Enzyme involved in inflammatory bowel disease discovered at Penn State College of Medicine
... colitis and Crohn's disease in particular," bond said. She discovered meprin more than 25 years ... collaborations based upon trust and respect," bond said. Before this international effort, she ... mouse model of IBD and in humans with active IBD. bond explained, "The defect in the human meprin gene ...Weizmann Institute scientists develop a unique approach for splitting water into hydrogen and oxygen
... this work, the team demonstrated a new mode of bond generation between oxygen atoms and even defined ... generation of oxygen gas by the formation of a bond between two oxygen atoms originating from water ... remarkable considering that the generation of a bond between two oxygen atoms promoted by a man-made ...New asthma research opposes current drug treatment, says UH prof
... warnings on the combination drugs. bond and his colleagues propose an alternative to ... decreasing the flow of air to the lungs. bond has suggested, however, that although beta ... off without the beta-2 adrenoreceptor at all," bond said. "It means that whether we block receptor ...Sulfurous ping-pong in the urinary tract
... tract infections: two genes for the disulfide bond formation machinery were clustered with the gene ... decided to use ASST to study disulfide bond formation. Hence, they decided to elucidate ... ASST indeed contains an extremely short disulfide bond which can presumably only be formed by the action ...Pitt, NETL researchers report molecular chain reaction thought to be impossible
... on a gold surface. As each molecule's original bond was broken by the reaction, the molecule ... sulfur atoms. The added electron split the bond between the sulfur atoms of one molecule, ... free radical that attacked the sulfur-sulfur bond of the neighboring molecule. The radical split ...New fingerprint breakthrough by forensic scientists
... to have the opportunity to collaborate with Dr. bond and his colleagues and we look forward to some ... where prints may be left on other metals. Dr bond added: "It's certainly possible hundreds of cold ... to a practical problem in crime detection." Dr bond and Professor Rob Hillman of the Chemistry ...Simplifying manufacture of drugs, plastics earns UH chemist top honor
... compounds, such as oil, that have a single bond between carbon and hydrogen atoms. Chemists must ... this to another type known as a carbon-carbon bond to create the end product. This has involved a ... this. We are taking a carbon-hydrogen bond and converting it directly to a ...U of Minnesota researchers discover key for converting waste to electricity
... acid) into electricity, according to Daniel bond and Jeffrey Gralnick, of the University of ... it solves a fundamental biological puzzle, bond said. Scientists have known for years that ... pay the bills for a wastewater treatment plant, bond said. But more ambitious applications, such as ...Researchers describe 'implausible' chemistry that produces herbicidal compound
... what no other enzyme is known to do: break a non-activated carbon-carbon bond in a single step. Their study, appearing this week in the journal ... unusual it became. The enzyme is unusual because it breaks a carbon-carbon bond without needing anything except oxygen." The study is important ...Neuroscientists discover long-term potentiation in the olfactory bulb
... This cued her curiosity as to how a mother ewe forms such a selective bond with her lamb within several hours of parturition, a bond that is primarily dependent on olfactory sensory recognition. Using an ...Dog owners more likely to share germs with pets by not washing hands than by sleeping with dog
... the face are in good company. Surveys show that more than half of owners bond with their pets in these ways. Research done by a veterinarian at ... "I became interested in the topic because there is such a strong bond between dogs and their owners," Stenske said. "If you look at one study, ...Female plant 'communicates' rejection or acceptance of male
... level," said Bruce McClure, associate director of the Christopher S. bond Life Sciences Center and researcher in the MU Interdisciplinary Plant ... graduate student; and Christopher B. Lee, post-doctoral researcher at the bond Life Sciences Center. ...Gene associated with pair-bonding in animals has similar effects in human males
... for the hormone vasopressin appears to be associated with how human males bond with their partners, according to an international team of researchers. ... allele 334 was inversely linked to measures of the strength of a person's bond to their mate. They also report that men who carried two copies of allele ...Control switches found for immune cells that fight cancer, viral infection
... the actin network made it possible for the cells to form a tightly sealed bond with bones. "This bond is analogous to a plunger," says first author Boyd Butler, Ph.D., a ...Synthetic molecules emulate enzyme behavior for the first time
... way to initiate a change in shape. The change propagates to a key chemical bond in the middle of the molecule. That bond swings like a hinge, to initiate a twist in one particular direction that ...November GEOLOGY and GSA TODAY Media Highlights
... this is? "Conceptual uncertainty" in geoscience interpretation C.E. bond et al., Department of Geographical and Earth Sciences, University of ... This is the question addressed in the November 2007 GSA Today by Clare bond and Zoe Shipton of Glasgow University and colleagues Alan Gibbs and Serena ...New paper examines dams' effects on California salmon
... Cruz, Calif. The paper has become topical thanks to a recent $9 billion bond proposal by California Gov. Arnold Schwarzenegger to construct two new ... associated with frequent droughts in the region. Some money from the bond would be used to pay for conservation improvements such as increased ...Facile synthesis of nanoparticles with multiple functions advanced in Singapore
... water to an organic medium by mixing a solution of metal salts dissolved in water with an ethanol solution of dodecylamine (DDA). The metals would bond with the DDA and can then be extracted with an organic solvent, chemical compounds that usually have a low boiling point, evaporate easily or can be ...New advance in revolutionary 'bullet fingerprinting' technique
... of the fingerprint image, there are also indications that it could be used after other techniques have failed, perhaps as a last resort." Dr John bond said: "I am delighted that this research in the Chemistry Department is producing really interesting and useful results. This is an important area ...Scientists track chemical changes in cells as they endure extreme conditions
... such as spikes in levels of free radicals and organic acids. Specifically, the infrared microscope tracks the instantaneous response of hydrogen bond structures in cellular water as their immediate surroundings change. The spectral measurements indicate changes in hydrogen bonds, which in turn ...Computers aid in cracking deception in plants
... the pace of discovery on resistance to this pathogen," said Korkin, who also is a member of the IPG and an investigator in the Christopher S. bond Life Sciences Center. He will be applying similar computational methods in studies of Shigella flexneri, a bacterium that can cause diarrhea in ...Equity concerns raised by congestion pricing can be addressed to make approach viable
... in taxes to fund transportation, although some proportion of the group may pay more. For example, one analysis found that if a road construction bond was paid off with toll revenues rather than sales taxes, people in the lowest-income group would pay less overall, while some in the group (those who ...Understanding plants' overactive immune system will help MU researchers build better crops
... system provides plants with strong protection from pathogens," said Walter Gassmann, associate professor of plant sciences in the MU Christopher S. bond Life Sciences Center and the College of Agriculture, Food and Natural Resources. "However, this response has the potential to be highly deleterious ...Breaking the ties that bind: New hope for biomass fuels
... network of hydrogen bonds holding it together, the material also displays significant amounts of disorder, creating a different type of hydrogen bond network at certain surfaces. These differences make the molecule potentially vulnerable to an attack by cellulase enzymes. Moreover, in this ...Covering the bases: Quantum effect may hold promise for low-cost DNA sequencing, sensor applications
... was." Although quantum tunneling seems exotic, Lindsay points out that the routine leaking of electrons from one atom to another to form a chemical bond is a similar process. If significant challenges to reading single molecules through such a technique can be overcome, the method holds the ...Shellfish and inkjet printers may hold key to faster healing from surgeries
... greater control over the placement of the adhesive. This helps ensure that the tissues are joined together in just the right spot, forming a better bond that leads to improved healing and less scarring." This increased control would be a boon for surgery that relies on extreme precision, such as eye ...Microscope reveals how bacteria 'breathe' toxic metals
... the first evidence that Shewanella maneuvers proteins within the bacterial cell into its outer membrane to contact metal directly. The proteins then bond with metal oxides, which the bacteria utilize the same way we do oxygen. The process is called respiration, and it's how living organisms make ...Twin nanoparticle shown effective at targeting, killing breast cancer cells
... an associate professor at Lanzhou University in China, contributed to the paper. In a neat twist, the Brown-led team used a pH-sensitive covalent bond to connect the gold nanoparticle with the cisplatin to ensure that the drug was not released into the body but remained attached to the nanoparticle ...'Green' plastics could help reduce carbon footprint
... place in the plant to produce PHBV," said Mooney, who is also associate director of the Charles Gehrke Proteomics Center in the MU Christopher S. bond Life Sciences Center. "We also confirmed that a stable, functional complex is formed." These recent advances potentially remove two of the ...Simplicity is crucial to design optimization at nanoscale
... of two bundled proteins, and double stacks of two bundled proteins. Their molecular models replicate realistic molecular behavior, including hydrogen bond formation in the coiled spring-like alpha-helical proteins. "The traditional way of designing materials is to consider properties at the macro ...Researchers disprove 15-year-old theory about the nervous system
... sclerosis and Charcot-Marie-Tooth disorders. "Speed is the key to the nervous system," said Michael Garcia, investigator in the Christopher S. bond Life Sciences Center and assistant professor of biological sciences in the MU College of Arts and Science. "The peripheral nervous system 'talks' to ...Soybean database will help breeders engineer better-performing plants
... proteins and metabolites on or off or up or down in response to environmental cues," said Nguyen, who also is an investigator in the Christopher S. bond Life Sciences Center. "For example, a soybean plant grown under drought conditions will send out a deeper root or increase root branching. These ...Eight ASU faculty elected as AAAS Fellows
... "distinguished contributions to diffraction physics, especially atomic-resolution electron microscopy, electron diffraction studies of the chemical bond and diffractive (lens-less) x-ray imaging." Spence undertakes experiments in condensed matter physics based around the use of electron beams for ...Tool helps identify gene function in soybeans
... meaning it has extra copies of most genes," said IPG member Gary Stacey, lead author of the report and an investigator in the MU Christopher S. bond Life Sciences Center. "Nevertheless, we were able to create a number of plant variants containing different mutations and to identify a specific gene ...2 new compounds show promise for eliminating breast cancer tumors
... said. Both compounds disrupt the bonding process that one STAT3 molecule goes through to connect with another in the body. If the STAT3 can't bond to stay abnormally-active, cancer cells can't develop. The network of blood vessels that formed to feed the cancer cells also shuts off. Left ...Two new compounds show promise for eliminating breast cancer tumors
... said. Both compounds disrupt the bonding process that one STAT3 molecule goes through to connect with another in the body. If the STAT3 can't bond to stay abnormally-active, cancer cells can't develop. The network of blood vessels that formed to feed the cancer cells also shuts off. Left ...