A gene's first 'kiss' sets off that affair known as puberty
...king with Dr. Plant and now with the department of biological sciences at Quaidi-i-Azam University in Islamabad, Pakistan; Claudio Mastronardi, Ph.D., and Sergio R. Ojeda, D.V.M., both from the division of neuroscience at the Oregon National Primate Research Center; and Stephanie B. Seminara, M.D., and William ...UCSB scientists probe sea floor venting to gain understanding of early life on Earth
...essor of geology. Newly discovered geological and biological manifestations of hydrothermal activity at two sit...The team describes newly discovered geological and biological manifestations of hydrothermal activity at two sites on young abyssal hills flanking the East Pacifi...UAB scientists discover the origin of a mysterious physical force
...statically charged molecules, such as DNA and some biological compounds, and when thin films form in detergents....s the solvent in which most physical, chemical and biological processes take place. Therefore, it is essential to understand the nature of interactions between mo...Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
...nt markers and their small size make them idealfor biological imaging. The researchers then added the molecules togerminated lily pollen grains and examined them under a confocalmicroscope.This is the very first time that Quantum Dots have been utilized forlive imaging in plant systems. The study opens the door...New, automated tool successfully classifies and relates proteins in unprecedented way
...proteins within cells," saidMurphy, a professor of biological sciences, machine learning, andbiomedical engineer...rvik and PeterBerget, both associate professors of biological sciences at CarnegieMellon. The computational analyses were carried out together with XiangChen, a g...UW's Rosetta software to unlock secrets of many human proteins
...oteins fold, informationthat is highly valuable to biological and biomedical researchers.UW Tech Transfer's Digital Ventures licensed Rosetta software withoutcharge to the Institute for Systems Biology (ISB), a non-profitresearch organization. The institute has partnered with IBM and UnitedDevices, an Austin-ba...Researchers find how protein allows insects to detect and respond to pheromones
...oteins fold, informationthat is highly valuable to biological and biomedical researchers.UW Tech Transfer's Digital Ventures licensed Rosetta software withoutcharge to the Institute for Systems Biology (ISB), a non-profitresearch organization. The institute has partnered with IBM and UnitedDevices, an Austin-ba...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
...all labs were the next mostcommon contributor, and biological differences in different sampleswere the largest source of variation.“This study indicates that microarrays have a high degree ofreproducibility, as long as standardized protocols are carefullyfollowed,?said Jacobson. These promising results will all...Inexpensive, mass-produced genes core of synthetic biology advances at UH
... issue of Nature, the weeklyscientific journal for biological and physical sciences research. “Synthetic genes are like a box ofLego building blocks,?Gao said. “Their organization is very complex,even in simple organisms. By making programmed synthesis of geneseconomical, we can provide more efficient tools to...Study finds more than one-third of human genome regulated by RNA
...iny,single-stranded pieces of RNA are newcomers to biological research. Itwasn't until 2000 that researchers even knew that microRNAs existed inhumans. Now, in the January 14 edition of the journal Cell, BenjaminLewis, a graduate student working jointly with Whitehead's Bartel andMIT associate professor of biol...NYU researchers simulate molecular biological clock
...iny,single-stranded pieces of RNA are newcomers to biological research. Itwasn't until 2000 that researchers even knew that microRNAs existed inhumans. Now, in the January 14 edition of the journal Cell, BenjaminLewis, a graduate student working jointly with Whitehead's Bartel andMIT associate professor of biol...Automatic extraction of gene/protein biological functions from biomedical text
...eveloped a method for automatically extracting the biological process functions of genes/protein/families based on Gene Ontology (GO) from text using a shallow parser and sentence structure analysis techniques. When the gene/protein/family names and their functions are described in ACTOR (doer of action) and OB...New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
...said Brian Ross, Ph.D., professor of radiology and biological chemistry at the U-M Medical School and a member of the U-M Comprehensive Cancer Center. In the study, 20 participants with brain tumors underwent diffusion MRI before beginning a new treatment involving chemotherapy, radiation therapy or a combinat...Solution to Pollution: New Bacteria Eats Toxic Waste
...capability to be a master engineer,?said Ron Sims, biological and irrigation engineering department head. “Past disposal practices and accidental spills have put these carcinogens in our environment, and nature has figured out a way to cleanse herself. We want to be able to understand it better through genomic ...Scientists collaborate to assess health of global environment
... oversee major international treaties dealing with biological systems requested the information. The lack of adequate data to uphold such treaties is what helped convince the United Nations to initiate the program, he added. Case studies In September, the assessment team will release five technical reports to...Taking Aim With Nanoparticle PEBBLEs
...chool of Public Health; Brian Ross, a professor of biological chemistry and of radiology in the Medical School; Alnawaz Rehemtulla, an associate professor of environmental health sciences, radiation oncology and radiology with joint appointments in the Medical School and the School of Public Health; and Yong-Eu...Probing The Promise And Perils Of Nanoparticles
...meable. Hong is now trying to learn more about the biological mechanisms involved. The usual explanation for how polycationic polymers and similar nanoparticles get into cells involves a process called polycation-mediated endocytosis. But Hong's experiments suggest that nanoscale hole formation may be at least ...Nanogen Issued Patent for Electronic Microarray With Memory
...tage information allows for precise control of the biological molecules during analysis and increases data management efficiency by tracking test site activation and array usage directly on the electronic microarray cartridge. "This addition to our growing intellectual property portfolio illustrates our abilit...Study shows nanoshells ideal as chemical nanosensors
...nts of amaterial, like a few molecules of a deadly biological or chemicalagent....Scientists identify genetic pathways essential to RNA interference
...iana, both of which are common model organisms for biological research. The process interrupts the usual transfer of instructions from double-stranded DNA, through single-stranded messenger RNA and finally into proteins. Short, double-stranded pieces of RNA bind to the complementary messenger RNA segments, shut...Ants Genetic Engineering Leads To Species Interdependency
...e to a system of interdependence at ahigh level of biological organization - in this case, the production ofworker ants for both species. Millionsof years before the first modern humans evolved, ants were practicingmany of the social innovations we consider to be our own: division oflabor, agriculture, and eve......l contributions to structural studies of important biological molecules through X-ray analysis; to our understanding of protein synthesis; to the deciphering of the genetic code by which hereditary information is stored and transcribed in the cell; and to our conception of the human brain. Francis Harry Compto...Development of portable infectious disease detector
...seases, including HIV-AIDS and measles, as well as biological agentssuch as ricin and anthrax, is the object of a new jointuniversity/industry research project.Vanderbilt University's Institute for Integrative Biosystems Researchand Education (VIIBRE) and Pria Diagnostics LLC, a privately heldCalifornia company...Alcohol's effects on gene expression in the central nervous system
...ex, and ventral tegmental areas show that distinct biological pathways are associated with alcohol's action in s...hat alcohol produces multiple effects on different biological processes," said McBride, "and that these changes are different in several brain regions which may b...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...videdata in a way that is meaningful and useful to biological researchers."Moleculizer was developed in the context of MSI's "Alpha Project", anambitious experimental and computational effort to understand thequantitative behavior of a cell signaling pathway in yeast. The AlphaProject is funded by the National ...Nano-Probes Allow an Inside Look at Cell Nuclei
...alifornia-based Quantum Dot Corporation for use in biological assays. More recently, Chen and Gerion wondered i...ntum dot. The result is a hybrid quantum dot, part biological molecule and part nano-sized semiconductor, that is small enough to slide through the nuclear membra...The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
...w.rcsb.org/pdb/, a repository of three-dimensional biological structure data. “The protein structures solved by the PSI are more than a scientific stamp collection,?explained Norvell. “They will help researchers better understand the function of proteins, predict the shape of unknown proteins, quickly identify...The BIOS Initiative - open source biotechnology is born
...et), an online collaborative research platform for biological innovation, developed in partnership with CollabNe...ute use of intellectual property, informatics, new biological sciences, and the unique human element that Internet communication now provides" says Jefferson. ...Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells
...that the actual dose of BPA exposuremay change the biological response,?Dr. Knudsen said.The safety of BPA has been under intense debate for several years, withsome arguing that exposure to the chemical among humans is safe, withothers contending that it may promote the growth of human tumor cellsand alter the ...PANTHER Protein Classification System Database 5.0
...0. Proteins are classifiedby family, molecular and biological function (GO ontology) and knownpathways. Its main...sources for associatingprotein families with their biological pathways, as well as new toolsfor analyzing gene expression data in relation to molecular functions,...Newly Discovered Compound Blocks Known Cancer-Causing Protein
...d discovered a new chemical compound with a unique biological function. When the scientists tested the compound's ability to inhibit Ras function in living cells, they found it blocked the ability of colon cancer cells to grow independently in soft agar, a typical test of the cancerous potential of cells. "Th...New RNA polymerase discovered in plants
...rying out functions of cells and for expression of biological traits. It does its job by copying a template of DNA genetic information in order to make RNAs that encode proteins or that function directly in the cell. Biologists have studied three kinds of RNA polymerase for decades in organisms ranging from br...Agilent Technologies releases automated literature search tool for biology researchers
...ure search tool for the multidisciplinary study of biological systems. The tool is available as a free plug-in t...nables researchers to form a visual map of complex biological networks, increasing their understanding of molecular pathways and the biological causes of disease....RNA project to create language for scientists worldwide
...ntinuous discovery of new RNA molecules with novel biological functions is beginning to show that RNA plays far more roles than originally believed. For instance, while genomicists had previously determined that humans and chimpanzees share 99 percent of the same protein genes, it has now been discovered in the...X-Ray Beams And Fruit Fly 'Flight Simulator' Aid Scientists' View Of Muscle Power
...The results suggest a model for how these powerful biological motors turn “on?and “off?during the wingbeat. “Small flying insects face an enormous task ?generating enough power to overcome gravity, air resistance and drag ?and they do this by beating their wings ferociously,?said Maughan. “We found out that ti...UCSD team discovers specialized, rare heart stem cells in newborns
...en placed in the intact heart, they might serve as biological pacemakers for infants born with heart block, which could also be valuable." After the isl1+ cells were found in newborn rats, the UCSD team used sophisticated genetic methods to tag the progenitor cells in living embryonic tissue and in the newborn...Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
...ontrast," said Eric Ahrens, assistant professor of biological sciences in the Mellon College of Science at Carnegie Mellon. "Now, with our approach, we have put this job into the hands of the molecular biologist. Using off-the-shelf molecular biology tools we can now enable living cells to change their MRI cont...Affymetrix and Stratagene Announce Strategic Software Alliance
...e result will be better quality data to accelerate biological discovery and validation." "We are very pleased to announce this expansion of our longstanding relationship with Stratagene," said Steve Lincoln, Vice-President of Informatics at Affymetrix. "The combination of our GeneChip platform and the ArrayAss...VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
...ltaneously, together with large databases of other biological information, researchers were able to identify sev...genes regulated by alcohol participated in certain biological pathways, such as the one leading to the production of myelin. Myelin is a form of molecular insulat...Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
...nal that is uniquely suited for visualizing living biological systems." According to Therein, there is keen interest in developing new technology that will enable optical imaging of cancer tissue, as such technology will be less costly and more accessible than MRI-based methods and free of the harmful side eff...Wiley announces publication of Databasing the Brain
...w data obtained using different species, levels of biological organization, and methods can be integrated. "Databasing the Brain" Offers: * A solid foundation for the application of computer science in order to build databases, tools, and workflow environments in neuroscience * An analysis of neuronal...Antibiotic might fight HIV-induced neurological problems
...lly designed to cross the blood-brain barrier, the biological "wall" that limits what can pass from the blood in...r we discovered that SIV triggers some of the same biological pathways of cell death and inflammation as these other diseases," says Sheila Barber, Ph.D., assista...Supercomputer Dedicated To Bioengineering, Computational Biology Installed
...r dedicated to solving a wide range of challenging biological problems. The 210-node Dell PowerEdge Linux cluste...r. "No single computational model spans all these biological scales, but this powerful new cluster will enable us to integrate models over many of these scales, ...Effective Cancer Treatments Follow The Clock
...ice, the scientists found that the body's internal biological clock affects the survival of immune cells that are targets of the anti-cancer drug cyclophosphamide (CY). “We became interested in examining this issue because there is a long history of knowledge that chemotherapeutic agents produce different mort...LUCA technologies confirms real-time methane generation
...ates that the methane formation is the result of a biological process occurring today. Luca is actively working to characterize Geobioreactors and the microbial consortia that populate them, as well as to understand the metabolic processes by which those consortia generate methane. The company expects to evalu...Multiple Campylobacter Genomes Sequenced
...their presence could help to explain the different biological behaviors of these strains. There are also major variations in the genes responsible for synthesis of molecules that are important for the interaction of Campylobacter with the environment. Such differences could underlie the host specificity of the ...Potential treatments for neurofibromatosis
...t cell itself," said Dr. Clapp. That's because the biological activities of non-malignant cells are stable, while malignant cells are constantly changing due to the genetic instability common to tumors. By using drugs that target the mast cells' ability to promote blood vessel growth, Clapp and his colleagues ...Scientists discuss improved biopesticides for locust control in West Africa
...IRED), and Foster Agblevor, associate professor of biological systems engineering, traveled to Senegal to speak about their biopesticide research at the "International Scientific Seminar on Desert Locusts" held in Dakar in January. Biopesticides are types of pesticides derived from natural materials such as mi...Variation in women's X chromosomes may explain differences among individuals, between sexes
...s," he continued. Notwithstanding the genomic and biological significance of these sex-specific differences, many questions remain, Willard said. For example, further study is required to determine if the pattern of X inactivation differs across tissues or over time and whether there are characteristic pattern...Use of PET can reduce, may eliminate more strenuous drug development trials with animals
... a person's living biology as it tracks a range of biological processes from metabolism to receptors, gene expression and drug activity. This imaging tool examines the chemistry and biology of a person's body by monitoring ingested tracer molecules, and it is used to study the metabolism of the brain, the heart...Programmable cells: Engineer turns bacteria into living computers
...e more commonly associated with silicon chips than biological organisms. The new paper applies similar techniques to a large population of cells. "Here we're showing an integrated package where the cells have an ability to send messages and other cells have the ability to act on these messages," said Weiss. T...UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders
...itute co-director, and a professor of medicine and biological chemistry. "I see cancer and stem cells as tightly linked," Gasson said. "More and more evidence suggests that cancer is a stem cell disease. Many of our current therapies are not effective because they don't target the cancer stem cells. Our experi...DuPont's first biologically derived polymer receives global recognition
...nnovation, the first DuPont polymer derived from a biological source, has been recognized by the China State Int...he key Sorona® ingredient, from corn using a new biological process that requires over 40 percent less total energy than the traditional petrochemical feedstock...Probing the promise and perils of nanoparticles
...meable. Hong is now trying to learn more about the biological mechanisms involved. The usual explanation for how polycationic polymers and similar nanoparticles get into cells involves a process called polycation-mediated endocytosis. But Hong's experiments suggest that nanoscale hole formation may be at least ...New online portal merges vast data on Gulf of Maine ecosystem
... "This new tool will enhance our understanding of biological patterns in the Gulf of Maine, across space and time, and illuminate critical trends related to this important international resource," says Evan Richert, program director for the Gulf of Maine program. "The new portal is the door to a treasure of da...HIV vaccine trial breaks ground for future research
... For the non-white group, the authors suggest that biological differences in immune response or genetic markers of resistance to infection could have made the vaccine more effective. Also examined in the trial were the immune responses to the vaccine. The vaccine was able to generate antibody responses in virt......" -- sequences that appear in the genome but whose biological purposes were previously unknown. The method not...otation," a way of assigning the mystery sequences biological function and ranking them based on their similarity to genes known to encode proteins. Proteins are ...Flocking together: Study shows how animal groups find their way
... of the University of Bristol. In addition to its biological insights, the research may provide ideas for designing robots that work together in groups, said Couzin, who has collaborated with roboticists at Princeton on designs for fleets of underwater vehicles. "Say you had a group of robots exploring a plan...Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert
...and protein. And we were able to visually identify biological materials from a standard image captured by the ro...ely creating a "macroscopic quilt" of geologic and biological data in selected 10 by 10 centimeter panels. After the rover departed a region, the ground truth sci...Advances in the characterisation of the oyster mushroom genes
...cular perspective. Cellulose is the most abundant biological polymer on the planet. It is made up of units of D-glucose united by means of glycosidic links that form long polymer chains. The breaking down by live organisms takes place through the action of three types of enzymes: endogluconases, cellobiohydrol...