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Spine in Biological News

International prize for Nottingham spine research

... categories of the annual ISSLS Prize for Lumbar spine Research. Awarded by the International Society for the Study of the Lumbar spine (ISSLS), the accolade is designed to encourage ... discs the soft discs in between the bones of the spine that allow it to bend and flex which can be ...

Oh, my aching back: Give me a shot of ozone

... than for the diskectomy," said Murphy. "The spine is a stunningly beautiful piece of engineering, or, as our engineers say, the spine is like a complex electromechanical system. And ... works. The bones (vertebrae) that form the spine in the back are cushioned by small, spongy disks. ...

Limping rat provides sciatica insights

... These roots are the parts of the nerve that pass through openings in the spine to the spinal cord. Surgical simulation of nerve compression in rats ... of Shamji's and Allen's experiments were published online in the journal spine . "If immune system activation is involved, and it turns out to be an ...

Moderate alcohol intake associated with bone protection

... analyzed BMD measurements taken at three hip sites and the lumbar spine in 1,182 men, 1,289 post-menopausal women, and 248 pre-menopausal women ... In contrast, the authors observed significantly lower BMD at the hip and spine in men who consumed more than two servings of liquor per day compared to ...

Adiponectin is a metabolic link between obesity and bone mineral density

... adulthood. The weaker vertebra model compression fractures of the lumbar spine in humans, among the most common type of fragility fracture associated ... high level of adiponectin impedes bone development at not only the lumbar spine but also the hip. Whether or not the delay in bone development resolves in ...

UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome

... members in UCR's Division of Biomedical Sciences, describe how dendritic spine development in mice with Fragile X is delayed by enzymes called matrix ... Fragile X mice treated with minocycline showed an increase of dendritic spine maturation in the hippocampus, a brain area that is critical for learning ...

Mayo Clinic study: Ossur's collars superior in immobilization and reduction of pressure

... and occipital tissue-interface pressure (TIP). Background: Cervical spine immobilization in major trauma patients is routinely carried out to ... the initiation of spinal precautions in all such patients before cervical spine clearance. Failure to achieve early spinal clearance predisposes the ...

Study shows some athletic men may risk low bone density

... compared to runners. 63 percent of the cyclists had osteopenia of the spine or hip compared with 19 percent of the runners. Cyclists were seven-times more likely to have osteopenia of the spine than the runners. Background facts: The risk of fracture is ...

Rare albino ratfish has eerie, silvery sheen

... Located on their back, just in front of the dorsal fin, ratfish have a spine several inches long that is serrated on one edge, needle sharp at the tip and delivers an irritating venom. The spine could be the reason the only predators to eat Puget Sound ratfish are ...

Little-known protein found to be key player

... worldwide. It's marked by a partial paralysis of the lower extremities due to defects in the body's longest cells, the neurons that run from the spine through the legs. Daga said atlastin's role in building and maintaining a healthy ER may help HSP researchers better understand why neurons are ...

Protein linked to mental retardation controls synapse maturation, plasticity, CSHL team finds

... There is no question, Van Aelst clarifies, that "defective OPHN1 signaling results in destabilization of synaptic AMPA receptors and dendritic spine structure, leading to impairment in synaptic plasticity and eventually loss of spines and NMDA receptors." This chain of events has been observed ...

3-D research model tackles prostate cancer spread

... a PhD student at IHBI, is studying the way cancer cells escape from the prostate through the bloodstream to form tumour colonies, most often in the spine and long bones. "It is an innovative study which uses a tissue engineering platform technology developed by IHBI's Professor Dietmar W. Hutmacher ...

Poor treatment for common vertebral compression fractures

... patients still have severe pain one year after the fracture. Vertebral compression fracture describes the pressing together of a vertebra in the spine such that its height is decreased. Approximately 15,000 patients suffer from vertebral compression fractures in Sweden each year, most of these ...

AJCN study shows moderate alcohol consumption related to stronger bones

... on bone mineral density in older people, and said that "moderate alcohol consumption was shown to contribute to stronger bones (measured as hip and spine bone mineral density). The positive effect on bone was most notable at 1-3 glasses of beer in men and more than 2 glasses of wine or liquor (but not ...

Genes identified that are linked to spinal disc degeneration

... gene forms indicate susceptibility. "This will tell us who should avoid physical loading, and in which people obesity could be a risk factor for spine problems," said Videman. But this could be a long process as disc degeneration is what's called polygenic, meaning it involves more than one gene. ...

Metastatic bone disease patients can walk in Lazarus' footsteps

... digital fluoroscopy imaging. The technique is similar to vertebroplasty, an interventional radiology treatment that has been used extensively in the spine to treat the pain of compression fractures. In the study, the average pain intensity score for patients based on the 11-point visual analog scale ...

Low levels of vitamin B12 may increase risk for neural tube defects

... that it is not known how B12 and folate might interact to influence the formation of the neural tube, the embryonic structure that gives rise to the spine and brain. They noted that the two vitamins are jointly involved with several key biochemical reactions, as well as with the synthesis of DNA. Lack ...

Building strong bones: Running may provide more benefits than resistance training, MU study finds

... body weight and composition, in men ages 19 to 45. After adjusting for differences in lean body mass, the researchers found that runners had greater spine BMD than cyclists. Lean body mass was positively associated with BMD in both resistance-trained individuals and cyclists but not in runners; ...

UNH researchers studying spiny dogfish, Gulf of Maine's mini shark

... year. The ages of fish are often determined by the annuli on otoliths (inner ear bones), dorsal or pectoral fin spines. The second dorsal fin spine was previously used to identify the ages of dogfish, but often with imprecise results due to normal calcification and damage to the structure. So ...

Italy's geologic history becomes a personal tale in Walter Alvarez's new book

... between the Cretaceous and Tertiary periods, when dinosaurs and many other creatures died out. But Alvarez also takes readers along the Apennine spine of Italy from Rome to Florence, jumping from there to the Alps, to explain how the Italian peninsula came to be. He refers to the Umbria-Marche ...

Researchers uncover mechanism of action of antibiotic able to reduce neuronal cell death in brain

... disease, epilepsy, stroke, dementia and malignant gliomas. Neurodegenerative diseases are caused by the deterioration of neurons in the brain and spine resulting in problems related to either movement or memory. For most patients, it may be months or years before symptoms are evident because a large ...

Genetic tags reveal secrets of memories' staying power in mice

... extinction learning. This indicated that the same neurons activated when a fear is learned are also activated when it is lost. The surge in mushroom spine capture of the receptors appeared within hours of learning and was gone after a few days, but appeared to be critical for cementing the memory. ...

New folic acid seal helps women choose enriched grain foods to help prevent birth defects

... two recent surveys show. Daily consumption of folic acid beginning before pregnancy is crucial because birth defects of the brain and spine known as neural tube defects (NTDs), such as spina bifida, can occur in the early weeks following conception, often before a woman knows she is ...

UT-Houston's Northrup and colleagues uncover genetic link to spina bifida

... bifida is the most common permanently disabling birth defect in the United States, according to the Spina Bifida Association. It happens when the spine of the baby fails to close during the first months of pregnancy. It occurs in seven out of 10,000 births in the United States. According to the ...

Study reveals 2 genes linked to disabling arthritis

... sclerosis and breast cancer. The most significant findings, however, were in ankylosing spondylitis, a type of arthritis that not only affects the spine but also can attack other joints and organs, including the heart, lungs and eyes. The condition afflicts an estimated one in 200 males and one in 500 ...

Ancient whale fall from California's Ao Nuevo Island one of youngest, most complete known

... small and unremarkable fossil whale - at 11 feet, it was less than half the size of today's smallest baleen whales. The bones, including skull, spine and ribs, were displayed at Long Marine Laboratory in Santa Cruz until the lab donated the partially articulated skeleton to the Museum of ...

Ancient whale fall from California's Año Nuevo Island one of youngest, most complete known

... small and unremarkable fossil whale - at 11 feet, it was less than half the size of today's smallest baleen whales. The bones, including skull, spine and ribs, were displayed at Long Marine Laboratory in Santa Cruz until the lab donated the partially articulated skeleton to the Museum of ...

Genome study shines light on genetic link to height

... of the skeleton, as scientists found that the T-to-C change in the genes DNA sequence correlates with an increased length of both the limbs and spine in young children. HMGA2 has also been implicated in certain forms of cancer. Thus, further studies may help dissect the relationship between normal ...

News tips from the Journal of Neuroscience

... filopodial formation. Reduction of ERM protein expression by small interfering RNA decreased the density and length of filopodia while accelerating spine maturation, whereas ectopic expression of constitutively active ezrin induced the formation of dendritic filopodia. KisspeptinGPR54 Signaling ...

Pourquié lab identifies genes involved in formation of vertebral precursors

... genes that shed light on the molecular basis of spine formation in the embryo. The paper was ... lab has long studied the formation of the spine and the role of an internal mechanism -- the ... a fundamental aspect of the architecture of the spine by demonstrating the implication of a large ...

Elderly spinal cord injuries increase five-fold in 30 years, Jefferson neurosurgeons find

... will be older than age 65 by the year 2040, and will likely impact spine surgeons and spinal cord rehabilitation centers as these patients become a ... at a meeting in Phoenix, Ariz. of the Joint Section on Disorders of the spine and Peripheral Nerves of the American Association of Neurological ....

Ferns provide model for tiny motors powered by evaporation

... is lifted off and that is used for the device. It resembles a curved spine with equally spaced ribs fanning outward from the spine. To make the ... of the ribs so that the tips move toward each other, straightening out the spine of the device. In this way, the closed device opens wide---it moves. ...

Human stem cells delay start of Lou Gehrig's disease in rats

... of cells - already being planned -- along the full length of the spine to affect upper body nerves and muscles as well might lead to longer ... Adult rats not yet showing symptoms were injected in the lower spine with human neural stem cells - cells that can in theory become any type ...

New roles for growth factors: Enticing nerve cells to muscles

... specific subgroup of motor neurons to connect to the muscles that line our spine and neck," says senior author Samuel Pfaff, Ph.D., a professor in the Gene ... bent your back." Earlier studies suggested that muscles lining the spine sent out chemical cues as a siren song for specific motor neurons known as ...

Long-term changes in experience cause neurons to sprout new long-lasting connections

... said the discovery of experience-dependent, persistent-type dendritic spine growth has broader implications for understanding learning. "We think ... itself, to understand the changes in the brain's wiring diagram caused by spine growth. ...

Tiny RNA molecules fine-tune the brain's synapses

... dendrites where synapses form. When neurons were exposed to miR-134, spine volume significantly decreased, weakening the synapse. When miR-134 was ... this inhibition was overcome and Limk1 became active again, enhancing spine growth. Greenberg believes that miR-134 ?and other microRNAs his lab is ...

Purdue scientists may have found key to halting spinal cord damage

... but no one has ever been sure which chemicals are responsible." When a spine is damaged, the change in its ability to function follows a well-defined pattern. In response to the initial shock, the spine immediately becomes completely nonfunctional but then starts to recover ...

Increased risk of osteoporosis associated with gene that one in five people have

... low bone density." The research team measured bone density in both the spine and the upper femur. The bone mass of the spine proved not to be affected by genetic variation in CYP1A1. "Our study ...

Human stem cell treatment restores motor function in paralyzed rats

... Rats paralyzed due to loss of blood flow to the spine returned to near normal ambulatory function six weeks after receiving grafts of human spinal stem cells (hSSCs), researchers from the University of ...
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