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Vessels in Biological News

Natural compound stops retinopathy

... American adults. It is caused by changes in blood vessels of the retina, the light-sensitive tissue at the ... In some people with diabetic retinopathy, blood vessels may swell and leak fluid. In other people, abnormal new blood vessels grow on the surface of the retina. Over time, ...

Major breakthrough in early detection and prevention of AMD

... (CNV) the invasive growth of new blood vessels in the thin vascular layer that provides ... vision loss occurs when these abnormal blood vessels invade the retina, the light-sensitive tissue ... the inner surface of the eyeball. "Once the vessels invade the retina, the horse has already left the ...

New evidence of how high glucose damages blood vessels could lead to new treatments

... levels that occur in diabetes damage blood vessels may lead to novel strategies for blocking the ... say. They found a decreased ability of blood vessels to relax resulted from increased activity of a ... finding that the more O-GlcNAc, the more blood vessels contract because these animals had higher ...

A longer lasting tumor blocker

... work by disrupting the formation of new blood vessels that feed growing tumors. Agents that block a ... was blocked. Blocking VEGF prevented dangerous vessels from growing such as those that feed tumors. But it also stopped beneficial vessels from growing, such as those that help injured ...

Building the lymphatic drainage system

... need continuous irrigation and drainage. Blood vessels feeding the tissues bring in the fluids, and ... system. While much is known about how blood vessels are built, the same was not true for lymph ... of lymph development when large, valve-containing vessels arise from more primitive capillaries. The study ...

Laughing hyenas, wailing levees, the sound of cheese and blaring bagpipes

... 3) GENE-LADEN BUBBLES GROW NEW BLOOD vessels Progress in human gene therapy -- the ... gene-laden microbubbles to the lining of blood vessels increased the amount of gene transfection. This ... successfully stimulated the growth of new blood vessels using UMGD with microbubbles carrying a gene for ...

Smoke from cigarettes, cooking oil, wood, shift male cardiovascular system into overdrive

... in indexes of sympathetic outflow to blood vessels than do women The sympathetic nervous ... that evoke responses from heart and blood vessels indicating effects on their function. This ... stress, but can cause harm to the heart and blood vessels if activated too often or too long. Women did ...

Smoke from cigarettes, cooking oil, wood, shift male cardiovascular system into overdrive

... in indexes of sympathetic outflow to blood vessels than do women The sympathetic nervous ... that evoke responses from heart and blood vessels indicating effects on their function. This ... stress, but can cause harm to the heart and blood vessels if activated too often or too long. Women did ...

Ambati study published in PNAS

... where growth of new blood and lymph vessels is believed to be a major cause of graft failure. ... new study found that siRNAs block not only blood vessels but also lymphatic vessels. In the cornea, the ... vessels. In fact, the formation of lymphatic vessels after corneal transplantation is purported to be ...

A missing enzyme conveys major heart protection in pre-clinical work

... therapy that could stimulate the growth of blood vessels and limit damage from a heart attack as well as ... growth in these animals. "There were blood vessels everywhere in these mice born without the ... example, but who might be able to grow new blood vessels in their legs." Stamler said his research ...

'Seeing' stem cells helps in fight against peripheral arterial disease

... how to use stem cells to create new or more blood vessels to treat peripheral arterial disease (PAD) in ... patients have extensive diseasewith so many blood vessels affectedthat they're difficult to treat," said ... target cell delivery in relationship to blood vessels without transferring to a separate CT scanner to ...

Pulmonary hypertension in children may result from reduced activity of gene regulator

... the remodeling that transforms flexible blood vessels into rigid pipes and the pulmonary hypertension ... the lungs, turning flexible pulmonary blood vessels into rigid pipes, said Dr. Black, who co-directs ... dysfunction is decreased ability of blood vessels to dilate and increased ability to thicken. ...

Society of Interventional Radiology hosts 34th annual scientific meeting

... rarely and may include injuries to the blood vessels that can cause prolonged and sometimes ... cell therapy to determine how to regenerate blood vessels to open clogged or narrowed arteries to treat ... by exploring the treatment of the smaller blood vessels below the knee (typically difficult to treat ...

Tiny tool to control growing blood vessels opens new potential in tumor research

... create targeted signals that instruct the vessels to go in a certain direction. This is of great ... tumor growth. Through the newly generated blood vessels in the vicinity of the tumor, tumor cells receive ... be to counteract the new formation of blood vessels in the tumor, thereby cutting off the supply of ...

Researcher seeks to turn stem cells into blood vessels

... stem cells to turn into networks of new blood vessels that could someday be used to replace damaged ... Which environmental cues cause them to form blood vessels instead of other types of body tissue? Is it a ... a lack of oxygen causes stem cells to form blood vessels in order to deliver more oxygenated blood to ...

Researchers explore new driver of transplant rejection: Platelets

... platelets line up in the interior of blood vessels feeding the tissue," Morrell says. "It turns out ... interactions with the inner lining of the blood vessels and worsened transplant vessel damage. "We watched platelets flowing through the blood vessels of transplanted skin in mice with and without ...

New technique images tumor vessel leakiness to predict breast cancer chemotherapy outcome

... from the bloodstream through the leaky blood vessels that often surround tumors. Predicting ... for determining the "leakiness" of tumor blood vessels using a simple digital mammography unit. The ... agent that could only leak into tumors with blood vessels that were growing and therefore leaky. The ...

Researchers may have found why women have an edge on salt-sensitive hypertension

... endothelin A, or ETA, receptors work in the blood vessels and tubules of the kidney. They also may help ... to raise blood pressure and help reshape blood vessels into thick, rigid pipes. ETA receptors have ... time the high-pressure pounding away at blood vessels can cause heart attack, stroke and/or kidney ...

Statins may treat blood vessel disorder that can lead to fatal strokes

... of statins. CCM is a disorder in which blood vessels in the brain become dilated and weakened, and ... and similar drugs, treat CCM by stabilizing blood vessels so they don't leak. CCM can be inherited ... does not form properly. When that happens, blood vessels can become weak and dilated, allowing them to ...

Researchers describe protease inhibitor that may aid in diabetic retinopathy treatment

... causes retinal swelling and destroys small blood vessels in the retina, eventually leading to vision ... or proliferative stage, and fragile new blood vessels grow along the retina. However, these fragile vessels can hemorrhage easily, and blood may leak into ...

Control of blood vessels a possible weapon against obesity

... exposed to low temperatures develop more blood vessels in their adipose tissue and metabolise body fat ... therefore be to affect the development of blood vessels in the adipose tissue. A team of researchers ... now demonstrated the rapid development of blood vessels in the adipose tissue of mice exposed to low ...

Peering inside the skull of a mouse to solve meningitis mystery

... that begins with leakage of fluid from blood vessels into the meninges, the protective covering of the ... could not be causing fluid to leak from the blood vessels into the meninges. If T-cells weren't the ... blood cells breaking through the walls of blood vessels into the meninges, opening the floodgates for ...

Columbia University scientist devises new way to more rapidly generate bone tissue

... process involving the growth of new blood vessels from pre-existing vessels has been a major roadblock in tissue ... these problems: artificially fabricated blood vessels do not readily branch out and network with host ...

Step out for PAD

... and multiplying the surrounding smaller blood vessels in the area, called collateral blood flow. The ... on regular exercise training. The collateral vessels themselves were larger and less prone to ... animals. Surprisingly, the function of blood vessels 'downstream' of the blockage also changed, making ...

Reprogrammable cell type depends on a single gene to keep its identity

... how during embryogenesis a critical set of vessels called the lymphatic vasculature arises from veins; and how lymphatic vessels can eventually lose their characteristics and acquire features typical of blood vessels and transport blooda trick that might, for ...

Einstein researchers develop a new way to study how breast cancer spreads

... found that breast cancer cells closer to blood vessels were more aggressive and directed in their ... from blood vessels. The cancer cells near blood vessels also appeared in the lung indicating that they ... link was shown between the presence of blood vessels and the invasive ability of a cancer cell, which ...

Study may explain exercise-induced fatigue in muscular dystrophies

... location on the muscle membrane, then blood vessels that supply active muscles do not relax normally ... showed post-exercise constriction of the blood vessels supplying muscle. Blocking nNOS activity in ... produced post-exercise fatigue and narrowed blood vessels to the muscles. The team also found that ...

Where optics meets medicine

... devastating loss of brain tissue, but small blood vessels get occluded too, and much more frequently than ... to study the effect of blockages in small blood vessels on the health and function of nearby neurons. ... laser and nonlinear optics to target and clot vessels of the venule system and then monitor the effect ...

LSUHSC awarded patent for compound inhibiting cancer and other diseases

... for a compound to inhibit the formation of blood vessels critical to the growth of cancerous tumors and ... that it can be used to destroy existing blood vessels as well as prevent the development of new ... will be able to control the growth of new blood vessels that would feed tumors," notes Dr. Woltering. ...

Pittsburgh researchers identify source of multipotent stem cells with broad regenerative potential

... of adult stem cells found on the walls of blood vessels with the unlimited potential to differentiate ... Pericytes are found on the walls of small blood vessels such as capillaries and microvessels throughout ... encouraging aspect of this source is that blood vessels are the one structure that all tissues in the ...

Better understanding of blood vessel constrictor needed to harness its power for patients

... harness endothelin-1's power to constrict blood vessels and help patients manage high blood pressure or ... receptors are known to interact: one way blood vessels keep a healthy tone, for example, is that a and b ... while b receptors on the lining of blood vessels work with nitric oxide to promote relaxation. ...

Protein identified that plays role in blood flow

... have known that high blood pressure causes blood vessels to contract and low blood pressure causes blood vessels to relax. Until recently, however, researchers ... with very high resolution - and isolating blood vessels outside the body, University of Missouri ...

Gap junction protein vital to successful pregnancy, researchers find

... protein that is vital to the growth of new blood vessels that sustain the embryo. Without this protein, ... is essential to the rapid growth of new blood vessels needed to support the development of the embryo ... growth. "The formation of these new blood vessels is extremely critical for embryonic growth at ...

Gene is likely cause of stroke-inducing vascular malformations

... discovered that a gene controlling whether blood vessels differentiate into arteries or veins during ... connection produces enlarged, tangled masses of vessels that are prone to hemorrhagic rupture, bleeding ... brain cells, which are the cells lining blood vessels in the brain, and found that BAVMs were induced. ...

Normalizing tumor vessels to improve cancer therapy

... is not always effective, because the blood vessels feeding the tumors are abnormal"leaky and twisty" ... of Sciences . A tumor's capillariessmall blood vessels that directly deliver oxygen and nutrients to ... leakiness. "These abnormal features of tumor vessels impair delivery of circulating chemotherapeutic ...

Slipping through cell walls, nanotubes deliver high-potency punch to cancer tumors in mice

... how they interacted with the walls of the blood vessels through which they circulated after being ... this instance the relatively leaky walls of blood vessels in the tumor tissue provided the opening that the ... vessel walls are slightly porous, but in healthy vessels the pores are relatively small. By tinkering with ...

Vitamin A pushes breast cancer to form blood vessel cells

... cells. These cells can then build blood vessels to link up to the body's blood supply, promoting ... angiogenesis, when tumors send signals to blood vessels to grow toward the cancer. The study's senior ... may cause some breast cancer cells to form blood vessels brings up the rather disturbing notion that ...

Certain anticancer agents could be harmful to patients with heart disease

... are on the forefront of research into how blood vessels in heart muscle develop in growing embryos. They ... of adult mice caused many small coronary blood vessels to disappear, leaving heart muscle short of ... essential to maintain a healthy supply of blood vessels in heart muscle in adult organisms. "Nobody ...

New discoveries from Harvard and Baylor get to the heart of cardiovascular disease

... reduces inflammation in the walls of blood vessels provoked by fatty deposits (atherosclerosis). In ... and rabbit food, sooner or later our blood vessels rot," said Gerald Weissmann, MD, Editor-in-Chief ... that may heal into the natural arteries and blood vessels as time goes on. Find out more about this by ...

T-cadherin affects blood vessel growth in breast cancer, hormone from fat cells may play a role

... and the formation and development of blood vessels that feed breast tumors. Like mortar between ... T-cadherin, and in tumors, only the blood vessels that supply oxygen and nutrients express this ... the knockouts were deficient in growing new blood vessels to the graft. Stunting blood vessel growth ...
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