Bipolar in Biological News

New light on bipolar treatment drugs

... years as one of the most effective treatments for bipolar mood disorder. However, scientists have never ... variant of IMPase, has previously been linked to bipolar mood disorder. This new result suggests that ... say definitively how Lithium can help stabilise bipolar disorder. However, our research does suggest a ...

USC researchers head global effort to study genetic risks that contribute to psychiatric diseases

... to study the genetic risks for schizophrenia and bipolar disorder. The USC Center for Genomic ... the disorder. They will study 5,000 patients with bipolar disorder as part of a coordinated effort led by ... to collect an additional 19,000 patients with bipolar disorder. The cohort will be the largest ...

Bipolar disorder genes, pathways identified by Indiana University neuroscientists

... map of genes likely to be involved in bipolar disorder, according to research published online ... international gene hunting studies for bipolar disorder with information from their own studies ... and created a comprehensive biological model of bipolar disorder. "Based on our work, we now project ...

NARSAD announces 2008 Prizes for Outstanding Achievement in Research on Mental Health Disorders

... whose research in the areas of schizophrenia, bipolar disorder and depression, childhood disorders and ... symptomatic and biological characterization of bipolar disorder, as well as the effectiveness of ... anxiety disorders, including PTSD and OCD, bipolar disorder, schizophrenia, childhood mental ...

Healthy Minds Across America features 48 public forums on mental health research, Sept. 14

... and progression of such illnesses as depression, bipolar disorder, anxiety, schizophrenia and autism, and ... The role genes play in risk for depression, bipolar disorder and schizophrenia, and what we're ... treatments for schizophrenia, depression and bipolar disorder; Improving pharmaceutical treatments: ...

Largest study of its kind implicates gene abnormalities in bipolar disorder

... largest genetic analysis of its kind to date for bipolar disorder has implicated machinery involved in the ... be targets of drugs used to clinically to treat bipolar disorder is astonishing." Although it's not ... the results point to the possibility that bipolar disorder might stem, at least in part, from ...

At Boston symposium, NARSAD researchers report on genes and family traits

... psychiatric illnesses, such as schizophrenia, bipolar disorder and depression. Presented at NARSAD's ... susceptibility to and pathology of schizophrenia, bipolar disorder and depression, some of the most severe, ... Traits Provide Clues to Genes for Schizophrenia, bipolar Disorder It is also important to identify the ...

New studies on schizophrenia, depression, trauma and autism highlight annual meeting

... impact on areas of the brain that contribute to bipolar disorder or schizophrenia in youth, according to ... found size difference in the brains of youth with bipolar disorder and schizophrenia, which could help ... and Regular Routines May Improve Outcomes in bipolar ...

A unique arrangement for egg cell division

... up with the correct number of chromosomes is a bipolar spindle consisting of protein filaments, called ... the microtubules originate. They predetermine the bipolar structure of the spindle that is essential to ... understand how mammalian oocytes could assemble a bipolar spindle without such centrosomes. Tracking ...

Research supports toxoplasmosis link to schizophrenia

... parasite may trigger the development of schizophrenia and other bipolar disorders. The team from the University of Leeds' Faculty of Biological ... which focuses on mental health conditions and has a particular emphasis on bipolar illnesses. Dr McConkey says: "It's highly unlikely that we will find ...

Risks and benefits of antipsychotics in children and adolescents

... of conditions such as severe conduct disorders, Tourette syndrome, bipolar disorder and schizophrenia in children and adolescents. Treatment ... of psychotic disorders in children and adolescents (schizophrenia, bipolar disorders), as well as conduct disorders, Tourette syndrome, and tics ...

NARSAD presents 2007 prizes for outstanding achievement in neuroscience and psychiatric research

... contributions to the understanding and treatment of schizophrenia, bipolar disorder, depression, autism, obsessive compulsive disorder (OCD), ... and prediction of pharmacological treatment response in unipolar and bipolar affective disorders using brain imaging with PET. She then utilized this ...

20th ECNP Congress 2007, Oct. 13-17, Vienna, Austria

... In addition, cutting edge research findings in the fields of Depression, bipolar Affective Disorders, Schizophrenia, Anxiety Disorders, Obsessive ... track the Report of the ECNP Consensus Meeting 2007 on the topic bipolar depression. With annual consensus meetings on specific topics ECNP aims to ...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

... update sessions at the ECNP Congress will deal with the current knowledge on GABA and biomarkers in neuropsychopharmacology, treatment of insomnia, bipolar disorders and schizophrenia, as well as the new classification systems ICD-11 and DSM-V. Three poster sessions with in total more than 900 poster ...

22nd Congress of the European College of Neuropsychopharmacology

... update sessions at the congress will deal with the current knowledge on GABA and biomarkers in neuropsychopharmacology, treatment of insomnia, bipolar disorders and schizophrenia, and the new classification systems ICD-11 and DSM-V. ...

Lithium may help radiation target cancer, spare healthy tissue

... Vanderbilt-Ingram Cancer Center investigators have uncovered a mechanism that helps explain how lithium, a drug widely used to treat bipolar mood disorder, also protects the brain from damage that occurs during radiation treatments. In the May 1 issue of the Journal of Clinical ...

Chantix side effects no worse with depression history

... serious psychiatric event involving suicidal thoughts and requiring hospitalization. It was in a person who had a previously undisclosed history of bipolar disorder. ...

Rethinking the genetic theory of inheritance

... twin, the different susceptibility of males (e.g. to autism) and females (e.g. to lupus), significant fluctuations in the course of a disease (e.g. bipolar disorder, inflammatory bowel disease, multiple sclerosis), among numerous others. "Traditionally, it has been assumed that only the DNA sequence ...

MU researcher identifies possible genetic causes of borderline personality disorder

... COLUMBIA, Mo. According to the National Institute of Mental Health, borderline personality disorder (BPD) is more common than schizophrenia or bipolar disorder and is estimated to affect 2 percent of the population. In a new study, a University of Missouri researcher and Dutch team of research ...

Ultrasound shown to exert remote control of brain circuits

... Stimulation (DBS) and Vagal Nerve Stimulation (VNS) have been shown to be effective in the management of psychiatric disorders such as depression, bipolar disorders, post-traumatic stress disorder, and drug addition, as well as for therapies of neurological diseases such as Parkinson's disease, ...

Brain-nourishing molecule may predict schizophrenia relapse

... drug is becoming less effective and a relapse is imminent, the researchers say. Decreased BDNF levels already have been associated with relapsing bipolar disease and depression, Dr. Buckley says. Dr. Pillai and others have shown that the BDNF levels in patients with schizophrenia are generally lower ...

Study provides insight on a common heart rhythm disorder

... with electrical activity," he added. "In addition to heart disease, ankyrins could be involved in other 'excitable' cell diseases such as epilepsy, bipolar disease and diabetes." ...

Eli and Edythe L. Broad make unprecedented gift to endow Broad Institute of Harvard & MIT

... to common human diseases; Identifying scores of new genetic risk factors for diseases such as type 2 diabetes, Crohn's disease, schizophrenia, bipolar disorder, autism, cardiovascular disease, and a variety of cancers; Classifying human cancers by their genomic alterations, rather than by their ...

Study finds connections between genetics, brain activity and preference

... that has been implicated in animal studies of the brain's reward/aversion function. Study lead author Roy Perlis, MD, medical director of the MGH bipolar Program, and colleagues previously found that depressed men with a particular variation near the gene coding for CREB report greater difficulty ...

Scientists learn how food affects the brain

... in humans has been associated with increased risk of several mental disorders, including attention-deficit disorder, dyslexia, dementia, depression, bipolar disorder and schizophrenia," he said. "A deficiency of omega-3 fatty acids in rodents results in impaired learning and memory." Children who ...

Epigenetic changes discovered in major psychosis

... have discovered epigenetic changes (i.e. chemical changes to a gene that do not alter the DNA sequence) in individuals with schizophrenia and bipolar disorder. This is the first epigenome-wide investigation in psychiatric research, and this groundbreaking data may be a significant step on the ...

Advertisers, neuroscientists trace source of emotions in brain

... they found the fMRI data and response converged on two of three measures pleasure-displeasure and excitement-calm. Under the AdSAM system, these bipolar dimensions as well as a third, dominance-submissiveness form the foundation for more specific emotions. Where the researchers compared the AdSAM ...

Duke scientists map imprinted genes in human genome

... 8, where none had been found before. One of them, KCNK9, is mostly active in the brain, is known to cause cancer, and may also be linked to bipolar disorder and epilepsy. The second, DLGAP2, is a possible bladder cancer tumor suppressor gene. Hartemink says experiments to confirm that all ...

Team of scientists develops non-invasive method to track nerve-cell development in live human brain

... brain, which can be a sign of cancer. In other patients, it could show us how neurogenesis is related to the course of diseases such as depression, bipolar disorder, Alzheimers, Parkinsons, MS, and post-traumatic stress disorder. In 2006, Dr. Enikolopov demonstrated that the antidepressant fluoxetine ...

Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms

... PhD, are currently published online in the Journal of Biological Chemistry. Lithium has been used to treat mood affective disorders, including bipolar disease for decades. While the drug has been shown to protect neurons, the underlying mechanism of its therapeutic action is not understood. In ...

Mental disorders are disorders of the brain

... such as depression, specific phobias, somatoform disorders, alcohol- and drug dependence, social phobia, generalized anxiety disorder (GAD), bipolar disorder, psychotic disorders, obsessive compulsive disorder (OCD) or eating disorders. The estimated total number of affected is 82,7 million in ...

Brain holds clues to bipolar disorder

... clues to understanding, diagnosing and treating bipolar disorder, according to findings being presented today at the Seventh International Conference on bipolar Disorder. Two studies, featured in a press ... Institute of Mental Health (NIMH), suggests that bipolar disorder arises from abnormalities in neuronal ...

Genetic roots of bipolar disorder revealed by first genome-wide study of illness

... The likelihood of developing bipolar disorder depends in part on the combined, small ... in human genes to find those associated with bipolar disorder. Results were published online May 8 in ... in their search for better medications for bipolar disorder," said NIH Director Elias A. Zerhouni, ...

Lithium builds gray matter in bipolar brains, UCLA study shows

... that lithium, long the standard treatment for bipolar disorder, increases the amount of gray matter in ... surface of the brain in people diagnosed with bipolar disorder. When the researchers compared the brains of bipolar patients on lithium with those of people without ...

Brain networks strengthened by closing ion channels

... and for cognitive changes in schizophrenia, bipolar disorder, or attention deficit hyperactivity ... disrupted in disorders such as schizophrenia and bipolar disorder. The current study found that brain ... severe mental illnesses like schizophrenia and bipolar disorder, which can involve mutations of a ...

New gene linked to bipolar disorder

... A new gene linked to both depression and bipolar disorder has been identified by UCL (University ... Mors at the University of Aarhus, first looked at bipolar cases in families living in the UK and in ... then at large numbers of unrelated people with bipolar disorder. The results of the genetic searches, ...

Studies look at how genes affect antipsychotic drug response

... treat mental illnesses such as schizophrenia and bipolar disorder. Jeffrey Bishop, assistant professor ... in children ages 8-18 who suffer from pediatric bipolar disorder. An increase in prolactin (a pituitary ... Risperidone is widely prescribed to treat bipolar disorder in children, accounting for half of all ...

Brain's 'gambling circuitry' identified

... in disorders including gambling addiction, bipolar disorders, and schizophrenia. In their ... as well as a variety of mental illnesses such as bipolar disorder and schizophrenia, are partially ... planning, and choice. "For example, a bipolar subject during a manic episode may invest in a ...

Beyond lithium for bipolar disorder

... for many of the two million Americans with bipolar disorder, it is not without its downside. People ... and gain weight. However, better treatments for bipolar disorder depend on a better understanding of the ... "suggest new directions toward the treatment of bipolar disorder." The behavior of one such activated ...