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Triglyceride in Biological News

New approach discovered to lowering triglycerides

... lab animals, supplements of lipoic acid lowered triglyceride levels up to 60 percent. If the effect were the ... , a professional journal. "The extent of triglyceride reduction was really dramatic, we didn't expect ... supplements of lipoic acid appeared to affect triglyceride levels through two pathways. After eating, lipoic ...

Cortisol and fatty liver: Researchers find cause of severe metabolic disorders

... diseases such as asthma also cause the triglyceride level in the liver to rise to dangerous levels. ... blocking the hormone's effect. As a result, the triglyceride level in the livers of the experimental animals ... their HES1 levels in the liver drops, while triglyceride levels rise. Further experiments have shown that ...

New genetic variants associated with lipid levels, risk for coronary artery disease

... in 18 genes that influence HDL, LDL and/or triglyceride levels. This list of lipid-associated genes is ... with HDL levels, one with LDL levels, three with triglyceride levels and one with both triglycerides and LDL ... with CAD. People with the gene variant for high triglyceride levels also had an increased risk for CAD, ...

People with heart disease still have trouble controlling blood lipid levels

... we have found little change in HDL-C levels and an actual increase in triglyceride levels," Wong said. "This is not good news, as these factors are important ... levels should be 40 mg or higher for men and 50 mg or higher for women. triglyceride levels should be below 150 mg. Obesity and an increasingly sedentary ...

People with diabetes may have all natural citrus supplement

... symptoms including increased blood glucose, insulin, cholesterol and triglyceride levels. Half of the animals were then given Diabetinol for 42 days. The ... showed improvements in each blood glucose, insulin, and cholesterol and triglyceride levels. Taken together, these studies suggest that Diabetinol may help ...

Scientists associate 6 new genetic variants with heart disease risk factor

... Nature Genetics, help explain some of the variability in cholesterol and triglyceride levels that arises from genes. With the potential to help predict a ... cholesterol and triglycerides and identified a new genetic signal for triglyceride levels in humans a gene called GCKR. On its own, however, this study ...

Gladstone scientists reveal key enzyme in fat absorption

... found in the intestines and plays an important part in the uptake of dietary fat by catalyzing a critical step in making triglyceride, a kind of fat. triglyceride accounts for nearly one-third of the fat eaten by people in developed countries. Researchers in the laboratory of Robert V. Farese, Jr. MD, found ...

Athletes not spared from health risks of metabolic syndrome

... a 40-inch waist and a blood pressure reading higher than 130 over 85 he ideally should undergo a blood test to see if high cholesterol, glucose and triglyceride levels, too, indicate that he might benefit from nutrition counseling and other health guidance to prevent chronic disease down the road, Buell said. ...

New gene variants present opportunities in nutrigenomics

... Tufts University School of Medicine "It suggests people can have multiple variant genes contributing to dyslipidemia, a combination of spiked LDL and triglyceride levels and extremely low HDL-cholesterol signaling cardiovascular disease risk. "It is possible there are even more variant genes contributing to ...

Key to 'curing' obesity may lie in worms that destroy their own fat: McGill researchers

... as soon as they shift into dauer they use them up within a few days. This is because they lack an enzyme that blocks the activity of a very important triglyceride lipase. Without this regulation the lipase burns up all the fat it encounters and destroys the worm's energy reserves." This discovery was a ...

The genetic heart of the lipids

... commonly used for treating high values of 'bad cholesterol', LDL. The region around NCAN gene has previously been associated with both LDL and triglyceride levels, associated with coronary heart disease. The results are part of an emerging portrait of genes determining lipid levels: a major aim is to ...

Friend or foe? How the body's clot-busting system speeds up atherosclerosis

... recently published research, Dichek and his team bred transgenic mice that were deficient in Apolipoprotein E (and therefore had high cholesterol and triglyceride readings) and whose macrophagesthe blood cells that engulf and digest germs and other cellular debrisoverproduced urokinase. They also bred mice that ...

Obesity genes revealed

... was also associated with height, total fat mass and HDL-cholesterol, but only in European American women. A different variant was associated with triglyceride levels and HDL-cholesterol in African American women." The use of flies in a study of human obesity may seem strange, but according to De Luca ...

Limiting fructose may boost weight loss, UT Southwestern researcher reports

... through the fence," Dr. Parks said. "It's a less-controlled movement of fructose through these pathways that causes it to contribute to greater triglyceride synthesis. The bottom line of this study is that fructose very quickly gets made into fat in the body." Though fructose, a monosaccharide, or ...

Genetic variant increases triglyceride levels in Asian-Americans

... of Lipid Research . In fact, all 11 subjects who carried both copies of this rare variant for apolipoprotein A-V had extremely high and dangerous triglyceride levels in their blood. Apolipoprotein A-V is a recently discovered lipid-binding protein that likely plays an important role in metabolizing ...

Study finds possible connection between marijuana abuse and stroke or heart attacks

... transport of triglycerides and delays the breakdown of triglycerides. Increases in apoC-III levels in the blood occur in parallel with increases in triglyceride levels. Even though we still don't understand how heavy MJ use might cause increases in apoC-III levels, this protein might be one of the reasons why ...

Mapping the genetic locus for triglycerides

... Researchers have mapped out a region on human chromosome 1 that contributes to genetically elevated blood triglyceride levels, a major risk factor for heart disease. Triglycerides (TG), the main form of dietary fat, continuously circulate in the blood, but if ...

Macadamia nuts can be included in heart healthy diet

... for another five weeks. The Healthy Heart diet with macadamia nuts did reduce total cholesterol, low-density lipoprotein cholesterol and triglyceride levels compared with the standard American diet. The researchers reported in the current issue of the Journal of Nutrition, that the macadamia nuts ...

Oatmeal's health claims strongly reaffirmed, science shows

... lipoprotein (LDL, the "bad" cholesterol) is reduced without adverse effects on high-density lipoprotein cholesterol (HDL, the "good" cholesterol), or triglyceride concentrations. "Whole-grain products like oatmeal are among some of the best foods one can eat to improve cholesterol levels, in addition to other ...

Mom's obesity during conception phase may set the stage for offspring's obesity risk

... and other factors were analyzed for 130 days. At day 130 additional samples were taken and analyzed, to include organ weights, glucose and triglyceride levels, fat cell size, body composition and hormones. Key Findings The researchers found the following: at birth, the weight of the ...

Human hormone blocker found to help prevent obesity and diabetes: study

... to impaired insulin sensitivity and glucose intolerance by 10 days. Fat (adipose) tissue deposits were increased as were circulating cholesterol and triglyceride concentration levels. (Pro3)GIP was able to counter many of the detrimental effects of high fat diet on body weight and indices of glucose ...

Eating competence may lower risk of heart disease

... have levels greater than that for triglyceride. Lohse says that rather than only providing people with dietary information to lower their LDL or triglyceride levels, it might be more prudent to train people in becoming eating competent. She, however, cautions that the results offer only a snapshot in time ...

Link found between immune system and high plasma lipid levels

... could keep mice, and possibly humans, from developing high cholesterol and triglyceride levels, a key risk factor for coronary heart disease. "Besides ... lymphotoxin (LT) on T cells significantly impacted the cholesterol and triglyceride levels. When T cells expressing LIGHT were introduced into the mice, ...

Gene linked to rare disease activates fat breakdown

... Austria, now reports that CGI-58 boosts the activity of so-called adipose triglyceride lipase (ATGL) up to 20-fold. "We knew that the enzyme responsible for ... having the CDS mutation restores lipid breakdown and reverses the abnormal triglyceride accumulation typical of patients with the lipid storage disease. "These ...

Hawaiian treasure, macadamia nuts good for the heart

... for another five weeks. The Healthy Heart diet with macadamia nuts did reduce total cholesterol, low-density lipoprotein cholesterol and triglyceride levels compared with the standard American diet. "We observed a reduction in LDL similar to that seen with other tree nuts like walnuts and ...

One-third of adults with diabetes still don't know they have it

... Alaska Native, Asian American, Pacific Islander) have high blood pressure: 140/90 mm/Hg or higher have an HDL cholesterol less than 35 mg/dL or a triglyceride level 250 mg/dL or higher have had diabetes that developed during pregnancy (gestational diabetes) or have given birth to a baby weighing more than ...

Baby's genes affect mom's cholesterol levels

... of triglycerides and cholesterol in the general population. They found that when these polymorphisms were present in the babies, their mothers' triglyceride and cholesterol levels were influenced to the same extent that they would be if the polymorphisms were present in the mothers. However, when both the ...

UCSD study clarifies insulin's role in blocking release of energy in patients with type II diabetes

... is released. But in people with Type II diabetes, the hormonal balance has been thrown off, because the body continues to produce and store more triglyceride instead of breaking down the fat as released energy. “Somehow, insulin knows how to specifically block catecholamine-induced PKA, but not other ...

Excess liver gene protects against high-fat diet

... disease. When fed normal mouse chow, mice with a greater than average number of the receptors exhibited a rise in blood cholesterol and triglyceride levels. In contrast, altered mice fed a high-fat, Western diet showed improvements in blood lipid levels and protection from atherosclerosis. ...
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