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Novel antiviral technology inhibits RSV infection in mice
...noparticle and gene silencing technologies thwarts attacks ofrespiratory syncytial virus (RSV) -- a virus associated with severebronchitis and asthma, an animal study by University of South Floridaresearchers found. The study was reported in the January 2005 issue ofthe journal Nature Medicine.RSV infects lu...Computers to be used to find blueprint for new influenza drug
... the cells in our throats that the flu virus first attacks when a person becomes infected. The flu virus would be deceived into attacking the drug, called an inhibitor, instead of the cells. The three-year project will be largely carried out by examining the behaviour of atoms of the influenza virus which a...Scientists seek answers on what activates deadly anthrax spores
...stop anthrax remains high, not only after the 2001 attacks through the mail that resulted in 18 cases and five deaths, but also after the recent scare at two military mailroom facilities when anthrax alarms went off. The group also would like to understand another closely related bacterium, Bacillus cereus,...Molecular machine may lead to new drugs to combat human diseases
...ed an intron from a bacteriophage, a molecule that attacks bacteria, to obtain an intron crystal structure trapped in the middle of the cutting and pasting cycle. As introns proceed through their work cycle, they change shape by folding and bending. By crystallizing the complex at various stages, the scienti...In the sea slug's defense against lobsters, confusion is key
...edators, but the mechanisms by which such chemical attacks actually work against their intended targets are not well understood by researchers. New work has now shown that such chemical defenses can involve modes of trickery that had not previously been appreciated as components of chemical defense. When at...Vital step in cellular migration described by UCSD medical researchers
...sorders where the body's immune system incorrectly attacks the body's own tissue." From the genesis of human life to birth and beyond, cell migration is a complex, extremely important process that is not completely understood by researchers. In order to move, a cell must be polarized so that the molecular p...Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
...rom donated stem cells will be available to launch attacks on the patient's cancer cells--the so-called "graf...r surface. The target that a T cell recognizes and attacks depends on the makeup of its receptor, which is constructed of protein building blocks. Each protein...Implanted Devices Detect High-Risk Heart Failure Patients
...rtery disease, high blood pressure, previous heart attacks and valve problems. An estimated 4.7 million Americans suffer from the condition, with 400,000 new cases reported each year. Roughly one-half of patients die within five years of diagnosis. Although there is no cure, drugs can improve the strength o...Vascular structure and function improve with diet and exercise
...r the risk of high blood pressure, diabetes, heart attacks and stroke," said presenter and lead author Kunihiko Aizawa, M.Sc., a Ph.D. candidate at the University of Western Ontario in London, Ontario, Canada. "We found that there probably are some things that happen in even eight weeks." Researchers studie...New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines
...stem destroys these types of antibodies to prevent attacks against self. The Duke study suggests HIV vaccines may have failed in part because certain proteins on HIV's protective outer coat trigger only short-lived, self-reactive antibodies instead of long-lasting, HIV-specific antibodies. The results also ...Asthma gene clusters identified
Children who suffer from acute asthma attacks share a genetic profile that appears to be unique to these children, according to a new study by researchers at Cincinnati Children's Hospital Medical Center. The discovery opens the door to the possibility of designing treatments specifically tailor...Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients
...disease. It develops when the body's immune system attacks healthy nerve cells and disrupts normal nerve signaling. Patients experience a wide range of symptoms—including tingling, paralysis, pain, fatigue, and blurred vision—that can appear independently or in combination, sporadically or persistently. Alth...Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries
...ce for blood flow and can lead to angina and heart attacks in some people. Fatty buildups occur on the inner lining of an artery and gradually thicken into a plaque. As plaque grows, it narrows the artery more and more. When the plaque ruptures, blood clots form that can block the artery entirely. Low-densi...Silence the gene, save the cell: RNA interference as promising therapy for ALS
...y. ALS is a progressive neurological disease that attacks the motor neurons controlling muscles. Although its victims retain all their mental faculties, they experience gradual paralysis and eventually lose all motor function, becoming unable to speak, swallow or breathe. Known also as Lou Gehrig's disease,...Scientists journey to southern Africa to unravel the secret world of elephant communication
...for humans, but young elephants are susceptible to attacks by lions and hyenas. When a predator appears, older members of the herd emit intense warning calls that prompt the rest of the herd to clump together for protection and then flee the scene. In 1994, O'Connell-Rodwell recorded the dramatic cries of a...Roots Engage in Underground Chemical Warfare
...n antimicrobial agents that ward off the continual attacks by soil pathogens. The work is published in the March 10 issue of the journal Nature. The exudates from Arabidopsis roots kill a wide range of bacteria, confirming that roots are not always vulnerable, anchored targets. The natural production of th...What's really making you sick? Plant pathologists offer the science behind Sick Building Syndrome
...s typically associated with SBS range from allergy attacks and asthma to more complex medical problems involving exposure to toxins. Mold is a common cause of SBS, said Mani Skaria, Ph.D, plant pathology professor and interim chair of the Department of Agronomy and Resource Sciences, Texas A&M Universit...A little stress gives beneficial oomph! to immune system
...oriasis. In autoimmune diseases, the immune system attacks the body. "Understanding mechanisms that mobilize leukocytes to potential battle stations during stress could help us figure out ways to boost the immune response when it could be most helpful to do so, such as during surgery, vaccination or infecti...Newly Discovered 'Branding' Process Helps Immune System Cells Pick Their Fights
...une conditions where the immune system erroneously attacks healthy tissues. Such disorders include rheumatoid...to our own proteins, potentially leading to T cell attacks on the self," says Unanue. Unanue and colleagues, who publish their results on May 31 in the Procee...UCLA study assesses cost-effectiveness of Hepatitis B drugs
...on serious liver infection in the world. The virus attacks liver cells and chronic hepatitis B disease can lead to liver failure, cirrhosis or cancer of the liver. About 90 percent of healthy adults who are infected with Hepatitis B recover with no problems, but 10 percent develop chronic disease. In childre...Columbia study shows widely used artery clearing device does not help patients during heart attack
...nt. The study also measured the size of the heart attacks by measuring the uptake of a tracer in the heart, and found that there was no difference for patients who received distal protection. According to Dr. Stone, not using distal protection devices will reduce the cost of angioplasties during heart atta...Disabling gene defuses rheumatoid arthritis in mice
...e thought the cells that were most active in these attacks were adaptive immune cells including T cells. Most of these cells are like guided missiles: they get a fix on a specific target, pursue it and attack it. "Classically, everyone thought that the T cells somehow recognized something specific in the jo...Shark attack worries? Driving to the beach is more deadly
...ergic reaction to eating peanuts. Despite several attacks in Florida recently - one that killed a 14-year-old girl - shark attacks remain very rare when you put it all into perspective, McEachran believes. "There are millions of p...New HIV drug candidate developed in Sweden
...ergic reaction to eating peanuts. Despite several attacks in Florida recently - one that killed a 14-year-old girl - shark attacks remain very rare when you put it all into perspective, McEachran believes. "There are millions of p......ergic reaction to eating peanuts. Despite several attacks in Florida recently - one that killed a 14-year-old girl - shark attacks remain very rare when you put it all into perspective, McEachran believes. "There are millions of p...FDA Approves New Treatment for Chronic Hepatitis B
...disease caused by the hepatitis B virus (HBV) that attacks the liver. The virus can cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure, and death. According to the Centers for Disease Control and Prevention, approximately 1.25 million Americans are chronically infected w...Stem cell treatment improves mobility after spinal cord injury
...colleagues identified how the body's immune system attacks and destroys myelin during spinal cord injury or disease states. They also have shown that when treated with antibodies to block immune system response, myelin is capable of regenerating, which ultimately restores sensory and motor activity. Oswald ...Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine
... a dye to stain those cells green. When Y. pestis attacks a cell it uses the type-III pathway -- a needle-like projection -- to inject various toxins into the cell, killing it. The researchers endowed these bacteria with an additional enzyme, which the microbes also injected in cells. This enzyme can snip t...Morphine for Chest Pain Increases Death Risk
...ed to relieve the chest pain associated with heart attacks in 1912 and has been used regularly ever since. Nitroglycerin has been used for more than 130 years for the relief of chest pain, also known as unstable angina. It works by relaxing blood vessels and allowing blood flow to increase. "Nitroglycerin h...UNC plant researchers discover proteins interact to form hair-trigger protection against invaders
...surprise while investigating how plants respond to attacks from disease organisms such as bacteria and viruses. "Contrary to what we thought we'd find, our experiments showed that at least three different proteins work in concert with one another in tug-of war or teeter totter-fashion to keep plant defenses...FDA approves more generic AIDS drugs
...surprise while investigating how plants respond to attacks from disease organisms such as bacteria and viruses. "Contrary to what we thought we'd find, our experiments showed that at least three different proteins work in concert with one another in tug-of war or teeter totter-fashion to keep plant defenses...A whole lot of shaking goin' on triggers early hatching in red-eyed tree frogs
...h vibrational differences, hatching early to snake attacks but not to rain At the edge of Ocelot Pond, Panama, red-eyed tree frog embryos still in their eggs are about to make a life-or-death decision. The egg clutch, a gelatinous blob clinging to a leaf overhanging the water, has been spied by a bright gre...Anthrax test, developed by army and CDC, receives FDA approval
...l cells grow unaffected." Well before the anthrax attacks of 2001, scientists at USAMRIID and the CDC recognized the need for an FDA accepted method for identifying B. anthracis in clinical specimens. In 2002, FDA's Division of Clinical Laboratory Devices agreed to recognize tests for B. anthracis as eligib...'Mad cow' proteins successfully detected in blood
...l cells grow unaffected." Well before the anthrax attacks of 2001, scientists at USAMRIID and the CDC recognized the need for an FDA accepted method for identifying B. anthracis in clinical specimens. In 2002, FDA's Division of Clinical Laboratory Devices agreed to recognize tests for B. anthracis as eligib...Purdue scientists may have found key to halting spinal cord damage
...r which they are gone. But the acrolein that these attacks release survives in our bodies much longer, for several days at least, and its toxicity is well documented." For example, acrolein has long been known to cause cancer when its concentration in the body rises, and not much is needed to be dangerous. ...Attacks of King George III's madness linked to key metabolism molecule
...uncovered a molecular explanation for the episodic attacks of irrational and demented behavior in porphyria, ...ained how porphyria symptoms can occur in episodic attacks triggered by fasting, and why they can be treated by feeding carbohydrates and glucose," says Spiege...Why are coyotes getting more aggressive?
... notes that in the past two decades, several dozen attacks on humans have been reported in California. Coyotes, which are closely related to dogs and wolves, are ubiquitous in North America, but they rarely have been a danger to humans. Fearful of being hunted and trapped, these large carnivores have typica...Redesigned protein accelerates blood clotting
... in excessive clotting, blocked arteries and heart attacks in otherwise healthy people. In patients with hemophilia, however, enhanced clotting is desirable." ...New Lab Research May Help Those Deafened By Immune System Attack
...n thousands of people each year, the immune system attacks the inner ear, home to the tiny, delicate structures that allow us to hear. Without warning, in days or weeks, patients lose the ability to hear in one or both ears. Some might get part or all of their hearing back if they take steroid medicines, but...Defect in gene causes 'neuralgic amyotrophy'
...em. This heritable disease causes prolonged acute attacks of pain in the shoulder or arm, followed by tempor...lgic Amyotrophy (HNA) is characterized by repeated attacks of pain in a shoulder, arm, and/or hand, followed by total or partial paralysis of the affected area...Quantum dots provide a faster, more sensitive method for detecting respiratory viral infections
... Few children in the U.S. die from RSV but it also attacks the elderly, causing some 17,000 to 18,000 deaths annually. Individuals with impaired immune systems are another highly susceptible group. Worldwide, the virus causes about one million deaths annually. Current methods of detecting the virus can take...How cell suicide protects plants from infection
...ter understanding of how plants fend off microbial attacks through carefully controlled destruction of infected cells," said James Anderson, of the Division of Genetics and Developmental Biology at the National Institute of General Medical Sciences (NIGMS). "Like other studies carried out in model organisms,...New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
...sease in which the body's immune system mistakenly attacks its own insulin-producing beta cells and eventually kills them. Early in this process, white blood cells called T lymphocytes infiltrate the islets of the pancreas (an inflammatory condition known as insulitis), causing the blood vessels to become le...Ants, not evil spirits, create devil's gardens in the Amazon rainforest, study finds
.... hirsuta saplings. "We conclude that M. schumanni attacks only non-host plants, such as C. odorata, and that it does not rely on the presence of domatia to discriminate between its host and other plant species," the Stanford team notes. Chemical analysis revealed that the only compound produced by the ant...New tooth enamel dating technique could help identify disaster victims
...as deployed in the days following the September 11 attacks in New York's World Trade Center rubble. Carbon-14, or radiocarbon, is naturally produced by cosmic ray interactions with air and is present at low levels in the atmosphere and food. Atmospheric testing of nuclear weapons from 1955 to1963 produced a...Tiny avalanche photodiodes target bioterrorism agents
After the anthrax attacks in the United States in 2001 the threat of a larger and more deadly bioterrorism attack -- perhaps from smallpox, plague or tularemia -- became very real. But the ability to detect such biological agents and rapidly contain an attack is still being d...'License to kill' enables powerful immune attack cells in mice
...nse" that allows them to unleash their most potent attacks on enemies. This licensing process apparently hel...cells in mice became much more capable of mounting attacks against invaders after they first encountered the mouse version of MHC. "The structure of these rec...Software 'agents' could help unmask reality of disease clusters
...heir transactions, and prevent 'Trojan horse'-like attacks by fake or rogue agents. "These mechanisms could include the creation of virtual institutions to insulate host organisations from agents and minimise leakage by limiting access to only the necessary data." ...Anthrax stops body from fighting back, study shows
... has increased since the Sept. 11, 2001, terrorist attacks and the anthrax attacks that killed five people exposed to inhalation anthrax through the mail. The UF findings could lead t...NIAID researchers show how promising TB drug works
...th, have determined how a promising drug candidate attacks the bacterium that causes tuberculosis (TB). Published online this week in Proceedings of the National Academy of Sciences, the finding may help scientists optimize the drug candidate, PA-824, which targets Mycobacterium tuberculosis (M. tb). "PA-8...Underlying cause of massive pinyon pine die-off revealed
... put the trees under so much water stress that the attacks from bark beetles finished them off. Under such conditions, the trees cannot make enough pine sap to defend themselves against the insects. "These trees are slow-growing trees, so we aren't going to have woodlands of this type back in this area for ...Genetic defenders protect crops from fungal disease
...mildew is a common fungal infection in plants that attacks more than 9,000 species, including many crops such...y mildew: Blumeria graminis hordei, a species that attacks barley, and Erysiphe pisi, one that thrives on the leaves and pods of pea plants. "Disabling just t...PET imaging reveals the immune system at work
...ses an unprecedented look at how the immune system attacks -- or sometimes promotes -- disease at the molecular level. It may help scientists and clinicians better evaluate specific immune responses to disease, making diagnosis and treatment more precise and effective. When confronted with disease, the immu...Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
...ses an unprecedented look at how the immune system attacks -- or sometimes promotes -- disease at the molecular level. It may help scientists and clinicians better evaluate specific immune responses to disease, making diagnosis and treatment more precise and effective. When confronted with disease, the immu...Scientists directly view immune cells interacting to avert autoimmunity
...senting dendritic cell -- in preventing autoimmune attacks of healthy tissue has been a focus of intense rese...e key cell types involved in initiating autoimmune attacks and the control of their actions by therapeutic regulatory T cells. The "nonobese diabetic" (nob) m...'Dating agency' boosts hunt for disease genes
...in gut, breast and white blood cell cancers, heart attacks and high blood pressure, depression, diabetes, kidney disease, multiple sclerosis, Parkinson's and Alzheimer's diseases, old age blindness, childhood asthma and eczema. The clinicians leading each national disease collection are based in London, Exet...HIV accessory protein disables host immunity via receptor-protein intermediary
...s called cytokines. This data demonstrate that Vpr attacks PARP-1 activity, so the mice are immune to toxins created by pathogens ?one indication that their immune surveillance has been compromised. Using biochemistry tests, the researchers were able to show that Vpr does interact with PARP-1 through the ...Researchers reverse juvenile diabetes in animal model
...now, scientists weren't sure why the immune system attacks the beta cells, but the result is that the body st...utoimmune disease because a person's immune system attacks and destroys the beta cells in the pancreas that produce insulin. Symptoms of type 1 diabetes usuall...New drug could reduce tissue damage after heart attack
...protein that contributes to tissue damage in heart attacks and strokes. The findings, published in the journ...esearch Council since 1979, says: "Although heart attacks are responsible for about one third of all deaths in developed countries, most patients survive a fi...Aspirin reduces cardiovascular risks in men and women -- but differently
...troke for women and reduction in the risk of heart attacks for men," Berger said. "While our analysis showed ...en and women, the relatively small number of heart attacks among women and strokes among men suggest that more research is needed to better understand any diff...Other ContentsabsorptionabsorptionabsorptionabsorptionabsorptionabsorptionabsorptionabsorptionacrosomeacrosomeactivationactivationactivationactivationactivationactivationactivationactivationactivationsitesitesitesitesitesitesitesitesitesiteactiveactiveactiveactiveactiveactiveactiveactiveactiveactiveradiationradiationradiationradiationradiationradiationradiationradiationradiationradiationadaptiveadaptiveadaptiveadaptiveadaptiveadaptiveOther TagsTransmissionTransmissionSportsTeenagerLongerLongerArtificialArtificialInheritanceRegulatingAntibodyAntibodyAntibodyAntibodyAntibodyRisingRisingRising
(Date:5/15/2008)... (BRONX, NY) Contrary to long-held assumptions, ..., according to investigators from the Albert Einst...y reached their conclusion after examining dietary...f adults in the U.S. The Einstein researchers actu...ath from cardiovascular disease (CVD) associated w...
(Date:5/15/2008)...ass.--MIT engineers have improved the power output...through technology that could help these environme... broader market, particularly in portable electron...considerably less expensive than its conventional ... Our goal is to replace traditional fuel-cell mem...
(Date:5/15/2008)...itute researchers Karen Staehling-Hampton, Ph.D., ...r Pourqui, Ph.D., Investigator, collaborated with ...s known to cause spinal mutations in chick and mou...man patients with congenital vertebral abnormaliti...Web site of the American Journal of Human Genetics...
(Date:5/15/2008)... Nottingham scientist and his celebrated brother w...e same graduation ceremony. Last year each brother...d the CBE. , The University of Nottingham Resear...S, and his brother, the acclaimed playwright and d...nised together for their remarkable contribution t...
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(Date:5/16/2008)... who would benefit most from chemo after surgery, ... News) -- A panel of 15 genes may help determine w... cancer will experience a recurrence and, therefor... shows. , By extension, the same genetic signa...ve forms of the cancer who would be able to forego...
(Date:5/16/2008)...RNewswire-USNewswire/ -- As tropical storms,contin...lta, survivors of,Cyclone Nargis are vulnerable to...s still need assistance, as exposure to the foul w...ly dire situation., "The people living in these c...this disaster and get back on their feet," said Da...
(Date:5/16/2008)...Death Drops More in 2007, WASHINGTON, May 16 /PRN...e in three cancer deaths, the National Cancer Inst...ion budget in lung cancer research in 2007,accord...liance (LCA) today., The two other federal agenci...nters for Disease Control and Prevention (CDC) and...
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