Defining DNA differences to track and tackle typhoid
... DNA sequencing technologies have been turned on typhoid
fever - a disease that kills 600,000 people each ... more successfully with the aim of eradicating typhoid
Unlike most related Salmonella ... and treat carriers, could be used to eradicate typhoid
as a disease."
There are 17 million cases ...
Details of bacterial 'injection' system revealed
... leading to bloody diarrhea and sometimes death. Similar secretion systems exist in a range of other infectious bacteria, including those that cause typhoid
fever, some types of food poisoning, and plague.
"Understanding the 3D structure of these secretion proteins is important for the design of new ...
Test of bacteria toxin delivery system could pave way for new antibiotic drugs
... effectors into attacked host cells. This process is termed a type III secretion system (TTSS). Among these pathogens are Salmonella; the cause of typhoid
fever, Yersinia; and enteropathogenic (intestinal) E. coli, which is responsible for the death of up to one million infants per year, mostly in ...
Typhoid fever led to the fall of Athens
... teeth from an ancient Greek burial pit points to typhoid
fever as the disease responsible for this ... enterica serovar Typhi, the organism that causes typhoid
fever. The results of this study point to typhoid
fever as the probable cause of the Plague of ...
Protein discovery targets antibiotic-resistant bacteria
... the organism that causes salmonellosis is related to that responsible for typhoid
fever ?a huge problem in less developed countries ?the model being developed at Queen’s could potentially be a target for treating typhoid
as well. The underlying goal is to control, if not clear, the infection. ...
New bacterium discovered -- related to cause of trench fever
... at UCSF from a patient who had been on an international vacation. The woman, who has since recovered, suffered from symptoms similar to malaria or typhoid
fever, two infections that can occur in returning travelers.
But genetic detective work revealed that she was infected with a new bacterium that ...
Malaria vaccine prompts victims' immune system to eliminate parasite from mosquitoes
... "With conjugate technology, NIH researchers have developed effective vaccines against such scourges as Haemophilus influenzae type B meningitis and typhoid
fever," said Elias A. Zerhouni, M.D., Director of the National Institutes of Health. "The experimental malaria vaccine shows great promise for ...
Researchers map spread of pathogens in the human body
... in the November issue of PLoS Biology.
The work analyses the spread and distribution of Salmonella in the body, which is a bacterium that causes typhoid
fever and food borne gastroenteritis in humans and animals, with severe medical and veterinary consequences and threats for the food industry. The ...
Patterns in genome organization may partially explain how microbial cells work
... Biology, the researchers reported large- and small-scale organizational patterns in the genomes of 135 bacteria ranging from those that cause typhoid
fever and various other human infections to organisms that enrich the nitrogen content of soil. In addition, 16 more primitive microorganisms, ...
Hurricane aftermath: Infectious disease threats from common, not exotic, diseases
... exotic diseases. These common infections can often be prevented using simple hygiene measures and a little common sense.
"Deadly diseases, such as typhoid
or cholera, are unlikely to break out after hurricanes and floods in areas where these diseases do not already naturally occur," says Ruth Berkelman, ...
Research on antibiotics receives historical recognition
... toxic to humans, and it attacked a type of bacteria resistant to penicillin. In addition to treating tuberculosis, streptomycin was effective against typhoid
fever, cholera, bubonic plague and other diseases. Among the other antibiotics isolated in Waksman's laboratory was neomycin, still used as a topical ...
Active Vaccine Prevents Mice From Developing Prion Disease
... attached to a genetically modified strain of Salmonella. This bacterium is also used in several animal vaccines and in human vaccines for cholera and typhoid
fever. Among mice vaccinated prior to prion exposure, approximately 30% remained alive and symptom-free for 500 days, according to the study. By ...
To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists
... of the leading causes of death in the United States. But then came the antibiotic revolution. Antibiotic "wonder drugs" toppled tuberculosis (TB) and typhoid
fever, controlled cholera and gonorrhea, reduced staphylococcal dysentery, and lowered the incidence of many other pandemic bacterial infections. ...