New lab test offers better prediction of HIV microbicide safety
... scientists have been trying to develop a topical vaginal
microbicide for preventing transmission of HIV, ... for signs that the chemical inflames cells of the vaginal
lining, or epithelium. That could cause more harm ... a microbicide's safety. The cells of the vaginal
epithelium normally are tightly packed together, ...
American Chemical Society's Weekly PressPac -- Aug. 27, 2008
ARTICLE #4 FOR IMMEDIATE RELEASE
proteins in HIV-resistant prostitutes suggest new ... suggests that certain biological factors in their vaginal
fluid may play a role in resistance, the exact ... method to compare differences among proteins in vaginal
fluids from HIV-resistant women and those ...
Vaginal reconstruction not needed for most inter-sex females, Hopkins study shows
... from the Johns Hopkins Childrens Center say vaginal
reconstruction should be a matter of preference ... undescended testes that do require removal.
surgery, if needed or wanted, should be done ... most girls born with this condition should have vaginal
reconstruction in order to be sexually active, ...
Risk of common vaginal infection linked to preterm birth appears higher for blacks
... BOSTON, Aug. 11 Risk of a common vaginal
infection linked to preterm birth appears to ... BV is characterized by an increase in vaginal
alkalinity and an overgrowth of abnormal ... But we dont even know the differences in normal vaginal
flora among racial groups, he said. More study is ...
NIH expands Human Microbiome Project; funds sequencing centers and disease projects
... Transmitted Diseases
This study will look at changes in the vaginal
microbiome and its association with environmental factors, diseases and a ... Vagina: Bacterial Vaginosis
This study will assess the vaginal
microbiome and whether it contributes to the risk of bacterial vaginosis, ...
Re-awakening old genes to help in the fight against HIV
... A new vaginal
cream containing a reawakened protein could someday prevent the ... prevent the transmission of HIV. He applied aminoglycoside antibiotics to vaginal
tissues and cervical cells in his lab and found the antibiotic appears to ...
Complications early in pregnancy or in previous pregnancies adversely affect existing or subsequent pregnancies
... in the first trimester of an ongoing pregnancy, this increased the risk of further
complications later on in the same pregnancy. For instance, vaginal
bleeding in the first trimester increased the
risk of preeclampsia, premature or very premature delivery and more than doubled the risk of low birth ...
Yeast missing sex genes undergo unexpected sexual reproduction
... with another organism without affecting the other. Humans are susceptible to three types of yeast infection: thrush (in the mouth and throat), vaginal
infection, and a sometimes fatal systemic infection of bloodstream and organs, such as the kidney.
In a paper published online May 24 in Nature , ...
Low levels of vitamin D linked to common vaginal infection in pregnant women
... PITTSBURGH, May 22 Pregnant women with low levels of vitamin D may be more likely to suffer from bacterial vaginosis (BV) a common vaginal
infection that increases a woman's risk for preterm delivery, according to a University of Pittsburgh study. Available online and published in the ...
Vitamin D insufficiency linked to bacterial vaginosis in pregnant women
... Bacterial vaginosis (BV) is the most common vaginal
infection in US women of childbearing age, and is common in pregnant women. BV occurs when the normal balance of bacteria in the vagina is disrupted ...
Study: Health undervalued in reproductive rights debate
... procedure and heighten risks, Burkstrand-Reid said.
Other cases blame women themselves when services are denied, such as when women are refused vaginal
delivery and forced instead to have cesarean sections because judges reason they should have addressed that question sooner.
"We pay a lot of ...
Oh baby, interventional radiology makes childbirth safer
... a common means of birthing today; it involves making a surgical incision in the mother's uterus to deliver the baby. Most C-sections are done when a vaginal
delivery would put either the baby's or mother's health at risk. The rate of C-sections in the United States has risen greatly over the past decade, ...
Repeat C-section before 39 weeks raises risk of neonatal illness
... rate in the United States has risen dramatically, from 20.7 percent in 1996 to 31.1 percent in 2006. A major reason is the decline in attempted vaginal
births after cesarean. Because elective cesareans can be scheduled to accommodate patient and physician convenience, there is a risk that they may be ...
Gaining too much weight during pregnancy nearly doubles risk of having a heavy baby
... Kaiser Permanente Center for Health Research in Oregon and Hawaii. "A big baby also poses serious risks for both mom and baby at birth--for mothers, vaginal
tearing, bleeding, and often C-sections, and for the babies, stuck shoulders and broken collar bones. "
While researchers have known for some ...
Natural childbirth linked to stronger baby bonding than C-sections
... it hard to assess the significance of the findings without replication and follow-up studies. "I suspect that the parental brain is 'primed' by vaginal
delivery and affected by neurohormonal factors such as oxytocin, a hormone linked to emotional connections and feelings of love," said Swain. ...
UT pathologists believe they have pinpointed Achilles heel of HIV
... are now under development for HIV immunotherapy by infusion into blood. They could also be used to guard against sexual HIV transmission as topical vaginal
or rectal formulations.
"HIV is an international priority because we have no defense against it," Paul said. "Left unchecked, it will likely ...
More than words: childbirth training change improves safety, cuts unnecessary procedures
... Health Research. The study was implemented between September 2003 and December 2005 at 19 public maternity hospitals that had at least 1,000 vaginal
deliveries each year, and no explicit policy for episiotomy or active management of the third stage of labor.
This randomized trial showed that ...
Continuous oral contraceptives better at easing pain, bleeding
... cyclical or continuous birth control pills, for six months with both researchers and participants blinded to the study group.
"We monitored vaginal
bleeding, quality of life, and ovarian and endometrial suppression," said Legro, whose team's findings appeared in a recent issue of the Journal of ...
Scientists launch human oral microbiome database
... and infectious disease communities, said Dr. Dewhirst. We hope that the information in this Database can serve as a model for the gut, skin and vaginal
databases for the Human Microbiome Project.
This project is supported by National Institute for Dental and Craniofacial Research, (NIDCR). In ...
Bacterial infections in premature babies more common than previously realized
... lacking cell walls): Ureaplasma urealyticum and Mycoplasma hominis.
Although Ureaplasma urealyticum and Mycoplasma hominis are found in 80% of vaginal
and cervical fluids, infants are not generally screened for these bacterial infections. The finding that about one-quarter of early preterm infants ...
NIH hosts event to launch Council of Science Editors' global theme issue
... of Infectious Diseases and presented by Dr. Maria Yazdanbakhsh, Leiden University Medical Center (Leiden, The Netherlands)
and neonatal wipes in home births in Pakistan: A randomized controlled trial, published by Obstetrics & Gynecology and presented by Dr. Sarah Saleem, ...
Scientists sequence genome of parasite responsible for common sexually transmitted infection
... vagina, resulting in heavy yellow-green or gray vaginal
odor, discomfort during sexual intercourse and ... cells, causing direct damage to the urinary and vaginal
tissues and resulting in inflammation. T. ...
Researchers discover new details about HIV-1 entry and infection
... separated and removed the outer lining of vaginal
cells, which serves as the first barrier to the virus. The isolated preparation of intact, viable, vaginal
epithelium permitted examination of immune cells that normally migrate out of the vaginal
epithelium into deeper tissues shortly after ...
Anti-HIV drug has potential to prevent transmission in women
... to treat HIV is also safe when applied as a vaginal
microbicide gel. Microbicides are designed to ... transmitted diseases and may be formulated as vaginal
gels, foams, creams, or suppositories.
"The ... online, the multi-site study suggests that as a vaginal
gel, tenofovir produced mild or no side effects ...
Vaginal gel may provide a new approach to HIV prevention
... shown that three different anti-viral agents in a vaginal
gel protect the animals against an HIV-like ... the compounds evaluated in the study as potential vaginal
microbicides to protect women from HIV. Under ... in women result from heterosexual intercourse. A vaginal
gel containing microbicides could be applied ...
Harmful chemicals may reprogram gene response to estrogen
... (DES), a synthetic form of estrogen linked to vaginal
cancer, the incidence of uterine tumors rises to ... and preterm deliveries, infertility, and a rare vaginal
and cervical cancer called clear-cell ... While DES exposure can lead to the development of vaginal
and cervical cancers, the fact that most ...
Common parasitic infection leads to increased risk for HIV infection
... etc." said McClelland.
The study pointed to several reasons why vaginal
trichomoniasis could possibly lead to an increased risk of HIV ... step, McClelland suggested that "comprehensive strategies for reducing vaginal
infections and addressing potentially harmful intravaginal practices such ...
UCSF study will test new vaginal microbicide for herpes and HIV
... women to participate in the first U.S. study of the safety of a new a vaginal
gel designed to prevent herpes and HIV infection.
If it is effective and ... of Health and World Health Organization to support the development of vaginal
microbicides," said Moscicki, who also is the director of Teen Clinics in ...
Friendly bacteria in humans may protect against HIV
... are strains of lactobacillus, commonly found colonizing the oral and vaginal
cavities of humans. They do not cause disease. They target HIV because the ... bacteria that target mannose, Tao and his colleagues isolated oral and vaginal
lactobacilli from healthy humans and tested the ability of different ...
Study shows dramatic increase in Caesarean sections
... mothers or babies, and should be based on solid medical reasons to ensure the best outcome."
In the most recent five year period, spontaneous vaginal
births had dropped by 5 per cent, while forceps and vacuum assisted deliveries were down by 15 per cent. ...
Anti-herpes treatment reduces HIV levels in women infected with both viruses
... to acquire or transmit HIV are also required. A number of options to prevent HIV transmission are currently being investigated, including the role of vaginal
microbicides, pre-exposure HIV prophylaxis, male circumcision, and - in the future - an HIV vaccine.'
'The results of the trial are striking', ...
Study defines effective microbicide design for HIV/AIDS prevention
... of 15 and 24 are more than three times higher than among their male counterparts.
Women are about twice as likely as men to contract HIV during vaginal
intercourse, according to the federal Centers for Disease Control and Prevention. In developing countries particularly, cultural and socioeconomic ...
Report focuses on the role good microbes play in future medicine
... bowel syndrome and inflammatory bowel disease, oral diseases like tooth decay and periodontal disease, and various other infections, including vaginal
infections and possibly skin infections. Probiotics could also conceivably be put to use in preventing disease or thwarting autoimmune disorders. A ...
Defense peptide found in primates may block some human HIV transmissions
... be applied to the vagina in the form of a gel or cream. Many of the laboratory tests have shown that retrocyclin can prevent HIV-1 infection of human vaginal
Retrocyclin was still an effective inhibitor of HIV-1 even after 100 days of continuous exposure to human cells in a laboratory setting. ...
U of M researchers discover genetic key to treating deadly fungal infections
Candida albicans, a type of yeast present in 80 percent of humans, is usually harmless. In otherwise healthy people, it can cause mild oral and vaginal
infections (candiasis or thrush) that are easily treated. But in people whose immune systems are suppressed (by AIDS, chemotherapy, or drugs for ...
MUHC investigators search for the root of sexual pain in women
... focus on the role of fear in sexual intercourse--the major roadblock to therapeutic efforts. "Women suffering from vaginismus seem to avoid and fear vaginal
penetration more than women suffering from other genital pain disorders," noted Dr. Binik. "A better understanding of the specific features of both ...
Living anti-HIV gel shows early promise
... Scientists are one step closer to developing a 'living gel' that could be applied to the vaginal
or intestinal tracts to protect against HIV/AIDS infection.
The researchers genetically modified bacteria that are normally present in the body to ...
'Patient-choice' C-section rate rises 36%: HealthGrades study
... an opinion supporting C-sections by patient choice "�so long as the patient is fully informed of the risks and benefits of this procedure over vaginal
Sleeping Sickness Epidemic Spreading in Uganda
... assigned at random to receive misoprostol. The rest of the women underwent vacuum aspiration. The women in the misoprostol group were treated with 4 vaginal
doses of misoprostol, each containing 200 mcg. of the drug. If the uterus had not expelled its contents by the end of three days, the women received ...