Scientists discover gene mutation responsible for hereditary neuroendocrine tumor
... to extract energy from nutrients.
Studies in yeast
"Defects in mitochondria, the power sources ... decided to use a much simpler model system, the yeast
Saccharomyces cerevisiae, in order to study ... humans and determining whether what we learned in yeast
was also relevant to humans. Following this ...
Tryptophan deficiency may underlie quinine side effects
... at the University of Nottingham took advantage of yeast
genetics, examining the effects of quinine on a collection of 6000 yeast
mutants, each one lacking exactly one of the yeast's 6000 genes. While quite different from humans, yeast
is comparable on a cellular level ...
Discovery of the cell's water gate may lead to new cancer drugs
... the gate that regulates the flow of water into yeast
cells. The discovery, which will be published in ... determined the three-dimensional structure of the yeast
aquaporin. The results will be published in the ... unsolved mysteries of biology. The aquaporins in yeast
have long "tails", known as amino-terminal ...
Yeast missing sex genes undergo unexpected sexual reproduction
... DURHAM, N.C. An emerging form of the pathogenic yeast
Candida is able to complete a full sexual cycle ...
"Sex contributes to the Candida yeast
species' evolutionary success," said Joseph ... of drug resistance in this emerging pathogenic yeast
species. " ...
... A new species of yeast
has been discovered deep in the Amazon jungle. In a paper published on-line in FEMS yeast
Research , IFR scientists and colleagues from ... Each new species adds to our knowledge of the yeast
gene pool and even small genetic differences have ...
Rhythmic genomics -- the yeast metronome and the walk of life
... sequence information from the humble baker's yeast
has revealed surprising variation in a set of ... do occur, contrary to expectation, and yet the yeast
somehow still survives.
Furthermore, when two ... sequenced these genes to selectively identify yeast
species for over 15 years and had no idea they ...
Redefining what it means to be a prion
... the number of identifiable prion proteins in yeast
and have further clarified the role prions play ... as yeast.
Believing the number of prions in yeast
is higher than the four identified, researchers ... a high-throughput method to scan the entire yeast
genome, detect probable prion-coding sequences, ...
DNA repair mechanisms relocate in response to stress
... Biology . The journal's editors chose an image of yeast
cells with fluorescent DNA repair enzymes for the ... Keith Wilkinson, genetically modified strains of yeast
so that two different DNA repair enzymes would be ... able to follow the enzymes around the cell when yeast
was exposed to hydrogen peroxide, causing ...
Genetic sleuth solves glaucoma mystery
Walter and his team investigated a yeast
gene that is extremely similar to WDR36 but much ... the suspected WDR36 variations into the yeast
gene and tested its ability to function, and ... alone. The gene variations only affected the yeast
when there were simultaneous changes to another ...
Synthetic biology can help extend anti-malaria drug effectiveness
... their first success. By transplanting genes from yeast
and from the sweet wormwood tree into E. coli ... techniques to genetically engineer a strain of yeast
(Saccharomyces cerevisiae) that was capable of ... of anti-malarial drugs," said Keasling when the yeast
breakthrough was first announced.
Commercial yeasts upgraded with an enzyme for biofuel production
... has discovered a new enzyme which teaches yeast
cells to ferment xylose into ethanol. Xylose is ...
In industrial fermentation processes, the yeast
Saccharomyces cerevisiae is commonly used for ... succeeded in genetically modifying industrial yeast
strains, thus producing ethanol from xylose in a ...
New models question old assumptions about how many molecules it takes to control cell division
... Blacksburg, Va. -- A single cell whether a yeast
cell or one of your cells is exquisitely ... to accurately calculate the effects of noise in a yeast
cell revealed flaws in two accepted notions about ... the molecular fluctuations expected in a single yeast
cell? Physicists estimate molecular fluctuation ...
Calculating gene and protein connections in a Parkinson's disease model
... entered the data from screens of 5,500 yeast
strains ( Saccharomyces cerevisiae ). These strains are based on a yeast
model that creates large amounts of the protein ... says Fraenkel. "We have wonderful data from the yeast
model, but despite this richness of data, so ...
A budding role for a cellular dynamo
... that varies remarkably little from baker's yeast
to the human body. Part of the cytoskeleton, ... healthy and happily dividing.
Using baker's yeast
as the model organism, Brandeis researchers ... cell division, a process that not only allows yeast
to divide, but also ensures the proper renewal of ...
Genetic differences between yeasts greater than those between humans and chimpanzees
... The mapping of the entire yeast
genome in 1996 marked the beginning of a ... and functional genetics research. The lowly yeast
is, once again, leading the way.
In ... organisms from two different species of yeast
the common ...
Rewrite the textbooks: Transcription is bidirectional
... in Hinxton, UK, have now unravelled how yeast
generates its transcripts and have come a step ...
Investigating all transcripts produced in a yeast
cell, the scientists found that most regions of the yeast
genome produce several transcripts starting at ...
Evolutionary process more detailed than previously believed, study shows
... New evidence from a study of yeast
cells has resulted in the most detailed picture ... mostly theory.
Working with populations of yeast
cells, which were color-coded by fluorescent ... case in Kao's sample.
Observing the color-coded yeast
populations as they evolved to respond to their ...
Studies offer guide as protein interaction mapping comes of age
... One group's "map" of protein interactions in yeast
cells, for example, may only partially overlap ... about protein interactions: high throughput yeast
two-hybrid (HT-Y2H) procedures, which use robotic ... 12,000 interactions that have been identified in yeast
cells, 75 percent were reported in one study ....
Food can affect a cell in the same way hormones do
... as it uses to grasp the food for transport.
This research has been conducted on yeast
cells, as yeast
( Saccharomyces cerevisiae ) is a micro-organism ...
Penn scientists discover cells reorganize shape to fit the situation
... They were able to force normally rod-shaped yeast
cells to grow within tiny curved channels. Using ... Courtney Terenna, found was that if normal yeast
cells are forced to bend, their microtubules can ... tips. Conversely, they also found that mutant yeast
cells normally grow bent or round, if forced to ...
Growing fuel and medicine: Advancing biofuels and plant-produced therapeutics
... and Biotechnology, WPI
"The awesome power of yeast
(genetics)"an adaptation of a quote by Prof. ... elegant genetics possible in Bakers (or brewers) yeast
in the 1980s, which made it an object of envy of ... of drugs. Finally we are genetically modifying yeast
to increase ethanol production from cellulosic ...
Better beer: College team creating anticancer brew
... good bit of published literature about modifying yeast
with resveratrol-related genes. When they looked ... into creating a genetically modified strain of yeast
that will ferment beer and produce resveratrol at ... there's only one genetically modified strain of yeast
that's ever been approved for use in beer, ...
Wistar Institute researcher receives 'New Innovator' award from NIH
... he mapped an uncharted region of the fission yeast
genome and published the results in Science a ... to further elucidate genome dynamics in fission yeast
as a staff scientist at the National Cancer ... in September 2007. Noma's extensive research on yeast
informs his current work with the human genome. ...
Caltech engineers build mini drug-producing biofactories in yeast
... Hawkins, genetically modified common baker's yeast
(Saccharomyces cerevisiae) so that it contained ... for several plant enzymes. The enzymes allow the yeast
to produce a chemical called reticuline, which is ... from both plants and humans, which allowed the yeast
to efficiently generate large quantities of the ...
Duke-NIEHS team shows how DNA repairs may reshape the genome
... and Microbiology. "We have been able to show with yeast
that these repeated sequences allow the formation ... genome."
The scientists used X-rays to break yeast
chromosomes, and then studied how the damage was ... species."
The radiation-induced aberrations in yeast
were initially detected by co-author Jim ...
Zooming in on genetic shuffling
... map to date of recombination events in the yeast
"Our map has the highest resolution ... is 20 times higher than in any existing yeast
map and more than 360 times higher than a recent ... of recombination are likely to be shared between yeast
and humans. "Our map expands our understanding of ...
Arsenic and new rice
... genes coding for different NIP transporters into yeast
cells in order to test the cells for arsenic sensitivity. The researchers found that the growth of yeast
containing certain plant NIPs was suppressed when ... was channelled by NIPs and accumulated inside the yeast
cells. Further investigations showed that only a ...
Study finds Chinese food good for your heart
... that a partially purified extract of Chinese red yeast
rice, Xuezhikang (XZK), reduced the risk of ... in the Far East have been taking Chinese red yeast
rice as food for thousands of years, but no one ... the fact we do not know exactly how Chinese red yeast
rice works. The exact ingredients from the XZK ...
American Chemical Societys Weekly PressPac -- May 7, 2008
... development of a new kind of genetically modified yeast
cell that produces complex proteins up to 300 ... but inefficient protein-making machinery of yeast
cells. The result was a best-of-both worlds creation: A genetically-engineered yeast
cell that produces complex proteins containing ...
Genetic 'tag team' keeps cells on cycle
... human cells. Essentially everything that works in yeast
has its functional analog in mammalian cells, ... activity of about 6,000 genes over time in mutant yeast
cells that lacked functional cyclins.
Under ... an abrupt halt without cyclin. Instead, while the yeast
cells outwardly showed signs of the disruption ...
Researchers uncover details about how dietary restriction slows down aging
... restriction slows the aging process. Working in yeast
cells, the researchers have linked ribosomes, the ... UW researchers studied many different strains of yeast
cells that had lower protein production. They ... precisely what we found in the longer-lived yeast
strains with mutations in the large subunit of ...
MIT applies engineering approach to studying biological pathways
The MIT researchers focused on a pathway in yeast
that controls cells' response to a specific ... least 50 reactions. The pathway is activated when yeast
cells are exposed to a change in the osmotic ... Hog1 kinase, an enzyme with a pivotal role in the yeast
They exposed the cells ...
Diet and lifestyle critical to recovery, says study
... therapy in the future.
The team used bakers yeast
a model organism studied by biologists to reveal ... involved removing one of the two copies of all yeast
genes similar to removing one parents set of ... important, you would normally expect the yeast
to show a reduction in fitness, said Dr Daniela ...
Scientists uncover how hormones achieve their effects
... through which pheromones stimulate mating in yeast
have been gained by scientists at the European ... the interplay of signalling molecules in living yeast
cells, and to work out how they pass on a signal ... stimulating mating behaviour - by a nearby cell, yeast
cells form a projection that serves as a mating ...
UCI and CODA Genomics collaborate to re-engineer yeast for biofuel production
... new research aimed at turning a common strain of yeast
used in the production of beer, wine and bread ... algorithms to tweak the genetic structure of a yeast
strain called Saccharomyces. It has the ... in plant materials. In its natural state, the yeast
processes the glucose that grows in these ...
Evolution is driven by gene regulation
... for the difference between species at least in yeast
according to a report by Yale researchers in ... to find that even the closely related species of yeast
had extensively differing patterns of regulation. ... a group of closely and more distantly related yeast
whose sequences were well documented, we were ...
Reviews of microbial gene language published in special issue of Trends in Microbiology
... been used to assess the function of genes in Candida albicans , a type of yeast
that can lead to disease in humans. The characterization of genes in C. ... from the transfer of Gene Ontology terms from the extensively studied yeast
Saccharomyces cerevisiae . S. cerevisiae is another workhorse of the ...
Saved by junk DNA
... a complex experiment aimed at mimicking biological evolution, using yeast
cells as Darwinian guinea pigs. Their results show that when a repeat is present near a gene, it is possible to select yeast
mutants that show vastly increased activity of this gene. However, when ...
American Chemical Society's weekly PressPac -- May 6, 2009
... of these substances. The scientists then spliced these genes into Brewer's yeast
used to make beer and wine so that the yeast
cells churned out methyl halides instead of alcohol. In laboratory ...
Using combinatorial libraries to engineer genetic circuits advances synthetic biology
... timers was to assemble and test one in yeast, which could accurately time yeast
sedimentation -- a process that can be applied to biotechnology and some ... beer, wine and bioethanol fermentation, as it allows for easy removal of yeast
sediments after all the sugars have been converted to ethanol," the paper ...