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Yeast in Biological News

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

... to extract energy from nutrients. Studies in yeast "Defects in mitochondria, the power sources ... decided to use a much simpler model system, the yeast Saccharomyces cerevisiae, in order to study ... humans and determining whether what we learned in yeast was also relevant to humans. Following this ...

Tryptophan deficiency may underlie quinine side effects

... at the University of Nottingham took advantage of yeast genetics, examining the effects of quinine on a collection of 6000 yeast mutants, each one lacking exactly one of the yeast's 6000 genes. While quite different from humans, yeast is comparable on a cellular level ...

Discovery of the cell's water gate may lead to new cancer drugs

... the gate that regulates the flow of water into yeast cells. The discovery, which will be published in ... determined the three-dimensional structure of the yeast aquaporin. The results will be published in the ... unsolved mysteries of biology. The aquaporins in yeast have long "tails", known as amino-terminal ...

Yeast missing sex genes undergo unexpected sexual reproduction

... DURHAM, N.C. An emerging form of the pathogenic yeast Candida is able to complete a full sexual cycle ... "Sex contributes to the Candida yeast species' evolutionary success," said Joseph ... of drug resistance in this emerging pathogenic yeast species. " ...

Jungle yeast

... A new species of yeast has been discovered deep in the Amazon jungle. In a paper published on-line in FEMS yeast Research , IFR scientists and colleagues from ... Each new species adds to our knowledge of the yeast gene pool and even small genetic differences have ...

Rhythmic genomics -- the yeast metronome and the walk of life

... sequence information from the humble baker's yeast has revealed surprising variation in a set of ... do occur, contrary to expectation, and yet the yeast somehow still survives. Furthermore, when two ... sequenced these genes to selectively identify yeast species for over 15 years and had no idea they ...

Redefining what it means to be a prion

... the number of identifiable prion proteins in yeast and have further clarified the role prions play ... as yeast. Believing the number of prions in yeast is higher than the four identified, researchers ... a high-throughput method to scan the entire yeast genome, detect probable prion-coding sequences, ...

DNA repair mechanisms relocate in response to stress

... Biology . The journal's editors chose an image of yeast cells with fluorescent DNA repair enzymes for the ... Keith Wilkinson, genetically modified strains of yeast so that two different DNA repair enzymes would be ... able to follow the enzymes around the cell when yeast was exposed to hydrogen peroxide, causing ...

Genetic sleuth solves glaucoma mystery

... England. Walter and his team investigated a yeast gene that is extremely similar to WDR36 but much ... the suspected WDR36 variations into the yeast gene and tested its ability to function, and ... alone. The gene variations only affected the yeast when there were simultaneous changes to another ...

Synthetic biology can help extend anti-malaria drug effectiveness

... their first success. By transplanting genes from yeast and from the sweet wormwood tree into E. coli ... techniques to genetically engineer a strain of yeast (Saccharomyces cerevisiae) that was capable of ... of anti-malarial drugs," said Keasling when the yeast breakthrough was first announced. The ...

Commercial yeasts upgraded with an enzyme for biofuel production

... has discovered a new enzyme which teaches yeast cells to ferment xylose into ethanol. Xylose is ... In industrial fermentation processes, the yeast Saccharomyces cerevisiae is commonly used for ... succeeded in genetically modifying industrial yeast strains, thus producing ethanol from xylose in a ...

New models question old assumptions about how many molecules it takes to control cell division

... Blacksburg, Va. -- A single cell whether a yeast cell or one of your cells is exquisitely ... to accurately calculate the effects of noise in a yeast cell revealed flaws in two accepted notions about ... the molecular fluctuations expected in a single yeast cell? Physicists estimate molecular fluctuation ...

Calculating gene and protein connections in a Parkinson's disease model

... entered the data from screens of 5,500 yeast strains ( Saccharomyces cerevisiae ). These strains are based on a yeast model that creates large amounts of the protein ... says Fraenkel. "We have wonderful data from the yeast model, but despite this richness of data, so ...

A budding role for a cellular dynamo

... that varies remarkably little from baker's yeast to the human body. Part of the cytoskeleton, ... healthy and happily dividing. Using baker's yeast as the model organism, Brandeis researchers ... cell division, a process that not only allows yeast to divide, but also ensures the proper renewal of ...

Genetic differences between yeasts greater than those between humans and chimpanzees

... The mapping of the entire yeast genome in 1996 marked the beginning of a ... and functional genetics research. The lowly yeast is, once again, leading the way. In ... organisms from two different species of yeast the common ...

Rewrite the textbooks: Transcription is bidirectional

... in Hinxton, UK, have now unravelled how yeast generates its transcripts and have come a step ... Investigating all transcripts produced in a yeast cell, the scientists found that most regions of the yeast genome produce several transcripts starting at ...

Evolutionary process more detailed than previously believed, study shows

... New evidence from a study of yeast cells has resulted in the most detailed picture ... mostly theory. Working with populations of yeast cells, which were color-coded by fluorescent ... case in Kao's sample. Observing the color-coded yeast populations as they evolved to respond to their ...

Studies offer guide as protein interaction mapping comes of age

... One group's "map" of protein interactions in yeast cells, for example, may only partially overlap ... about protein interactions: high throughput yeast two-hybrid (HT-Y2H) procedures, which use robotic ... 12,000 interactions that have been identified in yeast cells, 75 percent were reported in one study ....

Food can affect a cell in the same way hormones do

... as it uses to grasp the food for transport. yeast vs. humans This research has been conducted on yeast cells, as yeast ( Saccharomyces cerevisiae ) is a micro-organism ...

Penn scientists discover cells reorganize shape to fit the situation

... They were able to force normally rod-shaped yeast cells to grow within tiny curved channels. Using ... Courtney Terenna, found was that if normal yeast cells are forced to bend, their microtubules can ... tips. Conversely, they also found that mutant yeast cells normally grow bent or round, if forced to ...

Growing fuel and medicine: Advancing biofuels and plant-produced therapeutics

... and Biotechnology, WPI "The awesome power of yeast (genetics)"an adaptation of a quote by Prof. ... elegant genetics possible in Bakers (or brewers) yeast in the 1980s, which made it an object of envy of ... of drugs. Finally we are genetically modifying yeast to increase ethanol production from cellulosic ...

Better beer: College team creating anticancer brew

... good bit of published literature about modifying yeast with resveratrol-related genes. When they looked ... into creating a genetically modified strain of yeast that will ferment beer and produce resveratrol at ... there's only one genetically modified strain of yeast that's ever been approved for use in beer, ...

Wistar Institute researcher receives 'New Innovator' award from NIH

... he mapped an uncharted region of the fission yeast genome and published the results in Science a ... to further elucidate genome dynamics in fission yeast as a staff scientist at the National Cancer ... in September 2007. Noma's extensive research on yeast informs his current work with the human genome. ...

Caltech engineers build mini drug-producing biofactories in yeast

... Hawkins, genetically modified common baker's yeast (Saccharomyces cerevisiae) so that it contained ... for several plant enzymes. The enzymes allow the yeast to produce a chemical called reticuline, which is ... from both plants and humans, which allowed the yeast to efficiently generate large quantities of the ...

Duke-NIEHS team shows how DNA repairs may reshape the genome

... and Microbiology. "We have been able to show with yeast that these repeated sequences allow the formation ... genome." The scientists used X-rays to break yeast chromosomes, and then studied how the damage was ... species." The radiation-induced aberrations in yeast were initially detected by co-author Jim ...

Zooming in on genetic shuffling

... map to date of recombination events in the yeast genome. "Our map has the highest resolution ... is 20 times higher than in any existing yeast map and more than 360 times higher than a recent ... of recombination are likely to be shared between yeast and humans. "Our map expands our understanding of ...

Arsenic and new rice

... genes coding for different NIP transporters into yeast cells in order to test the cells for arsenic sensitivity. The researchers found that the growth of yeast containing certain plant NIPs was suppressed when ... was channelled by NIPs and accumulated inside the yeast cells. Further investigations showed that only a ...

Study finds Chinese food good for your heart

... that a partially purified extract of Chinese red yeast rice, Xuezhikang (XZK), reduced the risk of ... in the Far East have been taking Chinese red yeast rice as food for thousands of years, but no one ... the fact we do not know exactly how Chinese red yeast rice works. The exact ingredients from the XZK ...

American Chemical Society’s Weekly PressPac -- May 7, 2008

... development of a new kind of genetically modified yeast cell that produces complex proteins up to 300 ... but inefficient protein-making machinery of yeast cells. The result was a best-of-both worlds creation: A genetically-engineered yeast cell that produces complex proteins containing ...

Genetic 'tag team' keeps cells on cycle

... human cells. Essentially everything that works in yeast has its functional analog in mammalian cells, ... activity of about 6,000 genes over time in mutant yeast cells that lacked functional cyclins. Under ... an abrupt halt without cyclin. Instead, while the yeast cells outwardly showed signs of the disruption ...

Researchers uncover details about how dietary restriction slows down aging

... restriction slows the aging process. Working in yeast cells, the researchers have linked ribosomes, the ... UW researchers studied many different strains of yeast cells that had lower protein production. They ... precisely what we found in the longer-lived yeast strains with mutations in the large subunit of ...

MIT applies engineering approach to studying biological pathways

... The MIT researchers focused on a pathway in yeast that controls cells' response to a specific ... least 50 reactions. The pathway is activated when yeast cells are exposed to a change in the osmotic ... Hog1 kinase, an enzyme with a pivotal role in the yeast salt-stress response). They exposed the cells ...

Diet and lifestyle critical to recovery, says study

... therapy in the future. The team used bakers yeast a model organism studied by biologists to reveal ... involved removing one of the two copies of all yeast genes similar to removing one parents set of ... important, you would normally expect the yeast to show a reduction in fitness, said Dr Daniela ...

Scientists uncover how hormones achieve their effects

... through which pheromones stimulate mating in yeast have been gained by scientists at the European ... the interplay of signalling molecules in living yeast cells, and to work out how they pass on a signal ... stimulating mating behaviour - by a nearby cell, yeast cells form a projection that serves as a mating ...

UCI and CODA Genomics collaborate to re-engineer yeast for biofuel production

... new research aimed at turning a common strain of yeast used in the production of beer, wine and bread ... algorithms to tweak the genetic structure of a yeast strain called Saccharomyces. It has the ... in plant materials. In its natural state, the yeast processes the glucose that grows in these ...

Evolution is driven by gene regulation

... for the difference between species at least in yeast according to a report by Yale researchers in ... to find that even the closely related species of yeast had extensively differing patterns of regulation. ... a group of closely and more distantly related yeast whose sequences were well documented, we were ...

Reviews of microbial gene language published in special issue of Trends in Microbiology

... been used to assess the function of genes in Candida albicans , a type of yeast that can lead to disease in humans. The characterization of genes in C. ... from the transfer of Gene Ontology terms from the extensively studied yeast Saccharomyces cerevisiae . S. cerevisiae is another workhorse of the ...

Saved by junk DNA

... a complex experiment aimed at mimicking biological evolution, using yeast cells as Darwinian guinea pigs. Their results show that when a repeat is present near a gene, it is possible to select yeast mutants that show vastly increased activity of this gene. However, when ...

American Chemical Society's weekly PressPac -- May 6, 2009

... of these substances. The scientists then spliced these genes into Brewer's yeast used to make beer and wine so that the yeast cells churned out methyl halides instead of alcohol. In laboratory ...

Using combinatorial libraries to engineer genetic circuits advances synthetic biology

... timers was to assemble and test one in yeast, which could accurately time yeast sedimentation -- a process that can be applied to biotechnology and some ... beer, wine and bioethanol fermentation, as it allows for easy removal of yeast sediments after all the sugars have been converted to ethanol," the paper ...
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(Date:4/17/2014)... One day about eight years ago, Katia Silvera , ... her father were on a field trip in a mountainous ... they had never seen before. , Unable to identify it, ... The orchid turned out to be an unnamed species. So ... . , "Lophiaris" is the genus name, comprising about 40 ...
(Date:4/17/2014)... of forests in the Amazon help create tinderbox ... rapid and widespread forest loss during drought years, ... show that forests in the Amazon could reach ... forest fires lead to large-scale loss of trees, ... professor of geography, Penn State. , "We documented ...
(Date:4/17/2014)... Current Biology on April 17 have discovered little-known ... insects, which represent four distinct but related species in ... of an animal with sex-reversed genitalia. , "Although ... Neotrogla is the only example in which ... from Hokkaido University in Japan. , During copulation, which ...
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(Date:4/17/2014)... new study has found that India,s shocking rates of ... farmers who are clinging to tiny smallholdings less ... crops, such as cotton and coffee, that are highly ... a range of previous case studies that point to ... following the ,liberalisation, of the nation,s economy during the ...
(Date:4/17/2014)... Giving patients adrenaline after they suffer a cardiac arrest ... of surviving long-term, according to new research conducted at ... who have a cardiac arrest get adrenaline, which has ... decades," said Dr. Steve Lin, an emergency physician and ... in medical treatment, long-term survival rates of patients who ...
(Date:4/17/2014)... its status as the leading weapon against the deadly ... with new research indicating it simply needs to be ... of the cheap anti-malarial drug chloroquine in treating and ... more than half a million people each year around ... developed resistance to chloroquine, but research carried out at ...
(Date:4/16/2014)... of the embryo. It begins as a glob of identical ... become the cells of our lungs, muscles, nerves and all ... a feat of reverse tissue engineering, Stanford University researchers have ... cells to proliferate and transform into all of the specialized ...
(Date:4/16/2014)... Celldex Therapeutics, Inc. (NASDAQ: CLDX) announced today that ... in solid tumors, including long-term patient follow-up, have been ... Issue 232). The data demonstrate robust antibody and T ... with very advanced cancers and suggest that CDX-1401 may ...
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