Airway in Biological News

Airway cells use 'tasting' mechanism to detect and clear harmful substances

... foods may also play a role in protecting your airway from harmful substances, according to a study by ... tongue also are found in hair-like protrusions on airway cells. In addition, the scientists showed that, unlike taste cells on the tongue, these airway cells do not need help from the nervous system to ...

Yale team identifies key to potential new treatment for allergy-induced asthma

... TRPA1. While the exact function of TRPA1 in the airway inflammation of asthma is not completely ... that also trigger asthma. TRPA1 is found in airway nerves that mediate pain and irritation and ... for TRPA1 had greatly diminished inflammation, airway mucus and bronchoconstriction." Furthermore, ...

Two-pronged model could help foil tough cystic fibrosis infections

... eliminate Pseudomonas established on CF airway cells. Last year, the DMS researchers reported ... were also studying iron overload in CF lungs. airway cells with the CF gene mutation release more ... is definitive for biofilms forming on live human airway cells. And the highest concentration of ...

Research finds new cause of ozone wheezing and potential treatments

... and Duke University have discovered a cause of airway irritation and wheezing after exposure to ozone, ... targets. They were also able to block the airway responsiveness by binding the native hyaluronan ... new approaches to the treatment of ozone-induced airway narrowing." Ozone has been estimated, in an ...

New asthma research opposes current drug treatment, says UH prof

... can negatively affect asthma control and airway hyperresponsiveness by desensitizing the beta-2 ... Inverseon Inc., eight of 10 patients had less airway hyperresponsiveness on beta-blocker therapy at ... applications for using beta blockers to treat airway disease. Dr. William Garner, chairman of ...

Research elucidates way lungs fight bacteria and prevent infection

... sickening assaults daily. It works like this: airway epithelial cells initiate an immune response to ... to move from the bloodstream into the lungs and airway to fight potential infection. For the first ... of opening the junctions between the cells in the airway mucosa, to enable the white blood cells to get ...

Adult stem cell breakthrough

... it is possible to produce a tissue-engineered airway with mechanical properties that permit normal ... edition of The Lancet . The loss of a normal airway is devastating, but previous attempts to replace ... should be replaced with a bioengineered airway based on the scaffold of a human trachea. A ...

Lung airway cells activate vitamin D and increase immune response

... that the activation step can also occur in lung airway cells. The study also links the vitamin D locally produced in the lung airway cells to activation of two genes that help fight ... presence of the enzyme 1 alpha-hydroxylase in the airway cells helps convert the storage form of vitamin D ...

OSA's ISP launches with research on breathing disorders and congenital heart defects

... by inserting a small medical stent into the airway to open it up and ease breathing. Critical to ... The current clinical practice for imaging the airway combines CT scans with "video endoscopy" images, ... and shape of the narrowing airways. Imaging the airway with aOCT, on the other hand, relies on inserting ...

Franklin Square to study airway bypass procedure for severe emphysema

... Center announces the start of the EASE (Exhale airway Stents for Emphysema) Trial to explore an ... widespread emphysema/COPD. The trial focuses on airway bypass, a bronchoscopic procedure designed to ... trapped air to exit the lungs. During the airway bypass procedure, new openings are created in ...

National Jewish Health researchers evaluating treatment to help emphysema sufferers breathe easier

... improve their quality of life." During the airway bypass procedure, new openings are created in the airway wall connecting the damaged lung tissue to the ... to the control or the treatment group. During the airway bypass procedure physicians will use a Doppler ...

Researchers at National Jewish Health evaluating a treatment

... improve their quality of life." During the airway bypass procedure, new openings are created in the airway wall connecting the damaged lung tissue to the ... to the control or the treatment group. During the airway bypass procedure physicians will use a Doppler ...

RSV may hide in the lungs, lead to asthma, UT Southwestern researchers report

... to cause recurrent wheezing and chronic airway disease. "This research suggests that there's ... the mice directly correlates with the severity of airway hyperreactivity. airway hyperreactivity, or episodes of bronchospasms in ...

Sentara begins international trial -- open at only 24 US locations

... Pulmonary Disease (COPD). The EASE (Exhale airway Stents for Emphysema) Trial focuses on airway bypass, an investigational technique without ... diminishing impact as the disease progresses. airway bypass, done without open surgery, is considered ...

Clinical trial that may help patients breathe easier begins at Central DuPage Hospital

... recently announced the start of the EASE (Exhale airway Stents for Emphysema) Trial to explore an ... widespread emphysema. The trial focuses on airway bypass, a minimally invasive bronchoscopic ... site for the EASE trial in the Chicago area. airway bypass could be groundbreaking because it is a ...

Severe asthma may be a different form of the disease

... who have severe asthma are more likely to have airway obstruction even after maximal treatment. The ... season. Inhaled corticosteroids, which reduce airway inflammation, can reduce the frequency and ... a volume of air. This is probably related to airway narrowing and is a hallmark of asthmatics, ...

Researchers at Sarasota Memorial Health Care System to study airway bypass treatment for emphysema

... today announced the start of the EASE (Exhale airway Stents for Emphysema) Trial, an international, ... The study focuses on a procedure called airway bypass that involves creating pathways in the ... By creating new pathways for airflow with the airway bypass procedure, we hope to reduce ...

HATS off to combat asthma

... 15 years has found that the muscle layer in the airway is more complex than has traditionally been ... these proteins are produced by stimulation of airway muscle cell walls in the lungs, releasing ... that may reduce the activation of HATs within airway cells, the researchers may isolate compounds that ...

Positive results for airway bypass

... Inc., a medical device company investigating the airway bypass procedure for the treatment of emphysema, ... in breathing for patients at six months after the airway bypass procedure. airway bypass is a catheter-based bronchoscopic ...

UC Davis grant zeroes in on novel asthma diagnosis and treatment

... treatment for treating inflammation," Hammock said. "Control of airway inflammation is critical in asthma treatment. We'll be investigating this ... Medical Center. "We believe these pathways are very important in the airway inflammation that occurs in asthma patients," said Kenyon, who directs ...

Vitamin D levels linked to asthma severity

... previous in vitro studies have suggested that vitamin D may affect how airway cells respond to treatment with inhaled steroids, this is the first in ... (FEV1) exceeded 65 percent of the predicted value were also tested for airway reactivity. They found that children with lower vitamin D levels were ...

Study helps explain connection between sleep apnea, stroke and death

... Journal of Applied Physiology . During sleep apnea episodes, the upper airway becomes blocked, hindering or stopping breathing and causing blood oxygen ... in your breathing. The treatment of obstructive sleep apnea with an airway pressurization mask has been shown to normalize cerebral autoregulation, ...

UCSF Fresno leading-edge study lends hope to emphysema patients

... with emphysema might soon be breathing a little easier thanks to a new airway bypass study called the Exhale Airways Stents for Emphysema (EASE) trial. ... support to keep the passageway open. Dr. Peterson said opening the airway allows the trapped air to escape the lungs, thereby hopefully relieving ...

Galloping and breathing at high speed

... very high (about 80 liters per second). Thus, a very small defect in the airway can cause a big decrease in performance. Two cartilages (the arytenoids ... the airflow and lead to a poor performance from the horse. An airway Solution for Horses and People? For the last three years the ...

USF professor gives historical look at physiology and WWII air war

... Fliers could withstand a rapid decompression as long as their airway was open, allowing air to flow out of their lungs as the surrounding ambient pressure dropped. If their airway was sealed, as during mid-swallow, then their lungs could over-pressure ...

Scientists discover how cigarette smoke causes cancer: Study points to new treatments, safer tobacco

... and colleagues describe how they exposed different sets of human lung airway cells (in the laboratory) to cigarette smoke and hydrogen peroxide. After ... were then incubated for one to two days. Then they, along with unexposed airway cells, were assessed for signs of cancer development. The cells exposed to ...

Breathless babies: Preemies' lung function shows prolonged impairment

... and development relative to body size was similar between the groups, but airway function was consistently lower in the premature infants at both ... persistent deficits in lung function.. These subjects have decreased airway function not only in the first few months of life, but also at the one ...

Athletes with asthma need more help from their team trainers

... Exercise-induced asthma occurs when airflow to the lungs is reduced due to narrowing and closing of the airways in association with exercise. This airway obstruction usually occurs just after exercise and is much more common in college athletes than in the general population. Symptoms include coughing, ...

Inhaling a heart attack: How air pollution can cause heart disease

... system. They have focused on smaller, microscopic particles that can get into the lungs and may gain entrance to the blood stream. (The upper airway filters out larger particles that are in smog and other air pollutants before they can cause a problem.) In addition, researchers have focused on ...

Study: Fluid buildup in lungs is part of the damage done by the flu

... kidneys. But in infected lungs, when the sodium channels are damaged, more and more fluid builds up in air spaces instead of being pumped across the airway lining and into the blood. "A little bit of fluid gives us a way to flush the nasties out of the lung," Davis said. "If you get a bacterial ...

Crib-side studies help struggling newborns go home without feeding tubes

... Gastroenterology and Nutrition , physicians at Nationwide Children's were able to help 15 out of 20 infants with severe feeding difficulties and airway concerns learn to feed by mouth. Successful feeders were sent home without the need for feeding tubes. These infants were referred to the ...

CT scans reveal that dinosaurs were airheads

... are modern day relatives of dinosaurs, as well as humans. The analysis of the predatory dinosaurs revealed large olfactory areas, an arching airway that went from the nostrils to the throat, and many sinusesthe same cavities that give us sinus headaches. Overall, the amount of air space was much ...

Synthetic virus supports a bat origin for SARS

... growth in cells," Denison said. The chimeric virus also grew well in mouse cells modified to express the receptor for SARS-CoV and in primary human airway epithelial cells. It grew poorly in mice, but a single additional change in the Spike region allowed efficient growth in mice, without causing a ...

Inherited genetic cause, possible treatment found for complex lung disorder

... of treatment that would be a major benefit to patients." The current front-line treatment is whole-lung wash, where a tube is inserted into the airway under anesthesia to flush out the lungs. People with PAP can also acquire secondary infections. This happens when immune system cells in called ...

New test promises quicker, more accurate evaluation for cystic fibrosis patients

... die of respiratory failure generally in their 30s or 40s. Lung damage is caused primarily by chronic bacterial infections and the resulting severe airway inflammation. There is a critical need for new effective anti-microbial and anti-inflammatory medications to slow and/or prevent lung damage in young ...

Sugar linkage could lead to better treatment for autoimmune diseases

... Center is demystifying the carbohydrate connections in cancer that contributes to metastatic growth and in avian flu where sialic residues on airway surface tissues serve as doorways for viral entry. Carbohydrates are the glue that pulls things together, the cell surface matrix in which cells ...

Possible link between baby swimming and breathing problems in children

... author and Department Director at the NIPHs Division of Epidemiology. Earlier studies indicated that there can be a link between baby swimming and airway infections in children. It has been suggested that indoor environmental factors (airway irritants) such as volatile chlorination products for indoor ...

CU-Boulder technology used to identify unexpected bacteria in cystic fibrosis patients

... respond to standard treatments, said Pace. "The results show molecular sequencing is a more effective, faster and far less expensive way to assess airway bacteria than routine clinical cultures and better identifies targets for further clinical evaluation," said Pace. Cystic fibrosis, a ...

Ozone can affect heavier people more

... the authors suggest that perhaps circulatory hormones and other inflammatory factors may play a role. These factors have been shown to affect airway hyper-responsiveness and inflammation in animal models. The authors note too that the study was limited in the small number of obese individuals ...

Stevens Health, Technology, and Society roundtable: Oct. 31

... and other related factors. Approximately 20 million Americans have been diagnosed with asthma, defined as a chronic inflammatory disease of the airway causing shortness of breath, tightness of the chest, coughing and wheezing. In addition, asthma and allergies strike 1 out of 4 Americans. The ...