Holding breath for several minutes elevates marker for brain damage

... the appearance of the protein, S100B, was transient and leaves open the question of whether lengthy ... In addition, the elevation of S100B was more transient in the divers, compared to people who suffered ... in 24 hours in brain-injured patients. The transient nature of the increase in S100B among the divers ...

AGU journal highlights -- Sept. 3, 2008

... http://dx.doi.org/10.1029/2008GL034574 5. transient currents after lightning flashes Within the ... of the GEC. After this fast process, a slow transient stage occurs, caused by redistribution of charge in the atmosphere. Noting that contributions of transient currents to the GEC are poorly understood, Mareev ...

Who's afraid of the big, bad wolf? Coyotes

... that, with coyotes, theres safety in numbers; transient coyotes without packs were more likely to fall prey to wolves, with 56 percent of transient coyote mortality being attributable to wolves. Also, transient coyotes in wolf-abundant sites were 117 percent ...

ExcellGene SA first company to offer contract manufacturing in 250 Liter OrbShake bioreactor

... be it our TubeSpin system for high-throughput process development or our transient gene expression technology platform with yields well above 1 gram per ... production services, based both on stable cell lines and on large-scale transient gene expression. The company is located in Monthey, Switzerland.  For ...

Herpes virus: To vaccinate or not to vaccinate

... in the form of letters to the editor regarding the potential benefits of a transient protective effect. The letters will be published concurrently with ... vaccinated individuals." In response, Dr. Blackman argues that possible transient protective effects did not outweigh the already recognized pathological ...

Healing wounds with lasers, vehicles that drive themselves, other cutting-edge optics

... it enables the recording of very fast phenomena. As the world's fastest light deflector, it can be used as a picosecond oscilloscope or for observing transient events like the miniature fusion reaction that occurs at the National Ignition Facility. Presentation CThW1; Thursday, June 4, 2:30 3 p.m. ...

ExcellGene and Khner achieved milestone in development of novel 250 Liter mammalian cell culture bioreactors

... scalable manufacturing under cGMP. Additionally, the company provides protein production services, based both on stable cell lines and on large-scale transient gene expression. The company is located in Monthey, Switzerland.  For additional information, please visit http://www.excellgene.com or ...

Journal of General Physiology explores mysteries of TRP channels in latest Perspectives series

... Despite the large body of literature on transient receptor potential (TRP) channelsion channels that are directly involved in vision, taste, hearing, touch, olfaction, and other sensesvery little is ...

Earth's highest known microbial systems fueled by volcanic gases

... of bacteria living on the slopes of Socompa in extremely dry soils not associated with fumaroles. The bacteria detected in such dry soils may be transient life transported and deposited by wind in the extreme environment of Socompa, with some organisms surviving to bloom during periodic pulses of water ...

Molecule that suppresses immune response under study in type 1 diabetes

... mouse that develops diabetes. Eighty percent of the female mice get diabetes by age 12 to 15 weeks. MCG researchers suspect it's because they have a transient defect in their dendritic cells that hurts IDO expression. Dendritic cells, which can express IDO, show antigens to the T-cells. A Journal of ...

A crystal clear view of chalk formation

... the crystal is already recognizable. If the clusters then group together into increasingly larger aggregates, this arrangement can remain in place. A transient amorphous form, that is, a non-crystalline solid, is initially created, which then changes into a crystal. Easier for organisms to intervene ...

Growth of new brain cells requires 'epigenetic' switch

... marks in the cell's genetic material. "How is it that when you see someone you met ten years ago, you still recognize them? How do these transient events become long lasting in the brain, and what potential role does the birth of new neurons play in making these memories?" says Hongjun Song, ...

Repeat C-section before 39 weeks raises risk of neonatal illness

... an infant who was delivered at 37 weeks later died or was diagnosed with a number of conditions, including respiratory distress syndrome and/or transient tachypnea of the newborn, newborn sepsis, seizures, necrotizing entercolitis, hypoxic ischemic encephalopathy, required ventilator support within 24 ...

New technique is quantum leap forward in understanding proteins

... another leader of the project from Scripps Research, says the process is so difficult with x-ray crystallography that it only rarely works for transient interactions. Another available means for studying protein interactions is a statistical method known as covariance, and the Scripps Research-UCSD ...

Moving new technologies from the lab to the marketplace

... as semiconductor manufacturing, opto-electronics, life sciences and material handling. This year, he received two more awards -- one for his low transient pulse technique for ultrasound imaging to detect and monitor bone fractures, and another for broadening the application base of the SmartPin, a new ...

NIST awards $24M in grants for new research facilities

... areas include the application of atomically resolved microscopy to operating nanoscale devices to observe dynamic processes and extremely rapid transient events at the nanoscale; quantum nanomechanics, an emerging discipline focused on the measurement and control of mechanical properties of ...

Drops in blood oxygen levels may be key to sudden death in some epilepsy patients

... patients with chronic, recurrent, unprovoked seizures. They compared patients with severe convulsive seizures to those with milder symptoms like transient confusion, lip smacking and head turning. One-third of all seizures were associated with drops in blood-oxygen levels below 90 percent. Seyal said ...

Early-stage gene transcription creates access to DNA

... gene. The group discovered that the process of transcribing non-coding RNAs is required for the eventual production of the protein-encoding RNA. The transient synthesis of these non-coding RNAs serves to unfurl the tightly wound DNA, essentially loosening the structure to allow for gene expression. "This ...

Conaway Lab identifies novel mechanism for regulation of gene expression

... "touch and go" mechanism, in which proteasomes interact transiently with Uch37. "Our findings suggest that activation of INO80-associated Uch37 by transient association of proteasomes with the INO80 complex could be one way proteasomes help to regulate gene expression," said Tingting Yao, Ph.D., ...

October 2008 Biology of Reproduction highlights

... in the mouse. These authors used a conditional knockout (CKO) approach to delete Dicer1 in the germline. Because the CKO mice exhibited transient fertility, an elegant reporter strategy was used to demonstrate that elongated spermatids present in the CKO testes did express the Cre recombinase; ...

Study reveals how viruses collectively decide the fate of a bacterial cell

... lysis," explained Weitz. "In our model, when multiple viruses infect a given cell, the overall production of regulatory proteins increases. This transient increase is reinforced by a positive feedback loop in the latency pathway, permitting even higher production of lysogenic proteins, and ultimately ...

Smoke smudges Mexico City's air, chemists identify sources

... author on both papers. "Our instrument brings in a new level of precision by allowing us to identify high levels of specific pollutants that occur in transient peaks. A harmful type that is present in high amounts for just a few hours might be overlooked in a sample collected over the course of an entire day ...

Scientists reveal the key mechanisms for affinity between transient binding proteins

... peptide structures. Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have performed the first computational analysis of transient interactions between proteins in order to reveal what determines their recognition as ideal partners and have unveiled part of the molecular ...

New paradigm for cell-specific gene delivery

... of these proliferative diseases of the vasculature. It can be highly cell-specific, mimic or restore normal in vivo function, and can be permanent or transient depending on vector design. Currently, a number of gene delivery systems for use on the arterial wall are being studied, but as yet their low ...

USGS science picks -- leads, feeds and story seeds

... Monograph by the USGS and Alaska Department of Fish and Game, half of the wolves harvested in the central Brooks Range of Alaska were probably transient wolves, including dispersers from local packs and distant migrants. The authors also examined other North American wolf studies and found that wolf ...

Mouse model developed at UT Southwestern mimics hyperglycemia, aids in diabetes research

... women who have never had diabetes develop hyperglycemia. Gestational diabetes usually disappears after pregnancy, but it is not clear whether these transient bouts of elevated glucose can cause permanent damage in the vasculature that persists even after normal glucose levels have been restored. Dr. ...

Even low levels of air pollution may pose stroke risk

... health problems when inhaled. These particles can be man-made or from natural sources. In the study, researchers identified ischemic strokes and transient ischemic attacks (TIA), sometimes called mini strokes but that often lead to a stroke later. Ischemic attacks are caused by a blockage of blood flow ...

Body image program reduces onset of obesity and eating disorders

... This program simply teaches youth to balance their energy intake with their energy needs, and to do so on a permanent basis, rather than on the transient basis which is more typical of diets. College-age women in Eugene/Springfield are participating in this study. The eating disorder prevention ...

New research shows no link between aromatase inhibitors and cardiovascular problems

... no significant differences were seen in total cholesterol levels between different AIs. In a second trial (MAP.1) letrozole was associated with a transient decrease in cholesterol levels. In trials that compared AIs with tamoxifen, increases were seen in heart-related problems, but in another trial ...

Fast AFM probes measure multiple properties of biomolecules or materials simultaneously

... the material and how stiff and sticky it is. An output signal is generated only when there is an interaction force on the probe. In other words, transient interaction forces can be measured during each tap of the tip with high resolution and without any background signal. In the February 27 issue of ...

Slow slip and slide dynamics

... able to compile a good record that will help us to better understand the earthquake process. The team plans to create computer models of both the transient motion on the fault plane, as well as the locking patterns before and after the events in an effort to determine if the occurrence of a slow slip ...

Media highlights in the March 1 issue of Biophysical Journal

... as they execute and regulate various complex processes. For a complex cellular activity like migration, which is characterized by highly localized, transient component processes, the need is for high resolution spatial maps is essential. The currently available techniques only measure protein concentration ...

Researchers reveal HIV peptide's possible pathway into the cell

... surface it is directly attached to, it reaches through the membrane to grab negatively charged groups in the molecules on the other side, opening a transient hole in the cell. "What we saw in our computer calculations wasn't at all what we expected to see when we began," said co-lead author and Senior ...

Biophysical Society announces 2008 International Travel Awards

... of Glasgow, United Kingdom, K201 Inhibits Diastolic Ca2+ Release And Contractions in Isolated Rat Cardiomyocytes Without Increasing Subsequent transient Amplitude. Yingang Feng, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Solution Structure and DNA-binding Surface of a ...

Damon Runyon Cancer Research Foundation awards prestigious fellowships to 17 top young investigators

... his sponsor David J. Julius, PhD, at the University of California, San Francisco, California, is investigating the structure and function of sensory transient receptor potential (TRP) channels for better management of cancer-related pain. Alexandra M. Deaconescu, PhD , with her sponsor Nikolaus ...

'Runner's high' may also strengthen hearts

... suggesting that opioids are responsible for some of the cardiac benefits of exercise. The UI team also showed that exercise was associated with transient increases in expression of several opioid system genes in heart muscle, and changes in expression of other genes that are involved in inflammation ...

American Chemical Society's Weekly PressPac -- Sept. 26, 2007

... passengers daily. They exposed live mice and cultured mice cells to the dust over a 24-hour period. Exposure to the subway dust triggered transient lung inflammation in the mice and increased levels of several substances produced by the immune system that might cause tissue damage. Some but not ...

Mice with a migraine show signs of brain damage

... have found evidence that the headaches may also be acting like tiny transient strokes, leaving parts of the brain starved for oxygen and altering the ... exactly like the damage that occurs to the brain from repeated TIAs, or transient ischemic attacks,?said Takano. “It’s long been known that patients having ...

Scientists see DNA get 'sunburned' for the first time

... as skin cancer. For this study, the chemists used a technique called transient absorption to observe the DNA damage. transient absorption is based on the idea that molecules absorb light at specific ...