Vaccine in Biological News

More than half of Texas physicians do not always recommend HPV vaccine to girls

... The quadrivalent human papillomavirus (HPV) vaccine has been mired in controversy since it was ... 48.5 percent said they always recommend the HPV vaccine to girls, 68.4 percent said they were likely to recommend the vaccine to boys and 41.7 percent agreed with mandated ...

Pitt researchers find promising candidate protein for cancer prevention vaccines

... and neck cancers. The finding suggests that a vaccine against the protein might prevent malignancies in ... we can be more confident about the safety of a vaccine strategy to immunize high-risk groups against ... year, a clinical trial of a cyclin B1 treatment vaccine in lung cancer patients, and she plans to assess ...

First genetically-engineered malaria vaccine to enter human trials

... the malaria parasite that will be used as a live vaccine against the disease. The vaccine, developed in ... and Immunity division, said in developing the vaccine the research team had deleted two key genes in ... malaria infection. He said it was hoped the vaccine would produce similar results in humans. ...

Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma

... distant metastatic melanoma were injected with a vaccine that included each patient's own immune cells ... in the laboratory. The patient-specific vaccine is designed to stimulate the patient's immune ... p=.016). Eight patients in the dendritic cell vaccine study experienced remarkable long-term, ...

Vaccine blocks malaria transmission in lab experiments

... vaccine. Antibodies induced by Pfs48/45 protein vaccine effectively blocked the sexual development of the ... of a successful transmission-blocking vaccine is an essential step in efforts to control the ... and basis for testing a transmission-blocking vaccine in humans," said Nirbhay Kumar, PhD, senior ...

Ethiopian government celebrates rinderpest eradication

... Family Medicine at TUSM, repurposed a rinderpest vaccine that could be transported to rural areas without refrigeration. Delivery of the previous vaccine was problematic due to heat sensitivity. FIC's ... damaged the food supply and the economy. A vaccine commonly known as the ...

Penn-Wistar team gains insight into HIV vaccine failure

... publicized failure in 2007 of the Merck STEP HIV vaccine study that cast doubt on the feasibility of HIV-1 ... 20 in Nature Medicine . The phase II STEP vaccine trial was stopped after an interim analysis ... the adenovirus 5 (Ad5) vector used to deliver the vaccine actually showed a trend toward an increased rate ...

UTSA infectious disease researchers advancing vaccine against Valley fever

... have genetically engineered a live, attenuated vaccine that successfully protects mice against Valley ... as coccidioidomycosis. A live, attenuated vaccine is used as a preventative treatment based upon ... studies in the hopes of developing a vaccine to better protect those who are exposed to it in ...

Targeting children effective use of limited supplies of flu vaccine and could help control flu spread

... predict, it is unlikely that supplies of the new vaccine will be sufficient to vaccinate entire ... it effectively, particularly where supplies of vaccine are not sufficient for universal coverage. The ... effect would mean that significantly less vaccine would be necessary to help control the spread of ...

Government of Canada announces funding for research on the H1N1 flu virus

... influenza research network focused on pandemic vaccine evaluation. The network will strengthen Canada's ... safety and effectiveness of a pandemic influenza vaccine and vaccination programs. The network was ... and delivery of an effective influenza vaccine are critical to addressing the H1N1 flu virus, ...

Swine flu experts gather at New York Academy of Sciences May 28

... new recombinant virus, epidemiology, treatment, vaccine development and the public health implications of ... developed the first genetically engineered vaccine of any kind more than 30 years ago. He is an ... of producing some 450 million doses of a new vaccine each year. Dr. Bucher is the symposium organizer. ...

Preventing ear infections in the future: Delivering vaccine through the skin

... An experimental vaccine applied the surface of the skin appears to ... this disease. "We have designed several vaccine candidates which target proteins on the outer ... immunization by injection, each of the three vaccine candidates prevented experimental ear infections ...

Novel vaccine approach offers hope in fight against HIV

... approach that bypasses the usual path followed by vaccine developers. By using gene transfer technology ... that was the target of all previous HIV and SIV vaccine candidates," said study leader Philip R. Johnson, ... this animal study might be translated into an HIV vaccine for humans. If the technique leads to an ...

Princeton team's analysis of flu virus could lead to better vaccines

... scientists may have found a better way to make a vaccine against the flu virus. Though theoretical, ... then this might constitute a new approach to vaccine design. Indeed, the perplexing pattern of ... antibodies bind. Such variants would make ideal vaccine strains, guiding the immune system to produce two ...

Avian flu research sheds light on swine flu outbreak

... virus is different from the virus upon which the vaccine is modeled, it may mean that current vaccine stocks would not be as effective against the H9N2 ... strain. Perez will likely do studies related to vaccine development, virus transmission between humans ...

Alzheimer's, asthma, cancer, malaria and TB focus of new Singapore grants

... studies will examine the mechanisms of an oral vaccine against the predominant allergen, the "Blo t 5" ... eczema. Optimizing the potency of a genetic vaccine against the dust mite will be the focus of her ... t 5, to develop a novel and effective therapeutic vaccine for immunotherapy," she added. Grants also ...

UTSA, Health Science Center collaborate with Merck & Co. to develop chlamydia vaccine

... agreement with Merck & Co., Inc., to develop a vaccine for chlamydia, targeting the common sexually ... animal models of genital chlamydial infection, a vaccine composed of a select group of recombinant C. ... to provide payments to the university as vaccine candidates advance through development and are ...

Caltech scientists show why anti-HIV antibodies are ineffective at blocking infection

... spawned a worldwide search for an effective vaccine against the human immunodeficiency virus (HIV), ... shed more light on why developing an effective vaccine for HIV has proven so elusive." Y-shaped ... Health Initiative and the Collaboration for AIDS vaccine Discovery. ...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

... CHICAGO - An experimental vaccine that triggers the patient's immune system to ... University Medical Center are researching the vaccine called MAGE-A3 Antigen-Specific Cancer ... non-small-cell lung cancers. The experimental vaccine targets MAGE-A3, a protein expressed in certain ...

A natural approach for HIV vaccine

... Immunology, suggests that an effective HIV vaccine may come from a shotgun approach using of a wide ... should make people think about what an effective vaccine should look like." HIV strains mutate ... high-profile super antibodies on which several vaccine attempts have been based. But in high ...

K-State researchers help Epitopix license the United States' first E. coli O157 vaccine for cattle

... LLC, have resulted in the United States' first vaccine against E. coli O157 in beef cattle. ... "We're really excited about the potential of this vaccine to aid pre-harvest food safety in beef cattle." ... Texas A&M University. "We're excited that this vaccine has been granted a conditional approval by the ...

Researchers identify new way the malaria parasite and red blood cells interact

... cells, which could lead to the development of a vaccine cocktail to fight the mosquito-borne disease. ... the road, the EBL-1 molecule could be used as a vaccine target against malaria as part of a multivalent vaccine, or vaccine cocktail," said principal investigator Ghislaine ...

HIV adapts to 'escape' immune response

... body's defense system that any successful AIDS vaccine must keep pace with the ever-changing ... distinct hosts, the challenge ahead in vaccine design is formidable," he said. The ... just beginning to understand. The future of vaccine exploration will need to address the escape ...

Scientists identify human monoclonal antibodies effective against bird and seasonal flu viruses

... therapies to contain the outbreak until a vaccine became available. The production of a new influenza vaccine takes six to nine months using conventional ... they are not always effective because the vaccine must be updated each year. Vaccines against H5N1 ...

Scientists identify human monoclonal antibodies effective against bird, seasonal flu viruses

... therapies to contain the outbreak until a vaccine became available. The production of a new influenza vaccine takes six to nine months using conventional ... they are not always effective because the vaccine must be updated each year. Vaccines against H5N1 ...

African-Americans aware and accepting, but often do not receive, the HPV vaccine

... concerned about the long-term efficacy of the vaccine or its possible side effects. Most famously, ... they did not outweigh their positive views of the vaccine as an option. Researchers surveyed 71 females ... or "very good" idea and they generally viewed the vaccine as "safe," "effective" and a "wise choice." ...

New vaccine developed for preventing 'uncommon cold' virus

... Academy of Sciences have developed a DNA-based vaccine that has effectively protected mice from the ... February 18, 2009 print edition of the journal vaccine and are currently available online ( ... the future, this simple, stable and inexpensive vaccine can be mass-produced and made available to ...

Vaccines and autism: Many hypotheses, but no correlation

... having a real impact on public health, he added. vaccine refusal is contributing to the current increase ... the combination measles-mumps-rubella (MMR) vaccine and autism. Dr. Offit and co-author Jeffrey ... no data supported the association between the MMR vaccine and autism. The correlation between ...

New insights into a leading poultry disease and its risks to human health

... is leading a USDA funded project to develop a vaccine against a leading poultry disease called avian ... hopes to pursue the development of several new vaccine candidates. Their latest research results help ... ABC transporters, which may be used to develop vaccine candidates. In addition to nutrition, many other ...

Life Sciences Discovery Fund awards health research program grants

... research initiatives will focus on advancing vaccine development, improving the potential of cardiac ... depth of life sciences researchfrom accelerating vaccine development to targeting better drug delivery ... $4,727,296 Program title: Washington vaccine Alliance Program focus: To develop an ...

Ireland Cancer Center researcher finds most triple-negative breast cancers express muc-1 target

... Symposium, has paved the way for an upcoming vaccine trial for patients with early stage triple ... breast cancer cells could be a target for a novel vaccine using the patient's immune system to target and ... Institute and the Avon Foundation to begin the vaccine trial in January 2009 for women with early stage ...

UQ research targets West Nile virus and dengue fever

... could contribute to the development of a vaccine and cure for West Nile virus and Dengue fever. ... engineered viruses offer great potential as vaccine candidates as they are expected to elicit an ... anti-viral drugs and engineering similar vaccine candidates for other medically important ...

Fractional dose of scarce meningitis vaccine may be effective in outbreak control

... the standard dose of a commonly used meningitis vaccine may be as effective as using the full dose. This new finding should allow scarce vaccine resources to be stretched further, especially ... patients receiving smaller doses of a meningitis vaccine were found to be comparable to a full dose. ...

New study indicates smallpox vaccination effective for decades

... Under such circumstances, the supply of smallpox vaccine may be insufficient for universal administration. ... a smallpox bioterrorist attack, vaccinia smallpox vaccine should be used first on individuals who have not ... were included. Although the vaccinia virus vaccine was used since the late 18th century, routine ...

New type of vaccines deliver stronger and faster immune response

... A new vaccine principle is being developed by scientists at the ... save millions of lives and revolutionise current vaccine technology. The 'InVacc' platform, as it is ... invades. "We are excited to be working on the vaccine technology", says Associate Professor Jan ...

Flu shot protects kids -- even during years with a bad vaccine match

... Children who receive all recommended flu vaccine appear to be less likely to catch the respiratory ... though those years had poor matches between the vaccine and the circulating flu strains, the shots were ... which was performed as part of the CDC-funded New vaccine Surveillance Network, included 2,400 from 6 ...

Bayhill Therapeutics and the Juvenile Diabetes Research Foundation announce research collaboration

... I/II human clinical trial of BHT-3021, a DNA vaccine to reverse the immune response that causes type 1 ... is an antigen-specific immunotherapeutic DNA vaccine designed to reverse the underlying autoimmune ... Vice President, Research. "Bayhill's DNA vaccine protocol has the potential to negate the ...

Research identifies type of vaccine that holds promise in protecting against TB

... -- Researchers are one step closer to finding a vaccine that better protects against tuberculosis. An investigational vaccine for TB tested at Saint Louis University appears ... lead author of the study. The investigational vaccine is made from a weakened TB germ from one of the ...

Bird flu vaccine protects people and pets

... A single vaccine could be used to protect chickens, cats and ... issue of the Journal of General Virology . The vaccine protects birds and mammals against different flu ... researchers in the USA have discovered that a vaccine based on a bird flu virus could be used to ...

Children's National researchers develop novel anti-tumor vaccine

... WASHINGTON, DCA novel anti-tumor vaccine for neuroblastoma and melanoma developed by ... journal Cancer Immunology, Immunotherapy . The vaccine uses the tumor's own protein to induce an immune ... for a personalized approach to treatment. The vaccine and delivery system, developed in the laboratory ...