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Sequence in Biological News

Understanding how weeds are resistant to herbicides

... in the Keck Center at the U of I. The genetic sequence will allow scientists to study herbicide ... of having the genetic data. "Once we obtain the sequence of a resistance gene, we can develop molecular ... it is resistant or not because we know the gene sequence and we know the mutation and the mechanism." ...

ISU researchers find possible treatment for spinal muscular atrophy

... becomes mRNA by splicing out certain parts of the sequence that are non-coding, meaning they don't help the ... intronic sequences, sometimes referred to as junk sequence because it is originally copied from junk DNA. ... because of the presence of a specific intronic sequence in the gene or DNA. To make SMN2 behave as ...

Mystery E. coli genes essential for survival of many species

... the University of Dundee has examined the genome sequence of this workhorse of the laboratory and spotted ... Bacteriology . The effort over recent years to sequence genomes of various important species has ... work is a good example of where having a genome sequence opens up many possible avenues of enquiry. It ...

Landmark project to map genomics of complex ant systems

... Gerardo put together a project to not only sequence ant genomes for the first time, but also the ... species. Entering new territory Roche will sequence the DNA using its proprietary high-throughput ... millions of dollars and extensive manpower to sequence just one organism. "We're entering completely ...

Natural-born divers and the molecular traces of evolution

... pressure, they went on to study the molecular sequence of myoglobin in small aquatic mammals such as ... therefore it can be predicted if the amino acid sequence is known. Dr. Berenbrink's team have determined large parts of the myoglobin sequence for four different species of insectivores, and ...

CSHL scientists harness logic of 'Sudoku' math puzzle to vastly enhance genome-sequencing capability

... it is possible to use the Sudoku method to sequence more than a hundred thousand DNA samples," says ... as identification markers and thus tell which sequence belonged to which sample. "But this approach ... which pool contains which samples, we can link a sequence to an individual sample with high confidence," ...

Midget plant gets makeover

... just released a new version of the genome sequence of this model plant, which includes an array of ... and we've made extensive updates to the genome sequence based on new sequence data submitted to TAIR." In 2000, ...

Domestication of Capsicum annuum chile pepper provides insights into crop origin and evolution

... questions, Dr. Kim and his team examined DNA sequence variation and patterns at three nuclear loci in a ... of C. annuum. On the basis of patterns in the sequence data, Dr. Kim et al. hypothesize that chiles were ... among cultivated populations was reflected in DNA sequence variation. This separation suggests that seed ...

The SIB recognizes the next generation of bioinformaticians

... between protein residues entirely based on sequence data, using multiple sequence alignments of similar proteins. Dr. Burger has ... infer protein-protein interactions directly from sequence alignments with high accuracy. SIB 2009 Young ...

Scientists sequence genome of the N2-fixing, soil-living bacterium Azotobacter vinelandii

... and Virginia Tech, have completed the genome sequence of Azotobacter vinelandii , uncovering important ... a process called respiratory protection. The sequence of the bacteria's genome allowed the team of ... dehydrogenase and a formate dehydrogenase. The sequence also provided important information on the genes ...

New piece found in the puzzle of epigenetics

... an organism are not regulated solely by the DNA sequence of its genes: Superordinate regulatory mechanisms ... In humans this domain consists of 52 repeats of a sequence of seven amino acids. For RNA synthesis the ... amino acid serine at position 7 of this repeat sequence is provided with an additional phosphate group. ...

Caltech scientists reveal how neuronal activity is timed in brain's memory-making circuits

... in an environment is represented and stored as a sequence of point locations. If the rat visits the same ... ambiguous. Representing the rat trajectory as a sequence of segments oriented in space resolves such ... receive inputs from the hippocampus in a specific sequence rather than all at once," explains Siapas. In ...

Rapid approach to identify influenza A virus mutations and drug resistance developed

... a novel approach to uncover the complete sequence of any influenza A virus, including H1NI, with ... amplify full genomes of influenza A viruses and sequence them within a day, was developed at the Genome ... contains probes which can reveal the complete sequence of the flu virus from patient samples, it enables ...

A genome may reduce your carbon footprint

... a computer to cheaply store, access, and analyze sequence information, emphasis is increasingly being ... published study examined the impact of very cheap sequence data (approximately 1USD per genome) on ... of cheap sequencing capacity, neither complete sequence assembly nor gene annotation is required to apply ...

New genomic technique uncovers coral transcriptome

... emulsion PCR, and results in 2-5 fold greater 454 sequence output than in any previously reported attempts. ... "These tools allow for the rapid development of sequence resources for any organism at a low cost a few ... approximately 11,000 genes on the basis of sequence similarity with known proteins, over 30,000 ...

Genetic secrets of date palm unlocked by researchers at Weill Cornell Medical College in Qatar

... secrets. "We have generated a draft DNA sequence and initial assembly of the date palm using the ... offers data quality between that of the expressed sequence tag (EST) method and the traditional whole-genome ... his colleagues will continue to improve the draft sequence and publish their data. Meanwhile, they are ...

A genomic CluE for cloud computing

... over the internet, might be used to process DNA sequence data. "There is a new initiative by NSF to ... clusters of computers are a better option for DNA sequence analysis than local clusters of computers." ... is to develop the software required to analyze sequence data in parallel (on many computers ...

Bovine genome provides clues to possible new developments

... of researchers who have developed an annotated sequence of the cattle genome which could lead to better ... " Science ." The researchers used the complete sequence from a single Hereford cow and comparative genome ... the annotation process. Womack said the cattle sequence took six years to complete, annotate and analyze ...

New insights into progressive hearing loss

... has seen a disease-causing mutation in the mature sequence of a microRNA," says Dr Moreno-Pelayo. "This is ... code from A to T - in this tiny stretch of sequence is enough to lead to dramatic loss of hearing in ... in a vital region of seven letters in the mature sequence of miR96" says Dr Angeles Menca, the Spanish team ...

Rhythmic genomics -- the yeast metronome and the walk of life

... New genome sequence information from the humble baker's yeast has ... on their evolutionary journey. Ribosomal RNA sequence changes have been ticking away like clockwork for ... itself. However, even the slightest changes in sequence of these genes can be fatal. It is vital to ...

Evolutionary origin of bacterial chromosomes revealed

... A comprehensive comparison of the Agrobacterium sequence information with the genome sequences of other ... of various sizes. The scientists used the sequence information of the genomes of three types of ... to the efforts of the Agrobacterium Genome sequence Consortium and the wider research community, we ...

Genetic abnormality may increase risk of blood disorders

... in Nature Genetics , identifies a common genetic sequence abnormality that enhances the likelihood of ... out a genome-wide study to identify inherited DNA sequence changes that frequently occur in patients with ... authors, understanding the underlying inherited sequence partly explains the predisposition for acquiring ...

Saving wheat crops worldwide

... Improvement Center have identified a wheat gene sequence which provides protection against leaf rust, ... tests conducted after identifying the Lr34 gene sequence show it has provided partial but constant ... an immediate application is the use of the gene sequence to directly select and breed wheat plants that ...

Relationships in rank and file

... function of a gene or protein is to compare its sequence with the sequences of hundreds of other organisms ... letter by letter, their idea is to take the sequence neighbors surrounding each letter into account ... should be generally applicable in other areas of sequence searching ...

Eosinophils as markers for asthma

... test persons. The researchers found several sequence variants associated with asthma. "Two of the detected sequence variants are of significance for a biochemical ... know what mechanisms underlie the effect of these sequence variants on the inflammatory cells," Dr. Wjst ...

Tailor-made recombinant proteins in mammals

... this by converting a cysteine residue, one in a sequence of six core amino acids in a particular ... encoding those six residues from the sulfatase sequence into the DNA of the target protein we want to ... to occur." Bertozzi calls that six-residue sequence the aldehyde tag. "You just sit back and allow ...

Complete Genomics releases proof-of-concept data for its sequencing technology for the first time

... days. This represents the first human genome sequence produced with a third-generation technology and ... scientific community to analyze its unique genome sequence data set further, Complete Genomics has sent ... up its commercial genome center. It plans to sequence 1,000 genomes in the second half of 2009 and ...

Genome sequence shows sorghum's immense potential

... more diseases and pests. Breeders can use the sequence as a tool to blend desirable traits into more ... with sorghum sequencing. The sorghum genome sequence also has other uses. Sorghum's close cousin ... the weed. A third use of sorghum's genome sequence will be to gain insights into the reasons that ...

Sequencing of sorghum genome completed

... species and the human genome. By using paired sequence reads instead of single sequence reads, the scientists can jump over repeat ... will make it faster and far less expensive to sequence other complex genomes in the future." ...

CSHL scientists clarify editing error underlying genetic neurodegenerative disease

... these sites that didn't appear to have the right sequence of RNA bases to match U1. Experimental testing of ... with the first base of the target intron's RNA sequence that is, in the conventional way the scientists ... itself down to the next base in the intron's RNA sequence if this new arrangement allows more of U1's RNA ...

January-February GSA Bulletin media highlights

... study of the Nuvvuagittuq volcano-sedimentary sequence in the northeast Superior Province of northern ... an age of about 3.8 billion years old. The sequence contains recognizable volcanic and sedimentary ... 16 million years ago. Tonalites that envelop the sequence yield an age of 3661 4 million years ago and ...

UC San Diego and Genentech scientists develop potentially disruptive antibody sequencing technology

... Genentech have developed a new, quicker way to sequence monoclonal antibodies a process that is many ... method, which reduces the time required to sequence an unknown antibody to under 36 hours a ... level analysis is needed. So it is critical to sequence the antibodies for a variety of reasons, from ...

Just a little squeeze lets proteins assess DNA

... "Early Interrogation and Recognition of DNA sequence by Indirect Readout," in the December issue of ... the direct readout method to find the particular sequence of DNA that corresponded to enemy DNA. The ... DNA binding-proteins recognize a particular DNA sequence provides insight into key cellular processes ...

DOE Joint Genome Institute completes soybean genome

... percent of biodiesel production. "The genome sequence is the direct result of a memorandum of ... Preliminary scientific details emerging from the sequence analysis will be presented by Schmutz at the ... Mexico, December 8, 2008. The soybean genome sequence information can be browsed at ...

Research-based undergraduate course expands beyond Washington University

... hub for publicly available data. A DNA sequence is a succession of letters corresponding to the ... known as "finishing," is necessary because raw sequence data often has problem areas that can only be ... assembly errors, and low quality regions in the sequence data for their fosmid. Students then design and ...

Research consortium to sequence turkey genome

... consortium of researchers has begun an effort to sequence the genome of the domesticated turkey, Meleagris gallopavo. The genome sequence will be obtained using the Roche GS-FLX ... genome will be compared with the chicken genome sequence to examine similarities and differences in genome ...

New method provides panoramic view of protein-RNA interactions in living cells

... to identify, in a single experiment, every sequence within every strand of RNA to which proteins ... At the end of the day, they are left with the RNA sequence to which the protein was bound. They can then take these sequences to Rockefeller's high throughput sequence facility, and with the help of Research Support ...

Complete Genomics launches, becomes world's first large-scale human genome sequencing company

... Silicon Valley has allowed Complete Genomics to sequence its first complete human genome, providing ... Price Point "We will be the first company to sequence complete human genomes for less than $1,000 in ... DNA sequencing service in Q2 2009, it plans to sequence 1,000 genomes in the same year. The company will ...

Researchers develop new self-training gene prediction program for fungi

... heuristically defined parameters breaks the sequence into coding and non-coding regions. With this ... in statistical pattern recognition. When the new sequence breakdown coincides with the previous one, the ... with gene annotation right after the genomic sequence was in hand without spending time and effort to ...

NC State researchers get to root of parasite genome

... and colleagues have completed the genome sequence and genetic map of one of the world's most common ... paper describing the research. The resulting sequence data has been deposited in public databases, so ... nematodes, and the completion of the genome sequence will further empower researchers to ask highly ...
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(Date:9/1/2014)... Section of the XVIII International Botanical Congress took place ... held every six years and it is where the ... fungi and plants get together to debate and update ... This is the primary product of the meeting, the ... which was published in 2012. The other important product ...
(Date:8/31/2014)... the University of Warwick have discovered that ,good, cholesterol ... The substance, methylglyoxal - MG, was found to damage ... cholesterol from the body. , Low levels of ... disease, with increased levels of MG being common in ... , Supported by funding from the British Heart ...
(Date:8/31/2014)... test provides a fast and accurate tool to ... shows. The newly developed test (TAM-TB assay) is ... tuberculosis in children. The test features excellent specificity, ... with speed of a blood test. The promising ... of tuberculosis in children, particularly in tuberculosis-endemic regions. ...
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