bridge, scientists change function of a protein

...functions," Zhao said. "Our approach is to build a bridge between the existing protein function to the target new function by adding some intermediate functions followed by stepwise directed evolution of these intermediate functions. If done, it gives you the ability to create protein functions for any purp...

Wild grasses and man-made wheats advance research capabilities

...type of greenbug or rust in wheat may require some bridge building. Dr. Jackie Rudd, associate professor at...-made hexaploid wheats, provides a more accessible bridge to the wild species, he said. Most synthetic hexaploid wheats are crosses between Durum (pasta-type...

Wild Gorillas Handy with a Stick

...n front of her, and, walking upright, used it as a bridge to cross the muck. That tool use was seen in lowland gorillas and not mountain gorillas—the most intensively studied gorillas—may reflect the different ecological challenges facing the two populations, supporting the notion that ecology influences t...

Implantable pumps extend lives of patients too sick for transplant

...ot of data on the device when it was being used as bridge to transplantation," he continued. "We knew it could go for extended periods without problems, and that was the most compelling argument to use for implanting the device in patients who have no other options." For the trial, researchers enrolled 55 ...

Sahara's edge studied from ground, air and space to improve water management

...p a technical, human and institutional capacity to bridge Africa's water information gap using satellite data. ESA launched TIGER in 2002, as a response to that year's World Summit on Sustainable Development (WSSD) in Johannesburg, which stressed the potential of space-based systems to help achieve sustai...

Researchers make long DNA 'wires' for future medical and electronic devices

... of DNA solution," Guan said. Computer chips that bridge the gap between the electronic and the biological could make detection of certain chemicals easier, and speed disease diagnosis. But first, researchers must develop technologies to mass produce DNA circuits as they produce chip circuits today. The t...

New methods offer insight into regulatory DNA

...ual people and individual disease. The HapMap is a bridge from sequence data to the differences in individuals." The project focused on three regions of the human genome. The first, called the ENCODE regions, and about 30 million base-pairs of DNA, are being intensively studied around the world as a group...

Ancient humans brought bottle gourds to the Americas from Asia

...Asia in boats or who walked across an ancient land bridge between the continents, or that the gourds floated across the Bering Strait after being transported by humans from their native Africa to far northeastern Asia. "This finding paints a new picture of the founding of the Americas," says co-author Bruc...

New maps reveal true extent of human footprint on Earth

..." says Jonathan Foley, director of SAGE. To help bridge that gap, SAGE researchers are working towards a new "Earth Collaboratory," an unprecedented Internet-based data bank that would simultaneously draw on the knowledge of global scientists, local environmentalists and everyday citizens. Adds Foley: "[T...

Front-line immune cells mature in four stages, study shows

...is a stem-cell marker, so that told us there was a bridge between stem cells and NK cells." Once we discovered where to look (in lymph tissue), it was just a matter of careful, diligent work." The researchers also isolated cells of each stage and showed that under the proper conditions, stage-1 progenitor...

Cincinnati surgeons report new treatment for often-fatal injury

.... Giglia explains, but they are too short to fully bridge the damaged area in the chest. "Used alone, extender cuffs are hard to align and often slip into the defect to cause further complications," says Dr. Giglia. "Using a fixed stent provides an easy-to-see 'scaffolding' that can guide the surgeon to m...

Ancient global warming drove early primates' dispersal

...North America and traveled across a temporary land bridge connecting Siberia and Alaska. A third hypothesis is that primates had their origins in Africa or Asia and traveled through North America to reach western Europe. Finally, it has been suggested that the group originated in Asia and fanned out eastwar...

How plants avoid feeling the burn

... fast the electrons traveled across the carotenoid bridge between the electrodes. By measuring carotenoids of different chemical lengths, the team showed that the travel rate was fast enough to match or exceed measurements performed in the plant system. One of the greatest challenges of the experiment came...

Spinal cord bridge bypasses injury to restore mobility

...esearchers hoped to reconnect the other end of the bridge to the spinal cord, but also prevent further scarr...imately 20 percent of the nerve fibers leaving the bridge and reconnecting with the spinal cord. It brought about markedly improved mobility for the seven rat...

Smooth sailing: 'cruise ship virus' tackled by UH, Baylor College of Medicine

...or Norwalk," Ruchhoeft said. "By having the virus bridge the cube to the surface, you don't need to go through complex sample preparation steps, like extracting DNA, amplifying it and so forth. You could envision making a system work at a doctor's office or at an entry point to the cruise ship." The e...

UBC researchers find stroke death channel

...s. Junctions are composed of two hemichannels that bridge the intercellular space. Until now, scientists believed the disruption to occur at the site of glutamate channels. Glutamate is one of the brain's most abundant chemical messengers. However, therapeutic strategies targeted at glutamate channels fail...

Epstein-Barr virus might kick-start multiple sclerosis

... summer to complete her medical degree, could help bridge the gap between the research worlds of infectious diseases and autoimmune diseases. "It's an exciting new field to which Nancy could greatly contribute," he said. Whatever the ultimate cause of MS, Edwards finds the therapeutic implications of her w...

Striking the right balance between excitation and inhibition

... group of spinal cord "interneurons," neurons that bridge communications between other neurons. Many interneurons emerging in the dorsal part of the spinal cord arise from a common progenitor cell. Since mature neurons can be either excitatory or inhibitory, the researchers asked how a single parental prog...

Handling HPV vaccines and screening: The views of 100 authors

...ive (launched by the World Health Organization) to bridge the digital divide in health information access ( http://www.who.int/hinari/en/ ). ...

Singing for survival

...ong ape species, especially gibbons who in a sense bridge the evolutionary gap between great apes and monkeys, could shed light on when this ability developed in the primate lineage." ...

Caterpillars tell us how bacteria cause disease

...e. This will allow us to rapidly and inexpensively bridge the enormous knowledge gap that has grown in the post-genomic era where it has become possible to sequence a whole bacterial genome without necessarily knowing the biological function of individual genes," Dr Waterfield said. His study focuses on ...

Fighting like a girl or boy determined by gene in fruit flies

... generally, he said, such studies form a potential bridge between systems neuroscience studies of behavior and modern molecular neuroscience research into individual neurons and synapses. ...

New HIV statistics indicate increasing toll of AIDS on African American community

...health workers is a proven, effective and critical bridge between physicians and patients where mistrust of the health care system exists. Stabilize communities by increasing affordable housing. ?The scarcity of affordable housing faced by many African-Americans is at the center of a web of interconnec...

Tearing down the fungal cell wall

...ein encoded by this gene could serve as a physical bridge in the layers of the cell wall or function as a regulator of cell wall biosynthesis. Future work will focus on identifying the role of the product of the AbNPS2 gene which should allow us to get an important handle on the precise series of molecular ...

Research project tackles 'regeneration' gap

... provide fellowships for young scientists who will bridge the gaps between the different labs and investigators involved in regeneration research. "The fellows will be the glue that holds this broad group of scientists together," said Steindler, a professor of neuroscience at the UF College of Medicine....

Widely used iron nanoparticles exhibit toxic effects on neuronal cells

...eriments, using nanoparticles-laden nerve cells to bridge regions of damaged neurons. However, when they added nerve growth factor to nanoparticle-laden cells in culture flasks, they observed toxic dose-dependent effects: some cells died, and many of the survivors exhibited a diminished ability to produce n...

'Terror bird' arrived in North America before land bridge, study finds

...orth America from South America long before a land bridge connected the two continents. UF paleontologist B...nis immigrated to Texas across the Panamanian land bridge that formed about 3 million years ago connecting North and South America," said MacFadden, a curator...

Racing neurons control whether we stop or go

...he race." The findings are some of the first to bridge cognitive research and neurophysiology—making the connection between the mind and the brain. "For years, one group of researchers was looking at what neurons are doing, and a different group of researchers was looking at what people are doing," Pa...

Mimicking how the brain recognizes street scenes

...ool. This center helps MIT students and professors bridge the gap between an intriguing idea or technology and a commercially viable concept. Recognizing Scenes The IEEE paper describes how the team "showed" the model randomly selected images so that it could "learn" to identify commonly occurring f...

A 'traffic light' for neurons means 'go' for improving brain research

...h as movement instructions, could allow doctors to bridge blockages in damaged spinal columns, perhaps restoring some function to the limbs of paralyzed patients. Finally, the technique could be useful in teasing out the largely unknown functioning of healthy brains. "One day we'd like to be able to u...

Researchers examine carbon capture and storage to combat global warming

...oxide] sequestration, on the other hand, is only a bridge technology,'' he added. ''Maybe we have another hundred years of using fossil fuels, and then we'll be on to better and smarter things, one hopes. If we're going to be creating greenhouse gases for another hundred years, it's a huge problem right now...

In mice, drug protects against diabetes and atherosclerosis

...r-institutional and inter-disciplinary science, to bridge discovery with application and fruitful industry-academia collaboration."...