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Structural in Biological News

'Normal' cells far from cancer give nanosignals of trouble

... under the microscope, share very similar structural abnormalities on the nanoscale level. The ... by measuring the increase in disorder -- the structural variations -- within the cell. PWS quantifies the ... without. The cancer cells showed an increase in structural disorder on the nanoscale. For each organ, the ...

Structural biology scores with protein snapshot

... investigators in the Vanderbilt Center for structural Biology have used nuclear magnetic resonance ... structure using both NMR and a complementary structural approach, X-ray crystallography. DAGK may be a ... because of their work with DAGK, are now pursuing structural studies of misfolded membrane proteins that cause ...

Laughing hyenas, wailing levees, the sound of cheese and blaring bagpipes

... Guarino and his team work on a full-scale structural model made of steel beams and girders connected ... and retraces its steps to the first detector, any structural imperfections show up as a disturbance in the ... work in buried pipes. The talk "Detection of structural faults in pipelines with time reversal" (3aSA7) ...

6 young ASU faculty earn NSF Career awards

... provide higher strength per weight than other structural materials, such as metals. The improved ... "We are the first to show you can improve the structural performance of composite materials by using a ... to understand the causes of these massive structural rearrangements to uncover the coupling between ...

Distinguishing single cells with nothing but light

... a microscopy system that gathers chemical and structural information by combining two previously distinct ... way to get a fingerprint from the molecule." structural information is simultaneously gathered by ... original course. Together the chemical and structural information provide the data needed to classify ...

CSHL researchers pinpoint structure-building role for 2 non-coding RNAs

... within the cell's nucleus. RNAs as structural components Unlike its counterparts in simple ... RNA molecule that gives paraspeckles their structural integrity was never found." Spector, who is ... the nucleus. MENε and MENβ are structural organizers The paraspeckles were larger in ...

Fluorescent proteins illuminating biomedical research

... Ph.D., associate professor of anatomy & structural biology at Einstein, and a member of the ... Ph.D., co-chair and professor of anatomy and structural biology and co-director of the Gruss Lipper ... of developmental & molecular biology, anatomy & structural biology, and medicine, Dr. Verkhusha employed the ...

Molecules in the spotlight

... systems. It allows a better understanding of the structural evolution of molecules during a chemical ... in hemoproteins (haemoglobin, myoglobin). structural evolution It is possible to follow a cat ... researchers were able to follow in real time a structural change of the molecule in 150 femtoseconds. This ...

New insight into the controls on a go-to enzyme

... fellow in Green's laboratory, performed X-ray structural analysis on such a protein crystal that consisted ... the calpastatin molecule attached to calpain. The structural picture obtained of the two proteins clutched ... more effective regulator. The researchers' structural information also showed how calpain changes its ...

Urban trees enhance water infiltration

... stormwater detention reservoir constructed of structural soil. structural soils are engineered mixes designed to both ... with unplanted controls. In the experiment, a structural soil reservoir (CUSoil, Amereq Corp., New York) ...

Einstein researchers develop a new way to study how breast cancer spreads

... Jeffrey Segall, Ph.D., professor of anatomy and structural biology. "Mapping the fate of tumor cells in ... Ph.D., co-chair and professor of anatomy and structural biology and co-director of the Gruss Lipper ... Ph.D., associate professor of anatomy and structural biology, and Jeffrey Wyckoff, M.F.A., B.S., ...

Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida

... methods. The session "Musical Acoustics and structural Acoustics and Vibration: structural Vibrations in Musical Instruments" (3aMU) takes ... group is exploring ways to use the delay as a structural musical element. Once the musicians become ...

MIT: Mending broken hearts with tissue engineering

... the first to be explicitly designed to match the structural and mechanical properties of native heart tissue. ... Each scaffold could be tailor-made with specific structural and mechanical properties. "We're already on the ... "previous scaffolds did not necessarily possess structural or mechanical properties consistent with the ...

How we see objects in depth: The brain's code for 3-D structure

... of surface fragments, something like a structural drawing. Individual neurons are tuned to respond ... structure, and that may be due to this clear structural representation in the brain," explains Charles E. ... experiment can identify artistically powerful structural motifs, the next step would be to study how those ...

Structures of important plant viruses determined

... from viruses and other forms of damage. The structural information may also benefit scientists ... before these studies," said Gerald Stubbs, a structural biologist at Vanderbilt University and lead ... the details of their structures." For example, structural information could help scientists design ...

Life isn't 2-D, so why should our encyclopedias be?

... linking written information and three-dimensional structural information. The wiki web resource, first ... explained in the text. This makes the complex structural information readily accessible and comprehensible, even to people who are not structural biologists. The resource was developed at the ...

Structural biology spin-out tackles major diseases

... A spin out company from basic structural biology, Asterion Ltd., has led to new technology ... developed by Asterion Ltd. is based on basic structural biology work that has provided us with the ... that prevent them from being degraded. The basic structural biology work we have done in the past means that ...

N.Y. research team discovers how antidepressants and cocaine interact with brain cell targets

... University Medical Center, stabilized different structural states of the neurotransmitter-sodium-symporter ... had allowed the identification of only one structural form of the molecule, but our experiments and ... Molecular understanding at this level of structural and dynamic detail is rare in the world of drug ...

Latest advances in interventional cardiology for congenital heart disease presented

... of interventional therapies for congenital and structural heart disease will gather in Las Vegas July 20-23 ... director of the Rush Center for Congenital and structural Heart Disease, will perform closure of an atrial ... led by Ilbawi, a breakout session about adult structural heart disease moderated by Dr. Cliff Kavinsky, ...

News tips from the Journal of Neuroscience

... Christian Bchel, and Arne May Learning-induced structural changes in the human brain were previously ... have now extended this research to show that such structural changes also occur in older (50- to 67-year-old) ... results indicate that human brains retain some structural plasticity as they age. 3. Preventing ...

Bamboo instant houses will soon shelter Sichuan quake victims

... with more to come. Yan Xiao, an expert in structural design and retrofit in the Viterbi School's Sonny ... with bamboo-based materials for highly demanding structural uses in China's Hunan province, and recently ... foot) house in about 4 hours. The majority of the structural materials used are processed bamboo veneer ...

Leemor Joshua-Tor, PhD, CSHL biologist and WSBS dean, is named an HHMI Investigator

... (HHMI) Investigator. Dr. Joshua-Tor, a structural biologist whose work is known and respected ... for Slicer activity, and shedding light on a structural feature of the protein -- a groove in its ... her discovery of Slicer, Dr. Joshua-Tor has used structural biology and molecular biology tools to determine ...

Getting wise to the influenza virus' tricks

... machinery of infected cells has been laid bare by structural biologists at the European Molecular Biology ... Grenoble, France. In the current issue of Nature structural and Molecular Biology they publish a ... is similar to other cap-binding proteins, its structural details are distinct. Collaborators at the Centro ...

For the paper trail of life on Mars or other planets, find cellulose

... resilient substance best-known as the major structural component of plant matter. It is one of the most ... carbon-based life forms into cellulose as a structural molecule. Cellulose is like the bacterias house, ... them. Plants adopted cellulose as their structural entity, and insects changed cellulose slightly to ...

CSHL scientists part of team that discovers role of rare gene mutations in schizophrenia

... something we didnt know before: that rare structural mutations in genes, while present in both healthy ... results are powerful because they link specific structural variation in genes with specific functions known ... should focus on methods that allow detection of structural mutations across the genome in affected ...

Protein's strength lies in h-bond cooperation

... lies in the specific geometric configuration of structural proteins, which have small clusters of weak ... bind together stacks of short beta strands in a structural protein rupture simultaneously rather than ... the cooperative nature of the hydrogen bonds. structural proteins contain a preponderance of beta-sheets, ...

University of Chicago launches research program in catastrophic deformation

... that occur in processes where small-scale structural rearrangements result in rapid and far-reaching ... of behavior in the cystoskeleton, which provides structural support for cells. Precise new measurements may yield a better understanding of the cytoskeleton's structural rearrangements. "At long timescales, there is ...

Biophysical Society announces 2008 International Travel Awards

... 3D Structure of the Unliganded gp120 Based on structural Homology and Molecular Dynamics Symulations. ... Petrpolis, Brazil, Temperature Effects on structural Properties of Active Sites: Molecular Dynamics ... University of Cologne, Germany, Cw-EPR Based structural and Functional Characterization of a Molecular ...

Unique porous copper structure enables new generation of military micro-detonators

... chips. An ability to tailor the porosity and structural integrity of the explosive precursor material is ... channel sizes as small as a few microns with structural components that have nanoscale pores. Based on ... will explode. We are now able to link structural characteristics to performance, Nadler noted. We ...

Purdue researchers obtain a snapshot clarifying how materials enter cells

... said Chen, who also is a member of Purdue's structural biology group within the College of Science. ... The collaboration between Chen and Davidson, a structural biologist and a biochemist, was the key to ... to crystallize and solve the structure." While structural biologists attempt to obtain images of a protein ...

Brilliant perspectives

... X-ray light in Hamburg. On occasion of the structural completion of the building, German Research ... X-ray laser XFEL, a worldwide unique centre of structural research is being created at DESY. One ... production parts for signs of fatigue. Above all, structural and dynamical analyses of nanoparticles or ...

Proteins pack tighter in crowded native state

... cell is so tightly packed it may increase the structural content of proteins by as much as 25 percent, ... evidence -- both in silico and in vitro -- for structural effects on proteins in the native state." To ... Stagg and Wittung-Stafshede then probed how the structural content as well as the thermal stability of ...

New approach builds better proteins inside a computer

... with remarkable accuracy. Their methods will help structural biologists overcome a challenge commonly known as ... The paper represents a real breakthrough, wrote structural biologist Eleanor Dodson in a News & Views ... And in the future, this method might provide structural information about intractable molecules that are ...

UD plant biologists uncover top wetland plant's hidden weapon

... that the substance literally disintegrates the structural protein in the roots of neighboring plants, thus ... toxin works, Bais said, by targeting tubulin, the structural protein that helps plant roots to maintain their ... starts to disintegrate. Within 20 minutes, the structural material is completely gone. When the roots ...

Using nanotubes to detect and repair cracks in aircraft wings, other structures

... the performance, reliability, and safety of structural components in a variety of engineering systems, ... enough to prevent a complete, or catastrophic, structural failure. This method is an effective way to ... microcracks, as well as a less-common form of structural damage called delamination. Whats novel about ...

Joint research into an enzyme that causes genetic diseases

... release is available in Spanish . Researchers from CIC bioGUNE's structural Biology Unit and Columbia University (New York) have conducted a joint ... models is the correct one. Mikel Valle, a researcher from CIC bioGUNE's structural Biology Unit explains that This is the start of a highly ambitious study ...

University has grand designs to build a house of straw

... be made using 'ModCell' - pre-fabricated panels consisting of a wooden structural frame infilled with straw bales or hemp and rendered with a breathable ... system. ModCell is the creation of White Design in Bristol and Integral structural Design in Bath. Other partners on the research project are Agrifibre ...

Munich researchers discover new target for tailored antibiotics

... Universitt Mnchen, and their research team have described in detail the structural basis for just such a reaction step. The cells of virtually all life ... may spell doom for those bacteria. The TUM researchers have unraveled the structural basis of the terminal step in bacterial isoprene synthesis. The crucial ...

DNA template could explain evolutionary shifts

... two a process known as mitosis. Copy number variation involves structural changes in the human genome that result in the deletion of genes or parts ... wrote, "We propose that FoSTeS/MMBIR may be a key mechanism for generating structural variation, particularly nonrecurrent CNV (copy number variation), of the ...

NIH funds $9.5 million for research on HIV and the human innate immune system

... and tap the expertise of researchers in innate immunity, defensin biology, structural chemistry, HIV immunology, dermatology, oral medicine and genetics. ... and tap the expertise of researchers in innate immunity, defensin biology, structural chemistry, HIV immunology, dermatology, oral medicine and genetics. ...
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