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Thyroid in Biological News

Specific genetic cause of fetal alcohol-related developmental disorders found

... with the genetic processes that control thyroid hormone levels in the fetal brain, a new animal ... during pregnancy decreases the level of maternal thyroid hormones and, therefore, fetal thyroid hormones. "Specific concentrations ...

First comprehensive guidelines for managing medullary thyroid carcinoma published in Thyroid journal

... and monitoring of patients with Medullary thyroid Carcinoma (MTC), an uncommon and challenging form of thyroid cancer, have been developed by the American thyroid Association and published online ahead of print ...

Skip this cocktail party

... which are neurotoxicants known to disrupt the thyroid hormone system. The study also quantifies ... fluid in mammals. This protein plays a role in thyroid hormone transport throughout the brain, though its exact role is not known. thyroid hormone plays a key role in the development of ...

Smoking during pregnancy may impair thyroid function of mom and fetus

... harmful changes in both maternal and fetal thyroid function, according to a new study accepted for ... "We studied the influence of cigarette smoking on thyroid function of two groups of women at different ... is associated with changes in the mothers' thyroid hormone levels." Optimal ...

Researchers discover atomic bomb effect results in adult-onset thyroid cancer

... in some survivors who later developed papillary thyroid cancer as adults, according to Japanese ... kinase-signaling pathway may be sufficient for thyroid cell transformation and tumor development," said ... that have been shown to have an increase in thyroid cancer, and that children exposed to radioactive ...

Presence of gene mutation helps guide thyroid cancer treatment

... useful in predicting the level of aggression of thyroid cancer and help guide treatment options and ... frequently occurs in the most common type of thyroid cancer, conventional papillary thyroid cancer or PTC, but this is the largest study to ...

New molecular regulators of hyperthyroidism and goiter

... The thyroid gland has an important role in determining how much energy the body burns. thyroid gland functions are regulated by a hormone known ... TSH-induced signals and therefore in regulating thyroid gland function. This makes Gq and G11 potential ...

JCI table of contents: Aug. 9, 2007

... regulators of hyperthyroidism and goiter The thyroid gland has an important role in determining how much energy the body burns. thyroid gland functions are regulated by a hormone known ... TSH-induced signals and therefore in regulating thyroid gland function. This makes Gq and G11 potential ...

Carnegie's Donald Brown receives lifetime achievement award from Society for Developmental Biology

... that occur when a tadpole turns into a frog are controlled entirely by thyroid hormone. By studying its role in amphibian metamorphosis, Brown and ... to analyze the complexities of the hormone-gene interactions. He used thyroid hormone-induced metamorphosis in the frog Xenopus laevis to identify genes ...

Galloping and breathing at high speed

... or undergo laryngeal transplant. The disorder can be a complication of thyroid surgery in people who have had thyroidectomies, usually to remove cancer from the thyroid gland. In addition to the paralysis, it can effect speech, voice and ...

Looking for the Founatain of Youth? Cut your calories, research suggests

... in rodents, one popular hypothesis is that it slows aging by decreasing a thyroid hormone, triiodothyronine (T3), which then slows metabolism and tissue ... in the calorie restriction group also experienced lower levels of the thyroid hormone. Although a long-term study is still needed to determine if ...

Study links cat disease to flame retardants in furniture and to pet food

... WASHINGTON, Aug. 15, 2007 A mysterious epidemic of thyroid disease among pet cats in the United States may be linked to exposure to ... agents, cats may well be at increased risk for developing thyroid effects. The danger of contracting feline hyperthyroidism might be ...

NOAA report calls flame retardants concern to US coastal ecosystems

... to evidence that exposure to PBDEs may produce detrimental health effects in animals, including humans. Toxicological studies indicate that liver, thyroid and neurobehavioral development may be impaired by exposure to PBDEs. They are known to pass from mother to infant in breast milk. Similar in ...

17th Annual Congress on Women's Health convenes

... Autoimmune Related Diseases Association, American College of Physicians-Virginia Chapter, American Heart Association's Go Red for Women, American thyroid Association, Arthritis Foundation, National Stroke Association, National Women's Health Resource Center, The North American Menopause Society, and ...

How eating fruit and vegetables can improve cancer patients' response to chemotherapy

... tea and wine). It has been shown by researchers to have growth inhibitory properties in several cancer lines, including breast, colon, skin, thyroid and leukemia cells. It has also been shown to inhibit pancreatic cancer cell proliferation. "Our study advocates the inclusion of vegetables and ...

6 environmental research studies reveal critical health risks from plastic

... (phthalates used in PVC plastic), mimic the action of the sex hormone estrogen (bisphenol A or BPA used in polycarbonate plastic), and interfere with thyroid hormone (brominated flame retardants or PBDEs used in many types of plastic). Two articles report very similar changes in male reproductive ...

Media invitation: 20th EORTC-NCI-ACR Symposium on Molecular Targets and Cancer Therapeutics

... response to treatment in advanced colorectal cancer; New drug shows impressive activity in patients with advanced disease, including medullary thyroid cancer. Phase III trials planned; Researchers discover that a genetic mutation makes metastatic colorectal cancer patients resistant to anti-EGFR ...

American Chemical Society's Weekly PressPac -- June 25, 2008

... perchlorate to speed up the fuel-burning process. But some studies have linked perchlorate, which can accumulate in the soil, air and water, to thyroid damage. Pyrotechnics also contain color-producing heavy metals, such as barium and copper, which have also been linked to toxic effects. ...

Experts tackle shipment issues for beneficial radiation sources

... of timely, efficient and safe international shipments to hospitals and industries. Some radioisotopes, such as iodine-123 - used for heart and thyroid imaging - have a half-life of only hours. Consequently, any interruption to their delivery can threaten the medical care of patients. According to ...

Acoustics World Wide press room now open

... but across their mouth cavities. Catherine Carr, University of Maryland http://www.acoustics.org/press/154th/carr.html BETTER DETECTION OF thyroid CANCER Harder tissues produce a significantly different acoustic field than softer tissues, and a novel, non-invasive imaging technique called ...

Dartmouth researchers show effects of low dose arsenic on development

... whether arsenic can also disrupt the activity of two hormone receptors that are involved in normal development - the retinoic acid receptor and the thyroid hormone receptor, two important members of the larger nuclear hormone receptor family. While the researchers studied the impact on frog development, ...

Study reveals 2 genes linked to disabling arthritis

... The researchers also validated the association of two genes implicated in Graves disease, an autoimmune condition that causes overactivity of the thyroid gland. Principal investigator and corresponding author Lon Cardon, Ph.D., and colleagues in the U.K.-based Wellcome Trust Case Control Consortium ...

SRMs track fire retardants in humans and environment

... are limited, the U.S. Environmental Protection Agency (EPA) cites animal tests as evidence that PBDEs are neurodevelopmental toxins, disruptors of thyroid functions, and liver toxins. The doses used in animal studies were slightly higher than PBDE levels found in some people in the United States. ...

How appetite-stimulating brain cells work overtime during fasting

... The researchers revealed a link between active thyroid hormone in the brain and increases in an ... lacking either UCP2 or an enzyme that stimulates thyroid hormone's production ate less than normal after a ... in peripheral body tissues, Diano added. thyroid hormones are known to play major roles during ...

Longer-lived rodents have lower levels of thyroid hormone

... The thyroid may play an important role in longevity, with ... rodents showing significantly lower levels of a thyroid hormone that speeds metabolism, a new study has ... said Mario Pinto, the study's lead author. The thyroid releases hormones that regulate metabolic rate. ...

Bitter taste identifies poisons in foods

... act as anti-thyroid compounds. The thyroid converts iodine into thyroid hormones, which are essential for protein ... increasing risk for goiter and altering levels of thyroid hormones. The ability to detect and avoid ...

Radioactive scorpion venom for fighting cancer

... this is not tremendously high compared to a thyroid cancer treatment, in which patients receive up to ... iodine prior to the therapy to block the thyroid uptake of I-131. When the patient returns ... to those from a family member receiving standard thyroid cancer therapy. Jackson is encouraged by the ...

Role of microRNA identified in thyroid cancer

... of RNA is enough to clearly distinguish cancerous thyroid tissue from otherwise normal tissue, scientists ... inherit a predisposition to developing papillary thyroid cancer (PTC), the most common form of thyroid cancer, representing about 80 percent of all ...

Chernobyl: The true scale of the accident

... doses, and for the thousands more stricken with thyroid cancer. By and large, however, we have not found ... the new findings. * About 4,000 cases of thyroid cancer, mainly in children and adolescents at the ... contamination and at least nine children died of thyroid cancer; however the survival rate among such ...

UCLA study uncovers clues for why Graves' disease attacks the eyes

... an antibody that other people do not. Not recognizing the patient’s thyroid as "self," the antibody mistakenly mounts an attack against the organ, ... with the T-cells and slow down the disease. In Graves?disease, the thyroid gland goes into overdrive, producing excess levels of hormone that attack ...

In drug design, a loose fit may be best bet

... a chain of events throughout the body, including the stimulation of the thyroid gland. As with many of the body's hormones, cells recognize TRH using a ... of the paper. "At first glance, a cellular process that affects the thyroid gland may not seem especially meaningful to the study of communication ...

Protein amplification in melanoma is possible drug target

... and also predispose people to autoimmunity, particularly affecting the thyroid gland and resulting in thyroid hormone insufficiency. Finally, people with CVID are susceptible to B-cell ...

Gene for immune deficiency syndromes found

... and also predispose people to autoimmunity, particularly affecting the thyroid gland and resulting in thyroid hormone insufficiency. Finally, people with CVID are susceptible to B-cell ...

Enzyme delivered in smaller package protects cells from radiation damage

... increasing concern that such high doses of radiation may have long-term negative effects on healthy tissues and organs, such as the kidney, liver and thyroid gland. Based on previous studies showing that intravenous gene therapy delivery of the enzyme manganese superoxide dismutase (MnSOD) could ...

Investigating the measles virus as a tool to kill multiple myeloma

... measles virus which was engineered to carry an additional gene that codes for the sodium iodide symporter (NIS) protein. NIS is produced by the thyroid where it attracts and concentrates iodine. This characteristic of the NIS protein can be exploited as a target in cancer therapy because it can ...

Bacteria research offers hope for new vaccine against meningococci

... system, but then they resurge, this time with alterations in the surface protein. What’s more, we discovered that the bacteria aggregate in the thyroid and can impact hormone production during the infection,?says Ann-Beth Jonsson. The study also shows that bacteria that lack a certain adhesin ...

Microbes transform 'safest' PBDEs into more harmful compounds

... more toxic when released into the environment." In laboratory animals, high blood levels of PBDE are associated with cancer, lowered immunity, thyroid problems, and learning and memory difficulties. Although PBDE levels in people haven’t reached the levels of laboratory animals, Alvarez-Cohen says ...

Memory loss affects more of the brain than previously thought

... and your family, you should undergo comprehensive testing by a physician, as memory loss can be caused by many underlying factors such as depression, thyroid problems and stress, and doesn't necessarily indicate early AD," Dr. Petrella said. ...

Molecular force field helps cancer cells defend against attack

... is tied to the growth of channels in the lymph system that serve as cellular superhighways for cancer spread and is found in breast, colon and thyroid tumors. Cance and colleagues were the first to pull FAK out of human tumors and to show that human cancers make the molecule in large quantities. ...
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