Angioplasty in Biological News

Promising 3-year data: Saving limbs with drug-eluting stents

... disease (PAD) patients with below-the-knee angioplasty are still thwarted by restenosis (the re-narrowing of the artery at the site of angioplasty or stenting), the need for repeat treatments and ... An interventional radiologist performs a balloon angioplasty to open a clogged blood vessel and then places a ...

Findings released from 1 of the largest percutaneous coronary intervention trials ever

... thrombin inhibitor bivalirudin during primary angioplasty had a reduced rate of adverse clinical events, a ... countries. A total of 3,602 patients undergoing angioplasty were randomly assigned to receive either ... bivalirudin instead of heparin with a GPI during angioplasty increases survival in heart attack patients who ...

New drug may reduce heart attack damage

... and tissue death resulting from life-saving interventions such as balloon angioplasty and stent placements, or from the delivery of clot-busting drugs. ... pain, and second, when the patient undergoes an intervention, such as angioplasty or stenting, to reopen the blocked artery". "At both these times a ...

Journal of Vascular and Interventional Radiology: New patient radiation safety guidelines

... chemoembolization for cancer); transjugular intrahepatic portosystemic shunt (TIPS) creation for liver disease; and renal and/or visceral artery angioplasty and/or stent placement. "The value of medical imaging is great and the risks of radiation dose are generally negligible compared to the health ...

Heart protein regulates blood vessel maintenance

... line blood vessels. Vascular smooth muscle cells undergo a process in diseases such as atherosclerosis or normal tissue damage caused by balloon angioplasty where they transition between a resting and proliferative state. The ability to transition between the two states is necessary for the normal ...

'Seeing' stem cells helps in fight against peripheral arterial disease

... pressure and cholesterol and control pain. Interventional radiologists treat severe cases of PAD with minimally invasive treatments, including angioplasty and insertion of stents. "However, some patients have extensive diseasewith so many blood vessels affectedthat they're difficult to treat," said ...

For old or young dialysis patients, AV fistulas remain pure gold

... poor blood flow. Interventional radiologists also keep AV fistulas or other accesses open or unclogged through minimally invasive techniques such as angioplasty or stenting. These interventions are safer, less costly and equally effective, and they improve the quality of life for dialysis patients. ...

12-month ATLANTA trial data show sustained benefit of Catania Stent

... of the United States in 60 sizes, in lengths from 8-38mm and in diameters from 2.0-4.0mm. "The CATANIA™ stent represents the next evolution in angioplasty treatment," said Thomas A. Gordy, President and Chief Executive Officer, CeloNova Biosciences, Inc. "Physicians, health care systems, and insurance ...

Human embryonic stem cell secretions minimized tissue injury after heart attack

... To minimise heart muscle damage and preserve the pumping action of the heart after a MI, early reperfusion by standard medical treatments such as angioplasty (commonly known as "ballooning") or bypass surgery is carried out in the hospital. Despite this, most MI patients suffer additional irreversible ...

At risk for peripheral arterial disease? Simple quiz provides key so you can circulate better

... changes (such as smoking cessation), diet and a structured exercise program. If needed, interventional radiologists can perform minimally invasive angioplasty and/or stenting to open a blocked artery in the leg and restore blood flow. In September, free testing is available for PAD at nearly 100 Legs for ...

Protecting those who heal

... to medical uses of X-ray imaging systems. The issue of radiation protection for medical personnel is particularly acute in the case of lengthy angioplasty and other cardiac interventions performed under X-ray fluoroscopic guidance. The procedure can cause extensive radiation exposure to cardiologists ...

New paradigm for cell-specific gene delivery

... for our future use of this technology to deliver therapeutic genes to lessen the severity of restenosis which is the most common issue following angioplasty and placement of stents". Dr. Dean continues, "Now that we have demonstrated proof of principle for this approach we can look for DNA sequences that ...

Rush Physicians Using Gene Therapy For Heart Patients With Moderate To Severe Chest Pains Who Do Not Benefit From Other Treatments

... but cannot also be candidates for treatment using angioplasty or bypass surgery. angioplasty involves a catheterization with a balloon-like ... well to either treatment, often requiring another angioplasty or bypass operation, noted Schaer. "If gene ...

Columbia study shows widely used artery clearing device does not help patients during heart attack

... microcirculatory protection, is commonly and successfully used during angioplasty in vein grafts and stenting in carotid arteries. The study, published in ... having heart attacks, half of whom received distal protection. During angioplasty procedures, fatty deposits in the arteries can be dislodged and clog ...

Protein therapy may reduce infarct size in heart attack patients

... the DCRI team evaluated KAI-9803 in 154 patients with anterior ST-elevation MI undergoing primary percutaneous coronary intervention with balloon angioplasty and coronary stent implantation. Patients were randomized 2:1 to receive intracoronary injections of the active study drug (KAI-9803) vs. placebo in ...

Reversing 'hibernating' heart muscle focus of UB researchers

... proteomic research facilities and mass spectrometry at UB. "By using therapies similar to those that are used clinically in patients, such as angioplasty and adenoviral gene transfer to over-express growth factors in the heart, we can identify how changes in the molecular pathways responsible for the ...

Potential heart benefit found in stem cells

... the thickness of the heart wall following a heart attack. To test the hypothesis, the researchers induced heart attacks in 17 pigs by way of an angioplasty balloon and harvested stem cells from the animals' subcutaneous fat tissues (ADSC, adipose derived stem cells). After repairing the hearts, a ...

Stem cell mobilization therapy appears to be ineffective in repairing damage caused by heart attack

... a heart attack), had successful reperfusion (restoration of blood flow) to the heart by percutaneous coronary intervention (procedures such as angioplasty in which a catheter-guided balloon is used to open a narrowed coronary artery) within 12 hours after onset of symptoms. Patients were randomly ...

Feds give researchers ok for safety test of adult stem cells in patients with heart disease

... In 2003, approximately 750,000 coronary artery bypass graft (CABG) surgeries were performed worldwide and approximately 1.8 million balloon angioplasty procedures were performed. While these interventional therapies are now the standard of care, there are still a significant number of people for whom ...

Bone marrow stem cells may heal hearts even years after heart attacks

... blood flow to the heart muscle as soon as possible, in order to limit the amount of permanent scarring. However, neither clotbusting drugs nor angioplasty can restore heart tissue that has already been damaged. Earlier studies demonstrated healing of heart muscle and improved heart function following ...